SG11201604729QA - Delayed release compositions of linaclotide - Google Patents
Delayed release compositions of linaclotideInfo
- Publication number
- SG11201604729QA SG11201604729QA SG11201604729QA SG11201604729QA SG11201604729QA SG 11201604729Q A SG11201604729Q A SG 11201604729QA SG 11201604729Q A SG11201604729Q A SG 11201604729QA SG 11201604729Q A SG11201604729Q A SG 11201604729QA SG 11201604729Q A SG11201604729Q A SG 11201604729QA
- Authority
- SG
- Singapore
- Prior art keywords
- linaclotide
- delayed release
- release compositions
- compositions
- delayed
- Prior art date
Links
- 230000003111 delayed effect Effects 0.000 title 1
- KXGCNMMJRFDFNR-WDRJZQOASA-N linaclotide Chemical group C([C@H](NC(=O)[C@@H]1CSSC[C@H]2C(=O)N[C@H]3CSSC[C@H](N)C(=O)N[C@H](C(N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N2)=O)CSSC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(N)=O)NC3=O)C(=O)N[C@H](C(NCC(=O)N1)=O)[C@H](O)C)C(O)=O)C1=CC=C(O)C=C1 KXGCNMMJRFDFNR-WDRJZQOASA-N 0.000 title 1
- 229960000812 linaclotide Drugs 0.000 title 1
- 108010024409 linaclotide Proteins 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
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- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
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- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Nutrition Science (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361914952P | 2013-12-11 | 2013-12-11 | |
| US201361914951P | 2013-12-11 | 2013-12-11 | |
| PCT/US2014/069838 WO2015089326A1 (en) | 2013-12-11 | 2014-12-11 | Delayed release compositions of linaclotide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201604729QA true SG11201604729QA (en) | 2016-07-28 |
Family
ID=52293217
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201604729QA SG11201604729QA (en) | 2013-12-11 | 2014-12-11 | Delayed release compositions of linaclotide |
| SG10201804817TA SG10201804817TA (en) | 2013-12-11 | 2014-12-11 | Delayed release compositions of linaclotide |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201804817TA SG10201804817TA (en) | 2013-12-11 | 2014-12-11 | Delayed release compositions of linaclotide |
Country Status (29)
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA119335C2 (uk) * | 2013-12-11 | 2019-06-10 | Айронвуд Фармасьютикалз, Інк. | Композиції лінаклотиду з затриманим вивільненням |
| AR101476A1 (es) | 2014-08-07 | 2016-12-21 | Acerta Pharma Bv | Métodos para tratar cánceres, enfermedades inmunes y autoinmunes, y enfermedades inflamatorias en base a la tasa de ocupación de la tirosin quinasa de bruton (btk) y a la tasa de resíntesis de la tirosin quinasa de bruton (btk) |
| CA2902911C (en) | 2014-10-31 | 2017-06-27 | Purdue Pharma | Methods and compositions particularly for treatment of attention deficit disorder |
| US20180008547A1 (en) * | 2015-02-02 | 2018-01-11 | Aurobindo Pharma Ltd | Stable Compositions comprising Linaclotide |
| EP3302440B1 (en) * | 2015-06-05 | 2021-01-06 | Ironwood Pharmaceuticals, Inc. | Modified or targeted release formulations of linaclotide |
| US10588864B2 (en) | 2016-03-11 | 2020-03-17 | Gateway Pharmaceuticals LLC | Pharmaceutical compositions for colon-specific delivery |
| WO2017156214A1 (en) * | 2016-03-11 | 2017-09-14 | Gateway Pharmaceutical LLC | Pharmaceutical compositions for colon-specific delivery |
| US11534404B2 (en) * | 2016-10-06 | 2022-12-27 | Sucampo Ag | Multilayer beads for pharmaceutical use |
| WO2018119191A1 (en) * | 2016-12-21 | 2018-06-28 | Ironwood Pharmaceuticals Inc. | Methods of treating irritable bowel syndrome with modified or delayed release formulations of linaclotide |
| KR102227486B1 (ko) * | 2017-06-30 | 2021-03-12 | 롯데정밀화학 주식회사 | 프로톤 펌프 저해제를 포함하는 경구용 고형제제 조성물, 이를 포함하는 경구용 고형제제 및 그 제조방법 |
