SG10201804313SA - Apparatus and methods of use - Google Patents

Apparatus and methods of use

Info

Publication number
SG10201804313SA
SG10201804313SA SG10201804313SA SG10201804313SA SG10201804313SA SG 10201804313S A SG10201804313S A SG 10201804313SA SG 10201804313S A SG10201804313S A SG 10201804313SA SG 10201804313S A SG10201804313S A SG 10201804313SA SG 10201804313S A SG10201804313S A SG 10201804313SA
Authority
SG
Singapore
Prior art keywords
methods
dcs
disclosure relates
chemical agents
disposable containers
Prior art date
Application number
SG10201804313SA
Inventor
Eric Rudolph
Pete Silverberg
Candice Kofsky
Paul Kubera
Barry Reiss
Original Assignee
Abec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abec Inc filed Critical Abec Inc
Publication of SG10201804313SA publication Critical patent/SG10201804313SA/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01M—TESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
    • G01M3/00—Investigating fluid-tightness of structures
    • G01M3/02—Investigating fluid-tightness of structures by using fluid or vacuum
    • G01M3/26—Investigating fluid-tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors
    • G01M3/32—Investigating fluid-tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors for containers, e.g. radiators
    • G01M3/3281—Investigating fluid-tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors for containers, e.g. radiators removably mounted in a test cell
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/02—Filters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05—Stirrers
    • B01F27/07—Stirrers characterised by their mounting on the shaft
    • B01F27/071—Fixing of the stirrer to the shaft
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/80—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
    • B01F27/91—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with propellers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/31—Couplings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/50—Mixing receptacles
    • B01F35/513—Flexible receptacles, e.g. bags supported by rigid containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/04—Methods of, or means for, filling the material into the containers or receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D21/00—Nestable, stackable or joinable containers; Containers of variable capacity
    • B65D21/02—Containers specially shaped, or provided with fittings or attachments, to facilitate nesting, stacking, or joining together
    • B65D21/0233—Nestable containers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/28—Constructional details, e.g. recesses, hinges disposable or single use
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/04—Seals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01M—TESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
    • G01M3/00—Investigating fluid-tightness of structures
    • G01M3/02—Investigating fluid-tightness of structures by using fluid or vacuum
    • G01M3/26—Investigating fluid-tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors
    • G01M3/32—Investigating fluid-tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors for containers, e.g. radiators
    • G01M3/3209—Details, e.g. container closure devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01M—TESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
    • G01M3/00—Investigating fluid-tightness of structures
    • G01M3/02—Investigating fluid-tightness of structures by using fluid or vacuum
    • G01M3/26—Investigating fluid-tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors
    • G01M3/32—Investigating fluid-tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors for containers, e.g. radiators
    • G01M3/3236—Investigating fluid-tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors for containers, e.g. radiators by monitoring the interior space of the containers
    • G01M3/3272—Investigating fluid-tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors for containers, e.g. radiators by monitoring the interior space of the containers for verifying the internal pressure of closed containers

Abstract

APPARATUS AND METHODS OF USE This disclosure relates to equipment utilized to manufacture chemical agents, particularly biopharmaceuticals, using Disposable Containers (DCs). FIGURE 1 5
SG10201804313SA 2013-12-10 2014-12-09 Apparatus and methods of use SG10201804313SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361913960P 2013-12-10 2013-12-10
US201462054557P 2014-09-24 2014-09-24

Publications (1)

Publication Number Publication Date
SG10201804313SA true SG10201804313SA (en) 2018-07-30

Family

ID=53371757

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10201804313SA SG10201804313SA (en) 2013-12-10 2014-12-09 Apparatus and methods of use

Country Status (7)

Country Link
US (4) US10519415B2 (en)
EP (2) EP3825394B1 (en)
KR (1) KR102377615B1 (en)
CN (2) CN106102687B (en)
DK (2) DK3065691T3 (en)
SG (1) SG10201804313SA (en)
WO (1) WO2015089056A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10372100B2 (en) * 2016-08-29 2019-08-06 Ge Healthcare Bio-Sciences Corp. Manufacturing system for biopharmaceutical products
JP7372912B2 (en) 2017-10-03 2023-11-01 エイベック，インコーポレイテッド Reactor system
CA3106987A1 (en) * 2018-07-27 2020-01-30 Abec, Inc. Disposable containers and reaction systems
BR112021015000A2 (en) * 2019-02-01 2021-10-05 Abec, Inc. REACTION SYSTEMS
WO2023215564A2 (en) 2022-05-06 2023-11-09 Abec, Inc. Bioreactor systems

