SG10201401643PA - Methods for assessing cytotoxicity of single cells - Google Patents
Methods for assessing cytotoxicity of single cellsInfo
- Publication number
- SG10201401643PA SG10201401643PA SG10201401643PA SG10201401643PA SG10201401643PA SG 10201401643P A SG10201401643P A SG 10201401643PA SG 10201401643P A SG10201401643P A SG 10201401643PA SG 10201401643P A SG10201401643P A SG 10201401643PA SG 10201401643P A SG10201401643P A SG 10201401643PA
- Authority
- SG
- Singapore
- Prior art keywords
- methods
- single cells
- assessing cytotoxicity
- cytotoxicity
- assessing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/563—Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/06—Methods of screening libraries by measuring effects on living organisms, tissues or cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
- G01N2333/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
- G01N2333/16—HIV-1, HIV-2
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14610609P | 2009-01-21 | 2009-01-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201401643PA true SG10201401643PA (en) | 2014-08-28 |
Family
ID=42356144
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2011049459A SG172889A1 (en) | 2009-01-21 | 2009-07-13 | Compositions and methods for assessing cytotoxicity of single cells |
| SG10201401643PA SG10201401643PA (en) | 2009-01-21 | 2009-07-13 | Methods for assessing cytotoxicity of single cells |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2011049459A SG172889A1 (en) | 2009-01-21 | 2009-07-13 | Compositions and methods for assessing cytotoxicity of single cells |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9244071B2 (ja) |
| EP (1) | EP2389446B1 (ja) |
| JP (2) | JP2012515548A (ja) |
| KR (1) | KR20110134386A (ja) |
| CN (2) | CN104745669A (ja) |
| AU (1) | AU2009338127B2 (ja) |
| CA (1) | CA2689681C (ja) |
| IL (1) | IL213938A0 (ja) |
| RU (1) | RU2532228C2 (ja) |
| SG (2) | SG172889A1 (ja) |
| WO (1) | WO2010085275A1 (ja) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9404924B2 (en) | 2008-12-04 | 2016-08-02 | Massachusetts Institute Of Technology | Method of performing one-step, single cell RT-PCR |
| US9244080B2 (en) | 2008-12-04 | 2016-01-26 | Massachussetts Institute Of Technology | Method for diagnosing allergic reactions |
| SG172889A1 (en) | 2009-01-21 | 2011-08-29 | Massachusetts Inst Technology | Compositions and methods for assessing cytotoxicity of single cells |
| US9891157B2 (en) | 2010-12-03 | 2018-02-13 | Cellply S.R.L. | Microanalysis of cellular function |
| WO2012072823A1 (en) * | 2010-12-03 | 2012-06-07 | Mindseeds Laboratories Srl | Rapid screening of monoclonal antibodies |
| EP2791358B1 (en) | 2011-12-13 | 2017-06-14 | Single Cell Technology, Inc. | Method of screening a plurality of single secreting cells for functional activity |
| US20150191772A1 (en) | 2012-06-29 | 2015-07-09 | Danmarks Tekniske Universitet | Method of charging a test carrier and a test carrier |
| CN104884605B (zh) * | 2012-08-24 | 2018-05-18 | 耶鲁大学 | 用于高通量多重检测的系统、装置和方法 |
| WO2015031190A1 (en) * | 2013-08-26 | 2015-03-05 | President And Fellows Of Harvard College | Determination of immune cells and other cells |
