SG11201506876XA - Modification of polypeptides - Google Patents
Modification of polypeptidesInfo
- Publication number
- SG11201506876XA SG11201506876XA SG11201506876XA SG11201506876XA SG11201506876XA SG 11201506876X A SG11201506876X A SG 11201506876XA SG 11201506876X A SG11201506876X A SG 11201506876XA SG 11201506876X A SG11201506876X A SG 11201506876XA SG 11201506876X A SG11201506876X A SG 11201506876XA
- Authority
- SG
- Singapore
- Prior art keywords
- polypeptides
- modification
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/832,526 US20140274759A1 (en) | 2013-03-15 | 2013-03-15 | Modification of polypeptides |
PCT/EP2014/055204 WO2014140342A1 (en) | 2013-03-15 | 2014-03-14 | Modification of polypeptides |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201506876XA true SG11201506876XA (en) | 2015-09-29 |
Family
ID=50288071
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201506876XA SG11201506876XA (en) | 2013-03-15 | 2014-03-14 | Modification of polypeptides |
Country Status (12)
Country | Link |
---|---|
US (2) | US20140274759A1 (pt) |
EP (1) | EP2970954B1 (pt) |
JP (1) | JP6437468B2 (pt) |
CN (1) | CN105189747B (pt) |
AU (1) | AU2014229994B2 (pt) |
CA (1) | CA2901535C (pt) |
DK (1) | DK2970954T3 (pt) |
ES (1) | ES2700999T3 (pt) |
PL (1) | PL2970954T3 (pt) |
PT (1) | PT2970954T (pt) |
SG (1) | SG11201506876XA (pt) |
WO (1) | WO2014140342A1 (pt) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LT3299377T (lt) | 2011-10-07 | 2021-03-25 | Bicyclerd Limited | Struktūrizuoto polipeptido specifiškumo moduliavimas |
GB201306623D0 (en) | 2013-04-11 | 2013-05-29 | Bicycle Therapeutics Ltd | Modulation of structured polypeptide specificity |
ES2715379T3 (es) * | 2013-10-28 | 2019-06-04 | Bicyclerd Ltd | Novedosos polipéptidos |
CA2965754C (en) | 2014-10-29 | 2024-01-02 | Bicycle Therapeutics Limited | Bicyclic peptide ligands specific for mt1-mmp |
GB201607827D0 (en) | 2016-05-04 | 2016-06-15 | Bicycle Therapeutics Ltd | Bicyclic peptide-toxin conjugates specific for MT1-MMP |
CN110603261A (zh) | 2016-12-23 | 2019-12-20 | 拜斯科阿迪有限公司 | 具有新型键结构的肽衍生物 |
GB201706477D0 (en) | 2017-04-24 | 2017-06-07 | Bicycle Therapeutics Ltd | Modification of polypeptides |
CN111032678A (zh) | 2017-06-26 | 2020-04-17 | 拜西克尔德有限公司 | 具有可检测部分的双环肽配体和其用途 |
CN111183147A (zh) * | 2017-08-04 | 2020-05-19 | 拜斯科技术开发有限公司 | Cd137特异性的双环肽配体 |
WO2019084060A1 (en) | 2017-10-24 | 2019-05-02 | Silverback Therapeutics, Inc. | CONJUGATES AND METHODS OF USE FOR THE SELECTIVE DELIVERY OF IMMUNOMODULATORY AGENTS |
TWI825046B (zh) | 2017-12-19 | 2023-12-11 | 英商拜西可泰克斯有限公司 | Epha2特用之雙環胜肽配位基 |
GB201721265D0 (en) | 2017-12-19 | 2018-01-31 | Bicyclerd Ltd | Bicyclic peptide ligands specific for EphA2 |
CN112236442A (zh) * | 2018-04-04 | 2021-01-15 | 拜斯科技术开发有限公司 | 异源串联双环肽复合物 |
KR20210013560A (ko) * | 2018-04-19 | 2021-02-04 | 스티칭 브이유 | 단백질 거대고리화 |
US11180531B2 (en) * | 2018-06-22 | 2021-11-23 | Bicycletx Limited | Bicyclic peptide ligands specific for Nectin-4 |
