SE7908895L - cephalosporin - Google Patents

cephalosporin

Info

Publication number
SE7908895L
SE7908895L SE7908895A SE7908895A SE7908895L SE 7908895 L SE7908895 L SE 7908895L SE 7908895 A SE7908895 A SE 7908895A SE 7908895 A SE7908895 A SE 7908895A SE 7908895 L SE7908895 L SE 7908895L
Authority
SE
Sweden
Prior art keywords
antibiotics
alkyl group
different
same
activity against
Prior art date
Application number
SE7908895A
Other languages
Swedish (sv)
Inventor
C H O'callaghan
B E Ayres
D G H Livermore
C E Newall
D R Sutherland
N G Weir
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of SE7908895L publication Critical patent/SE7908895L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Cephalosporin antibiotics of general formula <IMAGE> (wherein R<a> and R<b>, which may be the same or different, each represent a C1-4 alkyl group or R<a> and R<b> together with the carbon atom to which they are attached form a C3-7 cycloalkylidene group; and R<1>, R<2> and R<3>, which may be the same or different, each represents a C1-4 alkyl group) exhibit broad spectrum antibiotic activity with unusually high activity against strains of Pseudomonas organisms as well as high activity against various members of the Enterobacteriaceae. The invention also includes the non-toxic salts and non-toxic metabolically labile esters of compounds of formula (I). Also described are compositions containing the antibiotics of the invention and processes for the preparation of the antibiotics.
SE7908895A 1978-10-27 1979-10-26 cephalosporin SE7908895L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7842163 1978-10-27
GB7842162 1978-10-27

Publications (1)

Publication Number Publication Date
SE7908895L true SE7908895L (en) 1980-04-28

Family

ID=26269349

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7908895A SE7908895L (en) 1978-10-27 1979-10-26 cephalosporin

Country Status (13)

Country Link
AT (1) AT367765B (en)
CA (1) CA1131618A (en)
CH (1) CH644867A5 (en)
DE (1) DE2943437A1 (en)
DK (1) DK452579A (en)
ES (3) ES485433A1 (en)
FR (1) FR2439787A1 (en)
GB (1) GB2040921B (en)
IE (1) IE49099B1 (en)
IT (1) IT1164746B (en)
NL (1) NL7907881A (en)
NZ (1) NZ191936A (en)
SE (1) SE7908895L (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR78245B (en) * 1980-09-12 1984-09-26 Ciba Geigy Ag
CA1213882A (en) * 1982-03-04 1986-11-12 Jun Okumura Cephalosporins
US4457929A (en) * 1982-03-29 1984-07-03 Bristol-Myers Company 3-Quaternary ammonium methyl)-substituted cephalosporin derivatives
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives
DE3409431A1 (en) * 1983-10-08 1985-04-18 Hoechst Ag, 6230 Frankfurt CEPHALOSPORINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION
DE3404906A1 (en) * 1984-02-11 1985-08-14 Bayer Ag, 5090 Leverkusen 1-OXADETHIACEPHALOSPORINE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF

Also Published As

Publication number Publication date
IT7950681A0 (en) 1979-10-26
ATA698179A (en) 1981-12-15
GB2040921A (en) 1980-09-03
IT1164746B (en) 1987-04-15
ES485434A1 (en) 1980-07-01
NZ191936A (en) 1982-09-07
DK452579A (en) 1980-04-28
AT367765B (en) 1982-07-26
NL7907881A (en) 1980-04-29
FR2439787B1 (en) 1983-04-29
ES485433A1 (en) 1980-07-01
GB2040921B (en) 1982-12-22
DE2943437A1 (en) 1980-05-08
ES485435A1 (en) 1980-07-01
IE792069L (en) 1980-04-27
FR2439787A1 (en) 1980-05-23
IE49099B1 (en) 1985-07-24
CA1131618A (en) 1982-09-14
CH644867A5 (en) 1984-08-31

Similar Documents

Publication Publication Date Title
SE7904576L (en) cephalosporin antibiotics
SE7904577L (en) cephalosporin antibiotics
SE7908896L (en) cephalosporin
SE7909401L (en) cephalosporin antibiotics
SE7909501L (en) Cephalosporin antibiotics
SE7908895L (en) cephalosporin
SE8001423L (en) cephalosporin antibiotics
SE8002217L (en) cephalosporin antibiotics
FI833839A (en) FOERFARANDE FOER FRAMSTAELLNING AV TERAPEUTISKT AKTIVA KEFALOSPORINDERIVAT
SE8303727D0 (en) cephalosporin antibiotics
IE791026L (en) Cephalosporin derivatives.
SE8306475D0 (en) cephalosporin antibiotics

Legal Events

Date Code Title Description
NAV Patent application has lapsed

Ref document number: 7908895-1