SE8004934L - 5-(-pyridinyl)-2(lh)-pyridioner, anvendbara sasom kardiotoniska medel, samt framstellning derav - Google Patents

5-(-pyridinyl)-2(lh)-pyridioner, anvendbara sasom kardiotoniska medel, samt framstellning derav

Info

Publication number
SE8004934L
SE8004934L SE8004934A SE8004934A SE8004934L SE 8004934 L SE8004934 L SE 8004934L SE 8004934 A SE8004934 A SE 8004934A SE 8004934 A SE8004934 A SE 8004934A SE 8004934 L SE8004934 L SE 8004934L
Authority
SE
Sweden
Prior art keywords
pyridinyl
pyridinone
hydroxymethyl
hydroxy
pyridions
Prior art date
Application number
SE8004934A
Other languages
English (en)
Inventor
G Y Lesher
Jr C J Opalka
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of SE8004934L publication Critical patent/SE8004934L/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/69Two or more oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE8004934A 1979-09-10 1980-07-03 5-(-pyridinyl)-2(lh)-pyridioner, anvendbara sasom kardiotoniska medel, samt framstellning derav SE8004934L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/073,885 US4225601A (en) 1979-09-10 1979-09-10 3-Hydroxy or hydroxymethyl-5-(4-pyridinyl)2(1H)-pyridinones, useful as cardiotonic agents and their preparation

Publications (1)

Publication Number Publication Date
SE8004934L true SE8004934L (sv) 1981-03-11

Family

ID=22116385

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8004934A SE8004934L (sv) 1979-09-10 1980-07-03 5-(-pyridinyl)-2(lh)-pyridioner, anvendbara sasom kardiotoniska medel, samt framstellning derav

Country Status (21)

Country Link
US (1) US4225601A (sv)
JP (1) JPS5668670A (sv)
KR (1) KR830003470A (sv)
AR (1) AR223716A1 (sv)
AU (1) AU6003080A (sv)
BE (1) BE884329A (sv)
DE (1) DE3027901A1 (sv)
DK (1) DK314180A (sv)
ES (1) ES493583A0 (sv)
FI (1) FI802298A (sv)
FR (1) FR2465722A1 (sv)
GB (1) GB2058751A (sv)
IL (1) IL60360A0 (sv)
IT (1) IT1132192B (sv)
LU (1) LU82650A1 (sv)
NL (1) NL8004126A (sv)
NO (1) NO802138L (sv)
NZ (1) NZ194106A (sv)
PT (1) PT71427A (sv)
SE (1) SE8004934L (sv)
ZA (1) ZA803679B (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4361569A (en) * 1981-08-26 1982-11-30 Sterling Drug Inc. 3-(Hydroxy or hydroxymethyl)-6-methyl-5-(4-pyridinyl)-2(1H)-pyridinone and cardiotonic use thereof
US4432979A (en) * 1981-10-26 1984-02-21 William H. Rorer, Inc. Pyridone compounds
US4463008A (en) * 1982-11-10 1984-07-31 Sterling Drug Inc. 2-Alkoxy-5-(pyridinyl)pyridines and cardiotonic use thereof
US6068581A (en) * 1998-04-29 2000-05-30 Timm Medical Technologies, Inc. Method and apparatus for testing and exercising pelvic muscles
EP2542077A4 (en) * 2010-03-04 2013-08-21 Merck Sharp & Dohme CATECHOL O-METHYL TRANSFERASE INHIBITORS AND USE THEREOF IN THE TREATMENT OF PSYCHOTIC DISORDERS

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4072746A (en) * 1975-10-14 1978-02-07 Sterling Drug Inc. 3-Amino-5-(pyridinyl)-2(1H)-pyridinones

Also Published As

Publication number Publication date
BE884329A (fr) 1981-01-16
FR2465722A1 (fr) 1981-03-27
IT1132192B (it) 1986-06-25
DK314180A (da) 1981-03-11
US4225601A (en) 1980-09-30
GB2058751A (en) 1981-04-15
PT71427A (en) 1980-07-01
ES8106514A1 (es) 1981-07-01
AR223716A1 (es) 1981-09-15
IL60360A0 (en) 1980-09-16
LU82650A1 (fr) 1981-03-24
NZ194106A (en) 1982-03-30
ZA803679B (en) 1981-06-24
NO802138L (no) 1981-03-11
FI802298A (fi) 1981-03-11
ES493583A0 (es) 1981-07-01
NL8004126A (nl) 1981-03-12
IT8023422A0 (it) 1980-07-14
KR830003470A (ko) 1983-06-20
AU6003080A (en) 1981-03-19
JPS5668670A (en) 1981-06-09
DE3027901A1 (de) 1981-03-26

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