SE9500342D0 - Novel chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation - Google Patents

Novel chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation

Info

Publication number
SE9500342D0
SE9500342D0 SE9500342A SE9500342A SE9500342D0 SE 9500342 D0 SE9500342 D0 SE 9500342D0 SE 9500342 A SE9500342 A SE 9500342A SE 9500342 A SE9500342 A SE 9500342A SE 9500342 D0 SE9500342 D0 SE 9500342D0
Authority
SE
Sweden
Prior art keywords
nucleic acid
group
compounds
optionally
acid sequencing
Prior art date
Application number
SE9500342A
Other languages
English (en)
Swedish (sv)
Inventor
Marek Kwiatkowski
Original Assignee
Marek Kwiatkowski
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marek Kwiatkowski filed Critical Marek Kwiatkowski
Priority to SE9500342A priority Critical patent/SE9500342D0/xx
Publication of SE9500342D0 publication Critical patent/SE9500342D0/xx
Priority to DE69627314T priority patent/DE69627314T2/de
Priority to PCT/SE1996/000096 priority patent/WO1996023807A1/fr
Priority to JP8523466A priority patent/JPH10513178A/ja
Priority to CA002212000A priority patent/CA2212000A1/fr
Priority to US08/875,243 priority patent/US6255475B1/en
Priority to ES96902039T priority patent/ES2197231T3/es
Priority to EP96902039A priority patent/EP0808320B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE9500342A 1995-01-31 1995-01-31 Novel chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation SE9500342D0 (sv)

Priority Applications (8)

Application Number Priority Date Filing Date Title
SE9500342A SE9500342D0 (sv) 1995-01-31 1995-01-31 Novel chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation
DE69627314T DE69627314T2 (de) 1995-01-31 1996-01-30 Kettenabbruchgruppen, ihre verwendung zur sequenzierung und synthese von nukleinsäuren und verfahren zu ihrer herstellung
PCT/SE1996/000096 WO1996023807A1 (fr) 1995-01-31 1996-01-30 Nouveaux agents terminateurs de chaines, leur utilisation pour le sequençage et la synthese d'acides nucleiques, et procede pour les preparer
JP8523466A JPH10513178A (ja) 1995-01-31 1996-01-30 新規な鎖停止剤、核酸配列決定および合成用のその使用、ならびにその製法
CA002212000A CA2212000A1 (fr) 1995-01-31 1996-01-30 Nouveaux agents terminateurs de chaines, leur utilisation pour le sequencage et la synthese d'acides nucleiques, et procede pour les preparer
US08/875,243 US6255475B1 (en) 1995-01-31 1996-01-30 Chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation
ES96902039T ES2197231T3 (es) 1995-01-31 1996-01-30 Nuevos terminadores de cadena, su uso en la secuenciacion y sintesis de acidos nucleicos y metodo para su preparacion.
EP96902039A EP0808320B1 (fr) 1995-01-31 1996-01-30 Nouveaux agents terminateurs de chaines, leur utilisation pour le sequen age et la synthese d'acides nucleiques, et procede pour les preparer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9500342A SE9500342D0 (sv) 1995-01-31 1995-01-31 Novel chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation

Publications (1)

Publication Number Publication Date
SE9500342D0 true SE9500342D0 (sv) 1995-01-31

Family

ID=20397031

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9500342A SE9500342D0 (sv) 1995-01-31 1995-01-31 Novel chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation

Country Status (8)

Country Link
US (1) US6255475B1 (fr)
EP (1) EP0808320B1 (fr)
JP (1) JPH10513178A (fr)
CA (1) CA2212000A1 (fr)
DE (1) DE69627314T2 (fr)
ES (1) ES2197231T3 (fr)
SE (1) SE9500342D0 (fr)
WO (1) WO1996023807A1 (fr)

