SG11201710596RA - Pyrazole derivative or pharmaceutically acceptable salt thereof - Google Patents
Pyrazole derivative or pharmaceutically acceptable salt thereofInfo
- Publication number
- SG11201710596RA SG11201710596RA SG11201710596RA SG11201710596RA SG11201710596RA SG 11201710596R A SG11201710596R A SG 11201710596RA SG 11201710596R A SG11201710596R A SG 11201710596RA SG 11201710596R A SG11201710596R A SG 11201710596RA SG 11201710596R A SG11201710596R A SG 11201710596RA
- Authority
- SG
- Singapore
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- pyrazole derivative
- pyrazole
- derivative
- Prior art date
Links
- 150000003217 pyrazoles Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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- A61K31/4192—1,2,3-Triazoles
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- A61K31/4196—1,2,4-Triazoles
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- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
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- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- A61K31/5375—1,4-Oxazines, e.g. morpholine
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
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- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
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- Dermatology (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2015126046 | 2015-06-23 | ||
PCT/JP2016/068445 WO2016208602A1 (en) | 2015-06-23 | 2016-06-22 | Pyrazole derivative, or pharmaceutically acceptable salt thereof |
Publications (1)
Publication Number | Publication Date |
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SG11201710596RA true SG11201710596RA (en) | 2018-01-30 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201710596RA SG11201710596RA (en) | 2015-06-23 | 2016-06-22 | Pyrazole derivative or pharmaceutically acceptable salt thereof |
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US (1) | US10287251B2 (en) |
EP (2) | EP3315492B1 (en) |
JP (1) | JP6454418B2 (en) |
KR (1) | KR102655928B1 (en) |
CN (1) | CN107709301B (en) |
AU (1) | AU2016281346B2 (en) |
BR (1) | BR112017028125A2 (en) |
CA (1) | CA2988772A1 (en) |
ES (1) | ES2820839T3 (en) |
IL (1) | IL256339B (en) |
MX (1) | MX2017016876A (en) |
MY (1) | MY195177A (en) |
PH (1) | PH12017502254B1 (en) |
PL (1) | PL3315492T3 (en) |
RU (1) | RU2687245C1 (en) |
SG (1) | SG11201710596RA (en) |
TW (1) | TWI681956B (en) |
WO (1) | WO2016208602A1 (en) |
ZA (1) | ZA201708611B (en) |
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WO2018117166A1 (en) * | 2016-12-21 | 2018-06-28 | キッセイ薬品工業株式会社 | Thiazole derivative or pharmacologically acceptable salt of same |
JP6986955B2 (en) * | 2016-12-28 | 2021-12-22 | キッセイ薬品工業株式会社 | Method for producing pyrazole derivative |
CN112480005B (en) * | 2017-11-08 | 2022-08-19 | 北京嘉林药业股份有限公司 | Compounds and their use for treating cancer |
WO2021074281A1 (en) * | 2019-10-17 | 2021-04-22 | Givaudan Sa | Substituted azacyles as trmp8 modulators |
WO2023021012A1 (en) | 2021-08-16 | 2023-02-23 | Symrise Ag | Compositions |
CN114394934B (en) * | 2022-01-06 | 2023-06-13 | 苏州大学 | Pyrazole benzamide compound as well as preparation method and application thereof |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
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IL39092A (en) | 1971-04-22 | 1976-02-29 | Du Pont | Pyrazole derivatives and their use as plant growth regulants |
JP2000256358A (en) | 1999-03-10 | 2000-09-19 | Yamanouchi Pharmaceut Co Ltd | Pyrazole derivative |
DK1210344T3 (en) | 1999-08-19 | 2006-03-06 | Nps Pharma Inc | Heteropolycyclic Compounds and Their Uses as Metabotropic Glutamate Receptor Antagonists |
DE60112742T2 (en) * | 2000-05-19 | 2006-02-02 | Applied Research Systems Ars Holding N.V. | USE OF PYRAZONE DERIVATIVES FOR THE TREATMENT OF BARRENESS |
AU2001273040A1 (en) | 2000-06-27 | 2002-01-08 | Du Pont Pharmaceuticals Company | Factor xa inhibitors |
RS20050175A (en) | 2002-08-23 | 2007-09-21 | Rigel Pharmaceuticals Inc., | Pyridyl substituted heterocycles useful for treating or preventing hcv infection |
US20040215284A1 (en) | 2003-01-30 | 2004-10-28 | Recordati S.A. | Treatment of neuromuscular dysfunction of the lower urinary tract with selective mGlu5 antagonists |
