SG10201403758SA - Methods and compositions for use in cellular therapies - Google Patents
Methods and compositions for use in cellular therapiesInfo
- Publication number
- SG10201403758SA SG10201403758SA SG10201403758SA SG10201403758SA SG10201403758SA SG 10201403758S A SG10201403758S A SG 10201403758SA SG 10201403758S A SG10201403758S A SG 10201403758SA SG 10201403758S A SG10201403758S A SG 10201403758SA SG 10201403758S A SG10201403758S A SG 10201403758SA
- Authority
- SG
- Singapore
- Prior art keywords
- compositions
- methods
- cellular therapies
- therapies
- cellular
- Prior art date
Links
- 238000002659 cell therapy Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Nutrition Science (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22427509P | 2009-07-09 | 2009-07-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201403758SA true SG10201403758SA (en) | 2014-10-30 |
Family
ID=42782196
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201403758SA SG10201403758SA (en) | 2009-07-09 | 2010-07-09 | Methods and compositions for use in cellular therapies |
| SG2012001574A SG177582A1 (en) | 2009-07-09 | 2010-07-09 | Methods and compositions for use in cellular therapies |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2012001574A SG177582A1 (en) | 2009-07-09 | 2010-07-09 | Methods and compositions for use in cellular therapies |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US8679834B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2451943B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5892931B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101788885B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN107007626A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2010269962B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112012000534A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2767300C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2451943T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2479542T3 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE031921T2 (cg-RX-API-DMAC7.html) |
| IL (1) | IL217377A (cg-RX-API-DMAC7.html) |
| MX (1) | MX359639B (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ597975A (cg-RX-API-DMAC7.html) |
| PL (1) | PL2451943T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2451943T (cg-RX-API-DMAC7.html) |
| RU (1) | RU2610427C2 (cg-RX-API-DMAC7.html) |
| SG (2) | SG10201403758SA (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011004264A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060045872A1 (en) | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
| PT1926813T (pt) | 2005-09-23 | 2016-09-06 | Consejo Superior Investigacion | Populações de células que têm atividade imunorreguladora, método para isolamento e usos |
| US11090363B2 (en) | 2009-07-10 | 2021-08-17 | University of Pittsburgh—of the Commonwealth System of Higher Education | Vasoactive intestinal peptide release from microparticles |
| WO2011006029A1 (en) | 2009-07-10 | 2011-01-13 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Artificial cell constructs for inducing immunological tolerance |
| US20140154274A1 (en) * | 2011-01-12 | 2014-06-05 | Tigenix Nv | Methods and compositions for use in intralymphatic cellular therapies |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| CN104136034B (zh) | 2011-11-30 | 2018-04-24 | 安斯泰来再生医药协会 | 间充质基质细胞及其相关用途 |
| EP2833896A2 (en) * | 2012-03-30 | 2015-02-11 | University Of Southern California | Compositions and treatment methods for mesenchymal stem cell-induced immunoregulation |
| CN104471059B (zh) | 2012-07-12 | 2018-04-17 | 珠海横琴爱姆斯坦生物科技有限公司 | 人胚胎干细胞衍生的间充质样干细胞、方法及其应用 |
| WO2016098061A1 (en) | 2014-12-18 | 2016-06-23 | Pluristem Ltd. | Methods and compositions for treating and preventing muscle wasting disorders |
| WO2016107563A1 (zh) * | 2014-12-29 | 2016-07-07 | 西比曼生物科技（上海）有限公司 | 一种用于治疗上呼吸道疾病的脂肪间充质祖细胞复合物 |
| US20180015125A1 (en) | 2015-03-23 | 2018-01-18 | Pluristem Ltd. | Use of adherent stromal cells for enhancing hematopoiesis in a subject in need thereof |
| JP6884792B2 (ja) | 2016-02-18 | 2021-06-09 | プルリステム リミテッド | がん及び新生物の治療方法及び治療用組成物 |
| GB201604304D0 (en) | 2016-03-14 | 2016-04-27 | Tigenix S A U | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| US12161688B2 (en) | 2016-06-30 | 2024-12-10 | Mapi Pharma Ltd | Treatment of inflammatory bowel disease with long acting glatiramer and adipose-derived stem cells |
| IL269893B2 (en) | 2017-05-15 | 2023-10-01 | Stem Cell Medicine Ltd | Treatment of multiple sclerosis with adipose-derived stem cells |
