SG11201606697YA - Implant comprising fgf-18 - Google Patents
Implant comprising fgf-18Info
- Publication number
- SG11201606697YA SG11201606697YA SG11201606697YA SG11201606697YA SG11201606697YA SG 11201606697Y A SG11201606697Y A SG 11201606697YA SG 11201606697Y A SG11201606697Y A SG 11201606697YA SG 11201606697Y A SG11201606697Y A SG 11201606697YA SG 11201606697Y A SG11201606697Y A SG 11201606697YA
- Authority
- SG
- Singapore
- Prior art keywords
- fgf
- implant
- Prior art date
Links
- 102000003977 fibroblast growth factor 18 Human genes 0.000 title 1
- 108090000370 fibroblast growth factor 18 Proteins 0.000 title 1
- 239000007943 implant Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/26—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physical Education & Sports Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Botany (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14000598 | 2014-02-20 | ||
PCT/EP2015/053645 WO2015124739A1 (en) | 2014-02-20 | 2015-02-20 | Implant comprising fgf-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201606697YA true SG11201606697YA (en) | 2016-09-29 |
Family
ID=50151086
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201606697YA SG11201606697YA (en) | 2014-02-20 | 2015-02-20 | Implant comprising fgf-18 |
Country Status (24)
Country | Link |
---|---|
US (1) | US10086112B2 (pl) |
EP (1) | EP3107592B1 (pl) |
JP (1) | JP6510547B2 (pl) |
KR (1) | KR102421950B1 (pl) |
CN (1) | CN106232154A (pl) |
AR (1) | AR099556A1 (pl) |
AU (1) | AU2015220785B2 (pl) |
BR (1) | BR112016018681B1 (pl) |
CA (1) | CA2938796C (pl) |
DK (1) | DK3107592T3 (pl) |
ES (1) | ES2698117T3 (pl) |
HR (1) | HRP20181573T1 (pl) |
IL (1) | IL247106B (pl) |
LT (1) | LT3107592T (pl) |
MX (1) | MX368946B (pl) |
NZ (1) | NZ723177A (pl) |
PL (1) | PL3107592T3 (pl) |
PT (1) | PT3107592T (pl) |
RS (1) | RS58138B1 (pl) |
RU (1) | RU2700414C2 (pl) |
SG (1) | SG11201606697YA (pl) |
SI (1) | SI3107592T1 (pl) |
WO (1) | WO2015124739A1 (pl) |
ZA (1) | ZA201605667B (pl) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2959509T3 (en) | 2013-02-14 | 2018-08-13 | Nanopareil Llc | Electrospun hybrid nanofiber felt, method of making it and method of purifying biomolecules |
NZ723148A (en) | 2014-02-20 | 2022-08-26 | Merck Patent Gmbh | Fgf-18 compound dosing regimen |
CN117187255B (zh) * | 2023-11-07 | 2024-01-30 | 北京大学第三医院(北京大学第三临床医学院) | 编码FGF18或rhFGF18的mRNA及其在骨关节炎治疗中的应用 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6511958B1 (en) * | 1997-08-14 | 2003-01-28 | Sulzer Biologics, Inc. | Compositions for regeneration and repair of cartilage lesions |
DE69714035T2 (de) * | 1997-08-14 | 2003-03-06 | Sulzer Innotec Ag, Winterthur | Zusammensetzung und Vorrichtung zur Reparatur von Knorpelgewebe in vivo bestehend aus Nanokapseln mit osteoinduktiven und/oder chondroinduktiven Faktoren |
KR100380119B1 (ko) * | 2001-04-19 | 2003-04-11 | 한국항공우주연구원 | 이원화된 통신속도 적응형 베이스 밴드 스위칭 위상시프트 키잉 장치 |
EP1273365A1 (fr) * | 2001-07-06 | 2003-01-08 | Recherche Et Developpement Du Groupe Cockerill Sambre | Outils rotatifs pour le perçage en ligne de produits profiles |
