SE8203855D0 - Novel derivatives of guanine i - Google Patents

Novel derivatives of guanine i

Info

Publication number
SE8203855D0
SE8203855D0 SE8203855A SE8203855A SE8203855D0 SE 8203855 D0 SE8203855 D0 SE 8203855D0 SE 8203855 A SE8203855 A SE 8203855A SE 8203855 A SE8203855 A SE 8203855A SE 8203855 D0 SE8203855 D0 SE 8203855D0
Authority
SE
Sweden
Prior art keywords
methoxy
fluoro
hydrogen
methylthio
compounds
Prior art date
Application number
SE8203855A
Other languages
English (en)
Swedish (sv)
Inventor
K I Eklind
K B Gotthammar
C-E Hagberg
Z M I Kovacs K N-G Johansson
J-O Noren
G B Stening
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Priority to SE8203855A priority Critical patent/SE8203855D0/xx
Publication of SE8203855D0 publication Critical patent/SE8203855D0/xx
Priority to EP83901965A priority patent/EP0112353A1/en
Priority to AU17060/83A priority patent/AU1706083A/en
Priority to DE8383850170T priority patent/DE3362283D1/de
Priority to PCT/SE1983/000254 priority patent/WO1984000167A1/en
Priority to AT83850170T priority patent/ATE18225T1/de
Priority to ES523425A priority patent/ES523425A0/es
Priority to GR71722A priority patent/GR78621B/el
Priority to PT76902A priority patent/PT76902B/pt
Priority to PH29089A priority patent/PH19399A/en
Priority to GB08316743A priority patent/GB2122198B/en
Priority to NZ204640A priority patent/NZ204640A/en
Priority to JP58502135A priority patent/JPS59501112A/ja
Priority to EP83850170A priority patent/EP0103551B1/en
Priority to IS2822A priority patent/IS2822A7/is
Priority to DD83252201A priority patent/DD210274A5/de
Priority to ZA834532A priority patent/ZA834532B/xx
Priority to KR1019830002777A priority patent/KR840005141A/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04—Saturated ethers
    • C07C43/13—Saturated ethers containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/16—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE8203855A 1982-06-21 1982-06-21 Novel derivatives of guanine i SE8203855D0 (sv)

Priority Applications (18)

Application Number Priority Date Filing Date Title
SE8203855A SE8203855D0 (sv) 1982-06-21 1982-06-21 Novel derivatives of guanine i
EP83850170A EP0103551B1 (en) 1982-06-21 1983-06-20 Novel derivatives of guanine
PT76902A PT76902B (en) 1982-06-21 1983-06-20 Process for preparing novel derivatives of guanine and of pharmaceutical compositions containing the same
GB08316743A GB2122198B (en) 1982-06-21 1983-06-20 Antiviral guanine derivatives
DE8383850170T DE3362283D1 (en) 1982-06-21 1983-06-20 Novel derivatives of guanine
PCT/SE1983/000254 WO1984000167A1 (en) 1982-06-21 1983-06-20 Novel derivatives of guanine i
AT83850170T ATE18225T1 (de) 1982-06-21 1983-06-20 Guanin-derivate.
ES523425A ES523425A0 (es) 1982-06-21 1983-06-20 Un metodo para preparar nuevos derivados de guanina
GR71722A GR78621B (xx) 1982-06-21 1983-06-20
EP83901965A EP0112353A1 (en) 1982-06-21 1983-06-20 Novel derivatives of guanine i
PH29089A PH19399A (en) 1982-06-21 1983-06-20 Novel derivatives of guanine
AU17060/83A AU1706083A (en) 1982-06-21 1983-06-20 Novel derivatives of guanine i
NZ204640A NZ204640A (en) 1982-06-21 1983-06-20 Guanine derivatives,methods for their preparation and pharmaceutical compositions which contain them
JP58502135A JPS59501112A (ja) 1982-06-21 1983-06-20 グアニンの新規誘導体１
KR1019830002777A KR840005141A (ko) 1982-06-21 1983-06-21 구아닌 유도체 및 그 제조방법
IS2822A IS2822A7 (is) 1982-06-21 1983-06-21 Ný aukaefni úr Guanine I
DD83252201A DD210274A5 (de) 1982-06-21 1983-06-21 Verfahren zur herstellung von guaninderivaten
ZA834532A ZA834532B (en) 1982-06-21 1983-06-21 Novel derivatives of guanine i

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8203855A SE8203855D0 (sv) 1982-06-21 1982-06-21 Novel derivatives of guanine i

