SG11201701928RA - Antibacterial use of halogenated salicylanilides - Google Patents

Antibacterial use of halogenated salicylanilides

Info

Publication number
SG11201701928RA
SG11201701928RA SG11201701928RA SG11201701928RA SG11201701928RA SG 11201701928R A SG11201701928R A SG 11201701928RA SG 11201701928R A SG11201701928R A SG 11201701928RA SG 11201701928R A SG11201701928R A SG 11201701928RA SG 11201701928R A SG11201701928R A SG 11201701928RA
Authority
SG
Singapore
Prior art keywords
halogenated salicylanilides
antibacterial use
antibacterial
salicylanilides
halogenated
Prior art date
Application number
SG11201701928RA
Inventor
Emilie Flora Aurore Delavenne
Daniel Jean Jacques Simon
Morten Otto Alexander Sommer
Rasmus Vendler Toft-Kehler
Original Assignee
Antibiotx Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antibiotx Aps filed Critical Antibiotx Aps
Publication of SG11201701928RA publication Critical patent/SG11201701928RA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/609—Amides, e.g. salicylamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
SG11201701928RA 2014-09-12 2015-09-08 Antibacterial use of halogenated salicylanilides SG11201701928RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE1451054 2014-09-12
PCT/EP2015/070495 WO2016038035A1 (en) 2014-09-12 2015-09-08 Antibacterial use of halogenated salicylanilides

Publications (1)

Publication Number Publication Date
SG11201701928RA true SG11201701928RA (en) 2017-04-27

Family

ID=54072831

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201701928RA SG11201701928RA (en) 2014-09-12 2015-09-08 Antibacterial use of halogenated salicylanilides

Country Status (19)

Country Link
US (6) US20170258816A1 (en)
EP (3) EP3010511B1 (en)
JP (3) JP2017529393A (en)
KR (1) KR20170078600A (en)
CN (1) CN106999505A (en)
AU (1) AU2015314287B2 (en)
BR (1) BR112017004889A2 (en)
CA (1) CA2960331A1 (en)
DK (1) DK3010511T3 (en)
EA (1) EA032899B1 (en)
ES (2) ES2661000T3 (en)
HK (1) HK1223277A1 (en)
IL (1) IL250988A0 (en)
MX (1) MX2017003251A (en)
PH (1) PH12017500463B1 (en)
PL (1) PL3010511T3 (en)
SG (1) SG11201701928RA (en)
TR (1) TR201802762T4 (en)
WO (1) WO2016038035A1 (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2017003251A (en) 2014-09-12 2017-12-20 Antibiotx Aps Antibacterial use of halogenated salicylanilides.
GB201509326D0 (en) 2015-05-29 2015-07-15 Antibio Tx Aps Novel use
GB201604484D0 (en) 2016-03-16 2016-04-27 Antibiotx Aps And Københavns Uni University Of Copenhagen Topical antibacterial compositions
EP3484481B1 (en) 2016-07-15 2021-01-20 The Scripps Research Institute Methods for use in the treatment of clostridium difficile
GB201615693D0 (en) 2016-09-15 2016-11-02 Combinatorx Infection Ltd Combinations
US11147779B2 (en) * 2017-03-21 2021-10-19 Supreet K. Deshpande Therapeutic agent for phosphodiesterase inhibition and its related disorders
EP3403652A1 (en) 2017-05-18 2018-11-21 Veterinärmedizinische Universität Wien Prevention and treatment of fibroblast growth factor 23 (fgf23)-associated disorders including chronic kidney disease (ckd)
GB201713653D0 (en) * 2017-08-24 2017-10-11 Antibiotx As Dosage regimen
ES2979393T3 (en) * 2017-09-15 2024-09-25 Union Therapeutics As Antimicrobial composition
GB201805453D0 (en) * 2018-04-03 2018-05-16 Antibiotx As Novel use
WO2019222349A1 (en) * 2018-05-15 2019-11-21 Dana-Farber Cancer Institute, Inc. Compounds for treating dengue virus infections and other infections
GB201813876D0 (en) 2018-08-24 2018-10-10 Antibiotx As Treatment
WO2020072386A1 (en) * 2018-10-02 2020-04-09 The United States Government As Represented By The Department Of Veterans Affairs Spak kinase inhibitors as neuroprotective agents
WO2020089467A1 (en) 2018-11-02 2020-05-07 UNION therapeutics A/S Dosage regimen
US20210379085A1 (en) 2018-11-02 2021-12-09 UNION therapeutics A/S Halogenated salicylanilides for treating the symptoms of dermatitis
CN109331025A (en) * 2018-11-22 2019-02-15 华中农业大学 Application of the oxyclozanide in the drug for preparing anti-streptococcus suis
US11419834B2 (en) 2019-02-25 2022-08-23 Rhode Island Hospital Methods for treating diseases or infections caused by or associated with H. pylori using a halogenated salicylanilide
WO2020176067A1 (en) 2019-02-25 2020-09-03 Rhode Island Hospital Methods for treating diseases or infections caused by or associated with h. pylori using a halogenated salicylanilide
CN111150725A (en) * 2019-10-31 2020-05-15 天津国际生物医药联合研究院 Potential application of closantel sodium in resisting mycobacterium infection
EP4084785A1 (en) * 2020-02-21 2022-11-09 Yourchoice Therapeutics, Inc. Use of nicolsamide formulations for antiviral therapy
US20230190685A1 (en) 2020-04-01 2023-06-22 UNION therapeutics A/S Formulation
US11045434B1 (en) 2020-04-01 2021-06-29 UNION therapeutics A/S Niclosamide formulations for treating disease
AU2021248603A1 (en) 2020-04-01 2022-11-10 UNION therapeutics A/S Treatment
WO2022076565A1 (en) 2020-10-07 2022-04-14 Sorrento Therapeutics, Inc. Salicylanilide analogs for use in the treatment of coronavirus
GB202102488D0 (en) 2021-02-22 2021-04-07 Union Therapeutics As Treatment
WO2022204519A1 (en) 2021-03-26 2022-09-29 The United States Government As Represented By The Department Of Veterans Affairs Use of zt-1a and analogs thereof to prevent and/or treat neurodegenerative and neurocognitive disorders
WO2024154719A1 (en) * 2023-01-16 2024-07-25 国立研究開発法人科学技術振興機構 Antibacterial composition, pharmaceutical agent, and antibacterial method
CN117105809B (en) * 2023-10-20 2024-05-03 中国农业大学 Benzanilide compound and preparation method and application thereof