EP1551426B1 (en) * | 2002-10-07 | 2014-06-25 | ZymoGenetics, Inc. | Methods of administering fgf18 |
US8852240B2 (en) | 2004-10-25 | 2014-10-07 | Kieran Murphy, Llc | Methods and compositions for fostering and preserving bone growth |
DK1828239T3 (da) * | 2004-12-10 | 2011-12-19 | Zymogenetics Inc | FGF18-produktion i prokaryote værter |
SI2054050T1 (sl) * | 2006-08-25 | 2012-12-31 | Ares Trading S.A. | Zdravljenje hrustanäśnih obolenj z fgf-18 |
EP2403514A4 (en) | 2009-03-05 | 2012-11-14 | Biomimetic Therapeutics Inc | Platelet-derived growth factor compositions and methods of treating osteocartilaginous defects |
US8431399B2 (en) | 2010-03-02 | 2013-04-30 | Taipei Medical University | Method to restore cartilaginous phenotype of chondrocytes after cultured and expanded in vitro |
US10130687B2 (en) * | 2011-01-05 | 2018-11-20 | Rhode Island Hospital | Compositions and methods for the treatment of orthopedic disease or injury |
JP5990720B2 (ja) * | 2011-02-22 | 2016-09-14 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 骨再生及び/又は軟骨再生に使用するためのナノリザーバー技術 |
SG11201604972TA (en) * | 2013-12-24 | 2016-07-28 | Ares Trading Sa | Fgf-18 formulation in alginate/collagen hydrogels |
NZ723148A (en) | 2014-02-20 | 2022-08-26 | Merck Patent Gmbh | Fgf-18 compound dosing regimen |
CN106232153B (zh) | 2014-02-20 | 2020-01-17 | 默克专利有限公司 | 用于移植和组织工程手术的fgf-18 |
-
2015
- 2015-02-20 DK DK15706011.2T patent/DK3107592T3/en active
- 2015-02-20 SI SI201530409T patent/SI3107592T1/sl unknown
- 2015-02-20 RU RU2016137291A patent/RU2700414C2/ru active
- 2015-02-20 ES ES15706011T patent/ES2698117T3/es active Active
- 2015-02-20 US US15/120,137 patent/US10086112B2/en active Active
- 2015-02-20 PL PL15706011T patent/PL3107592T3/pl unknown
- 2015-02-20 KR KR1020167025247A patent/KR102421950B1/ko active IP Right Grant
- 2015-02-20 BR BR112016018681-8A patent/BR112016018681B1/pt active IP Right Grant
- 2015-02-20 WO PCT/EP2015/053645 patent/WO2015124739A1/en active Application Filing
- 2015-02-20 CN CN201580020527.3A patent/CN106232154A/zh active Pending
- 2015-02-20 NZ NZ723177A patent/NZ723177A/en unknown
- 2015-02-20 CA CA2938796A patent/CA2938796C/en active Active
- 2015-02-20 AU AU2015220785A patent/AU2015220785B2/en active Active
- 2015-02-20 MX MX2016010874A patent/MX368946B/es active IP Right Grant
- 2015-02-20 EP EP15706011.2A patent/EP3107592B1/en active Active
- 2015-02-20 JP JP2016553402A patent/JP6510547B2/ja active Active
- 2015-02-20 PT PT15706011T patent/PT3107592T/pt unknown
- 2015-02-20 LT LTEP15706011.2T patent/LT3107592T/lt unknown
- 2015-02-20 AR ARP150100505A patent/AR099556A1/es not_active Application Discontinuation
- 2015-02-20 SG SG11201606697YA patent/SG11201606697YA/en unknown
- 2015-02-20 RS RS20181404A patent/RS58138B1/sr unknown
-
2016
- 2016-08-04 IL IL247106A patent/IL247106B/en active IP Right Grant
- 2016-08-16 ZA ZA2016/05667A patent/ZA201605667B/en unknown
-
2018
- 2018-10-02 HR HRP20181573TT patent/HRP20181573T1/hr unknown
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