SE9202266D0 - Novel piperazine carboxamides - Google Patents

Novel piperazine carboxamides

Info

Publication number
SE9202266D0
SE9202266D0 SE9202266A SE9202266A SE9202266D0 SE 9202266 D0 SE9202266 D0 SE 9202266D0 SE 9202266 A SE9202266 A SE 9202266A SE 9202266 A SE9202266 A SE 9202266A SE 9202266 D0 SE9202266 D0 SE 9202266D0
Authority
SE
Sweden
Prior art keywords
pct
nitrogen
methine
sec
different
Prior art date
Application number
SE9202266A
Other languages
English (en)
Swedish (sv)
Inventor
L Abramo
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Priority to SE9202266A priority Critical patent/SE9202266D0/xx
Publication of SE9202266D0 publication Critical patent/SE9202266D0/xx
Priority to AT93916377T priority patent/ATE190973T1/de
Priority to PCT/SE1993/000639 priority patent/WO1994003436A1/en
Priority to PT93916377T priority patent/PT620814E/pt
Priority to CA002141210A priority patent/CA2141210A1/en
Priority to EP93916377A priority patent/EP0620814B1/en
Priority to DK93916377T priority patent/DK0620814T3/da
Priority to NZ254312A priority patent/NZ254312A/en
Priority to AU45953/93A priority patent/AU666212B2/en
Priority to US08/374,797 priority patent/US5574031A/en
Priority to JP50522394A priority patent/JP3418195B2/ja
Priority to ES93916377T priority patent/ES2144009T3/es
Priority to DE69328165T priority patent/DE69328165T2/de
Priority to IL10650293A priority patent/IL106502A/xx
Priority to CN93116827A priority patent/CN1055687C/zh
Priority to ZA935534A priority patent/ZA935534B/xx
Priority to GR20000401315T priority patent/GR3033629T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE9202266A 1992-07-31 1992-07-31 Novel piperazine carboxamides SE9202266D0 (sv)

Priority Applications (17)

Application Number Priority Date Filing Date Title
SE9202266A SE9202266D0 (sv) 1992-07-31 1992-07-31 Novel piperazine carboxamides
DE69328165T DE69328165T2 (de) 1992-07-31 1993-07-22 Neue piperazincarboxamide
DK93916377T DK0620814T3 (da) 1992-07-31 1993-07-22 Hidtil ukendte piperazincarboxamider
AU45953/93A AU666212B2 (en) 1992-07-31 1993-07-22 Novel piprazine carboxamides
PT93916377T PT620814E (pt) 1992-07-31 1993-07-22 Novas carboxamidas de piperazina
CA002141210A CA2141210A1 (en) 1992-07-31 1993-07-22 Novel piperazine carboxamides
EP93916377A EP0620814B1 (en) 1992-07-31 1993-07-22 Novel piprazine carboxamides
AT93916377T ATE190973T1 (de) 1992-07-31 1993-07-22 Neue piperazincarboxamide
NZ254312A NZ254312A (en) 1992-07-31 1993-07-22 1-((2-substituted)ethyl)-(thio)carbamoyl)piperazine derivatives
PCT/SE1993/000639 WO1994003436A1 (en) 1992-07-31 1993-07-22 Novel piprazine carboxamides
US08/374,797 US5574031A (en) 1992-07-31 1993-07-22 Piperazine carboxamides
JP50522394A JP3418195B2 (ja) 1992-07-31 1993-07-22 新規なピペラジンカルボキサミド
ES93916377T ES2144009T3 (es) 1992-07-31 1993-07-22 Nuevas piperazincarboxamidas.
IL10650293A IL106502A (en) 1992-07-31 1993-07-28 Piperazine and 1,4 diazepine carboxamides and pharmaceutical compositions containing them
CN93116827A CN1055687C (zh) 1992-07-31 1993-07-30 新的哌嗪甲酰胺
ZA935534A ZA935534B (en) 1992-07-31 1993-07-30 Piperazine carboxamides
GR20000401315T GR3033629T3 (en) 1992-07-31 2000-06-07 Novel piprazine carboxamides.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9202266A SE9202266D0 (sv) 1992-07-31 1992-07-31 Novel piperazine carboxamides

Publications (1)

Publication Number Publication Date
SE9202266D0 true SE9202266D0 (sv) 1992-07-31

Family

ID=20386860

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9202266A SE9202266D0 (sv) 1992-07-31 1992-07-31 Novel piperazine carboxamides

Country Status (17)