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US6309836B1 (en) 1999-10-05 2001-10-30 Marek Kwiatkowski Compounds for protecting hydroxyls and methods for their use
EP1244782A2 (fr) * 1999-12-23 2002-10-02 Axaron Bioscience AG Procede de sequen age parallele d'un melange d'acides nucleiques sur une surface
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US9708358B2 (en) 2000-10-06 2017-07-18 The Trustees Of Columbia University In The City Of New York Massive parallel method for decoding DNA and RNA
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US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
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EP2272983A1 (fr) * 2005-02-01 2011-01-12 AB Advanced Genetic Analysis Corporation Réactifs, méthodes et bibliothèques pour séquencage fondé sur des billes
EP2241637A1 (fr) 2005-02-01 2010-10-20 AB Advanced Genetic Analysis Corporation Sequençage nucléotidique comprenant des cycles successifs de formation duplex
GB0517097D0 (en) * 2005-08-19 2005-09-28 Solexa Ltd Modified nucleosides and nucleotides and uses thereof
US7666593B2 (en) 2005-08-26 2010-02-23 Helicos Biosciences Corporation Single molecule sequencing of captured nucleic acids
EP1937849B1 (fr) * 2005-10-27 2019-05-29 The President and Fellows of Harvard College Méthodes et compositions de marquage d'acides nucléiques
US7982029B2 (en) 2005-10-31 2011-07-19 The Trustees Of Columbia University In The City Of New York Synthesis of four color 3′O-allyl, modified photocleavable fluorescent nucleotides and related methods
US8796432B2 (en) 2005-10-31 2014-08-05 The Trustees Of Columbia University In The City Of New York Chemically cleavable 3'-o-allyl-DNTP-allyl-fluorophore fluorescent nucleotide analogues and related methods
US8114636B2 (en) * 2006-02-10 2012-02-14 Life Technologies Corporation Labeling and detection of nucleic acids
WO2008029281A2 (fr) 2006-02-10 2008-03-13 Invitrogen Corporation Marquage et détection de protéines modifiées post-traductionnellement
EP1989242B1 (fr) * 2006-02-21 2010-07-21 Huntsman International Llc Procédé servant à fabriquer un composite de polyisocyanurate
FI20065162A0 (fi) * 2006-03-13 2006-03-13 Wallac Oy Terminoivia DNA polymeraasisubstraatteja
US7482444B2 (en) * 2006-03-13 2009-01-27 Wallac Oy Terminating substrates for DNA polymerases
CN101495654A (zh) * 2006-04-19 2009-07-29 阿普里拉股份有限公司 无凝胶珠基测序的试剂、方法和文库
WO2008042067A2 (fr) 2006-09-28 2008-04-10 Illumina, Inc. Compositions et procédés de séquencage nucléotidique
US7883869B2 (en) 2006-12-01 2011-02-08 The Trustees Of Columbia University In The City Of New York Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators
EP2201021A4 (fr) 2007-08-29 2012-01-25 Applied Biosystems Llc Procédé de séquençage alternatif d'acide nucléique
EP3431615A3 (fr) 2007-10-19 2019-02-20 The Trustees of Columbia University in the City of New York Séquençage d'adn avec des terminateurs nucléotidiques réversibles non fluorescents et terminateurs nucléotidiques modifiées à étiquette clivable
EP2207900B1 (fr) 2007-10-19 2015-04-29 The Trustees of Columbia University in the City of New York Conception et synthèse de nucléotides fluorescents clivables en tant que terminateurs réversibles pour le séquençage de l'adn par synthèse
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Also Published As

Publication number Publication date
ES2197231T3 (es) 2004-01-01
EP0808320B1 (fr) 2003-04-09
US6255475B1 (en) 2001-07-03
CA2212000A1 (fr) 1996-08-08
WO1996023807A1 (fr) 1996-08-08
DE69627314T2 (de) 2004-03-04
EP0808320A1 (fr) 1997-11-26
DE69627314D1 (de) 2003-05-15
JPH10513178A (ja) 1998-12-15

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