SE8106138L - Forfarande for framstellning av en terapeutisk produkt - Google Patents

Forfarande for framstellning av en terapeutisk produkt

Info

Publication number
SE8106138L
SE8106138L SE8106138A SE8106138A SE8106138L SE 8106138 L SE8106138 L SE 8106138L SE 8106138 A SE8106138 A SE 8106138A SE 8106138 A SE8106138 A SE 8106138A SE 8106138 L SE8106138 L SE 8106138L
Authority
SE
Sweden
Prior art keywords
polymer
units
molecular weight
polymerization
therapeutic product
Prior art date
Application number
SE8106138A
Other languages
English (en)
Inventor
S Melamed
F E Boettner
Original Assignee
Rohm & Haas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rohm & Haas filed Critical Rohm & Haas
Publication of SE8106138L publication Critical patent/SE8106138L/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F12/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
    • C08F12/02—Monomers containing only one unsaturated aliphatic radical
    • C08F12/04—Monomers containing only one unsaturated aliphatic radical containing one ring
    • C08F12/14—Monomers containing only one unsaturated aliphatic radical containing one ring substituted by hetero atoms or groups containing heteroatoms
    • C08F12/30—Sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/795—Polymers containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/44—Preparation of metal salts or ammonium salts
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2800/00—Copolymer characterised by the proportions of the comonomers expressed
    • C08F2800/10—Copolymer characterised by the proportions of the comonomers expressed as molar percentages
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2800/00—Copolymer characterised by the proportions of the comonomers expressed
    • C08F2800/20—Copolymer characterised by the proportions of the comonomers expressed as weight or mass percentages

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (1)

PATENFKRAV CH,
1. FOrfarande for framstdllning am en terapeotisk produkt, kdnnetecknat am att man antingen (a) polymeriserar en monomer eller en moncmerblandning innehallande minst SO% vinylbensensulfonatenheter med formeln: X earl R Hr -H eller -CH3, och X Hr -H, alkyl eller halo, eller enheter am ett farmaceutiskt acceptabelt icke-texiskt salt ddrav, eller (b) bi1dar en polymerihillande minst SO% vinylbensenenheter med formeln: van i R och X har mean angiven betydelse, och utsdtter den For sulfonering sa att den slutliga polymeren innehaller minst SOS vinylbensensulfonatenheter, eller enheter av ett farmaceutiskt acceptabelt icke-toxiskt salt ddrav, varvid polymerisationen utfores under sadana betingelser att man erhaller en polymer med en viskositetsmedelmolekylvikt am fran 100 000 till 2 000 000, och varvid man antingen anvdnder sadana polymerisationsbetingelser att man erhaller en polymer, son innehaller mindre an 5 viktprocent polymer med en viskositetsmedelmolekylvikt am 20 000 eller lligre, eller att man ddrefter fran polymerprodukten avskiljer en sadan 'angel polymer med en viskositetsmedelmeleRy1vikt am 20 OHO mIter ngre att den resulterande terapeutiska prodei- ten innehaller re On S vikt nt am en sadan polymer med lig molekylvikt.
SE8106138A 1976-02-04 1981-10-16 Forfarande for framstellning av en terapeutisk produkt SE8106138L (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65520076A 1976-02-04 1976-02-04
US75269376A 1976-12-20 1976-12-20

Publications (1)

Publication Number Publication Date
SE8106138L true SE8106138L (sv) 1981-10-16

Family

ID=27096927

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7700670A SE430070B (sv) 1976-02-04 1977-01-21 Forfarande for framstellning av en terapeutisk produkt bestaende av en polymer med vinylbensensulfonatenheter
SE8106138A SE8106138L (sv) 1976-02-04 1981-10-16 Forfarande for framstellning av en terapeutisk produkt

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE7700670A SE430070B (sv) 1976-02-04 1977-01-21 Forfarande for framstellning av en terapeutisk produkt bestaende av en polymer med vinylbensensulfonatenheter

Country Status (10)

