SE8303626D0 - A recombinant plasmid a transformant microorganism, a polydoxyrebonucleotide segment, a process for producing a biologically active protein, and the protein thus produced - Google Patents

A recombinant plasmid a transformant microorganism, a polydoxyrebonucleotide segment, a process for producing a biologically active protein, and the protein thus produced

Info

Publication number
SE8303626D0
SE8303626D0 SE8303626A SE8303626A SE8303626D0 SE 8303626 D0 SE8303626 D0 SE 8303626D0 SE 8303626 A SE8303626 A SE 8303626A SE 8303626 A SE8303626 A SE 8303626A SE 8303626 D0 SE8303626 D0 SE 8303626D0
Authority
SE
Sweden
Prior art keywords
protein
plasmid
igf
growth factor
human insulin
Prior art date
Application number
SE8303626A
Other languages
English (en)
Swedish (sv)
Inventor
A Elmblad
G Palm
S Josephson
L-O Heden
E Holmgren
Original Assignee
Kabigen Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabigen Ab filed Critical Kabigen Ab
Priority to SE8303626A priority Critical patent/SE8303626D0/xx
Publication of SE8303626D0 publication Critical patent/SE8303626D0/xx
Priority to IT21436/84A priority patent/IT1175508B/it
Priority to EP84850197A priority patent/EP0130166A1/en
Priority to JP59129038A priority patent/JPS6019493A/ja
Priority to GB08416007A priority patent/GB2142033A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
SE8303626A 1983-06-23 1983-06-23 A recombinant plasmid a transformant microorganism, a polydoxyrebonucleotide segment, a process for producing a biologically active protein, and the protein thus produced SE8303626D0 (sv)

Priority Applications (5)

Application Number Priority Date Filing Date Title
SE8303626A SE8303626D0 (sv) 1983-06-23 1983-06-23 A recombinant plasmid a transformant microorganism, a polydoxyrebonucleotide segment, a process for producing a biologically active protein, and the protein thus produced
IT21436/84A IT1175508B (it) 1983-06-23 1984-06-15 Un plasmide ricombinante, un microorganismo trasformante un segmento di polideossiribonucleotide, un procedimento per produrre una proteina biologicamente attiva e la proteina cosi' prodotta
EP84850197A EP0130166A1 (en) 1983-06-23 1984-06-20 A recombinant plasmid, a transformant microorganism, a polydeoxy-ribonucleotide segment, a process for producing a biologically active protein, and the protein thus produced
JP59129038A JPS6019493A (ja) 1983-06-23 1984-06-22 組換え体プラスミド，形質転換体微生物，ポリデオキシリボヌクレオチド断片，生物学的に活性な蛋白質およびその製法
GB08416007A GB2142033A (en) 1983-06-23 1984-06-22 Human insulin-like growth factor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8303626A SE8303626D0 (sv) 1983-06-23 1983-06-23 A recombinant plasmid a transformant microorganism, a polydoxyrebonucleotide segment, a process for producing a biologically active protein, and the protein thus produced

Publications (1)

Publication Number Publication Date
SE8303626D0 true SE8303626D0 (sv) 1983-06-23

Family

ID=20351747

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8303626A SE8303626D0 (sv) 1983-06-23 1983-06-23 A recombinant plasmid a transformant microorganism, a polydoxyrebonucleotide segment, a process for producing a biologically active protein, and the protein thus produced

Country Status (5)

Country Link
EP (1) EP0130166A1 (xx)
JP (1) JPS6019493A (xx)
GB (1) GB2142033A (xx)
IT (1) IT1175508B (xx)
SE (1) SE8303626D0 (xx)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL71991A (en) 1983-06-06 1994-05-30 Genentech Inc Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes
WO1985000831A1 (en) * 1983-08-10 1985-02-28 Amgen Microbial expression of insulin-like growth factor
DK108685A (da) * 1984-03-19 1985-09-20 Fujisawa Pharmaceutical Co Vaekstfaktor i
GB8522977D0 (en) * 1985-09-17 1985-10-23 Fujisawa Pharmaceutical Co Production of insulin-like growth factor 1
US4738921A (en) * 1984-09-27 1988-04-19 Eli Lilly And Company Derivative of the tryptophan operon for expression of fused gene products
GB8507833D0 (en) * 1985-03-26 1985-05-01 Biogen Nv Production of human somatomedin c
EP0219814B1 (en) * 1985-10-21 1991-09-11 Fujisawa Pharmaceutical Co., Ltd. Process for production of isulin-like growth factor i and plasmid for production thereof
JPH0817708B2 (ja) * 1986-10-09 1996-02-28 藤沢薬品工業株式会社 Ｍｅｔ−インスリン様成長因子Ｉの発現ベクター
JPH03505966A (ja) * 1988-07-14 1991-12-26 ベイラー カレッジ オブ メディシン 生物高分子の固相組立及び再構築方法
EP0385410B1 (en) * 1989-02-28 1996-10-02 Canon Kabushiki Kaisha Partially double-stranded oligonucleotide and method for forming oligonucleotide
JP2682738B2 (ja) * 1989-06-09 1997-11-26 グロペップ プロプライエタリー リミテッド 成長ホルモン融合蛋白質
KR920003787B1 (ko) * 1990-03-05 1992-05-14 한국과학기술 연구원 신규 플라스미드 제조 및 그를 함유한 균주를 배양하여 아이 지 에프-1(igf-1)을 생산하는 방법
US5288931A (en) * 1991-12-06 1994-02-22 Genentech, Inc. Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation
WO1993019084A1 (en) * 1992-03-24 1993-09-30 Synergen, Inc. Refolding and purification of insulin-like growth factor i
US5663304A (en) * 1993-08-20 1997-09-02 Genentech, Inc. Refolding of misfolded insulin-like growth factor-I
DE59915204D1 (de) 1998-08-28 2010-10-28 Febit Holding Gmbh Verfahren zur herstellung von biochemischen reaktionsträgern
WO2000049142A1 (de) * 1999-02-19 2000-08-24 Febit Ferrarius Biotechnology Gmbh Verfahren zur herstellung von polymeren
CN107007842A (zh) 2005-05-02 2017-08-04 建新公司 神经代谢疾病的基因治疗
MX2007013734A (es) 2005-05-02 2008-03-14 Genzyme Corp Terapia genica para trastornos de la medula espinal.
AR059089A1 (es) 2006-01-20 2008-03-12 Genzyme Corp Administracion intraventricular de una enzima para enfermedades de almacenamiento lisosomal
AR059088A1 (es) * 2006-01-20 2008-03-12 Genzyme Corp Administracion intraventricular de una proteina para esclerosis lateral amiotrofica
EP1988823B1 (en) 2006-02-09 2018-08-15 Genzyme Corporation Slow intraventricular delivery
PL2029742T3 (pl) 2006-06-07 2017-08-31 Genzyme Corporation Terapia genowa w stwardnieniu zanikowym bocznym i innych zaburzeniach rdzenia kręgowego
DK2497500T3 (da) 2006-10-03 2017-01-02 Genzyme Corp Genterapi mod spinal muskelatrofi

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201918A (en) * 1981-09-18 1987-04-30 Genentech Inc N-terminal methionyl analogues of bovine growth hormone

Also Published As

Publication number Publication date
EP0130166A1 (en) 1985-01-02
IT8421436A1 (it) 1985-12-15
IT8421436A0 (it) 1984-06-15
GB2142033A (en) 1985-01-09
GB8416007D0 (en) 1984-07-25
IT1175508B (it) 1987-07-01
JPS6019493A (ja) 1985-01-31

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