| CA3062964C (en) | 2017-05-15 | 2024-11-12 | Mapi Pharma Ltd. | TREATMENT OF MULTIPLE SCLEROSIS WITH A LONG-ACTING GLATIRAMER AND ADIPE-DERIVED STEM CELLS |
| CN107349419A (zh) * | 2017-07-17 | 2017-11-17 | 广东颜值科技有限公司 | 一种细胞组合物及其制备方法和应用 |
| CN107281469A (zh) * | 2017-07-17 | 2017-10-24 | 广东颜值科技有限公司 | 一种细胞组合物及其制备方法和应用 |
| US12268714B2 (en) | 2018-09-14 | 2025-04-08 | Luca Science Inc. | Transplantation of mitochondria into lymphoid organ and composition therefor |
| JP2022527455A (ja) * | 2019-03-19 | 2022-06-02 | フィジーン、エルエルシー | 活性化線維芽細胞及びそのエキソソーム誘導体を用いた慢性閉塞性肺疾患及び肺変性の治療 |
| EP3976032A4 (en) * | 2019-05-31 | 2023-06-14 | Figene, LLC | SIMULTANEOUS ACTIVATION OF REGENERATIVE AND TOLEROGENIC PROCESSES BY COMPOSITIONS BASED ON FIBROBLASTS IN THE TREATMENT OF MULTIPLE SCLEROSIS |
| US20240000850A1 (en) * | 2020-04-08 | 2024-01-04 | Figene, Llc | Methods and compositions for allergy and asthma treatment using fibroblasts |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1551449B1 (en) * | 2002-07-12 | 2010-10-06 | The Johns Hopkins University | Reagents and methods for engaging unique clonotypic lymphocyte receptors |
| CN1738619B (zh) * | 2002-12-06 | 2012-04-18 | 西北生物治疗药物公司 | 给予体外部分成熟的树突细胞治疗肿瘤的制药用途 |
| PT1926813T (pt) | 2005-09-23 | 2016-09-06 | Consejo Superior Investigacion | Populações de células que têm atividade imunorreguladora, método para isolamento e usos |
| US8241621B2 (en) * | 2006-12-18 | 2012-08-14 | Medistem Laboratories | Stem cell mediated treg activation/expansion for therapeutic immune modulation |
| EP2581441A1 (en) * | 2007-08-09 | 2013-04-17 | Genzyme Corporation | Method of treating autoimmune disease with mesenchymal stem cells |
| EP2191835A4 (en) * | 2007-09-07 | 2011-12-14 | Japan Chem Res | THERAPEUTIC AND PROPHYLACTIC AGENTS FOR ARTHRITIS |
| WO2009134429A2 (en) * | 2008-05-02 | 2009-11-05 | Massachusetts Institute Of Technology | Methods and compositions for modulating immunological tolerance |
| GB0814249D0 (en) * | 2008-08-04 | 2008-09-10 | Cellerix Sa | Uses of mesenchymal stem cells |
-
2010
- 2010-07-09 US US13/382,426 patent/US8679834B2/en active Active
- 2010-07-09 BR BR112012000534A patent/BR112012000534A2/pt not_active Application Discontinuation
- 2010-07-09 AU AU2010269962A patent/AU2010269962B2/en active Active
- 2010-07-09 CA CA2767300A patent/CA2767300C/en active Active
- 2010-07-09 RU RU2012104529A patent/RU2610427C2/ru active
- 2010-07-09 NZ NZ597975A patent/NZ597975A/en unknown
- 2010-07-09 CN CN201710067652.0A patent/CN107007626A/zh active Pending
- 2010-07-09 ES ES10752171.8T patent/ES2479542T3/es active Active
- 2010-07-09 SG SG10201403758SA patent/SG10201403758SA/en unknown
- 2010-07-09 SG SG2012001574A patent/SG177582A1/en unknown
- 2010-07-09 JP JP2012519080A patent/JP5892931B2/ja active Active
- 2010-07-09 KR KR1020127003364A patent/KR101788885B1/ko active Active
- 2010-07-09 HU HUE10752171A patent/HUE031921T2/en unknown
- 2010-07-09 PL PL10752171T patent/PL2451943T3/pl unknown
- 2010-07-09 CN CN2010800308900A patent/CN102549147A/zh active Pending
- 2010-07-09 EP EP10752171.8A patent/EP2451943B1/en active Active
- 2010-07-09 PT PT107521718T patent/PT2451943T/pt unknown
- 2010-07-09 MX MX2012000396A patent/MX359639B/es active IP Right Grant
- 2010-07-09 WO PCT/IB2010/001968 patent/WO2011004264A1/en not_active Ceased
- 2010-07-09 DK DK10752171.8T patent/DK2451943T3/en active
- 2010-07-09 EP EP16199980.0A patent/EP3150703A1/en not_active Withdrawn
-
2012
- 2012-01-05 IL IL217377A patent/IL217377A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| IL217377A (en) | 2017-10-31 |
| DK2451943T3 (en) | 2017-02-06 |
| PL2451943T3 (pl) | 2017-04-28 |
| KR20120051006A (ko) | 2012-05-21 |
| WO2011004264A1 (en) | 2011-01-13 |
| JP2012532859A (ja) | 2012-12-20 |
| ES2479542T1 (es) | 2014-08-20 |
| RU2012104529A (ru) | 2013-08-20 |
| CN102549147A (zh) | 2012-07-04 |
| EP3150703A1 (en) | 2017-04-05 |
| KR101788885B1 (ko) | 2017-10-20 |
| JP5892931B2 (ja) | 2016-03-23 |
| RU2610427C2 (ru) | 2017-02-10 |
| MX2012000396A (es) | 2012-07-17 |
| IL217377A0 (en) | 2012-02-29 |
| HUE031921T2 (en) | 2017-08-28 |
| NZ597975A (en) | 2014-06-27 |
| CA2767300A1 (en) | 2011-01-13 |
| MX359639B (es) | 2018-10-04 |
| ES2479542T3 (es) | 2017-05-26 |
| US8679834B2 (en) | 2014-03-25 |
| US20120308585A1 (en) | 2012-12-06 |
| AU2010269962B2 (en) | 2016-04-14 |
| EP2451943B1 (en) | 2016-11-23 |
| CA2767300C (en) | 2020-01-07 |
| BR112012000534A2 (pt) | 2017-06-13 |
| PT2451943T (pt) | 2017-01-20 |
| AU2010269962A1 (en) | 2012-03-01 |
| EP2451943A1 (en) | 2012-05-16 |
| CN107007626A (zh) | 2017-08-04 |
| SG177582A1 (en) | 2012-03-29 |
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