Family Cites Families (136)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2731386A (en) 1951-09-06 1956-01-17 Wallace & Tiernan Company Inc Antifungal composition
US3152039A (en) 1960-11-23 1964-10-06 Dow Chemical Co Germicidal compositions
FR1340175A (en) 1962-03-06 1963-10-18 Procter & Gamble New bactericidal compositions
DE1527638C3 (en) 1966-06-15 1974-01-31 Gesellschaft Zur Foerderung Der Eisenhuettentechnik Mbh, 4000 Duesseldorf Device for edging and moving rolling stock (blocks, slabs, etc.) on roller tables in rolling mills
US3674850A (en) * 1969-12-07 1972-07-04 Lever Brothers Ltd Substituted salicylanilides
US3914418A (en) * 1971-09-02 1975-10-21 Merck & Co Inc Methods of controlling liver fluke infections
GB1421589A (en) 1972-03-07 1976-01-21 Janssen Pharmaceutica Nv Salicylanilide derivatives
DE2557615C2 (en) 1975-12-20 1985-08-14 Bayer Ag, 5090 Leverkusen New niclosamide suspension formulations
SU597671A1 (en) 1976-10-07 1978-03-15 Предприятие П/Я М-5400 Method of purifying commercial 3,4',5-tribromsalicylanilide
JPS55129256A (en) 1979-02-28 1980-10-06 Isao Ozawa Antifungal compound
US4287191A (en) 1980-04-14 1981-09-01 The Research Foundation Of State University Of New York Novel salicylanilides and microbiocidal compositions and uses thereof
US4358443A (en) 1980-04-14 1982-11-09 The Research Foundation Of State University Of New York Method and composition for controlling the growth of microorganisms
US4560549A (en) 1983-08-24 1985-12-24 Lever Brothers Company Method of relieving pain and inflammatory conditions employing substituted salicylamides
US4742083A (en) 1983-08-24 1988-05-03 Lever Brothers Company Method of relieving pain and inflammatory conditions employing substituted salicylamides
IL77224A (en) 1984-12-12 1989-09-10 Euro Celtique Sa Antibacterial cream
US4939132A (en) 1985-04-15 1990-07-03 The Research Foundation Of State University Of New York Novel 5-alkylsulfonylsalicylanilides and microbiocidal compositions for controlling the growth of microorganisms
US4883660A (en) 1988-10-17 1989-11-28 Thames Pharmacal Co., Inc. Gel bases for pharmaceutical compositions
DK0487973T3 (en) 1990-11-26 1996-07-29 Bayer Ag Topical lotion containing niclosamide
AU4399296A (en) 1994-12-19 1996-07-10 Lauteral Limited A combination product comprising nitazoxanide and an anti-ulcer agent
EP1174439B1 (en) 1996-08-21 2008-10-08 Migenix Inc. Compositions and methods for treating infections using analogues of indolicidin
US5958911A (en) 1996-11-05 1999-09-28 The Research Foundation Of State University Of New York Method of relieving inflammation by using 5-alkylsulfonylsalicylanilides
CA2293683A1 (en) 1997-06-11 1998-12-17 Bayer Aktiengesellschaft Anthelmintic compositions
US6117859A (en) 1997-11-04 2000-09-12 The Research Foundation Of State University Of New York Method of relieving chronic inflammation by using 5-alkylsulfonylsalicylanilides
DE19843222A1 (en) 1998-09-22 2000-03-30 Hassan Jomaa Use of organophosphorus compounds for the therapeutic and prophylactic treatment of infections
TR200002965T2 (en) 1998-04-14 2001-05-21 Jomaa,Hassan The use of organophosphorus preparations for the therapeutic and prophylactic treatment of infections
DE19843223A1 (en) 1998-09-22 2000-03-30 Hassan Jomaa Organophosphorus compounds and their use
DE19828097A1 (en) 1998-06-24 1999-12-30 Hassan Jomaa Identifying antiparasitic agents used to treat or prevent parasitic infections, especially malaria, sleeping sickness and leishmaniosis
