SE7811459L - Forfarande for framstellning av oligonukleotider genom triesterbildning - Google Patents

Forfarande for framstellning av oligonukleotider genom triesterbildning

Info

Publication number
SE7811459L
SE7811459L SE7811459A SE7811459A SE7811459L SE 7811459 L SE7811459 L SE 7811459L SE 7811459 A SE7811459 A SE 7811459A SE 7811459 A SE7811459 A SE 7811459A SE 7811459 L SE7811459 L SE 7811459L
Authority
SE
Sweden
Prior art keywords
oligonucleotids
procedure
production
triester
formation
Prior art date
Application number
SE7811459A
Other languages
English (en)
Swedish (sv)
Inventor
K Itakura
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of SE7811459L publication Critical patent/SE7811459L/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • C07H19/10Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • C07H19/20Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SE7811459A 1977-11-08 1978-11-06 Forfarande for framstellning av oligonukleotider genom triesterbildning SE7811459L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84960877A 1977-11-08 1977-11-08

Publications (1)

Publication Number Publication Date
SE7811459L true SE7811459L (sv) 1979-05-09

Family

ID=25306107

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7811459A SE7811459L (sv) 1977-11-08 1978-11-06 Forfarande for framstellning av oligonukleotider genom triesterbildning

Country Status (22)

Country Link
EP (1) EP0002322A3 (pl)
JP (1) JPS5473787A (pl)
AU (1) AU4136078A (pl)
BE (1) BE871781A (pl)
BR (1) BR7807288A (pl)
DD (1) DD141836A5 (pl)
DE (1) DE2848054A1 (pl)
DK (1) DK493678A (pl)
ES (1) ES474850A1 (pl)
FI (1) FI783364A7 (pl)
FR (1) FR2407939A1 (pl)
GB (1) GB2007670A (pl)
IL (1) IL55893A0 (pl)
LU (1) LU80483A1 (pl)
NL (1) NL7811043A (pl)
NO (1) NO783721L (pl)
OA (1) OA06003A (pl)
PL (1) PL210786A1 (pl)
PT (1) PT68754A (pl)
SE (1) SE7811459L (pl)
ZA (1) ZA786303B (pl)
ZM (1) ZM9478A1 (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR7807290A (pt) * 1977-11-08 1979-06-12 Genentech Inc Plasmideo,processo para producao de um polipeptido especifico veiculo clonal,cultura bacteriana transformante,processo para produzir uma substancia imunogenica processo para preparar um gene estrutural,e polidesoxirribonucleotido de faixa dupla
US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
US4474947A (en) * 1982-04-08 1984-10-02 Biosearch Benzazolides and their employment in phosphate ester oligonucleotide synthesis processes
JPS61152695A (ja) * 1984-12-26 1986-07-11 Nippon Shinyaku Co Ltd 長鎖dnaの合成法
KR101881596B1 (ko) 2008-12-02 2018-07-24 웨이브 라이프 사이언시스 재팬 인코포레이티드 인 원자 변형된 핵산의 합성 방법
RU2612521C2 (ru) 2009-07-06 2017-03-09 Онтории, Инк. Новые пролекарства нуклеиновых кислот и способы их применения
JP5868324B2 (ja) 2010-09-24 2016-02-24 株式会社Wave Life Sciences Japan 不斉補助基
BR112014001244A2 (pt) 2011-07-19 2017-02-21 Wave Life Sciences Pte Ltd métodos para a síntese de ácidos nucléicos funcionalizados
ES2862073T3 (es) 2012-07-13 2021-10-06 Wave Life Sciences Ltd Grupo auxiliar asimétrico
BR112015000723A2 (pt) 2012-07-13 2017-06-27 Shin Nippon Biomedical Laboratories Ltd adjuvante de ácido nucléico quiral
CN112007045A (zh) 2012-07-13 2020-12-01 波涛生命科学有限公司 手性控制
EP3095459A4 (en) 2014-01-15 2017-08-23 Shin Nippon Biomedical Laboratories, Ltd. Chiral nucleic acid adjuvant having antitumor effect and antitumor agent
EP3095460A4 (en) 2014-01-15 2017-08-23 Shin Nippon Biomedical Laboratories, Ltd. Chiral nucleic acid adjuvant having anti-allergic activity, and anti-allergic agent
US10144933B2 (en) 2014-01-15 2018-12-04 Shin Nippon Biomedical Laboratories, Ltd. Chiral nucleic acid adjuvant having immunity induction activity, and immunity induction activator
CN113278617A (zh) 2014-01-16 2021-08-20 波涛生命科学有限公司 手性设计

Also Published As

Publication number Publication date
OA06003A (fr) 1981-06-30
EP0002322A2 (en) 1979-06-13
NO783721L (no) 1979-05-09
FR2407939A1 (fr) 1979-06-01
LU80483A1 (fr) 1979-03-22
PL210786A1 (pl) 1979-07-16
PT68754A (en) 1978-12-01
NL7811043A (nl) 1979-05-10
AU4136078A (en) 1979-05-17
ZA786303B (en) 1979-10-31
DD141836A5 (de) 1980-05-21
ZM9478A1 (en) 1980-03-21
BE871781A (fr) 1979-05-07
IL55893A0 (en) 1979-01-31
FI783364A7 (fi) 1979-05-09
JPS5473787A (en) 1979-06-13
GB2007670A (en) 1979-05-23
EP0002322A3 (en) 1979-06-27
ES474850A1 (es) 1979-12-01
DE2848054A1 (de) 1979-05-10
DK493678A (da) 1979-07-12
BR7807288A (pt) 1979-06-12

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