Family Cites Families (106)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US609595A (en) 1898-08-23 Air-heating radiator
US131875A (en) 1872-10-01 Improvement in heating-drums
US2162400A (en) 1936-08-26 1939-06-13 Emery A Heath Removable motor mount and adapter for mixers, churns, and the like
US2973944A (en) 1955-02-10 1961-03-07 Frick Co Heat transfer apparatus
US3056664A (en) 1959-03-12 1962-10-02 Standard Oil Co Apparatus for handling corrosive materials at high pressures and temperatures
US3177932A (en) 1963-06-24 1965-04-13 Hupp Corp Drum type heat transfer apparatus
AT247823B (en) 1964-05-08 1966-06-27 Vogelbusch Gmbh Device for gassing liquids in a container
NO117924B (en) 1964-12-07 1969-10-13 Boliden Ab
US3380513A (en) 1966-09-26 1968-04-30 Du Pont Heat exchange arrangement
GB1211270A (en) 1968-12-24 1970-11-04 Nestle Sa Agitation device
US3662817A (en) 1970-05-26 1972-05-16 Du Pont A process for accomplishing heat exchange between a corrosive liquid process stream and a second liquid
US3762212A (en) 1971-07-15 1973-10-02 Advanced Technologies Inc Leak testing apparatus and methods
US3776042A (en) 1972-03-22 1973-12-04 Ladish Co Aseptic sampler fitting
US3779082A (en) 1972-10-04 1973-12-18 Galloway Co Aseptic sample fitting
JPS5023773U (en) 1973-03-28 1975-03-17
CH578618A5 (en) 1973-08-30 1976-08-13 Mueller Hans Maennedorf
ES440412A1 (en) 1974-08-29 1977-07-01 Hoechst Ag Polymerization reactor with gilled-tube radiator and axial agitator
US4212950A (en) 1978-05-08 1980-07-15 The Virtis Company, Inc. Fermenting apparatus
JPS6011408B2 (en) 1978-05-24 1985-03-26 古河電気工業株式会社 Extruded insulated cable continuous cooling device
US4207180A (en) 1979-01-11 1980-06-10 Chang Shih Chih Gas-liquid reaction method and apparatus
US4426959A (en) 1980-07-01 1984-01-24 Q-Dot Corporation Waste heat recovery system having thermal sleeve support for heat pipe
JPS57125202A (en) 1981-01-28 1982-08-04 Mitsui Toatsu Chem Inc Device for continuous bulk polymerization
US4588024A (en) 1982-03-09 1986-05-13 Phillips Petroleum Company Indirect heat exchanger with baffles
JPS6011408A (en) 1983-06-30 1985-01-21 Tokuyama Soda Co Ltd Composite filler
DE3340353A1 (en) 1983-11-08 1985-05-15 Pfanni-Werke Otto Eckart KG, 8000 München Method and device for detecting leaks in sealed containers
US4534208A (en) * 1983-11-09 1985-08-13 Motorola, Inc. Method and apparatus for testing a sealed container
BR8600564A (en) 1985-02-11 1986-10-21 Falvourtech Pty Ltd CONTRA-CURRENT CONTACT DEVICE OR DISTILLATION COLUMN, SYSTEM TO REDUCE THE ALCOHOLIC CONTENT OF A DRINK CONTAINING ALCOHOL, SYSTEM TO REDUCE THE ALCOHOLIC CONTENT OF WINE, SYSTEM FOR REMOVING AROMA AND / OR TASTE OF FRUIT JUICE, DE-DESULFURIZING A LIQUID AND PROCESS TO DISTILL, DISTILL BY FRACTIONATION OR REMOVE A SELECTED VOLATILE COMPONENT, OR COMPONENTS OF A LIQUID
US4588085A (en) 1985-03-11 1986-05-13 Cordis Corporation Sterile air feedthrough packaging system for testing hydrocephalus shunt valves
US4670397A (en) 1986-02-05 1987-06-02 Phillips Petroleum Company Fermentation apparatus
EP0293450A4 (en) 1986-12-12 1989-10-27 Moisseeff Advanced Technology Internal combustion engine radiator.
JPH0689047B2 (en) 1987-03-27 1994-11-09 新日鐵化学株式会社 Polymerization reactor
US4847203A (en) 1987-08-31 1989-07-11 Allelix, Inc. Fermentation vessels
US4919906A (en) 1988-06-03 1990-04-24 James C. Barber And Associates, Inc. Processes and equipment for production of elemental phosphorus and thermal phosphoric acid
US4932533A (en) 1989-02-10 1990-06-12 Allpak Container, Inc. Thermal-stabilized container
US5174928A (en) 1990-01-31 1992-12-29 Silk Partnership Gas and liquid contacting process
CA2014813C (en) 1990-04-18 1999-07-27 David Clifford Riley Pouch tester
