SG10202106462TA - Combination therapy for cancer treatment - Google Patents

Combination therapy for cancer treatment

Info

Publication number
SG10202106462TA
SG10202106462TA SG10202106462TA SG10202106462TA SG10202106462TA SG 10202106462T A SG10202106462T A SG 10202106462TA SG 10202106462T A SG10202106462T A SG 10202106462TA SG 10202106462T A SG10202106462T A SG 10202106462TA SG 10202106462T A SG10202106462T A SG 10202106462TA
Authority
SG
Singapore
Prior art keywords
combination therapy
cancer treatment
cancer
treatment
therapy
Prior art date
Application number
SG10202106462TA
Other languages
English (en)
Inventor
Robert A Beardsley
Dennis P Riley
Jeffery L Keene
Spitz, Jr
Melissa A Fath
Original Assignee
Galera Labs Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galera Labs Llc filed Critical Galera Labs Llc
Publication of SG10202106462TA publication Critical patent/SG10202106462TA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/655Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135Compounds containing heavy metals
    • A61K31/714Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/242Gold; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
SG10202106462TA 2016-05-03 2017-05-03 Combination therapy for cancer treatment SG10202106462TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662331253P 2016-05-03 2016-05-03

Publications (1)

Publication Number Publication Date
SG10202106462TA true SG10202106462TA (en) 2021-07-29

Family

ID=60203338

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10202106462TA SG10202106462TA (en) 2016-05-03 2017-05-03 Combination therapy for cancer treatment
SG11201809606YA SG11201809606YA (en) 2016-05-03 2017-05-03 Combination therapy for cancer treatment

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201809606YA SG11201809606YA (en) 2016-05-03 2017-05-03 Combination therapy for cancer treatment

Country Status (14)

Country Link
US (1) US20190151331A1 (ru)
EP (1) EP3452060A4 (ru)
JP (2) JP2019514962A (ru)
KR (2) KR20230075528A (ru)
CN (1) CN109414454A (ru)
AU (2) AU2017260425B2 (ru)
BR (1) BR112018072560A2 (ru)
CA (1) CA3022699A1 (ru)
CL (1) CL2018003123A1 (ru)
EA (1) EA201892510A3 (ru)
IL (3) IL300085A (ru)
MX (1) MX2018013354A (ru)
SG (2) SG10202106462TA (ru)
WO (1) WO2017192740A2 (ru)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2725023T3 (es) 2006-10-12 2019-09-18 Galera Labs Llc Métodos para el tratamiento de la mucositis oral
WO2013048965A1 (en) 2011-09-26 2013-04-04 Galera Therapeutics, Llc Methods for treatment of diseases
RS60558B1 (sr) 2015-08-11 2020-08-31 Galera Labs Llc Pentaaza makrociklični prstenasti kompleksi koji poseduju oralnu bioraspoloživost
SG11201809126RA (en) 2016-05-03 2018-11-29 Bayer Pharma AG Aromatic sulfonamide derivatives
US11219614B2 (en) 2016-09-01 2022-01-11 Galera Labs, Llc Combination cancer therapy with pentaaza macrocyclic ring complex and ascorbate compound
IL269915B (en) 2017-04-13 2022-09-01 Galera Labs Llc Cancer immunotherapy combined with a macrocyclic ring pentase complex
WO2019098288A1 (ja) * 2017-11-15 2019-05-23 学校法人 慶應義塾 抗腫瘍剤及び配合剤
US20200397817A1 (en) * 2017-11-30 2020-12-24 SHIEH, Darbin Method for predicting and modulating susceptibility of cancer cell to programmed cell death
GB201800733D0 (en) * 2018-01-17 2018-02-28 Cambridge Entpr Ltd Cancer
JP2019131508A (ja) * 2018-01-31 2019-08-08 ガレラ・ラブス・リミテッド・ライアビリティ・カンパニーGalera Labs, Llc ペンタアザ大環状環複合体および白金を基にした抗癌剤による組み合わせ癌療法
WO2019152661A1 (en) * 2018-01-31 2019-08-08 Galera Labs, Llc Combination cancer therapy with pentaaza macrocyclic ring complex and platinum-based anticancer agent
WO2019232648A1 (en) * 2018-06-08 2019-12-12 Atomic Energy Of Canada Limited / Énergie Atomique Du Canada Limitée Use of a checkpoint inhibitor in combination with ultralow dose whole body irradiation
CN109620836B (zh) * 2018-12-24 2021-05-18 陕西科技大学 一种具有抗乳腺癌作用的复方药物组合物及其用途和基于此组合物的药物
WO2021050490A1 (en) * 2019-09-13 2021-03-18 The Trustees Of Columbia University In The City Of New York Methods of enhancing radiotherapy using ferroptosis inducers as radiosensitizers
CN114502179A (zh) * 2019-10-10 2022-05-13 加莱拉实验室有限责任公司 含锰配合物的水性制剂的制备方法、制剂和治疗方法
EP4157242A1 (en) * 2020-06-02 2023-04-05 Galera Labs, LLC Combination cancer therapy with pentaaza macrocyclic ring complex and hormone therapy agent
WO2022026753A1 (en) * 2020-07-29 2022-02-03 University Of Kentucky Research Foundation Gold(iii) compounds and cancer cell-selective modulation of mitochondrial respiration and metabolism
WO2024026273A1 (en) * 2022-07-25 2024-02-01 Galera Labs, Llc Therapy for reduced ototoxicity from chemotherapeutic agent with pentaaza macrocyclic ring complex