| BR122022010122B1 (pt) | 2014-01-31 | 2023-05-16 | Agbiome, Inc | Composição, uso da composição, método para controlar um patógeno vegetal, formulação para o controle de um patógeno vegetal, uso da formulação, método para cultivar uma planta e uso de um agente de controle biológico nrrl n° b-50897 |
| US9877486B2 (en) | 2014-01-31 | 2018-01-30 | AgBiome, Inc. | Methods of growing plants using modified biological control agents |
| CN107407638B (zh) | 2014-12-03 | 2021-01-12 | 伊索普莱西斯公司 | 细胞分泌特征的分析和筛选 |
| WO2016149639A1 (en) | 2015-03-19 | 2016-09-22 | The Board Of Trustees Of The Leland Stanford Junior University | Devices and methods for high-throughput single cell and biomolecule analysis and retrieval in a microfluidic chip |
| WO2016154620A1 (en) | 2015-03-26 | 2016-09-29 | University Of Houston System | Integrated functional and molecular profiling of cells |
| EP3402902B1 (en) | 2016-01-15 | 2021-10-27 | Massachusetts Institute Of Technology | Semi-permeable arrays for analyzing biological systems and methods of using same |
| CN108779427A (zh) * | 2016-03-30 | 2018-11-09 | 索尼公司 | 细胞观察装置、用于评估免疫细胞活性水平的方法以及用于控制免疫细胞品质的方法 |
| US10569270B2 (en) | 2016-06-14 | 2020-02-25 | Cellply S.R.L. | Screening kit and method |
| CN106086171A (zh) * | 2016-06-15 | 2016-11-09 | 广州中大南沙科技创新产业园有限公司 | 一种抑制肿瘤细胞增殖的药物筛选方法 |
| CN109563539A (zh) | 2016-06-15 | 2019-04-02 | 慕尼黑路德维希马克西米利安斯大学 | 使用dna纳米技术的单分子检测或定量 |
| CA3041109A1 (en) * | 2016-10-19 | 2018-04-26 | General Automation Lab Technologies Inc. | High resolution systems, kits, apparatus, and methods for screening microorganisms and other high throughput microbiology applications |
| WO2018089910A2 (en) * | 2016-11-11 | 2018-05-17 | IsoPlexis Corporation | Compositions and methods for the simultaneous genomic, transcriptomic and proteomic analysis of single cells |
| US11085912B2 (en) * | 2016-12-14 | 2021-08-10 | University Of Cincinnati | Methods of diagnosing Clostridium difficile infection or recurrence in a subject |
| SE543211C2 (en) | 2017-06-29 | 2020-10-27 | Mabtech Production Ab | Method and system for analyzing Fluorospot assays |
| EP3720605A1 (en) | 2017-12-07 | 2020-10-14 | Massachusetts Institute Of Technology | Single cell analyses |
| CN108728356B (zh) * | 2018-05-23 | 2022-02-22 | 北京科技大学 | 用于不同三维细胞团配对的装置及共培养方法 |
| WO2020147035A1 (en) * | 2019-01-16 | 2020-07-23 | Yantai Ausbio Laboratories Co., Ltd. | Automated liquid handling system and method for depositing biological samples for microscopic examination |
| KR20210128444A (ko) | 2019-02-18 | 2021-10-26 | 가부시키가이샤 에누비 켄코우겡큐쇼 | 세포의 선발 방법, 핵산의 제조 방법, 재조합 세포의 제조 방법, 목적 물질의 제조 방법, 의약 조성물의 제조 방법, 및 시약 |
| US12064768B2 (en) | 2020-02-21 | 2024-08-20 | Northeastern University | Single cell isolation and processing system with reversible well shape |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL68507A (en) | 1982-05-10 | 1986-01-31 | Univ Bar Ilan | System and methods for cell selection |
| SU1650094A1 (ru) * | 1987-12-29 | 1991-05-23 | Научно-исследовательский институт проктологии | Способ диагностики прот женности активного воспалени в толстой кишке при неспецифическом звенном колите |
| US6410252B1 (en) | 1995-12-22 | 2002-06-25 | Case Western Reserve University | Methods for measuring T cell cytokines |