Country Link
US (1) US5574031A (el)
EP (1) EP0620814B1 (el)
JP (1) JP3418195B2 (el)
CN (1) CN1055687C (el)
AT (1) ATE190973T1 (el)
AU (1) AU666212B2 (el)
CA (1) CA2141210A1 (el)
DE (1) DE69328165T2 (el)
DK (1) DK0620814T3 (el)
ES (1) ES2144009T3 (el)
GR (1) GR3033629T3 (el)
IL (1) IL106502A (el)
NZ (1) NZ254312A (el)
PT (1) PT620814E (el)
SE (1) SE9202266D0 (el)
WO (1) WO1994003436A1 (el)
ZA (1) ZA935534B (el)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4533534B2 (ja) 1998-06-19 2010-09-01 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド グリコーゲンシンターゼキナーゼ３のインヒビター
US7045519B2 (en) 1998-06-19 2006-05-16 Chiron Corporation Inhibitors of glycogen synthase kinase 3
KR100443570B1 (ko) * 2001-07-31 2004-08-09 크레아젠 주식회사 재조합 인간 인터루킨-4의 제조방법
US7718802B2 (en) 2001-08-10 2010-05-18 Palatin Technologies, Inc. Substituted melanocortin receptor-specific piperazine compounds
US7732451B2 (en) 2001-08-10 2010-06-08 Palatin Technologies, Inc. Naphthalene-containing melanocortin receptor-specific small molecule
JP2005504043A (ja) 2001-08-10 2005-02-10 パラチン テクノロジーズ インク． 生物学的に活性な金属ペプチド類のペプチド模倣体類
US7354923B2 (en) * 2001-08-10 2008-04-08 Palatin Technologies, Inc. Piperazine melanocortin-specific compounds
US7456184B2 (en) 2003-05-01 2008-11-25 Palatin Technologies Inc. Melanocortin receptor-specific compounds
US7655658B2 (en) 2001-08-10 2010-02-02 Palatin Technologies, Inc. Thieno [2,3-D]pyrimidine-2,4-dione melanocortin-specific compounds
US7727991B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Substituted melanocortin receptor-specific single acyl piperazine compounds
US7968548B2 (en) 2003-05-01 2011-06-28 Palatin Technologies, Inc. Melanocortin receptor-specific piperazine compounds with diamine groups
US7727990B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Melanocortin receptor-specific piperazine and keto-piperazine compounds
US7709484B1 (en) 2004-04-19 2010-05-04 Palatin Technologies, Inc. Substituted melanocortin receptor-specific piperazine compounds
US7834017B2 (en) 2006-08-11 2010-11-16 Palatin Technologies, Inc. Diamine-containing, tetra-substituted piperazine compounds having identical 1- and 4-substituents

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE791501A (fr) * 1971-11-19 1973-05-17 Albert Ag Chem Werke Diamines cycliques n,n'-disubstituees et leur procede de preparation
US4082755A (en) * 1977-02-14 1978-04-04 Janssen Pharmaceutica N.V. 1-[(Diarylmethyl)aminoalkyl]piperidimes
NO154582C (no) * 1978-10-20 1986-11-05 Ferrosan Ab Analogifremgangsmaate for fremstilling av terapeutisk aktive difenyl-dibutylpiperazinkarboksamider.
US4766125A (en) * 1981-06-23 1988-08-23 Janssen Pharmaceutica N.V. N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia
SE8302886D0 (sv) * 1983-05-20 1983-05-20 Ferrosan Ab Intermediates for preparing substituted 1-piperazine-carboxamides and carbothioamides and use thereof
HU196194B (en) * 1986-04-28 1988-10-28 Richter Gedeon Vegyeszet Process for producing new 1-4 disubstituted piperazines and pharmaceuticals comprising the compounds
NZ223847A (en) * 1987-04-01 1989-12-21 Janssen Pharmaceutica Nv Substituted piperazine derivatives and pharmaceutical compositions
US5026853A (en) * 1987-04-01 1991-06-25 Janssen Pharmaceutica N.V. 4-substituted-2(or 3)aminocarbonyl-1-piperazineacetamide
US4880808A (en) * 1987-04-01 1989-11-14 Janssen Pharmaceutica N.V. N-aryl-piperazinealkanamides useful for improving sleep
EP0455789B1 (en) * 1989-11-22 1994-03-16 Janssen Pharmaceutica N.V. Method of preventing or limiting reperfusion damage

Also Published As

Publication number Publication date
IL106502A (en) 1997-08-14
DE69328165D1 (de) 2000-04-27
IL106502A0 (en) 1993-11-15
DK0620814T3 (da) 2000-07-17
NZ254312A (en) 1997-06-24
US5574031A (en) 1996-11-12
PT620814E (pt) 2000-09-29
EP0620814B1 (en) 2000-03-22
ES2144009T3 (es) 2000-06-01
AU4595393A (en) 1994-03-03
ATE190973T1 (de) 2000-04-15
AU666212B2 (en) 1996-02-01
WO1994003436A1 (en) 1994-02-17
CN1055687C (zh) 2000-08-23
GR3033629T3 (en) 2000-10-31
DE69328165T2 (de) 2000-10-05
ZA935534B (en) 1994-02-24
JP3418195B2 (ja) 2003-06-16
JPH08508008A (ja) 1996-08-27
EP0620814A1 (en) 1994-10-26
CN1088579A (zh) 1994-06-29
CA2141210A1 (en) 1994-02-17

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