Publications (1)

Publication Number Publication Date
SE8203855D0 true SE8203855D0 (sv) 1982-06-21

Family

ID=20347137

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8203855A SE8203855D0 (sv) 1982-06-21 1982-06-21 Novel derivatives of guanine i

Country Status (17)

Country Link
EP (2) EP0112353A1 (xx)
JP (1) JPS59501112A (xx)
KR (1) KR840005141A (xx)
AT (1) ATE18225T1 (xx)
AU (1) AU1706083A (xx)
DD (1) DD210274A5 (xx)
DE (1) DE3362283D1 (xx)
ES (1) ES523425A0 (xx)
GB (1) GB2122198B (xx)
GR (1) GR78621B (xx)
IS (1) IS2822A7 (xx)
NZ (1) NZ204640A (xx)
PH (1) PH19399A (xx)
PT (1) PT76902B (xx)
SE (1) SE8203855D0 (xx)
WO (1) WO1984000167A1 (xx)
ZA (1) ZA834532B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5684153A (en) 1984-08-16 1997-11-04 Beecham Group Plc Process for the preparation of purine derivatives
IL73682A (en) * 1983-12-20 1991-08-16 Medivir Ab Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation
EP0152316B1 (en) * 1984-01-26 1989-07-26 Merck & Co. Inc. Substituted butyl guanines and their utilization in antiviral compositions
US4617304A (en) * 1984-04-10 1986-10-14 Merck & Co., Inc. Purine derivatives
GR862141B (en) * 1985-08-16 1986-12-23 Glaxo Group Ltd Guanine derivatives
DE3627024A1 (de) 1985-09-24 1987-04-02 Hoechst Ag In 6- und 9-stellung substituierte 2-aminopurine, ihre verwendung, diese purine enthaltende arzneimittel und verfahren zur herstellung der purine
DE3604899A1 (de) * 1986-02-17 1987-08-20 Hoechst Ag Chirale umsetzungsprodukte aus mesogenen molekuelbausteinen und bifunktionell reaktionsfaehigen butantetraolderivaten und ihre verwendung als dotierstoff in fluessigkristall-phasen
EP0290630A4 (de) * 1986-11-25 1990-02-26 Inst Organicheskogo Sinteza Ak 9-substituierte guanine.
US4973318A (en) * 1988-02-10 1990-11-27 D.C.P. Af 1988 A/S Disposable syringe
US5216141A (en) * 1988-06-06 1993-06-01 Benner Steven A Oligonucleotide analogs containing sulfur linkages
US4966895A (en) * 1989-02-02 1990-10-30 Merck & Co. Inc. Cyclic monophosphates of purine and pyrimidine acyclonucleosides as anti-retroviral agents
ATE417925T1 (de) 1999-07-20 2009-01-15 Morphosys Ag Verfahren zur präsentation von (poly)peptiden/proteinen auf bakteriophagenpartikeln via disulfidbindungen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
US4230708A (en) * 1977-10-20 1980-10-28 Stichting Rega V.Z.W. Therapeutic application of (S) -or (RS)-9-(2, 3-dihydroxypropyl) adenine for use as antiviral agents
US4221910A (en) * 1978-09-15 1980-09-09 Newport Pharmaceuticals International, Inc. 9-(Hydroxy alkyl)purines
IL64501A (en) * 1980-12-22 1985-07-31 Astra Laekemedel Ab 9-substituted 4-hydroxybutyl guanine derivatives,their preparation and antiviral use

Also Published As

Publication number Publication date
EP0103551A2 (en) 1984-03-21
GR78621B (xx) 1984-09-27
GB8316743D0 (en) 1983-07-20
AU1706083A (en) 1984-01-26
EP0103551A3 (en) 1984-06-13
ES8500942A1 (es) 1984-11-01
KR840005141A (ko) 1984-11-03
PT76902B (en) 1986-04-09
GB2122198B (en) 1985-11-06
IS2822A7 (is) 1986-02-28
JPS59501112A (ja) 1984-06-28
PH19399A (en) 1986-04-10
ATE18225T1 (de) 1986-03-15
NZ204640A (en) 1986-07-11
ZA834532B (en) 1984-03-28
WO1984000167A1 (en) 1984-01-19
EP0112353A1 (en) 1984-07-04
DE3362283D1 (en) 1986-04-03
EP0103551B1 (en) 1986-02-26
DD210274A5 (de) 1984-06-06
GB2122198A (en) 1984-01-11
ES523425A0 (es) 1984-11-01
PT76902A (en) 1983-07-01

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