SE7804307L - Forfarande for framstellning av 2-(2,2-diarylalkyl)-1-azabicyklo(2.2.2)oktan och beslektade foreningar - Google Patents
Forfarande for framstellning av 2-(2,2-diarylalkyl)-1-azabicyklo(2.2.2)oktan och beslektade foreningarInfo
- Publication number
- SE7804307L SE7804307L SE7804307A SE7804307A SE7804307L SE 7804307 L SE7804307 L SE 7804307L SE 7804307 A SE7804307 A SE 7804307A SE 7804307 A SE7804307 A SE 7804307A SE 7804307 L SE7804307 L SE 7804307L
- Authority
- SE
- Sweden
- Prior art keywords
- diarylalkyl
- azabicyclo
- octane
- procedure
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/788,189 US4125531A (en) | 1977-04-18 | 1977-04-18 | 2-Substituted-1-azabicyclo[2.2.2]octanes |
Publications (1)
Publication Number | Publication Date |
---|---|
SE7804307L true SE7804307L (sv) | 1978-10-19 |
Family
ID=25143721
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7804307A SE7804307L (sv) | 1977-04-18 | 1978-04-17 | Forfarande for framstellning av 2-(2,2-diarylalkyl)-1-azabicyklo(2.2.2)oktan och beslektade foreningar |
Country Status (19)
Country | Link |
---|---|
US (1) | US4125531A (xx) |
JP (1) | JPS53132596A (xx) |
AT (1) | AT357553B (xx) |
AU (1) | AU3516178A (xx) |
BE (1) | BE866031A (xx) |
DE (1) | DE2816633A1 (xx) |
DK (1) | DK166978A (xx) |
ES (1) | ES468874A1 (xx) |
FI (1) | FI781161A (xx) |
FR (1) | FR2387980A1 (xx) |
GB (1) | GB1569249A (xx) |
IE (1) | IE46737B1 (xx) |
IL (1) | IL54519A0 (xx) |
NL (1) | NL7804145A (xx) |
NO (1) | NO781333L (xx) |
NZ (1) | NZ186991A (xx) |
PT (1) | PT67910B (xx) |
SE (1) | SE7804307L (xx) |
ZA (1) | ZA782212B (xx) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4203990A (en) * | 1979-04-30 | 1980-05-20 | G. D. Searle & Co. | Anti-diarrheal 2-substituted quinuclidines |
US4203989A (en) * | 1979-04-30 | 1980-05-20 | G. D. Searle & Co. | Anti-diarrheal diaryl-(1-azabicyclo(2.2.2)octan-2-yl)-alkanols and related compounds |
US4599344A (en) * | 1984-10-31 | 1986-07-08 | Schering A.G. | Quinuclidines and quinuclidinium salts as antiarrhythmic agents |
CA2022886A1 (en) * | 1989-08-08 | 1991-02-09 | Raymond Baker | Substituted pyridines, their preparation, formulations and use in dementia |
EP0499313B1 (en) * | 1991-02-11 | 1997-06-11 | MERCK SHARP & DOHME LTD. | Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy |
US6190691B1 (en) | 1994-04-12 | 2001-02-20 | Adolor Corporation | Methods for treating inflammatory conditions |
US5962477A (en) * | 1994-04-12 | 1999-10-05 | Adolor Corporation | Screening methods for cytokine inhibitors |
US5849761A (en) | 1995-09-12 | 1998-12-15 | Regents Of The University Of California | Peripherally active anti-hyperalgesic opiates |
US6573282B1 (en) | 1995-09-12 | 2003-06-03 | Adolor Corporation | Peripherally active anti-hyperalgesic opiates |
US5849762A (en) * | 1997-07-14 | 1998-12-15 | Adolor Corporation | Peripherally acting anti-pruritic opiates |
US6353004B1 (en) | 1997-07-14 | 2002-03-05 | Adolor Coporation | Peripherally acting anti-pruritic opiates |
