SE8304456D0 - BASIC ACETANILIDES, PROCEDURES FOR THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THESE ACETANILIDES - Google Patents

BASIC ACETANILIDES, PROCEDURES FOR THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THESE ACETANILIDES

Info

Publication number
SE8304456D0
SE8304456D0 SE8304456A SE8304456A SE8304456D0 SE 8304456 D0 SE8304456 D0 SE 8304456D0 SE 8304456 A SE8304456 A SE 8304456A SE 8304456 A SE8304456 A SE 8304456A SE 8304456 D0 SE8304456 D0 SE 8304456D0
Authority
SE
Sweden
Prior art keywords
acetanilides
basic
optionally substituted
amino
procedures
Prior art date
Application number
SE8304456A
Other languages
Swedish (sv)
Other versions
SE8304456L (en
Inventor
E Rudinger
X Perlia
Original Assignee
Pharmaton Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmaton Sa filed Critical Pharmaton Sa
Publication of SE8304456D0 publication Critical patent/SE8304456D0/en
Publication of SE8304456L publication Critical patent/SE8304456L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A basic acetanilide of the general formula III <IMAGE> wherein R1 is hydrogen or optionally substituted alkyl, and R4 is halogen, optionally substituted alkoxy, an optionally substituted alkylthio, nitro, amino or optionally substituted alkylamino, propionyl or trihalogenmethyl, and R5 is a basic group, or a pharmacologically useful salt thereof. Preferably R is halogen or methyl, R4 is chlorine, bromine, trihalogen- methyl, ethoxy, nitro, amino, or propionyl and R5 is diethylamine, piperidino, pyrrolidino, cyclopropyl, amino or cyclopentylamino.
SE8304456A 1982-08-27 1983-08-17 BASIC ACETANILIDES, PROCEDURES FOR THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THESE ACETANILIDES SE8304456L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH5116/82A CH650768A5 (en) 1982-08-27 1982-08-27 BASIC ACETANILIDES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE ACETANILIDES.

Publications (2)

Publication Number Publication Date
SE8304456D0 true SE8304456D0 (en) 1983-08-17
SE8304456L SE8304456L (en) 1984-02-28

Family

ID=4288192

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8304456A SE8304456L (en) 1982-08-27 1983-08-17 BASIC ACETANILIDES, PROCEDURES FOR THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THESE ACETANILIDES

Country Status (8)

Country Link
JP (1) JPS59130250A (en)
CA (1) CA1214776A (en)
CH (1) CH650768A5 (en)
DE (1) DE3328186A1 (en)
FR (1) FR2532306B1 (en)
GB (1) GB2129424B (en)
IT (1) IT1168212B (en)
SE (1) SE8304456L (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7067666B2 (en) * 2003-06-27 2006-06-27 Research Triangle Institute 7-substituted camptothecin and camptothecin analogs and methods for producing the same
BRPI0404222A (en) * 2004-06-07 2006-02-07 Fundacao Oswaldo Cruz Lidocaine derivatives, pharmaceutical compositions containing them, use of the respective pharmaceutical compositions in the treatment, prevention or inhibition of diseases as well as the method of treating, preventing or inhibiting diseases with said pharmaceutical compositions

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE534406A (en) *
BE517755A (en) *
GB859355A (en) *
US2689853A (en) * 1954-09-21 Certain i
NL73080C (en) * 1950-03-03
GB726864A (en) * 1952-05-13 1955-03-23 Geistlich Soehne Ag New ª‰-dialkyl-aminobutyric acid anilide derivatives and a process for preparing thesame
DE1005075B (en) * 1952-08-18 1957-03-28 Hoechst Ag Process for the production of new locally anesthetically acting, basic substituted carboxamides
GB782971A (en) * 1952-08-18 1957-09-18 Hoechst Ag Basically substituted carboxylic acid amides and a process for making them
GB726050A (en) * 1953-10-16 1955-03-16 James Arthur Cooke A holder for chisels and plane irons whilst honing
GB759744A (en) * 1953-12-24 1956-10-24 Cilag Ltd Process for the production of mono- and di-substituted amino fatty acid-2-halogeno-6-methyl-anilides
GB809286A (en) * 1954-07-05 1959-02-18 Hoechst Ag Basically substituted butyric acid anilides and process for their manufacture
CH329572A (en) * 1954-07-29 1958-04-30 Cilag Ag Process for the preparation of basic amides
CH306793A (en) * 1955-04-30 1955-04-30 Cilag Ag Process for making a new salt.
US2948736A (en) * 1957-08-05 1960-08-09 Cilag Chemie New anilides and process for their production
NL262748A (en) * 1960-03-23
NL6704169A (en) * 1966-04-06 1967-10-09
GB1187118A (en) * 1967-07-06 1970-04-08 Shell Int Research Electrodeposition of Synthetic Resin Coatings
GB1307250A (en) * 1970-06-16 1973-02-14 May & Baker Ltd Benzene derivatives
SE410732B (en) * 1971-12-13 1979-10-29 Sumitomo Chemical Co ANALOGICAL PROCEDURE FOR THE PREPARATION OF ANILIDE DERIVATIVES WITH THERAPEUTIC EFFECT
CS195321B2 (en) * 1975-12-23 1980-01-31 Ciba Geigy Ag Plant growth suppressing agents
GB1514151A (en) * 1977-01-24 1978-06-14 Gallardo Antonio Sa Piperidine derivatives

Also Published As

Publication number Publication date
SE8304456L (en) 1984-02-28
GB2129424A (en) 1984-05-16
IT1168212B (en) 1987-05-20
JPS59130250A (en) 1984-07-26
DE3328186A1 (en) 1984-03-01
FR2532306B1 (en) 1989-03-10
GB2129424B (en) 1986-07-09
FR2532306A1 (en) 1984-03-02
IT8348886A0 (en) 1983-08-26
CA1214776A (en) 1986-12-02
CH650768A5 (en) 1985-08-15
GB8321953D0 (en) 1983-09-14

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Effective date: 19880801