SE7908896L - cephalosporin - Google Patents
cephalosporinInfo
- Publication number
- SE7908896L SE7908896L SE7908896A SE7908896A SE7908896L SE 7908896 L SE7908896 L SE 7908896L SE 7908896 A SE7908896 A SE 7908896A SE 7908896 A SE7908896 A SE 7908896A SE 7908896 L SE7908896 L SE 7908896L
- Authority
- SE
- Sweden
- Prior art keywords
- antibiotics
- alkyl group
- activity against
- high activity
- cephalosporin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
Abstract
Cephalosporin antibiotics of general formula <IMAGE> (wherein R<a> and R<b>, which may be the same or different, each represent a C1-4 alkyl group or R<a> and R<b> together with the carbon atom to which they are attached from a C3-7 cycloalkylidene group; and R<1> represents a C1-4 alkyl group) exhibit broad spectrum antibiotic activity with unusually high activity against strains of Pseudomonas organisms as well as high activity against various members of the Enterobacteriaceae. The invention also includes the non-toxic salts and non-toxic metabolically labile esters of compounds of formula (I). Also described are compositions containing the antibiotics of the invention and processes for the preparation of the antibiotics.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7842165 | 1978-10-27 | ||
GB7842164 | 1978-10-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
SE7908896L true SE7908896L (en) | 1980-04-28 |
Family
ID=26269350
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7908896A SE7908896L (en) | 1978-10-27 | 1979-10-26 | cephalosporin |
Country Status (13)
Country | Link |
---|---|
AT (1) | AT369009B (en) |
CA (1) | CA1130280A (en) |
CH (1) | CH644868A5 (en) |
DE (1) | DE2943427A1 (en) |
DK (1) | DK452679A (en) |
ES (3) | ES485441A1 (en) |
FR (1) | FR2439786A1 (en) |
GB (1) | GB2036724B (en) |
IE (1) | IE49100B1 (en) |
IT (1) | IT1126819B (en) |
NL (1) | NL7907882A (en) |
NZ (1) | NZ191937A (en) |
SE (1) | SE7908896L (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR78245B (en) * | 1980-09-12 | 1984-09-26 | Ciba Geigy Ag | |
KR860000487B1 (en) * | 1980-09-25 | 1986-04-30 | 도야마 가가꾸 고오교 가부시끼가이샤 | Process for preparing cephalosporins |
NZ198350A (en) * | 1980-09-25 | 1985-02-28 | Toyama Chemical Co Ltd | Cephalosporins and intermediates;pharmaceutical compositions |
EP0062321B1 (en) * | 1981-04-03 | 1989-03-01 | Fujisawa Pharmaceutical Co., Ltd. | New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds |
FR2533216A1 (en) * | 1982-09-22 | 1984-03-23 | Toyama Chemical Co Ltd | New cephalosporins and their salts. |
DE3336757A1 (en) * | 1983-10-08 | 1985-04-25 | Hoechst Ag, 6230 Frankfurt | CEPHALOSPORINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION |
CA1299564C (en) * | 1985-09-03 | 1992-04-28 | Akihiro Shimabayashi | Cephalosporin derivative |
US4826834A (en) * | 1985-09-27 | 1989-05-02 | Takeda Chemical Industries, Ltd. | Cephem compounds |
CN86107947A (en) * | 1985-11-22 | 1987-05-27 | 藤沢药品工业株式会社 | New cephem compounds and preparation method thereof |
KR930009796B1 (en) * | 1991-05-25 | 1993-10-11 | 주식회사 대웅제약 | Cephalosporin derivatives |
CN114105903B (en) * | 2021-12-16 | 2023-06-27 | 河北合佳医药科技集团股份有限公司 | Preparation method of high-purity desmethyl aminothiaoxime |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1496757A (en) * | 1973-12-21 | 1978-01-05 | Glaxo Lab Ltd | Cephalosporin derivatives |
DE2460537A1 (en) * | 1973-12-21 | 1975-07-03 | Glaxo Lab Ltd | CEPHALOSPORIN ANTIBIOTICS |
NO750810L (en) * | 1974-03-20 | 1975-09-23 | Hoeganaes Ab | |
DK154939C (en) * | 1974-12-19 | 1989-06-12 | Takeda Chemical Industries Ltd | METHOD OF ANALOGUE FOR THE PREPARATION OF THIAZOLYLACETAMIDO-CEPHEM COMPOUNDS OR PHARMACEUTICAL ACCEPTABLE SALTS OR ESTERS THEREOF |
-
1979
- 1979-10-26 GB GB7937305A patent/GB2036724B/en not_active Expired
- 1979-10-26 ES ES485441A patent/ES485441A1/en not_active Expired
- 1979-10-26 NZ NZ191937A patent/NZ191937A/en unknown
- 1979-10-26 DK DK452679A patent/DK452679A/en not_active Application Discontinuation
- 1979-10-26 DE DE19792943427 patent/DE2943427A1/en not_active Withdrawn
- 1979-10-26 NL NL7907882A patent/NL7907882A/en not_active Application Discontinuation
- 1979-10-26 CA CA338,576A patent/CA1130280A/en not_active Expired
- 1979-10-26 IE IE2070/79A patent/IE49100B1/en unknown
- 1979-10-26 FR FR7926634A patent/FR2439786A1/en active Granted
- 1979-10-26 ES ES485439A patent/ES485439A1/en not_active Expired
- 1979-10-26 CH CH964579A patent/CH644868A5/en not_active IP Right Cessation
- 1979-10-26 ES ES485440A patent/ES485440A1/en not_active Expired
- 1979-10-26 SE SE7908896A patent/SE7908896L/en not_active Application Discontinuation
- 1979-10-26 IT IT50680/79A patent/IT1126819B/en active
- 1979-10-29 AT AT0698079A patent/AT369009B/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IT7950680A0 (en) | 1979-10-26 |
NZ191937A (en) | 1982-09-07 |
GB2036724A (en) | 1980-07-02 |
GB2036724B (en) | 1983-01-19 |
ES485441A1 (en) | 1980-07-01 |
ATA698079A (en) | 1982-04-15 |
DK452679A (en) | 1980-04-28 |
NL7907882A (en) | 1980-04-29 |
FR2439786B1 (en) | 1983-05-20 |
AT369009B (en) | 1982-11-25 |
IE49100B1 (en) | 1985-07-24 |
FR2439786A1 (en) | 1980-05-23 |
CA1130280A (en) | 1982-08-24 |
DE2943427A1 (en) | 1980-05-08 |
IE792070L (en) | 1980-04-27 |
IT1126819B (en) | 1986-05-21 |
CH644868A5 (en) | 1984-08-31 |
ES485439A1 (en) | 1980-07-01 |
ES485440A1 (en) | 1980-07-01 |
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Legal Events
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