SE8404568D0 - Microphase separated hydrogels for controlled release of bioactive materials - Google Patents

Microphase separated hydrogels for controlled release of bioactive materials

Info

Publication number
SE8404568D0
SE8404568D0 SE8404568A SE8404568A SE8404568D0 SE 8404568 D0 SE8404568 D0 SE 8404568D0 SE 8404568 A SE8404568 A SE 8404568A SE 8404568 A SE8404568 A SE 8404568A SE 8404568 D0 SE8404568 D0 SE 8404568D0
Authority
SE
Sweden
Prior art keywords
microphase separated
controlled release
bioactive materials
blend
release
Prior art date
Application number
SE8404568A
Other languages
English (en)
Other versions
SE461502B (sv
SE8404568L (sv
Inventor
K R Shah
Original Assignee
Kendall & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kendall & Co filed Critical Kendall & Co
Publication of SE8404568D0 publication Critical patent/SE8404568D0/sv
Publication of SE8404568L publication Critical patent/SE8404568L/sv
Publication of SE461502B publication Critical patent/SE461502B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L39/00Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions of derivatives of such polymers
    • C08L39/04Homopolymers or copolymers of monomers containing heterocyclic rings having nitrogen as ring member
    • C08L39/06Homopolymers or copolymers of N-vinyl-pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L57/00Compositions of unspecified polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds
SE8404568A 1983-09-15 1984-09-12 Komposition foer reglerad frisaettning av ett vattenloesligt laekemedel fraan en mikrofasseparerad hydrogel SE461502B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53264383A 1983-09-15 1983-09-15
US06/606,794 US4693887A (en) 1983-09-15 1984-05-03 Microphase separated hydrogels for controlled release of bioactive materials

Publications (3)

Publication Number Publication Date
SE8404568D0 true SE8404568D0 (sv) 1984-09-12
SE8404568L SE8404568L (sv) 1985-03-16
SE461502B SE461502B (sv) 1990-02-26

Family

ID=27063895

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8404568A SE461502B (sv) 1983-09-15 1984-09-12 Komposition foer reglerad frisaettning av ett vattenloesligt laekemedel fraan en mikrofasseparerad hydrogel

Country Status (18)

Country Link
US (1) US4693887A (sv)
AT (1) ATA290884A (sv)
AU (1) AU577056B2 (sv)
BE (1) BE900581A (sv)
BR (1) BR8404409A (sv)
CA (1) CA1232201A (sv)
CH (1) CH666415A5 (sv)
DE (1) DE3432573A1 (sv)
DK (1) DK410984A (sv)
ES (1) ES8607357A1 (sv)
FR (1) FR2551976B1 (sv)
GB (2) GB2147002B (sv)
IT (1) IT1178430B (sv)
NL (1) NL8402833A (sv)
NO (1) NO843650L (sv)
NZ (1) NZ209323A (sv)
PT (1) PT79192B (sv)
SE (1) SE461502B (sv)

Families Citing this family (48)

