SG10201811177SA - Cell culture methods and media comprising n-acetylcysteine - Google Patents

Cell culture methods and media comprising n-acetylcysteine

Info

Publication number
SG10201811177SA
SG10201811177SA SG10201811177SA SG10201811177SA SG10201811177SA SG 10201811177S A SG10201811177S A SG 10201811177SA SG 10201811177S A SG10201811177S A SG 10201811177SA SG 10201811177S A SG10201811177S A SG 10201811177SA SG 10201811177S A SG10201811177S A SG 10201811177SA
Authority
SG
Singapore
Prior art keywords
cell culture
acetylcysteine
culture methods
media
cells
Prior art date
Application number
SG10201811177SA
Other languages
English (en)
Inventor
Brena Holman
Jeong Lee
Original Assignee
Medimmune Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimmune Llc filed Critical Medimmune Llc
Publication of SG10201811177SA publication Critical patent/SG10201811177SA/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/32Amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/34Sugars
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/36Lipids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/44Thiols, e.g. mercaptoethanol
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999Small molecules not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2511/00Cells for large scale production

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
SG10201811177SA 2014-06-18 2015-06-17 Cell culture methods and media comprising n-acetylcysteine SG10201811177SA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462013699P 2014-06-18 2014-06-18

Publications (1)

Publication Number Publication Date
SG10201811177SA true SG10201811177SA (en) 2019-01-30

Family

ID=54936063

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201609980TA SG11201609980TA (en) 2014-06-18 2015-06-17 Cell culture methods and media comprising n-acetylcysteine
SG10201811177SA SG10201811177SA (en) 2014-06-18 2015-06-17 Cell culture methods and media comprising n-acetylcysteine

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201609980TA SG11201609980TA (en) 2014-06-18 2015-06-17 Cell culture methods and media comprising n-acetylcysteine

Country Status (14)

Country Link
US (3) US20170204362A1 (zh)
EP (1) EP3158077B1 (zh)
JP (4) JP2017518064A (zh)
KR (2) KR20220119179A (zh)
CN (1) CN106715707A (zh)
AU (3) AU2015277230A1 (zh)
BR (1) BR112016027797A2 (zh)
CA (1) CA2952241A1 (zh)
ES (1) ES2947286T3 (zh)
IL (1) IL249202A0 (zh)
MX (1) MX2016015785A (zh)
RU (1) RU2017101195A (zh)
SG (2) SG11201609980TA (zh)
WO (1) WO2015195758A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108697730A (zh) 2015-12-18 2018-10-23 泰佳医疗公司 细胞糖胺聚糖组合物及其制备和使用方法
EP3492582A1 (en) 2017-12-01 2019-06-05 UCB Biopharma SPRL Cell culture methods
US20220305049A1 (en) * 2019-08-27 2022-09-29 Tega Therapeutics, Inc. Heparin and heparan sulfate from modified mst cells and methods of making and using

Family Cites Families (18)

* Cited by examiner, † Cited by third party
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US4927762A (en) * 1986-04-01 1990-05-22 Cell Enterprises, Inc. Cell culture medium with antioxidant
US5892019A (en) 1987-07-15 1999-04-06 The United States Of America, As Represented By The Department Of Health And Human Services Production of a single-gene-encoded immunoglobulin
US5859205A (en) * 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
CN1096540A (zh) * 1993-06-15 1994-12-21 中国科学院化工冶金研究所 气升式悬浮微载体培养贴壁依赖细胞
US20030119185A1 (en) 2000-02-24 2003-06-26 Xcyte Therapies, Inc. Activation and expansion of cells
US7501231B2 (en) * 2001-03-23 2009-03-10 University Of Ottawa Methods and compositions for cryopreservation of dissociated primary animal cells
US20030096414A1 (en) 2001-03-27 2003-05-22 Invitrogen Corporation Culture medium for cell growth and transfection
AU2003226065B2 (en) 2002-04-12 2009-02-26 Ludwig Institute For Cancer Research, Ltd Recombinant anti-interleukin-9 antibodies
KR101044538B1 (ko) * 2002-09-05 2011-06-27 버베리안 노딕 에이/에스 무혈청 조건하에서 일차세포의 배양 및 바이러스의 증식방법
KR20050088118A (ko) 2002-12-13 2005-09-01 세로고스 배양 배지 조성물, 배양 방법, 및 얻어진 근원세포, 및그들의 용도
CN100402660C (zh) * 2002-12-23 2008-07-16 布里斯托尔-迈尔斯斯奎布公司 用于蛋白质生产的哺乳动物细胞培养方法中产物质量提高
CA2521826C (en) 2003-04-11 2013-08-06 Jennifer L. Reed Recombinant il-9 antibodies and uses thereof
GB0407315D0 (en) * 2003-07-15 2004-05-05 Cambridge Antibody Tech Human antibody molecules
MXPA06000258A (es) * 2003-07-15 2006-07-03 Cambridge Antibody Tech Moleculas de anticuerpo humano para interleucina-13.
DK1711528T3 (da) * 2003-12-23 2012-08-20 Genentech Inc Behandling af cancer med hidtil ukendte anti-il 13 monoklonale antistoffer
NZ575328A (en) * 2006-09-13 2012-06-29 Abbott Lab Cell culture improvements
US20110262965A1 (en) * 2010-04-23 2011-10-27 Life Technologies Corporation Cell culture medium comprising small peptides
IE20110008A1 (en) 2011-01-12 2012-08-01 Patrick Thomas Prendergast Compositions for alleviating:- stress, anxiety, depression and aiding with weight loss

Also Published As

Publication number Publication date
EP3158077A4 (en) 2018-01-17
US20170204362A1 (en) 2017-07-20
IL249202A0 (en) 2017-01-31
BR112016027797A2 (pt) 2017-10-31
KR20170020482A (ko) 2017-02-22
RU2017101195A (ru) 2018-07-20
MX2016015785A (es) 2017-04-25
AU2019204934B2 (en) 2020-11-12
WO2015195758A1 (en) 2015-12-23
JP2017518064A (ja) 2017-07-06
KR20220119179A (ko) 2022-08-26
CN106715707A (zh) 2017-05-24
JP2022046609A (ja) 2022-03-23
SG11201609980TA (en) 2016-12-29
JP2020146051A (ja) 2020-09-17
EP3158077A1 (en) 2017-04-26
AU2019204934A1 (en) 2019-07-25
JP2024035242A (ja) 2024-03-13
RU2017101195A3 (zh) 2019-02-19
US11555175B2 (en) 2023-01-17
CA2952241A1 (en) 2015-12-23
ES2947286T3 (es) 2023-08-04
EP3158077B1 (en) 2023-04-05
US20230057856A1 (en) 2023-02-23
US20200208100A1 (en) 2020-07-02
KR102434588B1 (ko) 2022-08-22
AU2015277230A1 (en) 2017-01-05
AU2020260408A1 (en) 2020-11-26

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