SE8804628A - - Google Patents

Info

Publication number
SE8804628A
SE8804628A SE8804628A SE8804628A SE8804628A SE 8804628 A SE8804628 A SE 8804628A SE 8804628 A SE8804628 A SE 8804628A SE 8804628 A SE8804628 A SE 8804628A SE 8804628 A SE8804628 A SE 8804628A
Authority
SE
Sweden
Prior art keywords
compound
sulfinyl
benzimidazole
pyridinyl
dimethoxy
Prior art date
Application number
SE8804628A
Other languages
English (en)
Other versions
SE8804628D0 (sv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to SE19888804628A priority Critical patent/SE8804628D0/xx
Publication of SE8804628D0 publication Critical patent/SE8804628D0/xx
Publication of SE8804628A publication Critical patent/SE8804628A/xx
Priority to IE404989A priority patent/IE64850B1/xx
Priority to IL9279789A priority patent/IL92797A/en
Priority to PH39730A priority patent/PH27257A/en
Priority to GR890100834A priority patent/GR1000318B/el
Priority to CA002005987A priority patent/CA2005987C/en
Priority to ZA899796A priority patent/ZA899796B/xx
Priority to AU48176/90A priority patent/AU636866B2/en
Priority to DD89335979A priority patent/DD296077A5/de
Priority to DE68917738T priority patent/DE68917738T2/de
Priority to EP90901080A priority patent/EP0451188B1/en
Priority to RO147868A priority patent/RO110496B1/ro
Priority to SU894895822A priority patent/RU2070199C1/ru
Priority to PCT/SE1989/000741 priority patent/WO1990006926A1/en
Priority to AT90901080T priority patent/ATE110379T1/de
Priority to US07/454,046 priority patent/US5019584A/en
Priority to JP2501538A priority patent/JP2793907B2/ja
Priority to HU901085A priority patent/HUT57203A/hu
Priority to CN89109588A priority patent/CN1028232C/zh
Priority to YU02425/89A priority patent/YU242589A/xx
Priority to PT92647A priority patent/PT92647B/pt
Priority to FI913036A priority patent/FI913036A0/fi
Priority to NO912416A priority patent/NO178338C/no
Priority to NO912415A priority patent/NO178337C/no
Priority to DK122391A priority patent/DK170801B1/da
Priority to LVP-93-692A priority patent/LV10268B/lv
Priority to LTIP1722A priority patent/LT3981B/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE19888804628A 1988-12-22 1988-12-22 New compounds SE8804628D0 (sv)

Priority Applications (27)

