SG11201701585VA - Mutant microorganisms resistant to lactose killing - Google Patents
Mutant microorganisms resistant to lactose killingInfo
- Publication number
- SG11201701585VA SG11201701585VA SG11201701585VA SG11201701585VA SG11201701585VA SG 11201701585V A SG11201701585V A SG 11201701585VA SG 11201701585V A SG11201701585V A SG 11201701585VA SG 11201701585V A SG11201701585V A SG 11201701585VA SG 11201701585V A SG11201701585V A SG 11201701585VA
- Authority
- SG
- Singapore
- Prior art keywords
- mutant microorganisms
- microorganisms resistant
- lactose killing
- killing
- lactose
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/12—Disaccharides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01022—Lactose synthase (2.4.1.22)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14193151 | 2014-11-14 | ||
| PCT/EP2015/076449 WO2016075243A1 (en) | 2014-11-14 | 2015-11-12 | Mutant microorganisms resistant to lactose killing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201701585VA true SG11201701585VA (en) | 2017-05-30 |
Family
ID=51893928
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201701585VA SG11201701585VA (en) | 2014-11-14 | 2015-11-12 | Mutant microorganisms resistant to lactose killing |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10858684B2 (zh) |
| EP (1) | EP3218509B1 (zh) |
| JP (2) | JP6765372B2 (zh) |
| KR (1) | KR102579346B1 (zh) |
| CN (2) | CN114015714A (zh) |
| AU (2) | AU2015345073B9 (zh) |
| BR (1) | BR112017006295B1 (zh) |
| CA (1) | CA2958786A1 (zh) |
| DK (1) | DK3218509T3 (zh) |
| RU (2) | RU2021109889A (zh) |
| SG (1) | SG11201701585VA (zh) |
| WO (1) | WO2016075243A1 (zh) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101731263B1 (ko) * | 2016-04-25 | 2017-05-02 | 서울대학교 산학협력단 | 코리네박테리움 글루타미쿰을 이용한 2'-푸코실락토오스의 생산방법 |
| EP3315610B1 (en) | 2016-10-29 | 2020-12-16 | Jennewein Biotechnologie GmbH | Process for the production of fucosylated oligosaccharides |
| KR20190098246A (ko) | 2016-12-27 | 2019-08-21 | 인바이오스 엔.브이. | 시알일화 화합물의 인 비보 합성 |
| MX2020007192A (es) * | 2017-12-01 | 2020-08-24 | Nestle Sa | Composicion fortificadora de leche humana. |
| US11913046B2 (en) | 2018-04-23 | 2024-02-27 | Inbiose N.V. | Increasing export of 2'fucosyllactose from microbial cells through the expression of a heterologous nucleic acid |
| US20210071134A1 (en) * | 2018-04-23 | 2021-03-11 | Dupont Nutrition Biosciences Aps | Increasing activity of 2'fucosyllactose transporters endogenous to microbial cells |
| US10519475B1 (en) * | 2018-11-21 | 2019-12-31 | Amyris, Inc. | Biosynthesis of compounds in yeast |
| US20220002773A1 (en) * | 2018-12-18 | 2022-01-06 | Inbiose N.V. | Production of 3-fucosyllactose and lactose converting alpha-1,3-fucosyltransferase enzymes |
| CN109735479B (zh) * | 2019-01-30 | 2022-04-01 | 光明乳业股份有限公司 | 一种合成2’-岩藻糖基乳糖的重组枯草芽孢杆菌及其构建方法与应用 |
| BR112022000394A2 (pt) | 2019-07-19 | 2022-03-03 | Inbiose Nv | Produção de fucosilactose em células hospedeiras |
| CN114829592A (zh) | 2019-12-17 | 2022-07-29 | 因比奥斯公司 | 转化乳糖的α-1,2-岩藻糖基转移酶 |
| US20230212628A1 (en) | 2019-12-18 | 2023-07-06 | Inbiose N.V. | Production of Sialylated Oligosaccharide in Host Cells |
| EP4103685A1 (en) | 2020-02-14 | 2022-12-21 | Inbiose N.V. | Glycominimized bacterial host cells |
| KR20220155298A (ko) | 2020-02-14 | 2022-11-22 | 인바이오스 엔.브이. | 숙주 세포에서 글리코실화 생성물의 생산 |
| EP3954769A1 (en) | 2020-08-10 | 2022-02-16 | Inbiose N.V. | Production of oligosaccharide mixtures by a cell |
| CN116171328A (zh) | 2020-08-10 | 2023-05-26 | 因比奥斯公司 | 藉由细胞培养或微生物发酵产生的不同寡糖的纯化混合物的制造方法 |
| EP4192973A2 (en) | 2020-08-10 | 2023-06-14 | Inbiose N.V. | Production of galactosylated di- and oligosaccharides |
| EP4192946A1 (en) | 2020-08-10 | 2023-06-14 | Inbiose N.V. | Cellular production of di- and/or oligosaccharides |
| TW202221130A (zh) | 2020-08-10 | 2022-06-01 | 比利時商因比奧斯公司 | 唾液酸化雙醣及/或寡醣的細胞生產 |
| CN116171329A (zh) | 2020-08-10 | 2023-05-26 | 因比奥斯公司 | 通过细胞培养或微生物发酵产生的寡糖溶液的纯化方法 |
| EP4263816A1 (en) | 2020-12-18 | 2023-10-25 | Inbiose N.V. | Variant sucrose permease polypeptides |