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FR2576213B1 (fr) * 1985-01-21 1989-02-24 Cortial Nouveau procede d'obtention de formes pharmaceutiques a liberation prolongee
US4883669A (en) * 1985-02-25 1989-11-28 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit for estradiol and other estrogenic steroids and process for administration
DE3517080A1 (de) * 1985-05-11 1986-11-13 Bayer Ag, 5090 Leverkusen Komponente fuer therapeutische wirkstoffabgabesysteme
IE59361B1 (en) * 1986-01-24 1994-02-09 Akzo Nv Pharmaceutical preparation for obtaining a highly viscous hydrogel or suspension
US4971790A (en) * 1986-02-07 1990-11-20 Alza Corporation Dosage form for lessening irritation of mocusa
US4867969A (en) * 1986-02-07 1989-09-19 Alza Corporation Hydrogel formulation for administering non-steroidal drugs
JPS62223112A (ja) * 1986-03-25 1987-10-01 Rooto Seiyaku Kk 歯周病治療剤
DE3617158C2 (de) * 1986-05-22 1994-10-06 Lohmann Therapie Syst Lts Transdermales Arzneimittel
US5145682A (en) * 1986-05-30 1992-09-08 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit for postmenopausal syndrome treatment and process for administration
US4965253A (en) * 1987-10-14 1990-10-23 University Of Florida Viscoelastic material for ophthalmic surgery
US5656286A (en) 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5474783A (en) 1988-03-04 1995-12-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5133992A (en) * 1988-03-21 1992-07-28 Eastman Kodak Company Colloidally stabilized suspension process
US4931287A (en) * 1988-06-14 1990-06-05 University Of Utah Heterogeneous interpenetrating polymer networks for the controlled release of drugs
EP0347145A3 (en) * 1988-06-14 1990-10-24 University Of Utah Research Foundation Heterogeneous interpenetrating polymer networks for the controlled release of drugs
US5073381A (en) * 1988-08-15 1991-12-17 University Of Akron Amphiphilic networks
US5270358A (en) * 1989-12-28 1993-12-14 Minnesota Mining And Manufacturing Company Composite of a disperesed gel in an adhesive matrix
ES2062900B1 (es) * 1991-07-29 1995-07-01 Univ Madrid Nac Educacion Hidrogeles de polimero heterociclico, su procedimiento de obtencion y su utilizacion como pastillas insolubles reguladoras del ph.
JP3457308B2 (ja) * 1991-11-15 2003-10-14 ミネソタ マイニング アンド マニュファクチャリング カンパニー 二相複合導性感圧接着剤の施された生物医療電極
US5352448A (en) * 1992-07-20 1994-10-04 Purdue Research Foundatioin Oral administration of antigens
JP3624315B2 (ja) * 1992-07-29 2005-03-02 バクスター、インターナショナル、インコーポレイテッド 親水性表面を有する生物材料
DE4341156C2 (de) * 1993-12-02 1997-11-13 Wacker Chemie Gmbh Verwendung von in Wasser redispergierbaren Kunststoffdispersionspulvern als Arzneimittelträger
US5840338A (en) * 1994-07-18 1998-11-24 Roos; Eric J. Loading of biologically active solutes into polymer gels
US5603955A (en) * 1994-07-18 1997-02-18 University Of Cincinnati Enhanced loading of solutes into polymer gels
DE19622355A1 (de) * 1996-06-04 1997-12-11 Bayer Ag Formkörper die agrochemische Mittel freisetzen
DE19629468A1 (de) * 1996-07-11 1998-01-15 Schering Ag Transdermale therapeutische Systeme
US8003705B2 (en) 1996-09-23 2011-08-23 Incept Llc Biocompatible hydrogels made with small molecule precursors
US5814329A (en) * 1996-11-12 1998-09-29 Polytherapeutics, Inc. Hydrophilic polystyrene graft copolymer vehicle for intravaginal administration of pharmacologically active agents
DE19753298A1 (de) * 1997-12-01 1999-06-02 Basf Ag Verfahren zur Herstellung von festen Dosierungsformen
US20020188037A1 (en) * 1999-04-15 2002-12-12 Chudzik Stephen J. Method and system for providing bioactive agent release coating
EP1174157B1 (en) 1998-04-27 2005-06-29 Surmodics Inc. Bioactive agent release coating
US6632457B1 (en) * 1998-08-14 2003-10-14 Incept Llc Composite hydrogel drug delivery systems
EP1137373A4 (en) 1998-12-04 2004-05-19 Chandrashekhar P Pathak BIOCOMPATIBLE, CROSSLINKED POLYMERS
EP1491185B1 (en) 2002-03-14 2009-05-27 Medrx Co., Ltd. External medicine for wounds
US7097850B2 (en) 2002-06-18 2006-08-29 Surmodics, Inc. Bioactive agent release coating and controlled humidity method
US20040111144A1 (en) * 2002-12-06 2004-06-10 Lawin Laurie R. Barriers for polymeric coatings
WO2005003192A1 (en) * 2003-06-26 2005-01-13 Symyx Technologies, Inc. Synthesis of photoresist polymers
US20050152855A1 (en) * 2003-09-19 2005-07-14 Damian Hajduk Materials for enhanced delivery of hydrophilic active agents in personal care formulations
CA2563069A1 (en) 2004-04-06 2005-10-27 Surmodics, Inc. Coating compositions for bioactive agents
US8148560B2 (en) * 2005-09-23 2012-04-03 Teva Women's Health, Inc. Vaginal tablets comprising misoprostol and methods of making and using the same
US8636753B2 (en) * 2006-02-08 2014-01-28 Tyrx, Inc. Temporarily stiffened mesh prostheses
JP2010519183A (ja) * 2007-02-06 2010-06-03 インセプト エルエルシー 生理溶液の溶出のためのタンパク質の沈殿を用いる重合
CN201075472Y (zh) * 2007-05-28 2008-06-18 富士康(昆山)电脑接插件有限公司 电连接器
US9125807B2 (en) 2007-07-09 2015-09-08 Incept Llc Adhesive hydrogels for ophthalmic drug delivery
US8745133B2 (en) * 2008-03-28 2014-06-03 Yahoo! Inc. System and method for optimizing the storage of data
CN102395401B (zh) * 2009-02-12 2015-08-19 因赛普特有限责任公司 经由水凝胶塞的药物递送
US8961501B2 (en) 2010-09-17 2015-02-24 Incept, Llc Method for applying flowable hydrogels to a cornea
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4085168A (en) * 1971-02-22 1978-04-18 Cpc International Inc. Chemically joined, phase separated self-cured hydrophilic thermoplastic graft copolymers and their preparation
US4277582A (en) * 1978-03-03 1981-07-07 Ciba-Geigy Corporation Water-insoluble hydrophilic copolymers
SU806037A1 (ru) * 1978-04-06 1981-02-23 Всесоюзный Кардиологический Научныйцентр Amh Cccp Антиангинальное средство
SE448544B (sv) * 1979-12-05 1987-03-02 Kendall & Co Vattenabsorberande komposition och anvendning derav som berare for ett lekemedel
SU1243627A3 (ru) * 1979-12-05 1986-07-07 Дзе Кендалл Компани (Фирма) Гелеобразующа композици
US4259314A (en) * 1979-12-10 1981-03-31 Hans Lowey Method and composition for the preparation of controlled long-acting pharmaceuticals
US4423099A (en) * 1980-07-28 1983-12-27 Ciba-Geigy Corporation Membrane modified hydrogels
JPS5776046A (en) * 1980-10-27 1982-05-12 Kendall & Co Water absorbing composition