Application Number Priority Date Filing Date Title
SE19888804628A SE8804628D0 (sv) 1988-12-22 1988-12-22 New compounds
IE404989A IE64850B1 (en) 1988-12-22 1989-12-18 Therapeutically active substituted benzimidazole and process for its preparation
IL9279789A IL92797A (en) 1988-12-22 1989-12-19 Substituted benzimidazoles, process for their preparation and pharmaceutical compositions containing such compounds
PH39730A PH27257A (en) 1988-12-22 1989-12-19 Therapeutically active chloro substituted benzimidazole
GR890100834A GR1000318B (el) 1988-12-22 1989-12-19 Θεραπευτικως δραστικη υποκατεστημενη βενζιμιδαζολη και μεθοδος για την παρασκευη αυτης.
CA002005987A CA2005987C (en) 1988-12-22 1989-12-19 Therapeutically active substituted benzimidazole and process for its preparation
JP2501538A JP2793907B2 (ja) 1988-12-22 1989-12-20 治療上活性な置換されたベンズイミダゾールおよびその製法
AU48176/90A AU636866B2 (en) 1988-12-22 1989-12-20 Therapeutically active substituted benzimidazole and process for its preparation
RO147868A RO110496B1 (ro) 1988-12-22 1989-12-20 Compus de benzimidazol activ terapeutic, procedeu de preparare, compus intermediar pentru acesta si compozitie farmaceutica ce contine compusul de benzimidazol
HU901085A HUT57203A (en) 1988-12-22 1989-12-20 Process for substituted benzimidazol and paharmaceutical composition containing them
DD89335979A DD296077A5 (de) 1988-12-22 1989-12-20 Verfahren zur herstellung von benzimidazolen
DE68917738T DE68917738T2 (de) 1988-12-22 1989-12-20 Therapeutisch aktive substituierte Benzimidazole und Verfahren zu ihrer Herstellung.
EP90901080A EP0451188B1 (en) 1988-12-22 1989-12-20 Therapeutically active substituted benzimidazole and process for its preparation
ZA899796A ZA899796B (en) 1988-12-22 1989-12-20 Therapeutically active substituted benzimidazole and process for its preparation
SU894895822A RU2070199C1 (ru) 1988-12-22 1989-12-20 5-хлор-2 //([(3,4-диметокси-2-пиридинил)метил] /сульфинил/) - 1н-бензимидазол или его фармацевтически приемлемая соль, способ получения, фармацевтическая композиция и 5-хлор-2 //([(3,4-диметокси-2-пиридинил)метил]тио) - 1н-бензимидазол
PCT/SE1989/000741 WO1990006926A1 (en) 1988-12-22 1989-12-20 Therapeutically active substituted benzimidazole and process for its preparation
AT90901080T ATE110379T1 (de) 1988-12-22 1989-12-20 Therapeutisch aktive substituierte benzimidazole und verfahren zu ihrer herstellung.
US07/454,046 US5019584A (en) 1988-12-22 1989-12-20 Therapeutically active chloro substituted benzimidazole
PT92647A PT92647B (pt) 1988-12-22 1989-12-21 Processo para a preparacao de 5-cloro-2-< { (3,4-dimetoxi-2-piridinil)-metil}-sulfinil>-1h-benzimidazol e de composicoes farmaceuticas que o contem
CN89109588A CN1028232C (zh) 1988-12-22 1989-12-21 具有治疗活性的取代的苯并咪唑的制备方法
YU02425/89A YU242589A (en) 1988-12-22 1989-12-21 New substituted benzimidazole and process for obtaining thereof
FI913036A FI913036A0 (fi) 1988-12-22 1991-06-20 Terapeutiskt aktiv substituerad benzimidazol och foerfarande foer dess framstaellning.
NO912416A NO178338C (no) 1988-12-22 1991-06-20 Analogifremgangsmåte for fremstilling av en terapeutisk aktiv benzimidazolforbindelse samt mellomprodukt
NO912415A NO178337C (no) 1988-12-22 1991-06-20 Analogifremgangsmåte for fremstilling av terapeutisk aktiv 5-fluor-2[[(4-cyklopropyl-(metoksy-2-pyridinyl)metylÅsulfinylÅ-1H-benzimidazol og mellomprodukter
DK122391A DK170801B1 (da) 1988-12-22 1991-06-21 Terapeutisk aktivt, substitueret benzimidazolderivat og fysiologisk acceptable salte og optiske enantiomerer heraf samt fremgangsmåde til fremstilling af samme, farmaceutisk præparat indeholdende benzimidazolderivatet, anvendelse af derivatet til fremstilling af et lægemiddel til hæmning af mavesyresekretionen hos pattedyr og til behandling af inflammatoriske mavetarmkanallidelser hos pattedyr sam
LVP-93-692A LV10268B (en) 1988-12-22 1993-06-28 Therapeutically active substituted benzimidazole and process for its preparation
LTIP1722A LT3981B (en) 1988-12-22 1993-12-30 Therapeutically active substituted benzimidazole and process for its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE19888804628A SE8804628D0 (sv) 1988-12-22 1988-12-22 New compounds

Publications (2)

Publication Number Publication Date
SE8804628A true SE8804628A (es) 1988-12-22
SE8804628D0 SE8804628D0 (sv) 1988-12-22

Family

ID=20374309

Family Applications (1)

Application Number Title Priority Date Filing Date
SE19888804628A SE8804628D0 (sv) 1988-12-22 1988-12-22 New compounds

Country Status (26)

