SE9101433D0 - Recombinant dna sequence and its use - Google Patents

Recombinant dna sequence and its use

Info

Publication number
SE9101433D0
SE9101433D0 SE9101433A SE9101433A SE9101433D0 SE 9101433 D0 SE9101433 D0 SE 9101433D0 SE 9101433 A SE9101433 A SE 9101433A SE 9101433 A SE9101433 A SE 9101433A SE 9101433 D0 SE9101433 D0 SE 9101433D0
Authority
SE
Sweden
Prior art keywords
gram positive
recombinant dna
protein
cell wall
dna sequence
Prior art date
Application number
SE9101433A
Other languages
English (en)
Swedish (sv)
Inventor
Marianne Hansson
Mathias Uhlen
Per-Ake Nygren
Stefan Stahl
Original Assignee
Marianne Hansson
Mathias Uhlen
Nygren Per Ake
Stefan Stahl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marianne Hansson, Mathias Uhlen, Nygren Per Ake, Stefan Stahl filed Critical Marianne Hansson
Priority to SE9101433A priority Critical patent/SE9101433D0/xx
Publication of SE9101433D0 publication Critical patent/SE9101433D0/xx
Priority to AU17899/92A priority patent/AU664841B2/en
Priority to DE69233375T priority patent/DE69233375T2/de
Priority to EP92910363A priority patent/EP0584167B1/fr
Priority to CA002103021A priority patent/CA2103021C/fr
Priority to JP51056892A priority patent/JP3423712B2/ja
Priority to AT92910363T priority patent/ATE270335T1/de
Priority to PCT/SE1992/000304 priority patent/WO1992020805A1/fr
Priority to OA60434A priority patent/OA09866A/en
Priority to US08/629,039 priority patent/US5958736A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445Plasmodium
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/03Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/705Fusion polypeptide containing domain for protein-protein interaction containing a protein-A fusion
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18511Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18522New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/882Staphylococcus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/882Staphylococcus
    • Y10S435/883Staphylococcus aureus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SE9101433A 1991-05-13 1991-05-13 Recombinant dna sequence and its use SE9101433D0 (sv)

Priority Applications (10)

Application Number Priority Date Filing Date Title
SE9101433A SE9101433D0 (sv) 1991-05-13 1991-05-13 Recombinant dna sequence and its use
AU17899/92A AU664841B2 (en) 1991-05-13 1992-05-11 Recombinant DNA coding for signal peptide, selective interacting polypeptide and membrane anchoring sequence
DE69233375T DE69233375T2 (de) 1991-05-13 1992-05-11 Für ein signalpeptid, ein selektiv wechselwirkendes polypeptid und eine membranankersequenz kodierende rekombinante dns
EP92910363A EP0584167B1 (fr) 1991-05-13 1992-05-11 Adn recombine codant pour un peptide signal, polypeptide d'interaction et sequence d'ancrage de membrane
CA002103021A CA2103021C (fr) 1991-05-13 1992-05-11 Adn recombinant codant pour un peptide signal, polypeptide a interaction selective et sequence d'ancrage membranaire
JP51056892A JP3423712B2 (ja) 1991-05-13 1992-05-11 シグナルペプチド、選択的相互作用ポリペプチド及び膜固定配列をコードする組換えdna配列
AT92910363T ATE270335T1 (de) 1991-05-13 1992-05-11 Für ein signalpeptid, ein selektiv wechselwirkendes polypeptid und eine membranankersequenz kodierende rekombinante dns
PCT/SE1992/000304 WO1992020805A1 (fr) 1991-05-13 1992-05-11 Adn recombine codant pour un peptide signal, polypeptide d'interaction et sequence d'ancrage de membrane
OA60434A OA09866A (en) 1991-05-13 1993-11-11 Recombinant DNA coding for signal peptide; selective interacting polypeptide and membrane anchoring sequence.
US08/629,039 US5958736A (en) 1991-05-13 1996-04-08 Recombinant DNA coding for signal peptide, selective interacting polypeptide and membrane anchoring sequence

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9101433A SE9101433D0 (sv) 1991-05-13 1991-05-13 Recombinant dna sequence and its use

Publications (1)

Publication Number Publication Date
SE9101433D0 true SE9101433D0 (sv) 1991-05-13

Family

ID=20382707

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9101433A SE9101433D0 (sv) 1991-05-13 1991-05-13 Recombinant dna sequence and its use

Country Status (10)

