SG11201401656PA - N-methyl-2-[3-((e)-2-pyridin-2-yl-vinyl)-1h-indazol-6-ylsulfanyl]-benzamide for the treatment of chronic myelogenous leukemia - Google Patents
N-methyl-2-[3-((e)-2-pyridin-2-yl-vinyl)-1h-indazol-6-ylsulfanyl]-benzamide for the treatment of chronic myelogenous leukemiaInfo
- Publication number
- SG11201401656PA SG11201401656PA SG11201401656PA SG11201401656PA SG11201401656PA SG 11201401656P A SG11201401656P A SG 11201401656PA SG 11201401656P A SG11201401656P A SG 11201401656PA SG 11201401656P A SG11201401656P A SG 11201401656PA SG 11201401656P A SG11201401656P A SG 11201401656PA
- Authority
- SG
- Singapore
- Prior art keywords
- ylsulfanyl
- indazol
- benzamide
- pyridin
- vinyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161558915P | 2011-11-11 | 2011-11-11 | |
| PCT/IB2012/056168 WO2013068909A1 (en) | 2011-11-11 | 2012-11-05 | N-methyl-2-[3-((e)-2-pyridin-2-yl-vinyl)-1h-indazol-6-ylsulfanyl]-benzamide for the treatment of chronic myelogenous leukemia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201401656PA true SG11201401656PA (en) | 2014-10-30 |
Family
ID=47178246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201401656PA SG11201401656PA (en) | 2011-11-11 | 2012-11-05 | N-methyl-2-[3-((e)-2-pyridin-2-yl-vinyl)-1h-indazol-6-ylsulfanyl]-benzamide for the treatment of chronic myelogenous leukemia |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9205078B2 (ru) |
| EP (1) | EP2776031A1 (ru) |
| JP (1) | JP2014533262A (ru) |
| KR (1) | KR20140088556A (ru) |
| CN (1) | CN103917234A (ru) |
| AU (1) | AU2012335254A1 (ru) |
| BR (1) | BR112014011453A2 (ru) |
| CA (1) | CA2855211A1 (ru) |
| IL (1) | IL232427A0 (ru) |
| MX (1) | MX2014005715A (ru) |
| RU (1) | RU2014116407A (ru) |
| SG (1) | SG11201401656PA (ru) |
| TW (1) | TW201332548A (ru) |
| WO (1) | WO2013068909A1 (ru) |
| ZA (1) | ZA201403306B (ru) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2792360A1 (en) | 2013-04-18 | 2014-10-22 | IP Gesellschaft für Management mbH | (1aR,12bS)-8-cyclohexyl-11-fluoro-N-((1-methylcyclopropyl)sulfonyl)-1a-((3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl)-1,1a,2,2b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide for use in treating HCV |
| ES2899457T3 (es) | 2014-02-04 | 2022-03-11 | Pfizer | Combinación de un antagonista de PD-1 y un inhibidor de VEGFR para tratar el cáncer |
| WO2016032927A1 (en) | 2014-08-25 | 2016-03-03 | Pfizer Inc. | Combination of a pd-1 antagonist and an alk inhibitor for treating cancer |
| US10800846B2 (en) | 2015-02-26 | 2020-10-13 | Merck Patent Gmbh | PD-1/PD-L1 inhibitors for the treatment of cancer |
| WO2016205277A1 (en) | 2015-06-16 | 2016-12-22 | Merck Patent Gmbh | Pd-l1 antagonist combination treatments |
| IL265762B2 (en) | 2016-10-06 | 2024-04-01 | Merck Patent Gmbh | Dosing regimen of avolumab for cancer treatment |
| GB201820450D0 (en) * | 2018-12-14 | 2019-01-30 | Z Factor Ltd | Compound and its use for the treatment of alpha1-antitryspin deficiency |
| KR102205619B1 (ko) | 2019-06-12 | 2021-01-21 | 한국과학기술연구원 | 신규한 인다졸 유도체 화합물 및 이를 포함하는 암의 예방, 개선 또는 치료용 약학 조성물 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6177401B1 (en) | 1992-11-13 | 2001-01-23 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften | Use of organic compounds for the inhibition of Flk-1 mediated vasculogenesis and angiogenesis |