DE69902526T2 (en) 1998-05-18 2003-04-03 Pharmacia & Upjohn Co., Kalamazoo IMPROVING THE ANTIBACTERIAL EFFECT OF OXAZOLIDINONE BY ARGININE DERIVATIVES
US6399629B1 (en) 1998-06-01 2002-06-04 Microcide Pharmaceuticals, Inc. Efflux pump inhibitors
HUP0102782A3 (en) 1998-06-19 2002-12-28 Smithkline Beecham Corp Salycilanilide as inhibitors of transcription factor nf-kb
US6753324B2 (en) 1998-07-15 2004-06-22 Hassan Jomaa Phosphorous organic compounds and their use
AP2001002051A0 (en) 1998-07-15 2001-03-31 Hassan Jomaa Phosphorous organic compounds and their use.
DE19843360A1 (en) 1998-09-22 2000-03-30 Hassan Jomaa New phosphororganic compounds; useful for treatment of bacterial, viral and parasitic infection, and as herbicides or for treating infections in plants
DE19843334A1 (en) 1998-09-22 2000-03-30 Hassan Jomaa New organosulfinic acid and organosulfonic acid derivatives useful in medicine against viral, bacterial, fungal and parasiticidal infections and as herbicides, plant fungicides and plant bactericides
DE19843383A1 (en) 1998-09-22 2000-03-30 Hassan Jomaa New amino and imino substituted organo-phosphorus compounds useful in medicine against viral, bacterial, fungal and parasiticidal infections and as herbicides, plant fungicides and plant bactericides
DE19854403A1 (en) 1998-11-25 2000-05-31 Hassan Jomaa Organophosphorus compounds and their use
DE19859426A1 (en) 1998-12-22 2000-07-06 Hassan Jomaa Use of organophosphorus compounds for the therapeutic and prophylactic treatment of infections
DE19902924A1 (en) 1999-01-26 2000-08-03 Hassan Jomaa Use of organophosphorus compounds for the prophylactic and therapeutic treatment of infections
DE19903398A1 (en) 1999-01-29 2000-08-10 Hassan Jomaa Use of thiadiazole derivatives for the prophylactic and therapeutic treatment of infections
CH693625A5 (en) 1999-02-18 2003-11-28 Inpharma Sa Pharmaceutical compositions containing compounds of promoter activity of absorption of active ingredients.
WO2001060829A1 (en) 2000-02-18 2001-08-23 Jomaa Pharmaka Gmbh Phosphororganic compounds and the use thereof
US20020068014A1 (en) 2000-02-18 2002-06-06 Haught John Christian Antibacterial agents and compositions, methods and systems employing same
WO2001093872A1 (en) 2000-06-08 2001-12-13 Jomaa Pharmaka Gmbh Use of organophosphorous hydroxamic acid derivatives for producing medicaments
KR100827937B1 (en) 2000-07-19 2008-05-09 유니티카 가부시끼가이샤 Physiologically functional foods or cosmetics containing sphingoglycolipids and processes for their production
US6774100B2 (en) 2000-12-06 2004-08-10 Imaginative Research Associates, Inc. Anhydrous creams, lotions and gels
KR101088557B1 (en) 2000-12-18 2011-12-05 가부시키가이샤 이야쿠 분지 셋케이 겐쿠쇼 Inhibitors against the production and release of inflammatory cytokines
US6830758B2 (en) 2001-04-02 2004-12-14 Lectec Corporation Psoriasis patch
US20020192273A1 (en) 2001-06-15 2002-12-19 Teri Buseman Therapeutic patch useful for the treatment of hemorrhoids
US20040071757A1 (en) 2001-11-20 2004-04-15 David Rolf Inhalation antiviral patch
GB2386066A (en) 2002-02-28 2003-09-10 Norbrook Lab Ltd Long-acting parasiticidal composition with improved bioavailability comprising a salicylanilide, a further anti-parasitic compound & a polymeric species
RU2227025C2 (en) 2002-05-21 2004-04-20 ЗАО "Агроветсервис" Antiparasitic preparation with broad spectrum of effect