GB201810320D0 (en) * | 2018-06-22 | 2018-08-08 | Bicycletx Ltd | Peptide ligands for binding to CD38 |
GB201810329D0 (en) * | 2018-06-22 | 2018-08-08 | Bicycletx Ltd | Peptide ligands for binding to integrin avB3 |
GB201810316D0 (en) | 2018-06-22 | 2018-08-08 | Bicyclerd Ltd | Peptide ligands for binding to EphA2 |
US20200113912A1 (en) | 2018-09-12 | 2020-04-16 | Silverback Therapeutics, Inc. | Methods and Compositions for the Treatment of Disease with Immune Stimulatory Conjugates |
CA3112545A1 (en) | 2018-09-12 | 2020-03-19 | Silverback Therapeutics, Inc. | Substituted benzazepine compounds, conjugates, and uses thereof |
WO2020128526A1 (en) * | 2018-12-21 | 2020-06-25 | Bicycletx Limited | Bicyclic peptide ligands specific for pd-l1 |
GB201900529D0 (en) * | 2019-01-15 | 2019-03-06 | Bicycletx Ltd | Bicyclic peptide ligands specific for CD38 |
TW202110485A (zh) | 2019-07-30 | 2021-03-16 | 英商拜西可泰克斯有限公司 | 異質雙環肽複合物 |
EP4013456A1 (en) | 2019-08-15 | 2022-06-22 | Silverback Therapeutics, Inc. | Formulations of benzazepine conjugates and uses thereof |
GB201914233D0 (en) | 2019-10-02 | 2019-11-13 | Bicyclerd Ltd | Phage cyclisation assay |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0913775D0 (en) | 2009-08-06 | 2009-09-16 | Medical Res Council | Multispecific peptides |
-
2013
- 2013-03-15 US US13/832,526 patent/US20140274759A1/en not_active Abandoned
-
2014
- 2014-03-14 PT PT14710558T patent/PT2970954T/pt unknown
- 2014-03-14 DK DK14710558.9T patent/DK2970954T3/da active
- 2014-03-14 SG SG11201506876XA patent/SG11201506876XA/en unknown
- 2014-03-14 CN CN201480014384.0A patent/CN105189747B/zh active Active
- 2014-03-14 EP EP14710558.9A patent/EP2970954B1/en active Active
- 2014-03-14 PL PL14710558T patent/PL2970954T3/pl unknown
- 2014-03-14 ES ES14710558T patent/ES2700999T3/es active Active
- 2014-03-14 JP JP2015562247A patent/JP6437468B2/ja active Active
- 2014-03-14 WO PCT/EP2014/055204 patent/WO2014140342A1/en active Application Filing
- 2014-03-14 CA CA2901535A patent/CA2901535C/en active Active
- 2014-03-14 AU AU2014229994A patent/AU2014229994B2/en active Active
-
2015
- 2015-09-10 US US14/849,637 patent/US9932367B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
PL2970954T3 (pl) | 2019-04-30 |
JP2016527180A (ja) | 2016-09-08 |
DK2970954T3 (da) | 2019-01-02 |
JP6437468B2 (ja) | 2018-12-12 |
CA2901535A1 (en) | 2014-09-18 |
CA2901535C (en) | 2021-06-22 |
AU2014229994A1 (en) | 2015-09-17 |
EP2970954B1 (en) | 2018-10-24 |
CN105189747A (zh) | 2015-12-23 |
EP2970954A1 (en) | 2016-01-20 |
WO2014140342A1 (en) | 2014-09-18 |
US20160031939A1 (en) | 2016-02-04 |
PT2970954T (pt) | 2018-12-17 |
AU2014229994B2 (en) | 2020-03-05 |
CN105189747B (zh) | 2019-03-08 |
ES2700999T3 (es) | 2019-02-20 |
US20140274759A1 (en) | 2014-09-18 |
US9932367B2 (en) | 2018-04-03 |
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