SG11201504097PA - Assays for detecting neutralizing autoantibodies to biologic therapy - Google Patents

Assays for detecting neutralizing autoantibodies to biologic therapy

Info

Publication number
SG11201504097PA
SG11201504097PA SG11201504097PA SG11201504097PA SG11201504097PA SG 11201504097P A SG11201504097P A SG 11201504097PA SG 11201504097P A SG11201504097P A SG 11201504097PA SG 11201504097P A SG11201504097P A SG 11201504097PA SG 11201504097P A SG11201504097P A SG 11201504097PA
Authority
SG
Singapore
Prior art keywords
assays
biologic therapy
detecting neutralizing
neutralizing autoantibodies
autoantibodies
Prior art date
Application number
SG11201504097PA
Other languages
English (en)
Inventor
Scott Hauenstein
Sharat Singh
Original Assignee
Nestec Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/802,117 external-priority patent/US20130266963A1/en
Application filed by Nestec Sa filed Critical Nestec Sa
Publication of SG11201504097PA publication Critical patent/SG11201504097PA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52Assays involving cytokines
    • G01N2333/525Tumor necrosis factor [TNF]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SG11201504097PA 2012-11-30 2013-11-27 Assays for detecting neutralizing autoantibodies to biologic therapy SG11201504097PA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261732251P 2012-11-30 2012-11-30
US13/802,117 US20130266963A1 (en) 2011-07-06 2013-03-13 Assay for detecting neutralizing autoantibodies to biologic therapy
PCT/IB2013/060458 WO2014083520A2 (fr) 2012-11-30 2013-11-27 Dosages pour la détection d'auto-anticorps de neutralisation à une thérapie biologique

Publications (1)

Publication Number Publication Date
SG11201504097PA true SG11201504097PA (en) 2015-06-29

Family

ID=50828561

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201504097PA SG11201504097PA (en) 2012-11-30 2013-11-27 Assays for detecting neutralizing autoantibodies to biologic therapy
SG10201703210XA SG10201703210XA (en) 2012-11-30 2013-11-27 Assays for detecting neutralizing autoantibodies to biologic therapy

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201703210XA SG10201703210XA (en) 2012-11-30 2013-11-27 Assays for detecting neutralizing autoantibodies to biologic therapy

Country Status (13)

Country Link
EP (1) EP2926136A2 (fr)
JP (1) JP2016502091A (fr)
KR (1) KR20150088890A (fr)
CN (1) CN105074461A (fr)
AU (1) AU2013350817A1 (fr)
BR (1) BR112015012482A2 (fr)
CA (1) CA2892766A1 (fr)
HK (1) HK1215969A1 (fr)
IL (1) IL238995A0 (fr)
MX (1) MX2015006852A (fr)
RU (1) RU2015125739A (fr)
SG (2) SG11201504097PA (fr)
WO (1) WO2014083520A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX343328B (es) 2009-10-26 2016-11-01 Nestec Sa Analisis para la deteccion de farmacos anti-tnf y anticuerpos.
BR112013009376A2 (pt) 2010-10-18 2016-07-26 Nestec Sa métodos para determinar isótipos de anticorpos antifármacos
SG10201605516YA (en) 2011-07-06 2016-08-30 Nestec Sa Assays for detecting neutralizing autoantibodies to biologic therapy with tnf alpha
SG11201704200SA (en) 2014-12-05 2017-06-29 Nestec Sa Indirect homogeneous mobility shift assays for the detection of biologics in patient samples
WO2016110595A1 (fr) 2015-01-09 2016-07-14 Atonomics A/S Test universel pour déterminer la quantité de médicaments inhibiteurs de tnfα et leurs anticorps anti-médicament correspondants
US11119096B2 (en) 2016-07-08 2021-09-14 W. Health L.P. Universal assay for determining the quantity of therapeutic monoclonal antibodies and their corresponding anti-drug-antibodies in samples
SG11201908154RA (en) * 2017-03-31 2019-10-30 Ablynx Nv Improved immunogenicity assays
CN111024958B (zh) * 2020-03-11 2020-06-23 同昕生物技术(北京)有限公司 用于检测单抗药物和抗单抗药物抗体的试剂及其应用
CN112730846B (zh) * 2020-12-18 2023-12-15 安渡生物医药(杭州)有限公司 一种用于小鼠血样检测免疫复合物的方法
CN114047343B (zh) * 2022-01-13 2022-05-31 美迪西普亚医药科技(上海)有限公司 双耐受型抗IgE单抗药物的免疫原性分析试剂盒及其使用方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX343328B (es) * 2009-10-26 2016-11-01 Nestec Sa Analisis para la deteccion de farmacos anti-tnf y anticuerpos.
EP2564202B1 (fr) * 2010-04-29 2015-07-01 Theradiag SA Détection d'anticorps dirigés contre des anticorps thérapeutiques
BR112013009376A2 (pt) * 2010-10-18 2016-07-26 Nestec Sa métodos para determinar isótipos de anticorpos antifármacos
ES2530175T3 (es) * 2011-02-17 2015-02-26 Nestec S.A. Ensayos para la detección de autoanticuerpos contra fármacos anti-TNF
SG10201605516YA (en) * 2011-07-06 2016-08-30 Nestec Sa Assays for detecting neutralizing autoantibodies to biologic therapy with tnf alpha

Also Published As

Publication number Publication date
HK1215969A1 (zh) 2016-09-30
AU2013350817A1 (en) 2015-06-11
RU2015125739A (ru) 2017-01-13
SG10201703210XA (en) 2017-06-29
IL238995A0 (en) 2015-07-30
CA2892766A1 (fr) 2014-06-05
JP2016502091A (ja) 2016-01-21
BR112015012482A2 (pt) 2017-07-11
EP2926136A2 (fr) 2015-10-07
WO2014083520A3 (fr) 2014-07-31
MX2015006852A (es) 2015-09-16
WO2014083520A2 (fr) 2014-06-05
CN105074461A (zh) 2015-11-18
KR20150088890A (ko) 2015-08-03

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