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2859916B1 (en) * 2008-05-22 2017-11-29 Galera Labs, LLC Combination of an antimitotic agent and a selective superoxide dismutase mimetic in antitumor therapy
WO2010049182A2 (en) * 2008-10-29 2010-05-06 Istituto Superiore Di Sanitá Treatment of retroviral reservoirs exploiting oxidative stress
WO2013048965A1 (en) * 2011-09-26 2013-04-04 Galera Therapeutics, Llc Methods for treatment of diseases

Also Published As

Publication number Publication date
KR20180132939A (ko) 2018-12-12
SG11201809606YA (en) 2018-11-29
IL290149A (en) 2022-03-01
JP2023036950A (ja) 2023-03-14
AU2017260425B2 (en) 2023-04-06
IL262661B (en) 2022-03-01
CA3022699A1 (en) 2017-11-09
CN109414454A (zh) 2019-03-01
IL300085A (en) 2023-03-01
MX2018013354A (es) 2019-02-20
JP2019514962A (ja) 2019-06-06
EA201892510A3 (ru) 2019-09-30
CL2018003123A1 (es) 2019-05-03
EA201892510A2 (ru) 2019-06-28
AU2023204318A1 (en) 2023-07-27
KR20230075528A (ko) 2023-05-31
BR112018072560A2 (pt) 2019-02-19
US20190151331A1 (en) 2019-05-23
AU2017260425A1 (en) 2018-11-22
WO2017192740A2 (en) 2017-11-09
IL262661A (en) 2018-12-31
EP3452060A2 (en) 2019-03-13
EP3452060A4 (en) 2020-01-01

Similar Documents

Publication Publication Date Title
IL290149A (en) Combined treatment for cancer
HK1247129A1 (zh) 治療癌症的聯合療法
IL254705B (en) Combined treatment for cancer
IL255060A0 (en) Combined treatment for cancer
HK1251475A1 (zh) 用於癌症治療的聯合療法
EP3180010A4 (en) Combination therapy for treating cancer
PT3423087T (pt) Terapia de cpombinação contra o cancro
EP3407978A4 (en) COMBINATION THERAPY FOR TREATING CANCER
IL267795A (en) Combined treatment for cancer
EP3258965A4 (en) Combination therapy for cancer treatment
HK1258319A1 (zh) 癌症療法
IL263802A (en) Combinations of cancer treatments
EP3193884A4 (en) Combination therapy for treating cancer
IL274837B1 (en) Combined treatment for cancer
IL266993A (en) Combined therapy for cancer treatment
HK1251794A1 (zh) 癌症治療
IL258494A (en) Rational combined therapy for cancer treatment
HK1254687A1 (zh) 用於癌症的聯合療法
IL253642A0 (en) Combined treatment for cancer
HRP20210383T8 (hr) Kombinirana terapija za rak
GB201601248D0 (en) Cancer therapy