| MX2020009900A (es) * | 2018-03-23 | 2021-01-08 | Palatin Technologies Inc | Formulaciones peptidicas especificas para el receptor de melanocortinas y metodos para un suministro especifico en el tubo gastrointestinal. |
| US10722473B2 (en) | 2018-11-19 | 2020-07-28 | Purdue Pharma L.P. | Methods and compositions particularly for treatment of attention deficit disorder |
| EP3979992A4 (en) * | 2019-06-10 | 2023-09-13 | Ironwood Pharmaceuticals, Inc. | TREATMENT OF ABDOMINAL PAIN ASSOCIATED WITH DIARRHEA-DOMINANT IRGITABLE BOWEL SYSTEM |
| KR102104507B1 (ko) * | 2019-08-23 | 2020-04-24 | 브릿지바이오테라퓨틱스(주) | 팔미토일-l-프롤릴-l-프롤릴-글리실-l-타이로신 나트륨을 포함하는 약제학적 제제 및 이의 제조방법 |
| CN110935007B (zh) * | 2019-12-12 | 2023-06-23 | 烟台大学 | 利那洛肽复方组合物、制剂及其用途和制备方法 |
| GB202017863D0 (en) * | 2020-11-12 | 2020-12-30 | Intract Pharma Ltd | Novel compositions |
| WO2022245650A1 (en) * | 2021-05-19 | 2022-11-24 | Alberto Paz | Orally administered compositions for cancer treatment |
| TW202426473A (zh) * | 2022-10-03 | 2024-07-01 | 全福生物科技股份有限公司 | 包含pedf衍生短肽(pdsp)之組合物及其用途 |
| TW202440065A (zh) * | 2022-12-28 | 2024-10-16 | 日商中外製藥股份有限公司 | 包含分散對象物質的固體分散體、包含其之醫藥組合物及其製造方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7304036B2 (en) | 2003-01-28 | 2007-12-04 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US7371727B2 (en) | 2003-01-28 | 2008-05-13 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| CN201252259Y (zh) * | 2008-07-24 | 2009-06-03 | 富士康(昆山)电脑接插件有限公司 | 电连接器 |
| PT2328601T (pt) | 2008-08-15 | 2020-04-30 | Ironwood Pharmaceuticals Inc | Formulação sólida estável de um polipéptido agonista do recetor gc-c adequado para administração oral |
| EP2373296B1 (en) * | 2008-12-03 | 2016-08-03 | Synergy Pharmaceuticals Inc. | Formulations of guanylate cyclase c agonists and methods of use |
| US20130012454A1 (en) * | 2009-07-06 | 2013-01-10 | Ironwood Pharmaceuticals, Inc. | Orally Disintegrating Compositions of Linaclotide |
| CA2770077A1 (en) * | 2009-08-06 | 2011-02-10 | Ironwood Pharmaceuticals, Inc. | Formulations comprising linaclotide |
| MX2012001691A (es) * | 2009-08-12 | 2012-02-29 | Forest Lab Holdings Ltd | Composiciones de linaclotida que se desintegran oralmente. |
| RU2012109415A (ru) * | 2009-08-13 | 2013-09-20 | Айронвуд Фармасьютикалз, Инк. | Способ модуляции фармакодинамического эффекта перорально вводимых агонистов рецептора гуанилатциклазы |
| PL2536742T3 (pl) * | 2010-02-17 | 2017-11-30 | Ironwood Pharmaceuticals, Inc. | Leczenie zaburzeń żołądkowo-jelitowych |
| DK2603232T3 (da) * | 2010-08-11 | 2019-12-09 | Ironwood Pharmaceuticals Inc | Stabile formuleringer af linaclotid |
| MX2013002747A (es) * | 2010-09-11 | 2013-10-25 | Ironwood Pharmaceuticals Inc | Tratamiento del sindrome de intestino irritable predominante con estreñimiento. |
| JP2012155108A (ja) * | 2011-01-26 | 2012-08-16 | Kyocera Document Solutions Inc | 現像ローラ、現像装置および画像形成装置 |
| PL2776055T3 (pl) * | 2011-08-17 | 2017-06-30 | Ironwood Pharmaceuticals, Inc. | Sposoby leczenia zaburzeń żołądkowo-jelitowych |
| JP5553132B2 (ja) * | 2011-09-30 | 2014-07-16 | アステラス製薬株式会社 | 粒子状医薬組成物 |
| JP2016521249A (ja) * | 2012-07-12 | 2016-07-21 | フォレスト ラボラトリーズ ホールディングス リミテッド | リナクロチド組成物 |
| HK1218629A1 (zh) * | 2013-02-25 | 2017-03-03 | Bausch Health Ireland Limited | 用於结肠清洁的鸟苷酸环化酶受体激动剂 |
| UA119335C2 (uk) * | 2013-12-11 | 2019-06-10 | Айронвуд Фармасьютикалз, Інк. | Композиції лінаклотиду з затриманим вивільненням |
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2014
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2016
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2017
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2019
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2022
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2023
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