| EP4019534A1 (en) | 2020-12-22 | 2022-06-29 | Chr. Hansen HMO GmbH | Microbial cells possessing a reduced lactose internalization for producing an oligosaccharide |
| AU2022210808A1 (en) | 2021-01-20 | 2023-08-31 | Inbiose N.V. | Production of oligosaccharides comprising ln3 as core structure in host cells |
| CN117157394A (zh) | 2021-04-16 | 2023-12-01 | 因比奥斯公司 | 发酵生产 |
| WO2022219188A1 (en) | 2021-04-16 | 2022-10-20 | Inbiose N.V. | Cellular production of sialylated di- and/or oligosaccharides |
| CN117222736A (zh) | 2021-04-16 | 2023-12-12 | 因比奥斯公司 | 生物产物的细胞生产 |
| EP4370664A1 (en) | 2021-07-16 | 2024-05-22 | Inbiose N.V. | Lacto-n-biose converting fucosyltransferases |
| CN113881586B (zh) * | 2021-09-27 | 2023-03-10 | 四川大学 | 耐高温、耐高糖、耐高盐酿酒酵母菌株及构建方法和应用 |
| WO2023110995A1 (en) | 2021-12-14 | 2023-06-22 | Inbiose N.V. | Production of alpha-1,3-fucosylated compounds |
| WO2023110994A1 (en) | 2021-12-14 | 2023-06-22 | Inbiose N.V. | Production of alpha-1,4-fucosylated compounds |
| CN114645070B (zh) * | 2022-02-28 | 2022-12-20 | 北京焉支山科技有限公司 | 一种己糖-6-磷酸组合物的制备方法及其在化妆品中的应用 |
| WO2024017987A1 (en) | 2022-07-20 | 2024-01-25 | Inbiose N.V. | Production of oligosaccharides in host cells |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5858752A (en) | 1995-06-07 | 1999-01-12 | The General Hospital Corporation | Fucosyltransferase genes and uses thereof |
| MY148510A (en) * | 2006-03-09 | 2013-04-30 | Centre Nat Rech Scient | Method for producing sialylated oligosaccharides |
| US9453230B2 (en) | 2011-02-16 | 2016-09-27 | Glycosyn LLC | Biosynthesis of human milk oligosaccharides in engineered bacteria |
| CN103987841B (zh) * | 2011-12-16 | 2016-09-28 | 根特大学 | 用于合成可拉酸、甘露糖基化和/或岩藻糖基化寡糖的突变微生物 |
| CN102604849B (zh) * | 2012-03-23 | 2013-08-14 | 天津科技大学 | 一株高效利用乳糖生产燃料乙醇的酿酒酵母工程菌 |
-
2015
- 2015-11-12 CA CA2958786A patent/CA2958786A1/en active Pending
- 2015-11-12 BR BR112017006295-0A patent/BR112017006295B1/pt active IP Right Grant
- 2015-11-12 EP EP15797912.1A patent/EP3218509B1/en active Active
- 2015-11-12 KR KR1020177007250A patent/KR102579346B1/ko active IP Right Grant
- 2015-11-12 US US15/505,809 patent/US10858684B2/en active Active
- 2015-11-12 CN CN202111280441.8A patent/CN114015714A/zh active Pending
- 2015-11-12 DK DK15797912.1T patent/DK3218509T3/da active
- 2015-11-12 JP JP2017525844A patent/JP6765372B2/ja active Active
- 2015-11-12 RU RU2021109889A patent/RU2021109889A/ru unknown
- 2015-11-12 SG SG11201701585VA patent/SG11201701585VA/en unknown
- 2015-11-12 CN CN201580053480.0A patent/CN107075506B/zh active Active
- 2015-11-12 WO PCT/EP2015/076449 patent/WO2016075243A1/en active Application Filing
- 2015-11-12 RU RU2017120211A patent/RU2746410C2/ru active
- 2015-11-12 AU AU2015345073A patent/AU2015345073B9/en active Active
-
2020
- 2020-09-15 JP JP2020154738A patent/JP2021000116A/ja active Pending
- 2020-10-30 US US17/085,380 patent/US20210095321A1/en active Pending
-
2021
- 2021-06-17 AU AU2021204038A patent/AU2021204038B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP6765372B2 (ja) | 2020-10-07 |
| JP2017534292A (ja) | 2017-11-24 |
| EP3218509A1 (en) | 2017-09-20 |
| US20210095321A1 (en) | 2021-04-01 |
| CN107075506B (zh) | 2022-06-03 |
| KR20170076650A (ko) | 2017-07-04 |
| BR112017006295B1 (pt) | 2023-10-17 |
| RU2746410C2 (ru) | 2021-04-13 |
| AU2015345073B9 (en) | 2021-04-29 |
| AU2021204038B2 (en) | 2024-03-14 |
| AU2015345073B2 (en) | 2021-04-08 |
| KR102579346B1 (ko) | 2023-09-15 |
| AU2021204038A1 (en) | 2021-07-08 |
| CN107075506A (zh) | 2017-08-18 |
| US10858684B2 (en) | 2020-12-08 |
| CA2958786A1 (en) | 2016-05-19 |
| EP3218509B1 (en) | 2024-02-28 |
| RU2017120211A (ru) | 2018-12-14 |
| JP2021000116A (ja) | 2021-01-07 |
| BR112017006295A2 (pt) | 2017-12-12 |
| AU2015345073A1 (en) | 2017-03-23 |
| CN114015714A (zh) | 2022-02-08 |
| RU2021109889A (ru) | 2021-05-06 |
| DK3218509T3 (da) | 2024-05-21 |
| RU2017120211A3 (zh) | 2019-04-25 |
| US20180066294A1 (en) | 2018-03-08 |
| WO2016075243A1 (en) | 2016-05-19 |
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