Also Published As

Publication number Publication date
NL8402833A (nl) 1985-04-01
CA1232201A (en) 1988-02-02
FR2551976A1 (fr) 1985-03-22
CH666415A5 (de) 1988-07-29
GB2147002B (en) 1987-11-11
GB2147002A (en) 1985-05-01
IT1178430B (it) 1987-09-09
PT79192A (en) 1984-10-01
AU577056B2 (en) 1988-09-15
IT8448836A1 (it) 1986-03-13
SE461502B (sv) 1990-02-26
ATA290884A (de) 1991-07-15
GB2177708A (en) 1987-01-28
ES8607357A1 (es) 1986-05-16
BR8404409A (pt) 1985-07-30
NO843650L (no) 1985-03-18
US4693887A (en) 1987-09-15
PT79192B (en) 1986-08-14
IT8448836A0 (it) 1984-09-13
GB8423416D0 (en) 1984-10-24
ES535923A0 (es) 1986-05-16
DE3432573A1 (de) 1985-04-18
DK410984A (da) 1985-03-16
BE900581A (fr) 1985-03-14
GB8620117D0 (en) 1986-10-01
AU3226884A (en) 1985-03-21
NZ209323A (en) 1987-04-30
FR2551976B1 (fr) 1988-06-10
DK410984D0 (da) 1984-08-28
SE8404568L (sv) 1985-03-16

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