CN104383542B (zh) | 2003-04-08 | 2017-09-26 | 普罗热尼奇制药公司 | 包含甲基纳曲酮的药物配方 |
AR057035A1 (es) | 2005-05-25 | 2007-11-14 | Progenics Pharm Inc | SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS |
AR057325A1 (es) | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
EP3263571B2 (en) | 2007-03-29 | 2023-08-23 | Progenics Pharmaceuticals, Inc. | Crystal form of (r)-n-methylnaltrexone bromide and uses thereof |
US8338446B2 (en) | 2007-03-29 | 2012-12-25 | Wyeth Llc | Peripheral opioid receptor antagonists and uses thereof |
PE20130480A1 (es) | 2007-03-29 | 2013-05-08 | Progenics Pharm Inc | Compuestos heterociclicos como antagonistas del receptor opioide periferico |
WO2009099411A1 (en) | 2008-02-06 | 2009-08-13 | Progenics Pharmaceuticals, Inc. | Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone |
CA2676881C (en) | 2008-09-30 | 2017-04-25 | Wyeth | Peripheral opioid receptor antagonists and uses thereof |
CN110372571B (zh) | 2018-04-12 | 2022-11-15 | 中国科学院大连化学物理研究所 | 一种2-(2,2-二芳基乙基)-环胺衍生物或盐及合成和应用与组合物 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3506672A (en) * | 1968-03-29 | 1970-04-14 | Aldrich Chem Co Inc | 2-(4,4'-dihalo)-benzhydryl-3-quinuclidinols |
SU495310A1 (ru) * | 1974-03-05 | 1975-12-15 | Всесоюзный Научно-Исследовательский Химико-Фармацевтический Институт Им.С.Орджоникидзе | Хинуклидил-3-диарал(гетерил) карбинолы, про вл ющие антигистаминную, антисеротониновую и антиаллергическую активность и способ их получени |
US4013667A (en) * | 1976-03-08 | 1977-03-22 | G. D. Searle & Co. | 2,2-Diaryl-3-(1-azabicyclo[2.2.2]oct-2-yl)propionamides and intermediates thereto |
-
1977
- 1977-04-18 US US05/788,189 patent/US4125531A/en not_active Expired - Lifetime
-
1978
- 1978-04-17 AU AU35161/78A patent/AU3516178A/en active Pending
- 1978-04-17 DE DE19782816633 patent/DE2816633A1/de not_active Withdrawn
- 1978-04-17 DK DK166978A patent/DK166978A/da not_active IP Right Cessation
- 1978-04-17 PT PT67910A patent/PT67910B/pt unknown
- 1978-04-17 IL IL54519A patent/IL54519A0/xx unknown
- 1978-04-17 NZ NZ186991A patent/NZ186991A/xx unknown
- 1978-04-17 FI FI781161A patent/FI781161A/fi not_active Application Discontinuation
- 1978-04-17 SE SE7804307A patent/SE7804307L/xx unknown
- 1978-04-17 GB GB14965/78A patent/GB1569249A/en not_active Expired
- 1978-04-17 IE IE745/78A patent/IE46737B1/en unknown
- 1978-04-17 AT AT266178A patent/AT357553B/de not_active IP Right Cessation
- 1978-04-17 ES ES468874A patent/ES468874A1/es not_active Expired
- 1978-04-17 BE BE186827A patent/BE866031A/xx unknown
- 1978-04-17 NO NO781333A patent/NO781333L/no unknown
- 1978-04-18 NL NL7804145A patent/NL7804145A/xx not_active Application Discontinuation
- 1978-04-18 ZA ZA00782212A patent/ZA782212B/xx unknown
- 1978-04-18 FR FR7811370A patent/FR2387980A1/fr not_active Withdrawn
- 1978-04-18 JP JP4578878A patent/JPS53132596A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
NO781333L (no) | 1978-10-19 |
AU3516178A (en) | 1979-10-25 |