TW200402291A (en) 2002-06-06 2004-02-16 Inst Med Molecular Design Inc Antiallergic
WO2004006906A2 (en) 2002-07-15 2004-01-22 Combinatorx, Incorporated Methods for the treatment of neoplasms
WO2004047842A1 (en) 2002-11-28 2004-06-10 Moore, Bronwyn Treatment of immune system dysfunction
WO2004062600A2 (en) 2003-01-08 2004-07-29 Lectec Corporation Antiviral patch
JP4446678B2 (en) * 2003-05-08 2010-04-07 株式会社ノエビア Antibacterial agent
CA2538429A1 (en) * 2003-09-16 2005-03-24 Astellas Pharma Inc. Antibacterial drug for propionibacterium acnes
US20070059351A1 (en) 2003-10-17 2007-03-15 Murrell George A C Transdermal patches containing a nitric oxide-donor and a second active agent and associated methods
US7666444B2 (en) 2004-02-02 2010-02-23 Wyeth Antiparasitic composition
US8198326B2 (en) * 2004-09-07 2012-06-12 3M Innovative Properties Company Phenolic antiseptic compositions and methods of use
US20060222692A1 (en) 2005-03-31 2006-10-05 Fairfield Clinical Trials Llc Method and compositions for transdermal administration of antimicrobial medications
NZ563946A (en) 2005-06-03 2012-02-24 Acrux Dds Pty Ltd Testosterone containing non-occlusive transdermal drug delivery composition for application to the arm pit / axilla
JP4920206B2 (en) 2005-06-30 2012-04-18 ライオン株式会社 External preparation composition and patch, and percutaneous absorption composition of drug
GB0525093D0 (en) 2005-12-09 2006-01-18 Norbrook Lab Ltd Veterinary composition
US7727513B2 (en) * 2005-12-15 2010-06-01 Kimberly-Clark Worldwide, Inc. Method for screening for bacterial conjunctivitis
US20070254036A1 (en) 2006-04-13 2007-11-01 Besins Healthcare Sa Treatment of menopause associated symptoms
WO2008006848A1 (en) 2006-07-13 2008-01-17 Galderma Research & Development Composition comprising a retinoid and benzoyl peroxide
WO2008021088A2 (en) 2006-08-08 2008-02-21 The Regents Of The University Of Californina Salicylanilides enhance oral delivery of therapeutic peptides
US20090016990A1 (en) 2007-01-24 2009-01-15 Alberte Randall S Antimicrobial Compositions
WO2008133982A2 (en) 2007-04-27 2008-11-06 Lectec Corporation Adhesive patch with aversive agent
GB2449973B8 (en) * 2007-05-31 2010-01-06 Syntopix Group Plc Antibacterial & anti-acne formulations containing dialkyl sulphosuccinates
GB0711957D0 (en) * 2007-06-21 2007-08-01 Syntopix Ltd Formulations
ES2324192B1 (en) * 2008-01-30 2010-06-17 PUIG BEAUTY & FASHION GROUP, S.L. PEPTIDIC DERIVATIVES USEFUL IN THE TREATMENT, CARE OR CLEANING OF THE SKIN, MUCOSA, LEATHER HAIR OR NAILS.
US20110105976A1 (en) 2008-03-07 2011-05-05 Judd Berlin Hand sanitizing patch
WO2009140215A2 (en) 2008-05-11 2009-11-19 Geraghty, Erin Method for treating drug-resistant bacterial and other infections with clioquinol, phanquinone, and related compounds
US20100029781A1 (en) 2008-06-04 2010-02-04 Morris Jerome A Methods for preparation of anti-acne formulation and compositions prepared thereby
US20110117154A1 (en) 2008-07-07 2011-05-19 Activbiotics Pharma, Llc Use of rifalazil to treat colonic disorders
EP2143421A1 (en) 2008-07-07 2010-01-13 Almirall Hermal GmbH Topical composition for the treatment of actinic keratosis
US8846646B2 (en) 2008-10-03 2014-09-30 Winlind Skincare, Llc Topical treatment of skin infection
EP2177208A1 (en) * 2008-10-17 2010-04-21 Ferrer Internacional, S.A. Pharmaceutical topical compositions
