SE8303539D0 - POLYENVERBINDUNGEN - Google Patents

POLYENVERBINDUNGEN

Info

Publication number
SE8303539D0
SE8303539D0 SE8303539A SE8303539A SE8303539D0 SE 8303539 D0 SE8303539 D0 SE 8303539D0 SE 8303539 A SE8303539 A SE 8303539A SE 8303539 A SE8303539 A SE 8303539A SE 8303539 D0 SE8303539 D0 SE 8303539D0
Authority
SE
Sweden
Prior art keywords
alkyl
formula
amino
alkoxy
halogen
Prior art date
Application number
SE8303539A
Other languages
Swedish (sv)
Other versions
SE454984B (en
SE8303539L (en
Inventor
E P Krebs
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SE8303539D0 publication Critical patent/SE8303539D0/en
Publication of SE8303539L publication Critical patent/SE8303539L/en
Publication of SE454984B publication Critical patent/SE454984B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/74—Unsaturated compounds containing —CHO groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
    • C07C57/50—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Compounds of the formula <IMAGE> wherein R<1> is a group of the formula <IMAGE> R<2> is hydroxy, lower-alkoxy, amino, mono-(lower-alkyl)amino or di-(lower-alkyl)- amino, R<3> is lower-alkyl or halogen, R<4> is lower-alkyl, R<5> is lower-alkoxy, R<6> is hydrogen or lower-alkyl and R<7> is lower-alkyl or halogen, and pharmaceutically acceptable salts of the carboxylic acids of formula I can be used for the treatment of neo-plasms and dermatoses. The compounds of formula I can be obtained by forming the side-chain from corresponding cyclic and aliphatic for components by means of a Wittig or Horner reaction.
SE8303539A 1982-06-24 1983-06-20 POLYENIC SOCIETIES, PROCEDURES FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE SE454984B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH3889/82A CH651007A5 (en) 1982-06-24 1982-06-24 POLYEN CONNECTIONS.

Publications (3)

Publication Number Publication Date
SE8303539D0 true SE8303539D0 (en) 1983-06-20
SE8303539L SE8303539L (en) 1983-12-25
SE454984B SE454984B (en) 1988-06-13

Family

ID=4265678

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8303539A SE454984B (en) 1982-06-24 1983-06-20 POLYENIC SOCIETIES, PROCEDURES FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE

Country Status (19)

Country Link
JP (1) JPS5910547A (en)
AT (1) AT392780B (en)
AU (1) AU560027B2 (en)
BE (1) BE897118A (en)
CA (1) CA1276032C (en)
CH (1) CH651007A5 (en)
DE (1) DE3321662A1 (en)
DK (1) DK159392C (en)
FR (1) FR2529201B1 (en)
GB (2) GB2122200B (en)
IE (1) IE55285B1 (en)
IL (1) IL69028A0 (en)
IT (1) IT1212753B (en)
LU (1) LU84870A1 (en)
NL (1) NL8302136A (en)
NZ (1) NZ204628A (en)
PH (1) PH20070A (en)
SE (1) SE454984B (en)
ZA (1) ZA834473B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1203634B (en) * 1984-08-13 1989-02-15 Oreal 1-SUBSTITUTED DERIVATIVES OF 4-METHOXY-2,3,6-TRIMETHYLBENZENE THEIR PREPARATION PROCESS AND MEDICAMENTOUS AND COSMETIC COMPOSITIONS CONTAINING THEM
FR2621912B1 (en) * 1987-10-16 1990-03-02 Oreal NOVEL NORBORNANE DERIVATIVES, THEIR PREPARATION PROCESS AND COSMETIC AND MEDICINAL COMPOSITIONS CONTAINING THEM
DE4033568A1 (en) * 1990-10-22 1992-04-23 Henkel Kgaa BICYCLIC COMPOUNDS WITH ANTISEBORRHOIC EFFECT
CA2196197C (en) * 1994-08-10 2007-04-17 Michael Klaus Retinoic acid x-receptor ligands

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1070173B (en) * 1959-12-03 Badische Anilin- S. Soda-Fabrik Aktiengesellschaft, Ludwigshafen / Rhein Process for the preparation of 13- [2 ', 6', 6'-trimethylcyclohexen- (l ') - yl- (l')] - 3,7, ll-trimethyltridecahexaene - (2,4,6,8,10, 12) - säureil) or their esters
DE923252C (en) * 1944-09-23 1955-02-07 Schering Ag Process for the preparation of a polyenecarboxylic acid of the formula CHO
AT207831B (en) * 1957-11-27 1960-02-25 Hoffmann La Roche Process for the preparation of polyenecarboxylic acid esters and their saponification products
AT222103B (en) * 1958-08-07 1962-07-10 Bayer Ag Process for the preparation of 2-trans-β-ionylideneacetic acid
CH529742A (en) * 1970-02-02 1972-10-31 Hoffmann La Roche Process for the production of vitamin A acid amides
AT340903B (en) * 1974-03-29 1978-01-10 Hoffmann La Roche PROCESS FOR PRODUCING NEW POLYENE COMPOUNDS
DE2456959A1 (en) * 1974-12-03 1976-06-16 Basf Ag 4- (E) - AND 4- (Z) -7-METHYL-9- (2,6,6TRIMETHYL-1-CYCLOHEXEN-1-YL) -NONA-2,4,6,8TETRAEN CARBONIC ACID, ITS DERIVATIVES AND CONTAINING THEM PREPARATIONS
CH624373A5 (en) * 1975-11-14 1981-07-31 Hoffmann La Roche Process for the preparation of polyene compounds
CA1111441A (en) * 1976-12-20 1981-10-27 Werner Bollag Polyene compounds
LU77254A1 (en) * 1977-05-04 1979-01-18
US4169103A (en) * 1978-04-12 1979-09-25 Hoffmann-La Roche Inc. Nonatetraenoic acid derivatives
DE2843884A1 (en) * 1978-10-07 1980-04-24 Basf Ag MEDIUM CONTAINING 2- (RETINYLIDES) - MALONIC ACID DERIVATIVES

Also Published As

Publication number Publication date
FR2529201A1 (en) 1983-12-30
DK159392B (en) 1990-10-08
IE831471L (en) 1983-12-24
DE3321662A1 (en) 1983-12-29
CA1276032C (en) 1990-11-06
NZ204628A (en) 1985-07-31
AT392780B (en) 1991-06-10
GB8317129D0 (en) 1983-07-27
BE897118A (en) 1983-12-23
GB2156351A (en) 1985-10-09
GB8510717D0 (en) 1985-06-05
JPH0441134B2 (en) 1992-07-07
DK159392C (en) 1991-03-04
AU1620183A (en) 1984-01-05
DE3321662C2 (en) 1992-11-26
IT8321721A0 (en) 1983-06-21
IL69028A0 (en) 1983-10-31
NL8302136A (en) 1984-01-16
GB2156351B (en) 1986-05-14
SE454984B (en) 1988-06-13
GB2122200A (en) 1984-01-11
PH20070A (en) 1986-09-18
IE55285B1 (en) 1990-08-01
CH651007A5 (en) 1985-08-30
ZA834473B (en) 1984-03-28
FR2529201B1 (en) 1988-08-19
DK287083A (en) 1983-12-25
DK287083D0 (en) 1983-06-21
IT1212753B (en) 1989-11-30
LU84870A1 (en) 1985-03-29
AU560027B2 (en) 1987-03-26
ATA230583A (en) 1990-11-15
SE8303539L (en) 1983-12-25
GB2122200B (en) 1986-05-08
JPS5910547A (en) 1984-01-20

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