Country Link
US (1) US5958736A (fr)
EP (1) EP0584167B1 (fr)
JP (1) JP3423712B2 (fr)
AT (1) ATE270335T1 (fr)
AU (1) AU664841B2 (fr)
CA (1) CA2103021C (fr)
DE (1) DE69233375T2 (fr)
OA (1) OA09866A (fr)
SE (1) SE9101433D0 (fr)
WO (1) WO1992020805A1 (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5821088A (en) * 1990-05-11 1998-10-13 Siga Pharmaceuticals, Inc. Use of gram-positive bacteria to express recombinant proteins
US6737521B1 (en) * 1990-05-11 2004-05-18 The Rockefeller University Delivery and expression of a hybrid surface protein on the surface of gram positive bacteria
CA2131995A1 (fr) * 1992-03-13 1993-09-16 Vincent A. Fischetti Procede de livraison et d'expression d'une proteine de surface hybride a la surface de bacteries gram positives
EP0682710B1 (fr) * 1993-02-10 2003-10-29 Unilever Plc Procede d'isolation utilisant des proteines immobilisees a capacites de fixation specifique
US6740734B1 (en) * 1994-01-14 2004-05-25 Biovitrum Ab Bacterial receptor structures
FR2718452B1 (fr) * 1994-04-06 1996-06-28 Pf Medicament Elément d'immunogène, agent immunogène, composition pharmaceutique et procédé de préparation.
FR2726577B1 (fr) * 1994-11-07 1997-01-31 Pf Medicament Procede d'obtention d'un peptide derive du virus respiratoire syncitial, polypeptide et bacterie l'exprimant, et leurs applications a titre de medicament
FR2726471B1 (fr) * 1994-11-07 1997-01-31 Pf Medicament Procede pour ameliorer l'immunogenicite d'un compose immunogene ou d'un haptene et application a la preparation de vaccins
CN1160469C (zh) 1994-12-09 2004-08-04 帝国大学改革有限公司 基因的鉴定
FR2766192B1 (fr) * 1997-07-17 2001-07-13 Pf Medicament Epitopes du vrs et anticorps les comportant, utiles dans le diagnostic et la therapie
FR2766091A1 (fr) * 1997-07-18 1999-01-22 Transgene Sa Composition antitumorale a base de polypeptide immunogene de localisation cellulaire modifiee
WO2000014240A2 (fr) 1998-09-04 2000-03-16 Creatogen Aktiengesellschaft Mutants attenues de spi2 de salmonelles utilises comme porteurs d'antigenes
GB9910812D0 (en) 1999-05-10 1999-07-07 Microscience Ltd Vaccine composition
EP1377306A1 (fr) * 2001-03-09 2004-01-07 Dyax Corp. Groupes de liaison d'albumine serique
EP2075256A2 (fr) 2002-01-14 2009-07-01 William Herman Ligands ciblés
EP1532173A4 (fr) * 2002-06-14 2006-03-08 Dyax Corp Analyse de proteines
US20040071705A1 (en) * 2002-06-21 2004-04-15 Dyax Corporation Serum protein-associated target-specific ligands and identification method therefor
WO2008127457A2 (fr) * 2006-12-06 2008-10-23 Repligen Corporation Acides nucléiques codant pour la protéine recombinée a
US8017337B2 (en) * 2007-04-19 2011-09-13 Molecular Detection, Inc. Methods, compositions and kits for detection and analysis of antibiotic-resistant bacteria
WO2009158240A1 (fr) 2008-06-16 2009-12-30 Emergent Product Development Uk Limited Vaccins vectorisés de salmonella contre chlamydia et procédés d’utilisation
WO2016197064A1 (fr) 2015-06-04 2016-12-08 Epstein Alan L Immunothérapie des cellules car ciblées par lym-1 et lym-2
JP7196104B2 (ja) 2017-06-05 2022-12-26 リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル 増強された改変ウイルスカプシドタンパク質
AU2020311897A1 (en) 2019-07-08 2022-02-03 Research Institute At Nationwide Children's Hospital Antibody compositions for disrupting biofilms
AU2022358523A1 (en) 2021-09-30 2024-03-14 The Board Of Regents Of The Universityof Texas System Slc13a5 gene therapy vectors and uses thereof
WO2023096996A2 (fr) 2021-11-24 2023-06-01 Research Institute At Nationwide Children's Hospital Hsv chimère exprimant hil21 pour renforcer l'activité immunitaire antitumorale
WO2023102406A1 (fr) 2021-12-01 2023-06-08 The Board Of Regents Of The Univesity Of Texas System Conception de génome de vecteur pour exprimer un transgène cln7 optimisé
WO2023102518A1 (fr) 2021-12-03 2023-06-08 The Board Of Regents Of The University Of Texas System Vecteurs de thérapie génique gna01 et leurs utilisations
WO2023147476A1 (fr) 2022-01-28 2023-08-03 The Board Of Regents Of The University Of Texas System Cassette transgénique conçue pour exprimer le gène fmr1 humain à codons optimisés

