SG11201406848TA - Fluorescence imaging system for an operating theatre - Google Patents

Fluorescence imaging system for an operating theatre

Info

Publication number
SG11201406848TA
SG11201406848TA SG11201406848TA SG11201406848TA SG11201406848TA SG 11201406848T A SG11201406848T A SG 11201406848TA SG 11201406848T A SG11201406848T A SG 11201406848TA SG 11201406848T A SG11201406848T A SG 11201406848TA SG 11201406848T A SG11201406848T A SG 11201406848TA
Authority
SG
Singapore
Prior art keywords
attenuation
fluorescence
lllll
internationale
emission
Prior art date
Application number
SG11201406848TA
Inventor
Philippe Rizo
Norman Mangeret
Original Assignee
Fluoptics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fluoptics filed Critical Fluoptics
Publication of SG11201406848TA publication Critical patent/SG11201406848TA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A61B90/361—Image-producing devices, e.g. surgical cameras
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/30—Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure
    • A61B2090/309—Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure using white LEDs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3937—Visible markers
    • A61B2090/3941—Photoluminescent markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3937—Visible markers
    • A61B2090/395—Visible markers with marking agent for marking skin or other tissue
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F21—LIGHTING
    • F21W—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES F21K, F21L, F21S and F21V, RELATING TO USES OR APPLICATIONS OF LIGHTING DEVICES OR SYSTEMS
    • F21W2131/00—Use or application of lighting devices or systems not provided for in codes F21W2102/00-F21W2121/00
    • F21W2131/20—Lighting for medical use
    • F21W2131/205—Lighting for medical use for operating theatres
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics
    • G01N2021/6471—Special filters, filter wheel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/062—LED's

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biophysics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

(12) DEMANDE INTERNATIONALE PUBLIEE EN VERTU DU TRAITE DE COOPERATION EN MATIERE DE BREVETS (PCT) (19) Organisation Mondiale de la Propriete Intellectuelle Bureau international —- (I®) Numero de publication internationale (43) Date de la publication internationale ^ _ WO 2013/160279 A1 31 octobre 2013 (31.10.2013) WIPO I PCT (51) Classification internationale des brevets : A61B 5/00 (2006.01) A61B 19/00 (2006.01) (21) Numero de la demande internationale : PCT/EP2013/058352 (22) Date de depot international: (25) Langue de depot: (26) Langue de publication : 23 avril 2013 (23.04.2013) frarujais frarujais (30) Donnees relatives a la priorite : 1253786 25 avril 2012 (25.04.2012) FR (71) Deposant : FLUOPTICS [FR/FR]; 7, Parvis Louis Neel, F-38040 Grenoble (FR). (72) Inventeurs RIZO, Philippe; : 25, chemin de Chantemerle, F-38700 La Tranche (FR). MANGERET, Norman; 534, montee de la Creuse, F-38560 Jarrie (FR). (74) Mandataire : REGIMBEAU; 139, rue Vendome, F- 69477 Lyon Cedex 06 (FR). (81) Etats designes (sauf indication contraire, pour tout titre de protection nationale disponible) : AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Etats designes (sauf indication contraire, pour tout titre de protection regionale disponible) : ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), eurasien (AM, AZ, BY, KG, KZ, RU, TJ, TM), europeen (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Declarations en vertu de la regie 4.17 : — relative a la qualite d'inventeur (regie 4.17.iv)) Publiee : — avec rapport de recherche internationale (Art. 21(3)) (54) Title : FLUORESCENCE IMAGING SYSTEM FOR AN OPERATING THEATRE (54) Titre : SYSTEME D'IMAGERIE DE FLUORESCENCE POUR UN BLOC OPERATOIRE FIG. 3 0\ l> CJ o i-H cn i-H o CJ o & (57) Abstract : Fluorescence imaging system for an operating theatre, comprising device illuminating a the operating theatre and emitting a white light, and fluorescence a imaging device. Said fluorescence imaging device comprises a light source emitting radia­ tion for excitation of fluorescent a marker in a range of emission wavelengths of between 600 and 900 nm. The light emitted by the illuminating device is filtered by a low-pass filter, of which the cut-off wavelength is below the emission range of the fluorescent marker, but is nonetheless able to show an increase or fluctuations in the attenuation for wavelengths above the emission range of the fluorescent marker, the product of the attenuation of the filter of the detector and of the attenuation of the low-pass filter of the illuminating device leading an attenuation to by a factor of at least 10 . 6 (57) Abrege : [Suite sur la page suivante] WO 2013/160279 A11 lllll llllllll II llllll III lllll lllll III III III lllll lllll lllll llll llll lllll lllll lllllll llll llll Systeme d'imagerie de fluorescence pour un bloc operatoire comprenant un dispositif d'eclairage de bloc operatoire emettant une lumiere blanche et un dispositif d'imagerie de fluorescence. Ledit dispositif d'imagerie de fluorescence comprend une source lumi- neuse emettant un rayonnement d'excitation d'un marqueur fluorescent dans une gamme de longueurs d'onde d'emission comprise entre 600 et 900 nm, La lumiere emise par le dispositif d'eclairage est filtree par un filtre passe bas dont la longueur d'onde de coupure est inferieure a la gamme d'emission du marqueur fluorescent, mais pouvant neanmoins presenter une remontee ou des fluctuations de I'attenuation pour des longueurs d'onde superieures a la gamme d'emission du marqueur fluorescent, le produit de I'attenuation du filtre du detecteur et de I'attenuation du filtre passe-bas du dispositif d'eclairage conduisant a une attenuation par un facteur d'au moins 10 . 6
SG11201406848TA 2012-04-25 2013-04-23 Fluorescence imaging system for an operating theatre SG11201406848TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1253786A FR2989876B1 (en) 2012-04-25 2012-04-25 FLUORESCENCE IMAGING SYSTEM FOR AN OPERATIVE BLOCK
PCT/EP2013/058352 WO2013160279A1 (en) 2012-04-25 2013-04-23 Fluorescence imaging system for an operating theatre

