SE8300422D0 - EMULSION FOR USE AS PERFUSION MATERIAL - Google Patents
EMULSION FOR USE AS PERFUSION MATERIALInfo
- Publication number
- SE8300422D0 SE8300422D0 SE8300422A SE8300422A SE8300422D0 SE 8300422 D0 SE8300422 D0 SE 8300422D0 SE 8300422 A SE8300422 A SE 8300422A SE 8300422 A SE8300422 A SE 8300422A SE 8300422 D0 SE8300422 D0 SE 8300422D0
- Authority
- SE
- Sweden
- Prior art keywords
- emulsions
- transplanted
- organs
- perfluorination
- products
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/02—Halogenated hydrocarbons
- A61K31/025—Halogenated hydrocarbons carbocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
An emulsion for flushing organs to be transplanted is described, which contains perfluorinated hydrocarbons, dispersed in water, and additionally a non-toxic emulsifier. It must contain a total of more than 40% by volume of water. The perfluorinated materials are the perfluorination products of either (1) polycyclic hydrocarbons having at least two bridge head carbon atoms linked to each other via a bridge containing at least one carbon atom and which are not adamantane, or (2) methyladamantane, ethyladamantane, ethylmethyladamantane, ethyldimethyladamantane or triethyladamantane. These perfluorination products have an excellent dissolving capacity for oxygen and carbon dioxide and they form highly stable emulsions with good resistance to the high shearing forces which are applied to the emulsions when they flow through apparatuses which load the emulsions with the necessary oxygen, which they transport to the organs to be transplanted. The emulsions permit organs which are to be transplanted to be stored for a long time, and when, on the other hand, part of the emulsions reaches the human body as the organs through which the emulsions flow are transplanted, they are not toxic there and are excreted again after some time by way of respiration and via the skin.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53079174A | 1974-12-09 | 1974-12-09 | |
US57976675A | 1975-05-22 | 1975-05-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8300422L SE8300422L (en) | 1983-01-27 |
SE8300422D0 true SE8300422D0 (en) | 1983-01-27 |
Family
ID=27063372
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7513814A SE7513814L (en) | 1974-12-09 | 1975-12-08 | PERFLUORATED POLYCYCLIC ASSOCIATIONS USE AS BLOOD SUPPLYING AND PERFUSION MEDIA |
SE8300422A SE8300422D0 (en) | 1974-12-09 | 1983-01-27 | EMULSION FOR USE AS PERFUSION MATERIAL |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7513814A SE7513814L (en) | 1974-12-09 | 1975-12-08 | PERFLUORATED POLYCYCLIC ASSOCIATIONS USE AS BLOOD SUPPLYING AND PERFUSION MEDIA |
Country Status (12)
Country | Link |
---|---|
JP (1) | JPS5753762B2 (en) |
CA (1) | CA1058081A (en) |
CH (1) | CH629938A5 (en) |
DE (1) | DE2555408A1 (en) |
DK (1) | DK154605C (en) |
FI (1) | FI54560C (en) |
FR (1) | FR2313024A1 (en) |
GB (1) | GB1531418A (en) |
IT (1) | IT1050731B (en) |
NL (1) | NL184995C (en) |
NO (1) | NO754103L (en) |
SE (2) | SE7513814L (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2515198A1 (en) * | 1981-10-22 | 1983-04-29 | Centre Nat Rech Scient | AQUEOUS MICROEMULSIONS OF FLUOROCARBONS INDUFINIMENTALLY STABLE AT A DATA TEMPERATURE, PROCESS FOR OBTAINING AND APPLICATION AS OXYGEN TRANSPORTERS |
US4569784A (en) * | 1980-11-17 | 1986-02-11 | Adamantech, Inc. | Preparation of a gel having gas transporting capability |
GB8504916D0 (en) * | 1985-02-26 | 1985-03-27 | Isc Chemicals Ltd | Emulsions of perfluorocarbons in aqueous media |
DE4100059C2 (en) * | 1991-01-03 | 1994-08-25 | Adatomed Pharma & Med | Treatment liquid for reapplication (detached) of detached retina to the choroid of the eye |
EP2373289A4 (en) * | 2008-12-08 | 2014-07-02 | Univ Utah Res Found | Stable perfluorocarbon emulsion for use as an artificial oxygen carrier |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH604490A5 (en) * | 1970-09-05 | 1978-09-15 | Green Cross Corp | |
GB1343870A (en) * | 1971-05-19 | 1974-01-16 | Green Cross Corp | Emulsions and the preparation thereof |
US3911138B1 (en) * | 1973-02-26 | 1996-10-29 | Childrens Hosp Medical Center | Artificial blood and method for supporting oxygen transport in animals |
JPS5331209B2 (en) * | 1973-10-05 | 1978-09-01 |
-
1975
- 1975-11-28 IT IT29807/75A patent/IT1050731B/en active
- 1975-12-03 CH CH1572675A patent/CH629938A5/en not_active IP Right Cessation
- 1975-12-04 JP JP50143428A patent/JPS5753762B2/ja not_active Expired
- 1975-12-04 NO NO754103A patent/NO754103L/no unknown
- 1975-12-05 NL NLAANVRAGE7514202,A patent/NL184995C/en not_active IP Right Cessation
- 1975-12-05 CA CA241,138A patent/CA1058081A/en not_active Expired
- 1975-12-08 SE SE7513814A patent/SE7513814L/en unknown
- 1975-12-08 DK DK554675A patent/DK154605C/en not_active IP Right Cessation
- 1975-12-08 FI FI753442A patent/FI54560C/en not_active IP Right Cessation
- 1975-12-09 FR FR7537587A patent/FR2313024A1/en active Granted
- 1975-12-09 GB GB50472/75A patent/GB1531418A/en not_active Expired
- 1975-12-09 DE DE19752555408 patent/DE2555408A1/en active Granted
-
1983
- 1983-01-27 SE SE8300422A patent/SE8300422D0/en unknown
Also Published As
Publication number | Publication date |
---|---|
DK154605C (en) | 1989-06-05 |
SE7513814L (en) | 1976-06-10 |
CA1058081A (en) | 1979-07-10 |
JPS5753762B2 (en) | 1982-11-15 |
NL184995B (en) | 1989-08-01 |
FI54560B (en) | 1978-09-29 |
JPS5198318A (en) | 1976-08-30 |
IT1050731B (en) | 1981-03-20 |
NL184995C (en) | 1990-01-02 |
DE2555408C2 (en) | 1988-06-23 |
CH629938A5 (en) | 1982-05-28 |
DK554675A (en) | 1976-06-10 |
DE2555408A1 (en) | 1976-06-10 |
DK154605B (en) | 1988-12-05 |
FR2313024A1 (en) | 1976-12-31 |
SE8300422L (en) | 1983-01-27 |
NL7514202A (en) | 1976-06-11 |
FI54560C (en) | 1979-01-10 |
NO754103L (en) | 1976-06-10 |
FI753442A (en) | 1976-06-10 |
GB1531418A (en) | 1978-11-08 |
FR2313024B1 (en) | 1980-05-23 |
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