| US6210910B1 (en) | 1998-03-02 | 2001-04-03 | Trustees Of Tufts College | Optical fiber biosensor array comprising cell populations confined to microcavities |
| WO2000061629A1 (en) * | 1999-04-09 | 2000-10-19 | Human Genome Sciences, Inc. | 49 human secreted proteins |
| EP1192176A4 (en) * | 1999-06-11 | 2003-03-05 | Human Genome Sciences Inc | 49 HUMAN SECRETED PROTEINS |
| US7332286B2 (en) | 2001-02-02 | 2008-02-19 | University Of Pennsylvania | Peptide or protein microassay method and apparatus |
| US20020141906A1 (en) | 2001-03-30 | 2002-10-03 | American Type Culture Collection | Microtiter plate sealing cover with well identifiers |
| WO2007035633A2 (en) * | 2005-09-16 | 2007-03-29 | President & Fellows Of Harvard College | Screening assays and methods |
| WO2009145925A1 (en) | 2008-05-30 | 2009-12-03 | Massachusetts Institute Of Technology | Compositions and methods for spatial separation and screening of cells |
| US9404924B2 (en) | 2008-12-04 | 2016-08-02 | Massachusetts Institute Of Technology | Method of performing one-step, single cell RT-PCR |
| US9244080B2 (en) | 2008-12-04 | 2016-01-26 | Massachussetts Institute Of Technology | Method for diagnosing allergic reactions |
| SG172889A1 (en) | 2009-01-21 | 2011-08-29 | Massachusetts Inst Technology | Compositions and methods for assessing cytotoxicity of single cells |
| US8569046B2 (en) | 2009-02-20 | 2013-10-29 | Massachusetts Institute Of Technology | Microarray with microchannels |
-
2009
- 2009-07-13 SG SG2011049459A patent/SG172889A1/en unknown
- 2009-07-13 WO PCT/US2009/050411 patent/WO2010085275A1/en active Application Filing
- 2009-07-13 CN CN201510140107.0A patent/CN104745669A/zh active Pending
- 2009-07-13 RU RU2011134898/10A patent/RU2532228C2/ru not_active IP Right Cessation
- 2009-07-13 AU AU2009338127A patent/AU2009338127B2/en not_active Ceased
- 2009-07-13 SG SG10201401643PA patent/SG10201401643PA/en unknown
- 2009-07-13 EP EP09839012.3A patent/EP2389446B1/en not_active Not-in-force
- 2009-07-13 JP JP2011547913A patent/JP2012515548A/ja not_active Withdrawn
- 2009-07-13 US US13/145,300 patent/US9244071B2/en active Active
- 2009-07-13 KR KR1020117018895A patent/KR20110134386A/ko not_active Application Discontinuation
- 2009-07-13 CN CN2009801551526A patent/CN102388145A/zh active Pending
- 2009-07-13 CA CA2689681A patent/CA2689681C/en not_active Expired - Fee Related
-
2011
- 2011-07-05 IL IL213938A patent/IL213938A0/en unknown
-
2015
- 2015-05-05 JP JP2015094509A patent/JP6017620B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2011134898A (ru) | 2013-02-27 |
| RU2532228C2 (ru) | 2014-10-27 |
| SG172889A1 (en) | 2011-08-29 |
| AU2009338127A1 (en) | 2011-07-28 |
| WO2010085275A1 (en) | 2010-07-29 |
| CN104745669A (zh) | 2015-07-01 |
| US9244071B2 (en) | 2016-01-26 |
| US20120149592A1 (en) | 2012-06-14 |
| KR20110134386A (ko) | 2011-12-14 |
| JP2012515548A (ja) | 2012-07-12 |
| IL213938A0 (en) | 2011-07-31 |
| EP2389446B1 (en) | 2017-07-05 |
| EP2389446A1 (en) | 2011-11-30 |
| EP2389446A4 (en) | 2012-10-03 |
| JP6017620B2 (ja) | 2016-11-02 |
| JP2015144617A (ja) | 2015-08-13 |
| CA2689681C (en) | 2017-08-29 |
| CA2689681A1 (en) | 2010-07-21 |
| AU2009338127B2 (en) | 2015-11-26 |
| CN102388145A (zh) | 2012-03-21 |
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