Publications (1)

Publication Number Publication Date
SG11201406848TA true SG11201406848TA (en) 2015-01-29

Family

ID=48142809

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201406848TA SG11201406848TA (en) 2012-04-25 2013-04-23 Fluorescence imaging system for an operating theatre

Country Status (8)

Country Link
US (2) US20150083932A1 (en)
EP (1) EP2840953B1 (en)
JP (1) JP6157591B2 (en)
CA (1) CA2870770C (en)
ES (1) ES2683070T3 (en)
FR (1) FR2989876B1 (en)
SG (1) SG11201406848TA (en)
WO (1) WO2013160279A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8498695B2 (en) 2006-12-22 2013-07-30 Novadaq Technologies Inc. Imaging system with a single color image sensor for simultaneous fluorescence and color video endoscopy
MX2010010292A (en) 2008-03-18 2011-01-25 Novadaq Technologies Inc Imaging system for combined full-color reflectance and near-infrared imaging.
WO2014177607A1 (en) * 2013-05-03 2014-11-06 Koninklijke Philips N.V. Light source with adapted spectal output
AU2016351730B2 (en) 2015-11-13 2019-07-11 Novadaq Technologies Inc. Systems and methods for illumination and imaging of a target
CA3009419A1 (en) 2016-01-26 2017-08-03 Novadaq Technologies ULC Configurable platform
EP3205257B1 (en) * 2016-02-15 2022-11-16 Leica Instruments (Singapore) Pte Ltd Illumination filter for an illumination filter system of a surgical multispectral fluorescence microscope having a spatial filter pattern
USD916294S1 (en) 2016-04-28 2021-04-13 Stryker European Operations Limited Illumination and imaging device
CA3027592A1 (en) 2016-06-14 2017-12-21 John Josef Paul FENGLER Methods and systems for adaptive imaging for low light signal enhancement in medical visualization
FR3061849A1 (en) 2017-01-17 2018-07-20 Fluoptics METHOD AND DEVICE FOR MEASURING FLUORESCENCE EMITTED TO THE SURFACE OF A BIOLOGICAL TISSUE
US11140305B2 (en) 2017-02-10 2021-10-05 Stryker European Operations Limited Open-field handheld fluorescence imaging systems and methods
FR3073049B1 (en) 2017-10-26 2023-12-08 Fluoptics METHOD AND DEVICE FOR MONITORING FLUORESCENCE EMITTED ON THE SURFACE OF A BIOLOGICAL TISSUE
WO2019081833A1 (en) 2017-10-26 2019-05-02 Fluoptics Method and device for monitoring the fluorescence emitted at the surface of a biological tissue
CA3012946A1 (en) * 2018-07-31 2020-01-31 Oz Optics Ltd. Fiber-based broadband polarization-entangled photon source
CN109480776B (en) * 2018-10-30 2021-01-15 中国科学院自动化研究所 Intraoperative near-infrared first-region and second-region multi-spectral-segment fluorescent navigation system and use method thereof
FR3113515A1 (en) 2020-08-24 2022-02-25 Maquet Sas Surgical lighting device
FR3135610A1 (en) 2022-05-19 2023-11-24 Fluoptics Medical imaging device and method adapted to the observation of several spectral bands

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09540A (en) * 1995-06-19 1997-01-07 Fuji Photo Film Co Ltd Fluorescent image diagnostic device for operation
JP3962122B2 (en) * 1996-11-20 2007-08-22 オリンパス株式会社 Endoscope device
US8368034B2 (en) * 2006-06-29 2013-02-05 Cdex, Inc. Substance detection, inspection and classification system using enhanced photoemission spectroscopy
FR2924808B1 (en) * 2007-12-11 2010-09-03 Commissariat Energie Atomique SYSTEM FOR FLUORESCENCE ANALYSIS OF A FIELD IN A LIGHT AREA
DE102010044503B4 (en) * 2010-09-06 2017-11-02 Leica Microsystems (Schweiz) Ag Operations fluorescence stereomicroscope

Also Published As

Publication number Publication date
FR2989876A1 (en) 2013-11-01
JP6157591B2 (en) 2017-07-05
US20150083932A1 (en) 2015-03-26
CA2870770A1 (en) 2013-10-31
US11002680B2 (en) 2021-05-11
ES2683070T3 (en) 2018-09-24
JP2015520624A (en) 2015-07-23
WO2013160279A1 (en) 2013-10-31
FR2989876B1 (en) 2014-04-18
US20210055225A1 (en) 2021-02-25
EP2840953B1 (en) 2018-05-30
EP2840953A1 (en) 2015-03-04
CA2870770C (en) 2020-05-05

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