SG11201605721XA - Substituted bicyclic heteroaryl compounds as rxr agonists - Google Patents
Substituted bicyclic heteroaryl compounds as rxr agonistsInfo
- Publication number
- SG11201605721XA SG11201605721XA SG11201605721XA SG11201605721XA SG11201605721XA SG 11201605721X A SG11201605721X A SG 11201605721XA SG 11201605721X A SG11201605721X A SG 11201605721XA SG 11201605721X A SG11201605721X A SG 11201605721XA SG 11201605721X A SG11201605721X A SG 11201605721XA
- Authority
- SG
- Singapore
- Prior art keywords
- bicyclic heteroaryl
- substituted bicyclic
- heteroaryl compounds
- rxr agonists
- rxr
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
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- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/16—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
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- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
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- C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
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- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/66—Nitrogen atoms not forming part of a nitro radical
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- C07D333/72—Benzo[c]thiophenes; Hydrogenated benzo[c]thiophenes
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- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- General Health & Medical Sciences (AREA)
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN161CH2014 | 2014-01-14 | ||
PCT/IN2015/000010 WO2015107549A1 (en) | 2014-01-14 | 2015-01-09 | Substituted bicyclic heteroaryl compounds as rxr agonists |
Publications (1)
Publication Number | Publication Date |
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SG11201605721XA true SG11201605721XA (en) | 2016-08-30 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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SG11201605721XA SG11201605721XA (en) | 2014-01-14 | 2015-01-09 | Substituted bicyclic heteroaryl compounds as rxr agonists |
Country Status (21)
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US (1) | US9862713B2 (ru) |
EP (1) | EP3094626B1 (ru) |
JP (1) | JP6625057B2 (ru) |
KR (1) | KR102372599B1 (ru) |
CN (1) | CN107074800B (ru) |
AU (1) | AU2015207690B2 (ru) |
BR (1) | BR112016016348B1 (ru) |
CA (1) | CA2936162C (ru) |
CL (1) | CL2016001803A1 (ru) |
DK (1) | DK3094626T3 (ru) |
ES (1) | ES2795660T3 (ru) |
MA (1) | MA39253B1 (ru) |
MX (1) | MX2016009219A (ru) |
MY (1) | MY192609A (ru) |
PH (1) | PH12016501393B1 (ru) |
PL (1) | PL3094626T3 (ru) |
PT (1) | PT3094626T (ru) |
RU (1) | RU2721283C2 (ru) |
SG (1) | SG11201605721XA (ru) |
WO (1) | WO2015107549A1 (ru) |
ZA (1) | ZA201605102B (ru) |
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CN106565761A (zh) * | 2016-11-15 | 2017-04-19 | 贵州大学 | 一种4‑羧基苯硼酸的制备工艺 |
CN112047901B (zh) * | 2020-09-21 | 2023-01-24 | 自然资源部第三海洋研究所 | 苯并噻唑杂萜类化合物及其衍生物以及制备方法与应用 |
US11912676B1 (en) | 2023-08-29 | 2024-02-27 | King Faisal University | N'-[(4-chlorobenzoyl)oxy]-1,3-benzothiazole-2-carboximidamide as an antitumor and antimicrobial compound |
US11919873B1 (en) | 2023-08-29 | 2024-03-05 | King Faisal University | 1,3-benzothiazol-2-yl-N′-(benzoyloxy)ethanimidamide as an antitumor and antimicrobial compound |
US11851413B1 (en) | 2023-08-29 | 2023-12-26 | King Faisal University | 1,3-benzothiazol-2-yl-N'-[(naphthalene-1-carbonyl)oxy]ethanimidamide as an antitumor and antimicrobial compound |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
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DK158947C (da) | 1982-07-06 | 1991-01-21 | Hoffmann La Roche | Tetrahydronaphthalin-,benzofuran- og benzothiophenderivater, fremstilling og anvendelse deraf samt rodenticid indeholdende saadanne derivater |
GR78888B (ru) * | 1982-07-06 | 1984-10-02 | Hoffmann La Roche | |
US5420145A (en) * | 1993-03-22 | 1995-05-30 | Koichi Shudo | Carboxylic acid derivative |
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2015
- 2015-01-09 SG SG11201605721XA patent/SG11201605721XA/en unknown
- 2015-01-09 JP JP2016547014A patent/JP6625057B2/ja active Active
- 2015-01-09 MA MA39253A patent/MA39253B1/fr unknown
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- 2015-01-09 PL PL15714964T patent/PL3094626T3/pl unknown
- 2015-01-09 CN CN201580014389.8A patent/CN107074800B/zh active Active
- 2015-01-09 ES ES15714964T patent/ES2795660T3/es active Active
- 2015-01-09 WO PCT/IN2015/000010 patent/WO2015107549A1/en active Application Filing
- 2015-01-09 CA CA2936162A patent/CA2936162C/en active Active
- 2015-01-09 PT PT157149642T patent/PT3094626T/pt unknown
- 2015-01-09 AU AU2015207690A patent/AU2015207690B2/en not_active Ceased
- 2015-01-09 US US15/111,585 patent/US9862713B2/en active Active
- 2015-01-09 BR BR112016016348-6A patent/BR112016016348B1/pt active IP Right Grant
- 2015-01-09 DK DK15714964.2T patent/DK3094626T3/da active
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- 2015-01-09 RU RU2016128529A patent/RU2721283C2/ru active
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- 2015-01-09 KR KR1020167022235A patent/KR102372599B1/ko active IP Right Grant
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2016
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RU2016128529A3 (ru) | 2018-08-28 |
US20160333004A1 (en) | 2016-11-17 |
AU2015207690B2 (en) | 2018-09-27 |
RU2016128529A (ru) | 2018-02-20 |
DK3094626T3 (da) | 2020-05-25 |
BR112016016348B1 (pt) | 2022-10-18 |
RU2721283C2 (ru) | 2020-05-18 |
KR102372599B1 (ko) | 2022-03-10 |
PL3094626T3 (pl) | 2020-07-13 |
ES2795660T3 (es) | 2020-11-24 |
CA2936162C (en) | 2023-10-17 |
JP6625057B2 (ja) | 2019-12-25 |
EP3094626A1 (en) | 2016-11-23 |
CL2016001803A1 (es) | 2017-03-17 |
MA39253B1 (fr) | 2018-09-28 |
CN107074800B (zh) | 2019-11-12 |
EP3094626B1 (en) | 2020-02-19 |
PH12016501393A1 (en) | 2017-02-06 |
US9862713B2 (en) | 2018-01-09 |
MA39253A1 (fr) | 2018-06-29 |
CN107074800A (zh) | 2017-08-18 |
KR20160125958A (ko) | 2016-11-01 |
WO2015107549A1 (en) | 2015-07-23 |
PH12016501393B1 (en) | 2017-02-06 |
MY192609A (en) | 2022-08-29 |
BR112016016348A2 (ru) | 2017-08-08 |
AU2015207690A1 (en) | 2016-09-01 |
ZA201605102B (en) | 2017-07-26 |
JP2017502999A (ja) | 2017-01-26 |
CA2936162A1 (en) | 2015-07-23 |
PT3094626T (pt) | 2020-05-22 |
MX2016009219A (es) | 2017-03-06 |
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