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0109861A3 (fr) * 1982-11-23 1986-05-14 Bio-Response Inc. Procédé pour isoler des cellules
US5200327A (en) * 1985-11-06 1993-04-06 Cangene Corporation Expression system for the secretion of bioactive human granulocyte macrophage colony stimulating factor (GM-CSF) and other heterologous proteins from streptomyces
US4859609A (en) * 1986-04-30 1989-08-22 Genentech, Inc. Novel receptors for efficient determination of ligands and their antagonists or agonists
DE3852304T3 (de) * 1987-03-02 1999-07-01 Enzon Lab Inc Organismus als Träger für "Single Chain Antibody Domain (SCAD)".
DE3744595A1 (de) * 1987-12-31 1989-07-13 Andreas Dr Plueckthun Verfahren zur gentechnischen herstellung von antikoerpern
WO1989007140A1 (fr) * 1988-02-05 1989-08-10 Commonwealth Scientific And Industrial Research Or Systeme d'expression par genes (en particulier pour la proteine de rotavirus vp7) employant un peptide de signal etranger et eventuellement une sequence d'ancrage transmembrane

Also Published As

Publication number Publication date
WO1992020805A1 (fr) 1992-11-26
CA2103021C (fr) 2000-07-04
EP0584167B1 (fr) 2004-06-30
US5958736A (en) 1999-09-28
AU664841B2 (en) 1995-12-07
EP0584167A1 (fr) 1994-03-02
ATE270335T1 (de) 2004-07-15
JP3423712B2 (ja) 2003-07-07
CA2103021A1 (fr) 1992-12-01
AU1789992A (en) 1992-12-30
JPH07502640A (ja) 1995-03-23
OA09866A (en) 1994-08-15
DE69233375D1 (de) 2004-08-05
DE69233375T2 (de) 2005-07-14

Similar Documents

Publication Publication Date Title
SE9101433D0 (sv) Recombinant dna sequence and its use
EP1092774A3 (fr) Antigène de Borrelia burgdorferi OspA, gène le codant et leur utilisations
HK1013847A1 (en) Gdf-1 and uog-1 proteins
DE69333802D1 (de) Äusseres membranprotein von haemophilus
ZA91134B (en) New proteins produced by human lymphocytes,dna sequence encoding these proteins and their pharmaceutical and biological uses
AU3664695A (en) Infective protein delivery system
HUP0001650A2 (hu) Javított expressziós vektorok
NO864759D0 (no) Eutaryotiske fusjonsproteiner, fremstilling og anvendelse derav samt middel til gjennomfoering av fremgangsmaaten.
EP0539530A4 (en) Purification directed cloning of peptides.
AU3192889A (en) T cell activation markers
DK0531300T3 (da) Variant-CD44-overfladeproteiner, DNA-sekvenser, som koder herfor, antistoffer mod disse proteiner samt deres anvendelse til diagnostik og terapi
EP0383837A4 (en) Alveolar surfactant proteins
DK0614980T3 (da) Trans-dominante TAT-varianter fra humant immundeficiens-virus
CA2083177A1 (fr) Proteines surfactantes alveolaires
ES8704207A1 (es) Procedimiento para preparar una molecula de adn
DE3881023D1 (de) Proteine, expressionsvektoren, die fuer solche proteine kodierende dna enthalten und zellen, die solche expressionsvektoren enthalten.
AU7873798A (en) N-terminally extended proteins expressed in yeast
AU5776799A (en) Modified hcv peptide vaccines
DE69634757D1 (de) Vektor zur expression von n-terminal verlängerten proteinen in hefezellen
ES2012283A6 (es) Procedimiento de obtencion de una proteina de endotoxina de efecto insecticida.
CA2163805A1 (fr) Nouveau facteur d'activation des leucocytes
EP0345792A3 (fr) Protéines fusionnées HTLV-I/HIV-I
WO1999055862A3 (fr) Proteines humaines comportant des domaines transmembranaires et sequences d'adn codant ces proteines
Tekamp-Olson Expression and secretion of heterologous proteins in yeast employing truncated alpha-factor leader sequences
EP0953642A4 (fr) Proteine antigenique tirant son origine du virus de la laryngo-tracheite infectieuse