US5220535A (en) 1991-06-18 1993-06-15 Raytheon Company Sonar baffles
JPH07104224B2 (en) 1991-12-11 1995-11-13 株式会社コスモ計器 Leak inspection device
US5203458A (en) * 1992-03-02 1993-04-20 Quality Containers International, Inc. Cryptoplate disposable surgical garment container
US5513516A (en) 1992-05-01 1996-05-07 Visi-Pack, Inc. Method and apparatus for leak testing a container
CH685887A5 (en) 1992-08-12 1995-10-31 Martin Lehmann Container leakage testing device
AT403550B (en) 1992-08-18 1998-03-25 Robocon Lab Ind Roboter INCUBATOR
US5600052A (en) 1994-05-02 1997-02-04 Uop Process and apparatus for controlling reaction temperatures
JP3444970B2 (en) 1994-06-22 2003-09-08 麒麟麦酒株式会社 Roller bottle handling system
JPH0882568A (en) 1994-09-13 1996-03-26 Exedy Corp Device and method for leak detection
US5599507A (en) 1994-11-09 1997-02-04 Shaw; Gordon Reactor apparatus for preparing a polymeric material
US20030219453A1 (en) 1998-03-19 2003-11-27 Smithkline Beecham Biologicals, Sa Vaccines
FR2734633B1 (en) 1995-05-24 1997-06-20 Cit Alcatel INSTALLATION FOR DETECTING THE PRESENCE OF HELIUM IN A FLUID CIRCUIT
FI105906B (en) * 1997-03-12 2000-10-31 Mamec Oy A container mixer
EP0791814A3 (en) 1997-05-26 1997-11-26 Martin Lehmann Method for leak testing and leak testing apparatus
US6955793B1 (en) 1997-06-18 2005-10-18 Arencibia Jr Jose P Temperature controlled reaction vessel
US5989500A (en) 1997-07-02 1999-11-23 Phillips Petroleum Company Reactor heat exchange system
US5985347A (en) 1998-03-25 1999-11-16 Damrow Company, Inc. Cheese processing vat and method
US6197573B1 (en) 1998-11-17 2001-03-06 Biocon India Limited Solid state fermentation
US6254143B1 (en) 1999-04-21 2001-07-03 Central States Industrial Equipment And Service, Inc. Transfer panel assembly and method of construction
EP1172138B1 (en) 2000-07-14 2005-12-07 Biazzi Sa Apparatus and heat exchanger therefor
DK1320738T3 (en) * 2000-09-26 2009-06-15 Martin Lehmann Method and apparatus for leakage testing of closed containers
US6460405B1 (en) 2000-10-02 2002-10-08 Mocon, Inc. Method for measuring gas leakage from sealed packages
EP1360445B1 (en) 2001-02-05 2007-08-29 Showa Denko K.K. Duplex-type heat exchanger and refrigeration system equipped with said heat exchanger
CA2437391C (en) 2001-02-06 2010-04-20 Levtech, Inc. Apparatus and method for mixing materials sealed in a container under sterile conditions
EP1616938B1 (en) 2001-03-16 2007-12-12 Colder Products Company Sterilized assembly for bioprocessing and connecting method
US6923567B2 (en) 2002-04-12 2005-08-02 Hynetics Llc Mixing tank assembly
US6793012B2 (en) 2002-05-07 2004-09-21 Valeo, Inc Heat exchanger
JP4235429B2 (en) 2002-10-17 2009-03-11 キヤノン株式会社 Method for measuring gas in sealed container, and method for manufacturing sealed container and image display device
US8376029B2 (en) 2002-10-29 2013-02-19 Duramax Marine, Llc Keel cooler with fluid flow diverter
US7832923B2 (en) * 2002-12-09 2010-11-16 Dynamix Agitators Inc. Mounting assembly for plastic bulk container
US7153021B2 (en) * 2003-03-28 2006-12-26 Hyclone Laboratories, Inc. Container systems for mixing fluids with a magnetic stir bar
US20050087434A1 (en) * 2003-10-22 2005-04-28 Gregorio Tarancon Method and apparatus for transforming chemical fluids using halogen or oxygen in a photo-treatment process
WO2005108546A2 (en) 2004-04-27 2005-11-17 Baxter International Inc. Stirred-tank reactor system
US7231811B2 (en) 2004-05-07 2007-06-19 Nehemia Sagi Adaptive leak testing method
EP1773976B2 (en) 2004-06-04 2020-01-01 Global Life Sciences Solutions USA LLC Disposable bioreactor systems and methods
US7373944B2 (en) 2004-12-27 2008-05-20 Autoliv Asp, Inc. Pyrotechnic relief valve
US7682823B1 (en) 2005-01-04 2010-03-23 Larry Runyon Bioreactor systems