JP2012509932A (en) 2008-11-26 2012-04-26 ビロブロック エスアー Method for inhibiting gram-positive bacteria using nonphospholipid lipid vesicles
GB2465633A (en) 2008-12-01 2010-06-02 Syntopix Ltd Anti-acne formulation
GB2456376A (en) * 2008-12-22 2009-07-15 Syntopix Ltd Antibacterial/anti-acne formulations comprising a halogenated salicylanilide in combination with one or more anti-acne agents
US20100286101A1 (en) 2009-05-07 2010-11-11 Jason Carbol Pharmaceutical composition including a corticosteroid and a vitamin d analog having improved stability
TW201103904A (en) 2009-06-11 2011-02-01 Hoffmann La Roche Janus kinase inhibitor compounds and methods
WO2011035321A1 (en) 2009-09-21 2011-03-24 Duke University Treatment of wnt/frizzled-related diseases
GB2477914B (en) 2010-02-12 2012-01-04 Univ Newcastle Compounds and methods for biofilm disruption and prevention
BRPI1002601E2 (en) 2010-06-01 2020-06-30 Embrapa Pesquisa Agropecuaria nanostructured composition for veterinary use for drug administration
FR2961810B1 (en) * 2010-06-29 2012-07-06 Galderma Res & Dev METRONIDAZOLE ESTERS FOR TREATING ROSACEA
JP5518595B2 (en) * 2010-06-30 2014-06-11 日本エンバイロケミカルズ株式会社 Industrial antiseptic and antifouling composition
GB201015079D0 (en) * 2010-09-10 2010-10-27 Helperby Therapeutics Ltd Novel use
DE102010054149A1 (en) 2010-12-10 2012-06-14 Merck Patent Gmbh 2-pyrones
ES2647072T3 (en) 2011-04-18 2017-12-19 Max-Delbrück-Centrum Für Molekulare Medizin In Der Helmholtz-Gemeinschaft Niclosamide for the treatment of cancer metastasis
US9572820B2 (en) 2011-05-10 2017-02-21 Stc.Unm Methods of treating autophagy-associated disorders and related pharmaceutical compositions, diagnostics, screening techniques and kits
CA2846850C (en) 2011-08-26 2019-12-03 Ohio University Combination of d-amino acid and tetrakis hydroxymethyl phosphonium sulfate for treating sulfate reducing bacteria biofilms
FR2991173B1 (en) 2012-06-04 2015-11-06 Virbac VETERINARY COMPOSITION WITH OXYCLOZANIDE BASED SKIN ADMINISTRATION
EP2902479A4 (en) * 2012-09-26 2016-06-08 Toyo Seikan Group Holdings Ltd Culture medium for food poisoning bacteria, and method for detecting food poisoning bacteria
US20150250808A1 (en) 2012-10-15 2015-09-10 Vojo P. Deretic Treatment of autophagy-based disorders and related pharmaceutical compositions, diagnostic and screening assays and kits
US9446131B2 (en) 2013-01-31 2016-09-20 Merz Pharmaceuticals, Llc Topical compositions and methods for making and using same
CN111905104A (en) 2013-02-08 2020-11-10 罗达制药公司 Method of treating topical microbial infections
EP2956437B1 (en) 2013-02-15 2023-05-10 Technische Universität Berlin Albicidin derivatives for the treatment of bacterial infections
CN105358141A (en) 2013-05-01 2016-02-24 尼奥酷里私人有限公司 Methods for treating bacterial infections
WO2014200705A1 (en) 2013-06-14 2014-12-18 Stc.Unm Treatment of autophagy-related disorders
EP2839828A1 (en) 2013-08-23 2015-02-25 Nitto Denko Corporation Compunds and formulations for the treatment of wounds
US10059752B2 (en) 2013-10-14 2018-08-28 University Of Houston System Esculentin 1a derivatives and uses thereof
IN2013MU03583A (en) 2013-11-14 2015-07-31 Cipla Ltd
WO2015143654A1 (en) 2014-03-26 2015-10-01 Merck Sharp & Dohme Corp. TrkA KINASE INHIBITORS,COMPOSITIONS AND METHODS THEREOF
EP3473630B1 (en) 2014-07-02 2021-01-13 Xavier University Of Louisiana Boron-based prodrug strategy for increased bioavailability and lower-dosage requirements for drug molecules containing at least one phenol (or aromatic hydroxyl) group