FR2387980A1 (fr) | 1978-11-17 |
PT67910A (en) | 1978-05-01 |
BE866031A (fr) | 1978-10-17 |
FI781161A (fi) | 1978-10-19 |
AT357553B (de) | 1980-07-25 |
DE2816633A1 (de) | 1978-10-19 |
NZ186991A (en) | 1979-12-11 |
IE46737B1 (en) | 1983-09-07 |
PT67910B (en) | 1979-11-14 |
ZA782212B (en) | 1979-11-28 |
IE780745L (en) | 1978-10-18 |
US4125531A (en) | 1978-11-14 |
ES468874A1 (es) | 1978-12-01 |
JPS53132596A (en) | 1978-11-18 |
GB1569249A (en) | 1980-06-11 |
ATA266178A (de) | 1979-12-15 |
NL7804145A (nl) | 1978-10-20 |
DK166978A (da) | 1978-10-19 |
IL54519A0 (en) | 1978-07-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO794327L (no) | Fremgangsmaate ved fremstilling av nye peptidylargininaldehyd-derivater. | |
NO803851L (no) | Fremgangsmaate til fremstilling av 4,1`,6`-triklor-4,1`,6`-trideoksy-galaktosukrose | |
SE7804307L (sv) | Forfarande for framstellning av 2-(2,2-diarylalkyl)-1-azabicyklo(2.2.2)oktan och beslektade foreningar | |
NO155434C (no) | Fremgangsmaate for fremstilling av forfalskningssikre dokumenter. | |
SE434946B (sv) | Forfarande for framstellning av acylsackariner och acyl-3-oxo-1,2-densisotiazoliner | |
SE7813441L (sv) | N-substituerade omega-aminoalkanoyl-omega-aminoalkansyror, anvendning derav och forfaranden for framstellning derav samt lekemedel innehallande dessa foreningar | |
NO148959C (no) | Fremgangsmaate ved fremstilling av tumor-motvirkende antracyklinglykosidantibiotika, betegnet ma 144 | |
SE7804400L (sv) | Cefalosporinforeningar och forfarande for framstellning derav | |
NO800338L (no) | Fremgangsmaate ved fremstilling av nye 4-(nafthylmethyl)piperidinderivater. | |
NO149957C (no) | Fremgangsmaate for fremstilling av 4-(6`-metoksy-2`-naftyl)butan-2-on. | |
NO800627L (no) | Fremgangsmaate for fremstilling av lateks. | |
NO156086C (no) | Analogifremgangsmaate for fremstilling av substituerte heterocykliske fenoksyaminer. | |
FI793367A (fi) | Foerfarande foer framstaellning av 1,2,3-tiadiazol-5-yl-urinaemnen | |
NO153431C (no) | Fremgangsmaate ved fremstilling av 6alfa-halogen-3-keto-delta1,4-pregnadiener. | |
RO77485A (ro) | Procedeu pentru prepararea 1,2,3-tiadiazol-3-in-5-ilidenureelor | |
NO153853C (no) | Fremgangsmaate for fremstilling av 17beta-hydroksy-17alfa-pregn-5-en-21-karboksylsyre-gamma-laktoner. | |
SE436026B (sv) | Forfarande for framstellning av 13,14-dehydroprostaglandiner | |
NO152645C (no) | Fremgangsmaate for fremstilling av klordioksyd. | |
NO794199L (no) | Fremgangsmaate for fremstilling av spinnflor. | |
RO81212A (ro) | Procedeu pentru prepararea unor 2',6'-dialchil-n-(alcoximetil)2-cloracetanilide | |
NO801142L (no) | Fremgangsmaate til fremstilling av klordioksyd. | |
NO155539C (no) | Analogifremgangsmaate for fremstilling av terapeutisk virksomme isokinolinderivater. | |
SE7804878L (sv) | Forfarande for framstellning av 1,2-dikloretan | |
NO152840C (no) | Fremgangsmaate for fremstilling av dibenzyletere. | |
RO75739A (ro) | Procedeu pentru prepararea unor carbamoil triazolil-o,n-acetali |