US7650933B2 (en) 2005-03-14 2010-01-26 Allied Engineering Company, Division Of E-Z-Rect Manufacturing Ltd. Baffle for sealed combustion chamber
US7682067B2 (en) * 2005-04-22 2010-03-23 Hyclone Laboratories, Inc. Mixing systems and related mixers
US7879599B2 (en) * 2005-04-22 2011-02-01 Hyclone Laboratories, Inc. Tube ports and related container systems
US7565828B2 (en) 2005-06-10 2009-07-28 Donbar Industries, Inc. Systems and methods for testing packaging
WO2008040567A1 (en) 2006-10-03 2008-04-10 Artelis Flexible mixing bag, mixing device and mixing system
WO2008040568A1 (en) 2006-10-03 2008-04-10 Artelis Mixing system including a flexible bag, specific flexible bag and locating system for the mixing system
DE102005052683B4 (en) 2005-10-27 2012-05-31 Visteon Global Technologies Inc. Multi-channel flat tube for heat exchangers
JP5197013B2 (en) 2005-11-01 2013-05-15 株式会社メディネット Shaking apparatus for cell culture and shaking culture method of cell culture method
US20070169916A1 (en) 2006-01-20 2007-07-26 Wand Steven M Double-wall, vented heat exchanger
US7815851B1 (en) 2006-04-13 2010-10-19 Lewis Robert W Steam sterilization system for sterilizing medical waste
DE102006018824A1 (en) 2006-04-22 2007-10-25 Bayer Technology Services Gmbh Disposable bioreactor
DE102006021852A1 (en) 2006-05-09 2007-11-15 Infors Ag Cabinet as well as processing method
JP5254226B2 (en) 2006-07-14 2013-08-07 エクセレレックス インク． Environmental protection containment system
JP4403169B2 (en) 2006-12-15 2010-01-20 株式会社日立製作所 Cell culture apparatus and control method thereof
WO2008151105A1 (en) 2007-06-04 2008-12-11 Ge Healthcare Bioscience Bioprocess Corp. An apparatus for mixing the contents of a container
EP2062640A1 (en) 2007-11-26 2009-05-27 Methanol Casale S.A. Chemical reactor with plate heat exchange unit
DE102007060291B4 (en) 2007-12-12 2011-04-28 Sartorius Stedim Biotech Gmbh Container arrangement with a container with flexible wall
FR2926885B1 (en) 2008-01-28 2010-03-12 Sartorius Stedim Biotech Sa METHOD AND APPARATUS FOR INTEGRITY CONTROL OF A NON-POROUS BELLOWSET FLEXIBLE POUCH (S)
CN101977674B (en) * 2008-03-19 2013-06-19 赛多利斯司特蒂姆生物工艺公司 Disposable mixing vessel
CN103542987B (en) * 2008-03-31 2017-05-10 Atmi包装公司 Apparatus and method for the integrity testing of flexible containers
US8381780B2 (en) 2008-05-22 2013-02-26 Xcellerex, Inc. Lift and support assemblies and methods for collapsible bag containers of vessels and bioreactors
US8420383B2 (en) 2008-09-09 2013-04-16 Biomerieux, Inc. Incubation system with low temperature enclosure
CN102378892A (en) 2009-04-03 2012-03-14 开利公司 Multi-circuit heat exchanger
DE102009019697A1 (en) 2009-05-05 2010-11-18 Bayer Technology Services Gmbh Container
US8658419B2 (en) 2009-09-04 2014-02-25 Abec, Inc. Heat transfer baffle system and uses thereof
US8506198B2 (en) * 2010-02-01 2013-08-13 Hyclone Laboratories, Inc. Self aligning coupling for mixing system
DE102010009345B4 (en) * 2010-02-25 2011-09-22 Schuler Cartec Gmbh & Co. Kg Method and tool for producing a component and a component produced by deformation
CN103930196B (en) 2011-03-15 2016-10-12 Abec公司 Reactor assembly
AU2012308611B2 (en) * 2011-09-16 2016-12-22 Global Life Sciences Solutions Usa Llc Single-use mixing and bioreactor systems
US9376655B2 (en) * 2011-09-29 2016-06-28 Life Technologies Corporation Filter systems for separating microcarriers from cell culture solutions
FR2985518B1 (en) * 2012-01-05 2014-02-07 Sartorius Stedim Biotech Sa CONTAINER FOR BIOPHARMACEUTICAL CONTENT.
US9284521B2 (en) 2012-03-24 2016-03-15 Therapeutic Proteins International, LLC Pivoting pressurized single-use bioreactor
US8534120B1 (en) * 2012-09-14 2013-09-17 Advanced Scientifics, Inc. Test system and method for flexible containers