WO2016036839A1 (en) 2014-09-02 2016-03-10 The Arizona Board Of Regents On Behalf Of The University Of Arizona Compositions and methods for treating gonorrhea
MX2017003251A (en) 2014-09-12 2017-12-20 Antibiotx Aps Antibacterial use of halogenated salicylanilides.
CN107635563A (en) 2014-11-17 2018-01-26 维多利亚联结有限公司 Antimicrobial compound
EP3020398A1 (en) 2014-11-17 2016-05-18 Nitto Denko Corporation Compounds and formulations for reducing scarring
US10213478B2 (en) 2014-11-24 2019-02-26 The Translational Genomics Research Institute Compositions and methods for the treatment of fungal infections
CN104430338B (en) 2014-12-08 2016-08-31 江苏艾津农化有限责任公司 Niclosamide ethanolamine salt wettable powder agent and its preparation method and application
WO2016138286A1 (en) 2015-02-26 2016-09-01 Stc.Unm Irgm and precision autophagy controls for antimicrobial and inflammatory disease states and methods of detection of autophagy
WO2016144979A1 (en) 2015-03-09 2016-09-15 The Children's Mercy Hospital Dermatophytosis prophylaxis and treatment
EP3267990A4 (en) 2015-03-10 2018-09-05 ELC Management LLC Methods and compositions for treating skin to resolve inflammation and screening for actives that stimulate pro-resolution pathways
GB2542873A (en) 2015-04-16 2017-04-05 Elc Man Llc Unit dose packages, compositions, and treatment regimens to deliver pro-resolution pathway stimulators to keratin surfaces
GB201509326D0 (en) 2015-05-29 2015-07-15 Antibio Tx Aps Novel use
US20190070154A1 (en) 2015-06-24 2019-03-07 Duke University New methods of use for an anti-diarrhea agent
WO2016210289A1 (en) 2015-06-24 2016-12-29 Duke University Chemical modulators of signaling pathways and therapeutic use
CN109562137A (en) 2015-09-01 2019-04-02 第波生物公司 For treating the method and composition for reacting the related patient's condition with abnormal inflammatory
GB201604484D0 (en) 2016-03-16 2016-04-27 Antibiotx Aps And Københavns Uni University Of Copenhagen Topical antibacterial compositions
GB201615693D0 (en) 2016-09-15 2016-11-02 Combinatorx Infection Ltd Combinations
EP3576755A4 (en) 2017-02-02 2020-12-02 McMaster University Bicarbonate as a potentiator for antimicrobial agents
US11709169B2 (en) 2017-02-07 2023-07-25 National Jewish Health Lipid abnormalities and association with atopic allergic diseases
US11147779B2 (en) 2017-03-21 2021-10-19 Supreet K. Deshpande Therapeutic agent for phosphodiesterase inhibition and its related disorders
GB201713653D0 (en) 2017-08-24 2017-10-11 Antibiotx As Dosage regimen
GB201805453D0 (en) 2018-04-03 2018-05-16 Antibiotx As Novel use
GB201813876D0 (en) 2018-08-24 2018-10-10 Antibiotx As Treatment
US20210369650A1 (en) 2018-11-02 2021-12-02 UNION therapeutics A/S Treatment of inflammatory conditions
US11419834B2 (en) 2019-02-25 2022-08-23 Rhode Island Hospital Methods for treating diseases or infections caused by or associated with H. pylori using a halogenated salicylanilide
WO2020176067A1 (en) 2019-02-25 2020-09-03 Rhode Island Hospital Methods for treating diseases or infections caused by or associated with h. pylori using a halogenated salicylanilide
US20210114973A1 (en) 2019-10-18 2021-04-22 First Wave Bio, Inc. Pharmaceutical formulations
US20230190685A1 (en) 2020-04-01 2023-06-22 UNION therapeutics A/S Formulation
US11045434B1 (en) 2020-04-01 2021-06-29 UNION therapeutics A/S Niclosamide formulations for treating disease