| US7141581B2 (en) | 1999-07-02 | 2006-11-28 | Agouron Pharmaceuticals, Inc. | Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use |
| TWI262914B (en) | 1999-07-02 | 2006-10-01 | Agouron Pharma | Compounds and pharmaceutical compositions for inhibiting protein kinases |
| CA2520932A1 (en) | 2003-04-03 | 2004-10-14 | Pfizer Inc. | Dosage forms comprising ag013736 |
| JP2008518904A (ja) | 2004-11-02 | 2008-06-05 | ファイザー・インク | ６−［２−（メチルカルバモイル）フェニルスルファニル］−３−ｅ−［２−（ピリジン−２−イル）エテニル］インダゾールの多形体形態 |
| KR20070058690A (ko) | 2004-11-02 | 2007-06-08 | 화이자 인코포레이티드 | 인다졸 화합물의 제조방법 |
| WO2006048746A2 (en) | 2004-11-02 | 2006-05-11 | Pfizer Inc. | Methods for the removal of heavy metals |
| CA2586176A1 (en) | 2004-11-02 | 2006-05-11 | Srinivasan Babu | Methods for preparing indazole compounds |
| CN101052633A (zh) | 2004-11-02 | 2007-10-10 | 辉瑞大药厂 | 制备吲唑化合物的方法 |
| EP1885338A1 (en) | 2005-05-19 | 2008-02-13 | Pfizer, Inc. | Pharmaceutical compostions comprising an amorphous form of a vegf-r inhibitor |
| NZ580126A (en) | 2007-04-05 | 2012-03-30 | Pfizer Prod Inc | Crystalline forms of 6- [2- (methylcarbamoyl) phenylsulfanyl] -3-e- [2- (pyridin-2-yl) ethenyl] indazole suitable for the treatment of abnormal cell growth in mammals |
| CN101204367A (zh) * | 2007-11-29 | 2008-06-25 | 济南帅华医药科技有限公司 | 一种治疗实体肿瘤的阿西替尼缓释植入剂 |
| CA2775155A1 (en) | 2009-10-01 | 2011-04-07 | Csl Limited | Method of treatment of philadelphia chromosome positive leukemia |
| MX2014003886A (es) | 2011-09-30 | 2014-05-13 | Pfizer | Composiciones farmaceuticas de n-metil-2-[3-((e) 2-piridin-2-il-vinil)-1h-indazol-6-ilsulfanil]benzamida. |
-
2012
- 2012-11-05 CA CA2855211A patent/CA2855211A1/en not_active Abandoned
- 2012-11-05 EP EP12784734.1A patent/EP2776031A1/en not_active Withdrawn
- 2012-11-05 SG SG11201401656PA patent/SG11201401656PA/en unknown
- 2012-11-05 JP JP2014540598A patent/JP2014533262A/ja not_active Withdrawn
- 2012-11-05 KR KR1020147012362A patent/KR20140088556A/ko not_active Application Discontinuation
- 2012-11-05 CN CN201280055067.4A patent/CN103917234A/zh active Pending
- 2012-11-05 AU AU2012335254A patent/AU2012335254A1/en not_active Abandoned
- 2012-11-05 US US14/356,847 patent/US9205078B2/en not_active Expired - Fee Related
- 2012-11-05 WO PCT/IB2012/056168 patent/WO2013068909A1/en active Application Filing
- 2012-11-05 MX MX2014005715A patent/MX2014005715A/es not_active Application Discontinuation
- 2012-11-05 RU RU2014116407/15A patent/RU2014116407A/ru not_active Application Discontinuation
- 2012-11-05 BR BR112014011453A patent/BR112014011453A2/pt not_active IP Right Cessation
- 2012-11-08 TW TW101141597A patent/TW201332548A/zh unknown
-
2014
- 2014-05-01 IL IL232427A patent/IL232427A0/en unknown
- 2014-05-08 ZA ZA2014/03306A patent/ZA201403306B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2776031A1 (en) | 2014-09-17 |
| CA2855211A1 (en) | 2013-05-16 |
| KR20140088556A (ko) | 2014-07-10 |
| JP2014533262A (ja) | 2014-12-11 |
| MX2014005715A (es) | 2014-05-28 |
| RU2014116407A (ru) | 2015-12-20 |
| IL232427A0 (en) | 2014-06-30 |
| TW201332548A (zh) | 2013-08-16 |
| AU2012335254A1 (en) | 2014-05-08 |
| BR112014011453A2 (pt) | 2017-05-02 |
| WO2013068909A1 (en) | 2013-05-16 |
| ZA201403306B (en) | 2015-05-27 |
| US9205078B2 (en) | 2015-12-08 |
| CN103917234A (zh) | 2014-07-09 |
| US20140288125A1 (en) | 2014-09-25 |
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