Country Link
JP (1) JPS5296748A (sv)
AU (1) AU514389B2 (sv)
CA (1) CA1114997A (sv)
DE (1) DE2704329A1 (sv)
DK (1) DK44777A (sv)
FR (1) FR2340330A1 (sv)
GB (1) GB1576016A (sv)
IE (1) IE44690B1 (sv)
NL (1) NL7701168A (sv)
SE (2) SE430070B (sv)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4395392A (en) * 1980-06-24 1983-07-26 Adria Laboratories Inc. Method for treating kidney stones
US4375461A (en) * 1980-07-25 1983-03-01 Johnson & Johnson Products, Inc. Sulfonated vinyl aromatic homopolymers and copolymers as dental plaque barriers
US4432967A (en) * 1982-06-25 1984-02-21 National Starch And Chemical Corp. Contraceptive composition
EP0579153B1 (en) * 1992-07-13 1998-04-08 Tosoh Corporation Process for producing tertiary alcohols
US6270755B1 (en) 1999-05-13 2001-08-07 Geltex Pharmaceuticals, Inc. Anionic polymers as toxin binders
EP1800686A3 (en) * 1999-05-13 2009-12-30 Genzyme Corporation Anionic polymers as toxin binders and antibacterial agents
US6290946B1 (en) 1999-05-13 2001-09-18 Geltex Pharmaceuticals, Inc. Anionic polymers as toxin binders and antibacterial agents
CA2314494A1 (en) 2000-05-02 2001-11-02 Geltex Pharmaceuticals, Inc. Anionic polymers as species specific antibacterial agents
WO2003099881A1 (en) * 2001-01-11 2003-12-04 Sony Corporation Ion-conductive polymer, solid polyelectrolyte, and cell employing the same
WO2004009100A1 (en) * 2002-07-22 2004-01-29 Genzyme Corporation Poly (potassium and sodium styrene sulfonate), its manufacture and its uses
AU2003903547A0 (en) * 2003-07-10 2003-07-24 Neoferma Australia Pty Ltd Structures and methods of waterproofing same
JP6271378B2 (ja) * 2014-09-05 2018-01-31 信越化学工業株式会社 導電性ポリマー用高分子化合物及びその製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3310481A (en) * 1962-09-10 1967-03-21 Dow Chemical Co Removal of residual monomeric sulfonates from polymerizates thereof
JPS4936644A (sv) * 1972-08-15 1974-04-05

Also Published As

Publication number Publication date
SE430070B (sv) 1983-10-17
FR2340330A1 (fr) 1977-09-02
DE2704329A1 (de) 1977-08-18
SE7700670L (sv) 1977-08-05
FR2340330B1 (sv) 1981-05-29
SE426835B (sv) 1983-02-14
IE44690L (en) 1977-08-04
IE44690B1 (en) 1982-02-24
CA1114997A (en) 1981-12-22
JPS5296748A (en) 1977-08-13
DK44777A (da) 1977-08-05
AU514389B2 (en) 1981-02-05
AU2193477A (en) 1978-08-10
GB1576016A (en) 1980-10-01
NL7701168A (nl) 1977-08-08

Similar Documents

Publication Publication Date Title
SE8106138L (sv) Forfarande for framstellning av en terapeutisk produkt
DE69607747D1 (de) Vernetzte polymere enthaltend salzstrukturen
IE42682L (en) Preparation of vinyl chloride polymers
SU795489A3 (ru) Способ получени частичногидРОлизОВАННОгО пОлиВиНилАцЕТАТА
EP0110356B1 (en) Process for producing a high purity cyclized polymer of isoprene
ES477510A1 (es) Un procedimiento para la preparacion de derivados de imidilotriciclicos.
JPS51125471A (en) Preparation of high molecular weight polymers resistant to oxidation
Miura et al. Vinyl polymerization. 280. Anionic polymerization of acryloyl‐and methacryloyl verdazyls
JPS51129475A (en) A process for polymerizing monomers
JPS52151383A (en) Preparation of styrene polymers
SU451715A1 (ru) Способ получени полиизоциануратов
JPS5548201A (en) Graft polymer of polysaccharide ester and its manufacture
IE42687L (en) Continuous manufacture of polymers of vinyl chloride
ES8400125A1 (es) Procedimiento para la obtencion de cloruro de polivinilo transparente y antiestatico
RU731759C (ru) Способ получения полиэтиленметилдиэтоксисиланов
JPS5770102A (en) Production of high-purity cylized diene polymer
SU455973A1 (ru) Способ получени хлорсодержащих полимеров
SU575358A1 (ru) Способ получени сополимеров
SU1008211A1 (ru) Способ получени сополимера 2,3-дихлорбутадиена-1,3
SE402463B (sv) Forfarande for framstellning av vetkseformiga polymerer med mycket hog viskositet genom polymerisation av n-olefinblandningar eller enskilda linjera n-alfaolefiner i nervaro av ett katalysatorkomplex
JPS5284269A (en) Preparation of super-high-molecular-weight polymers
JPS52102389A (en) Preparation of emulsion compositions
SU385975A1 (ru) Способ получения водорастворимых (пюлиэлектролитов
SU513990A1 (ru) Способ получени поли-1,1,2-трихлорбутадиена-1,3
SU440378A1 (ru) Способ получени блок-сополимеров

Legal Events

Date Code Title Description
NAV Patent application has lapsed

Ref document number: 8106138-4

Format of ref document f/p: F