Also Published As

Publication number Publication date
MX2017003251A (en) 2017-12-20
EP3338783A1 (en) 2018-06-27
EP3010511A1 (en) 2016-04-27
US10758553B2 (en) 2020-09-01
EP3338783B1 (en) 2024-01-24
US11331327B2 (en) 2022-05-17
US20170258816A1 (en) 2017-09-14
CA2960331A1 (en) 2016-03-17
US20190099433A1 (en) 2019-04-04
WO2016038035A1 (en) 2016-03-17
JP2017529393A (en) 2017-10-05
EA032899B1 (en) 2019-07-31
KR20170078600A (en) 2017-07-07
JP2023040096A (en) 2023-03-22
AU2015314287A1 (en) 2017-03-30
HK1223277A1 (en) 2017-07-28
US11324761B2 (en) 2022-05-10
AU2015314287B2 (en) 2019-04-18
EP3338783C0 (en) 2024-01-24
EA201790345A1 (en) 2017-07-31
IL250988A0 (en) 2017-04-30
ES2970434T3 (en) 2024-05-28
DK3010511T3 (en) 2018-03-05
PL3010511T3 (en) 2018-07-31
BR112017004889A2 (en) 2017-12-05
PH12017500463A1 (en) 2017-07-31
US9949988B2 (en) 2018-04-24
US11285164B2 (en) 2022-03-29
JP2021075567A (en) 2021-05-20
PH12017500463B1 (en) 2017-07-31
EP3010511B1 (en) 2018-02-14
US20200306271A1 (en) 2020-10-01
US20170326160A1 (en) 2017-11-16
CN106999505A (en) 2017-08-01
EP3967312A1 (en) 2022-03-16
US20200306270A1 (en) 2020-10-01
US20200306269A1 (en) 2020-10-01
ES2661000T3 (en) 2018-03-27
TR201802762T4 (en) 2018-03-21

Similar Documents

Publication Publication Date Title
IL250988A0 (en) Antibacterial use of halogenated salicylanilides
IL273065A (en) Sulfonylureas and related compounds and use of same
IL247072A0 (en) Medical use
SG11201609652RA (en) Treatment of polybacterials infections
HK1250052A1 (en) Mechanisms of antimicrobial susceptibility
IL283335B (en) Dihydropyrimidin-2-one compounds and medical use thereof
ZA201606715B (en) Antibacterial compounds
HK1231380A1 (en) Treatment of severe hypertriglyceridemia
GB201402267D0 (en) Antibacterial agents
PL3184492T3 (en) Antiseptic formulation
IL250405A0 (en) Antibacterial sideromycins
PL3146105T3 (en) Elastic bandage
GB201403170D0 (en) Preparation of antibacterial bisbenzimidazoles
GB201516610D0 (en) Antibacterial compounds and new uses thereof
GB201417939D0 (en) Antibacterial compounds
GB201417941D0 (en) Antibacterial compounds
GB201413411D0 (en) Novel compounds and their use
GB201414205D0 (en) Antibacterial compounds
AU2014903020A0 (en) Antibacterial Agent
GB201401407D0 (en) Antibacterial Compounds