SE8304315L - MOLDING ALKALOIDS, THEIR PREPARATION AND USE - Google Patents

MOLDING ALKALOIDS, THEIR PREPARATION AND USE

Info

Publication number
SE8304315L
SE8304315L SE8304315A SE8304315A SE8304315L SE 8304315 L SE8304315 L SE 8304315L SE 8304315 A SE8304315 A SE 8304315A SE 8304315 A SE8304315 A SE 8304315A SE 8304315 L SE8304315 L SE 8304315L
Authority
SE
Sweden
Prior art keywords
alkyl
alkaloids
molding
preparation
agents
Prior art date
Application number
SE8304315A
Other languages
Swedish (sv)
Other versions
SE8304315D0 (en
Inventor
P Gull
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE8304315D0 publication Critical patent/SE8304315D0/en
Publication of SE8304315L publication Critical patent/SE8304315L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

2-methyl-lysergyl ethers and thioethers are useful neuroleptics, anti-migraine agents, cerebral insufficiency agents, agents for senile dementia and anti-depressants. Preferably compounds of formula <IMAGE> where X is O or S, R1 is H, C1-4 alkyl or phenyl, R2 is C1-3 alkyl and R3 is phenyl or pyridyl, which may be substituted, or alkyl are used.
SE8304315A 1982-08-09 1983-08-08 MOLDING ALKALOIDS, THEIR PREPARATION AND USE SE8304315L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH4772/82A CH649998A5 (en) 1982-08-09 1982-08-09 ERGOL DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND HEALING AGENTS, CONTAINING THESE ERGOL DERIVATIVES AS AN ACTIVE SUBSTANCE.

Publications (2)

Publication Number Publication Date
SE8304315D0 SE8304315D0 (en) 1983-08-08
SE8304315L true SE8304315L (en) 1984-02-10

Family

ID=4282273

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8304315A SE8304315L (en) 1982-08-09 1983-08-08 MOLDING ALKALOIDS, THEIR PREPARATION AND USE

Country Status (23)

Country Link
JP (1) JPS5948480A (en)
AT (1) AT383125B (en)
AU (1) AU563736B2 (en)
BE (1) BE897473A (en)
CA (1) CA1215972A (en)
CH (1) CH649998A5 (en)
DE (1) DE3327705A1 (en)
DK (1) DK361983A (en)
ES (1) ES524815A0 (en)
FI (1) FI73679C (en)
FR (1) FR2531433B1 (en)
GB (1) GB2125041B (en)
GR (1) GR78923B (en)
HU (1) HU187600B (en)
IL (1) IL69450A (en)
IT (1) IT1168961B (en)
MY (1) MY8700166A (en)
NL (1) NL8302776A (en)
NZ (1) NZ205181A (en)
PH (1) PH20385A (en)
PT (1) PT77168B (en)
SE (1) SE8304315L (en)
ZA (1) ZA835850B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675322A (en) * 1984-12-10 1987-06-23 Eli Lilly And Company 1-Substituted-6-n-propyl-8β-methylthio-methylergolines
HU193782B (en) * 1985-06-21 1987-11-30 Richter Gedeon Vegyeszet Process for producing 2-halogeno-nicergoline derivatives and acid additional salts thereof
FR2589734B1 (en) * 1985-11-13 1988-09-02 Roussel Uclaf USE OF ERGOLIN DERIVATIVES FOR OBTAINING A GERIATRIC MEDICINE
US4798834A (en) * 1987-08-31 1989-01-17 Eli Lilly And Company Optionally substituted (3β-9,10-didehydro-2,3-dihydro ergoline as serotonergic function enhancement
DE3913756A1 (en) * 1989-04-21 1990-10-25 Schering Ag 8 (BETA) SUBSTITUTED ERGOLINE, METHOD FOR THE PRODUCTION AND USE THEREOF
DE10212564B4 (en) * 2002-03-12 2007-04-19 Neurobiotec Gmbh 1-Allyl ergot alkaloid derivatives and their use for the prophylaxis and treatment of migraine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE41533B1 (en) * 1974-03-14 1980-01-30 Sandoz Ltd Thiomethyl ergolene derivatives
US3901894A (en) * 1974-06-06 1975-08-26 Lilly Co Eli 8-thiomethylergolines
US3959288A (en) * 1974-12-13 1976-05-25 Eli Lilly And Company 8-Oxymethylergolines and process therefor
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4382940A (en) * 1979-12-06 1983-05-10 Farmitalia Carlo Erba S.P.A. Ercoline derivatives and therapeutic compositions having CNS affecting activity

Also Published As

Publication number Publication date
ZA835850B (en) 1985-03-27
CA1215972A (en) 1986-12-30
JPS5948480A (en) 1984-03-19
AT383125B (en) 1987-05-25
FI832789A0 (en) 1983-08-02
GB2125041A (en) 1984-02-29
FR2531433B1 (en) 1985-10-18
IL69450A (en) 1986-10-31
HU187600B (en) 1986-01-28
SE8304315D0 (en) 1983-08-08
AU1767283A (en) 1984-02-16
PH20385A (en) 1986-12-08
ES8502992A1 (en) 1985-02-01
IT8322490A0 (en) 1983-08-09
DE3327705A1 (en) 1984-02-09
PT77168B (en) 1986-03-27
CH649998A5 (en) 1985-06-28
BE897473A (en) 1984-02-06
GB8321222D0 (en) 1983-09-07
MY8700166A (en) 1987-12-31
DK361983A (en) 1984-02-10
IL69450A0 (en) 1983-11-30
FR2531433A1 (en) 1984-02-10
ATA286383A (en) 1986-10-15
ES524815A0 (en) 1985-02-01
AU563736B2 (en) 1987-07-23
FI73679C (en) 1987-11-09
FI73679B (en) 1987-07-31
GB2125041B (en) 1986-04-23
NZ205181A (en) 1986-07-11
DK361983D0 (en) 1983-08-08
FI832789A (en) 1984-02-10
GR78923B (en) 1984-10-02
NL8302776A (en) 1984-03-01
IT1168961B (en) 1987-05-20
PT77168A (en) 1983-09-01

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