ITMI20030151A1 (en) | 2003-01-30 | 2004-07-31 | Recordati Ind Chimica E Farma Ceutica S P A | USE OF SELECTIVE MGLU5 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF NEUROMUSCULAR DYSFUNCTIONS OF THE LOWER URINARY TRACT. |
US7115642B2 (en) | 2003-05-02 | 2006-10-03 | Rigel Pharmaceuticals, Inc. | Substituted diphenyl isoxazoles, pyrazoles and oxadiazoles useful for treating HCV infection |
US8329703B2 (en) | 2005-02-15 | 2012-12-11 | Xtl Biopharmaceuticals Ltd. | Pyrazole compounds |
WO2007017093A1 (en) | 2005-08-04 | 2007-02-15 | Bayer Healthcare Ag | Substituted 2-benzyloxy-benzoic acid amide derivatives |
JP2009515997A (en) | 2005-11-18 | 2009-04-16 | タケダ サン ディエゴ インコーポレイテッド | Glucokinase activator |
WO2009012430A1 (en) | 2007-07-18 | 2009-01-22 | Janssen Pharmaceutica N.V. | Sulfonamides as trpm8 modulators |
DE102007040243A1 (en) | 2007-08-25 | 2009-02-26 | Universität des Saarlandes | 17beta-hydroxysteriod dehydrogenase type 1 inhibitors for the treatment of hormone-dependent diseases |
EP2491034B1 (en) | 2009-10-23 | 2013-12-18 | Janssen Pharmaceutica, N.V. | Fused heterocyclic compounds as orexin receptor modulators |
US8680098B2 (en) | 2010-03-05 | 2014-03-25 | Janssen Pharmaceutica, Nv | Substituted aza-bicyclic imidazole derivatives useful as TRPM8 receptor modulators |
DE202011111014U1 (en) * | 2010-11-05 | 2018-05-02 | Senomyx, Inc. | Compounds useful as modulators of TRPM8 |
US9365588B2 (en) | 2011-11-04 | 2016-06-14 | Vertex Pharmaceuticals Incorporated | Benzoxazines as modulators of ion channels |
SG11201509244XA (en) | 2013-05-08 | 2015-12-30 | Kissei Pharmaceutical | Α-substituted glycineamide derivative |
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2016
- 2016-06-22 WO PCT/JP2016/068445 patent/WO2016208602A1/en active Application Filing
- 2016-06-22 JP JP2017524933A patent/JP6454418B2/en active Active
- 2016-06-22 MY MYPI2017704878A patent/MY195177A/en unknown
- 2016-06-22 BR BR112017028125-2A patent/BR112017028125A2/en not_active IP Right Cessation
- 2016-06-22 EP EP16814372.5A patent/EP3315492B1/en active Active
- 2016-06-22 SG SG11201710596RA patent/SG11201710596RA/en unknown
- 2016-06-22 RU RU2017145176A patent/RU2687245C1/en active
- 2016-06-22 US US15/736,016 patent/US10287251B2/en active Active
- 2016-06-22 CA CA2988772A patent/CA2988772A1/en not_active Abandoned
- 2016-06-22 ES ES16814372T patent/ES2820839T3/en active Active
- 2016-06-22 MX MX2017016876A patent/MX2017016876A/en unknown
- 2016-06-22 KR KR1020187002023A patent/KR102655928B1/en active IP Right Grant
- 2016-06-22 CN CN201680037397.9A patent/CN107709301B/en active Active
- 2016-06-22 TW TW105119545A patent/TWI681956B/en not_active IP Right Cessation
- 2016-06-22 EP EP20161313.0A patent/EP3686188B1/en active Active
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- 2016-06-22 PL PL16814372T patent/PL3315492T3/en unknown
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2017
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- 2017-12-14 IL IL256339A patent/IL256339B/en active IP Right Grant
- 2017-12-18 ZA ZA2017/08611A patent/ZA201708611B/en unknown
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JP6454418B2 (en) | 2019-01-16 |
US10287251B2 (en) | 2019-05-14 |
US20180170879A1 (en) | 2018-06-21 |
IL256339A (en) | 2018-02-28 |
TWI681956B (en) | 2020-01-11 |
AU2016281346B2 (en) | 2020-01-02 |
TW201712004A (en) | 2017-04-01 |
EP3315492A1 (en) | 2018-05-02 |
EP3686188B1 (en) | 2022-04-06 |
IL256339B (en) | 2020-03-31 |
BR112017028125A2 (en) | 2018-08-28 |
JPWO2016208602A1 (en) | 2018-04-12 |
EP3315492A4 (en) | 2018-12-19 |
PH12017502254A1 (en) | 2018-06-11 |
ES2820839T3 (en) | 2021-04-22 |
PL3315492T3 (en) | 2021-04-06 |
CN107709301B (en) | 2021-06-22 |
ZA201708611B (en) | 2019-05-29 |
KR102655928B1 (en) | 2024-04-09 |
KR20180015262A (en) | 2018-02-12 |
CN107709301A (en) | 2018-02-16 |
EP3315492B1 (en) | 2020-09-16 |
CA2988772A1 (en) | 2016-12-29 |
RU2687245C1 (en) | 2019-05-08 |
EP3686188A1 (en) | 2020-07-29 |
AU2016281346A1 (en) | 2018-01-18 |
PH12017502254B1 (en) | 2018-06-11 |
WO2016208602A1 (en) | 2016-12-29 |
MY195177A (en) | 2023-01-11 |
MX2017016876A (en) | 2018-04-10 |
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