Country Link
US (1) US5019584A (es)
EP (1) EP0451188B1 (es)
JP (1) JP2793907B2 (es)
CN (1) CN1028232C (es)
AT (1) ATE110379T1 (es)
AU (1) AU636866B2 (es)
CA (1) CA2005987C (es)
DD (1) DD296077A5 (es)
DE (1) DE68917738T2 (es)
DK (1) DK170801B1 (es)
FI (1) FI913036A0 (es)
GR (1) GR1000318B (es)
HU (1) HUT57203A (es)
IE (1) IE64850B1 (es)
IL (1) IL92797A (es)
LT (1) LT3981B (es)
LV (1) LV10268B (es)
NO (1) NO178338C (es)
PH (1) PH27257A (es)
PT (1) PT92647B (es)
RO (1) RO110496B1 (es)
RU (1) RU2070199C1 (es)
SE (1) SE8804628D0 (es)
WO (1) WO1990006926A1 (es)
YU (1) YU242589A (es)
ZA (1) ZA899796B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL165898B1 (pl) * 1990-06-20 1995-02-28 Astra Ab Sposób wytwarzania nowych pochodnych dwualkoksyplrydynylobenzlmldazolu PL
NZ244301A (en) * 1991-09-20 1994-08-26 Merck & Co Inc Preparation of 2-pyridylmethylsulphinylbenzimidazole and pyridoimidazole derivatives from the corresponding sulphenyl compounds
US6016044A (en) * 1995-09-11 2000-01-18 Alaris Medical Systems, Inc. Open-loop step motor control system
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6699885B2 (en) * 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
EP1469839A2 (en) * 2002-01-25 2004-10-27 Santarus, Inc. Transmucosal delivery of proton pump inhibitors
AU2003224781A1 (en) * 2002-03-26 2003-10-13 Dr. Reddy's Laboratories Limited Crystalline forms of rabeprazole sodium
CA2517005A1 (en) * 2003-02-20 2004-09-02 Santarus, Inc. A novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
WO2005007117A2 (en) * 2003-07-18 2005-01-27 Santarus, Inc. Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
TWI398273B (zh) * 2003-07-18 2013-06-11 Santarus Inc 用於抑制酸分泌之醫藥調配物及其製備及使用之方法
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (es) 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
US4331671A (en) * 1981-01-09 1982-05-25 Sterling Drug Inc. 5-(Pyridinyl)-1H-benzimidazoles and 1-hydroxy-6-(pyridinyl)-1H-benzimidazoles and their cardiotonic use
HU195220B (en) 1983-05-03 1988-04-28 Byk Gulden Lomberg Chem Fqb Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them
JPS6150979A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS6150978A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
SE8500996D0 (sv) * 1985-03-01 1985-03-01 Haessle Ab Method of treatment
US4738975A (en) * 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
GB8610607D0 (en) * 1986-04-30 1986-06-04 Smith Kline French Lab Chemical compounds
FR2593178B1 (fr) * 1986-01-20 1988-04-29 Esteve Labor Dr Derives de 2-benzimidazolylalkylthio (ou sulfinyle ou sulfonyle) leur preparation et leur application en tant que medicaments.
WO1989003830A1 (en) * 1987-10-30 1989-05-05 Aktiebolaget Hässle 2-pyridinylmethyl (sulfinyl or thio)benzimidazoles for treatment of diseases related to bone loss

Also Published As

Publication number Publication date
LTIP1722A (en) 1995-07-25
DD296077A5 (de) 1991-11-21
CA2005987C (en) 1999-04-13
EP0451188A1 (en) 1991-10-16
CA2005987A1 (en) 1990-06-22
YU242589A (en) 1991-04-30
PT92647B (pt) 1995-09-12
LV10268A (lv) 1994-10-20
CN1028232C (zh) 1995-04-19
EP0451188B1 (en) 1994-08-24
RU2070199C1 (ru) 1996-12-10
GR1000318B (el) 1992-06-25
LV10268B (en) 1995-02-20
NO178338C (no) 1996-03-06
DK170801B1 (da) 1996-01-22
JP2793907B2 (ja) 1998-09-03
GR890100834A (en) 1991-03-15
FI913036A0 (fi) 1991-06-20
IE64850B1 (en) 1995-09-06
CN1043714A (zh) 1990-07-11
IE894049L (en) 1990-06-22
DE68917738D1 (de) 1994-09-29
LT3981B (en) 1996-06-25
NO912416D0 (no) 1991-06-20
AU4817690A (en) 1990-07-10
DK122391A (da) 1991-06-24
HUT57203A (en) 1991-11-28
NO912416L (no) 1991-07-31
HU901085D0 (en) 1991-09-30
US5019584A (en) 1991-05-28
IL92797A (en) 1994-12-29
NO178338B (no) 1995-11-27
ZA899796B (en) 1990-08-29
PT92647A (pt) 1990-06-29
DK122391D0 (da) 1991-06-21
AU636866B2 (en) 1993-05-13
PH27257A (en) 1993-05-04
SE8804628D0 (sv) 1988-12-22
IL92797A0 (en) 1990-09-17
ATE110379T1 (de) 1994-09-15
JPH04502462A (ja) 1992-05-07
DE68917738T2 (de) 1994-12-22
WO1990006926A1 (en) 1990-06-28
RO110496B1 (ro) 1996-01-30

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