Also Published As

Publication number Publication date
US20200308527A1 (en) 2020-10-01
US11168296B2 (en) 2021-11-09
EP3065691A4 (en) 2018-01-10
DK3065691T3 (en) 2021-02-01
EP3065691A1 (en) 2016-09-14
EP3825394A1 (en) 2021-05-26
WO2015089056A1 (en) 2015-06-18
US20230235265A1 (en) 2023-07-27
US20160272931A1 (en) 2016-09-22
EP3825394B1 (en) 2023-10-25
US20220135927A1 (en) 2022-05-05
CN106102687B (en) 2021-02-26
KR102377615B1 (en) 2022-03-22
US11649426B2 (en) 2023-05-16
DK3825394T3 (en) 2024-01-15
EP3065691B1 (en) 2020-10-28
US10519415B2 (en) 2019-12-31
CN106102687A (en) 2016-11-09
KR20160095016A (en) 2016-08-10
CN109679822A (en) 2019-04-26

Similar Documents

Publication Publication Date Title
PH12020550781A1 (en) Anti-jagged1 antibodies and methods of use
PH12018500711A1 (en) Anti-pd1 antibodies and methods of use
NZ731467A (en) Anti-tim3 antibodies and methods of use
PH12016501894B1 (en) Anti-ox40 antibodies and methods of use
MX2017007049A (en) ANTI-CD79b ANTIBODIES AND METHODS OF USE.
PH12014502601A1 (en) ANTI-Ly6E ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE
PH12015501954A1 (en) Anti-b7-h4 antibodies and immunoconjugates
MX2013008390A (en) Preparation of metal-triazolate frameworks.
IL240829A0 (en) Perfluorinated cyclopropyl fused 1, 3 - oxazin - 2 - amine compounds as beta - secretase inhibitors and methods of use
IN2015DN02875A (en)
NZ761537A (en) Anti-human ox40l antibodies, uses & methods
PH12014501605A1 (en) Anti-lrp5 antibodies and methods of use
MY192466A (en) Processes for the preparation of an apoptosis-inducing agent
MX2016009858A (en) Anti-pcsk9~glp-1 fusions and methods for use.
MX2017000142A (en) Mesenchymal stromal cells for treating sepsis.
SG10201804313SA (en) Apparatus and methods of use
MX357675B (en) Anti-jagged anitbodies and methods of use.
IN2013MU00848A (en)
GEP201706626B (en) Synthesis of (s)-nifuratel
AU352731S (en) Safety apparatus
MX2020011946A (en) Nmda antagonist prodrugs.
MX2017017119A (en) High concentration formulation.
IN2014MU03425A (en)
MX2016004573A (en) Nsp4 inhibitors and methods of use.
EP2843085A4 (en) Method for generating oxygen, device for electrolyzing water, and anode