SE7711381L - Forfarande for framstellning av n1-(2'-furanidyl)-5-fluoruracil - Google Patents
Forfarande for framstellning av n1-(2'-furanidyl)-5-fluoruracilInfo
- Publication number
- SE7711381L SE7711381L SE7711381A SE7711381A SE7711381L SE 7711381 L SE7711381 L SE 7711381L SE 7711381 A SE7711381 A SE 7711381A SE 7711381 A SE7711381 A SE 7711381A SE 7711381 L SE7711381 L SE 7711381L
- Authority
- SE
- Sweden
- Prior art keywords
- uracil
- furanidyl
- fluoro
- fluoruracil
- procedure
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 229960002949 fluorouracil Drugs 0.000 title abstract 2
- ISAKRJDGNUQOIC-UHFFFAOYSA-N Uracil Chemical compound O=C1C=CNC(=O)N1 ISAKRJDGNUQOIC-UHFFFAOYSA-N 0.000 abstract 2
- 239000003054 catalyst Substances 0.000 abstract 2
- JKTCBAGSMQIFNL-UHFFFAOYSA-N 2,3-dihydrofuran Chemical compound C1CC=CO1 JKTCBAGSMQIFNL-UHFFFAOYSA-N 0.000 abstract 1
- WFWLQNSHRPWKFK-UHFFFAOYSA-N Tegafur Chemical compound O=C1NC(=O)C(F)=CN1C1OCCC1 WFWLQNSHRPWKFK-UHFFFAOYSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 230000001093 anti-cancer Effects 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- WFWLQNSHRPWKFK-ZCFIWIBFSA-N tegafur Chemical compound O=C1NC(=O)C(F)=CN1[C@@H]1OCCC1 WFWLQNSHRPWKFK-ZCFIWIBFSA-N 0.000 abstract 1
- 229960001674 tegafur Drugs 0.000 abstract 1
- 229940035893 uracil Drugs 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/20—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL50671A IL50671A (en) | 1976-10-12 | 1976-10-12 | Process for the preparation of n1-(2'furanidyl)-5-fluoro-uracil and bis-2'-furanidylether as intermediate therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE7711381L true SE7711381L (sv) | 1978-04-13 |
Family
ID=11049169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7711381A SE7711381L (sv) | 1976-10-12 | 1977-10-10 | Forfarande for framstellning av n1-(2'-furanidyl)-5-fluoruracil |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US4174446A (da) |
| JP (2) | JPS5346960A (da) |
| AT (1) | AT363101B (da) |
| AU (1) | AU508758B2 (da) |
| BE (1) | BE859529A (da) |
| CH (1) | CH637127A5 (da) |
| DE (1) | DE2744956A1 (da) |
| DK (1) | DK143230C (da) |
| ES (1) | ES463072A1 (da) |
| FI (1) | FI63570C (da) |
| FR (1) | FR2367762A1 (da) |
| GB (1) | GB1554393A (da) |
| IL (1) | IL50671A (da) |
| NL (1) | NL7711171A (da) |
| NO (1) | NO146911C (da) |
| NZ (1) | NZ185348A (da) |
| RO (1) | RO72832A (da) |
| SE (1) | SE7711381L (da) |
| YU (1) | YU243177A (da) |
| ZA (1) | ZA776011B (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6135521Y2 (da) * | 1981-01-16 | 1986-10-16 | ||
| JPS57199883A (en) * | 1981-06-03 | 1982-12-07 | Teijin Ltd | Deep color process of fabric |
| JP2009102076A (ja) * | 2009-01-05 | 2009-05-14 | Masayuki Makita | ボトルキャップ |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3912734A (en) * | 1972-11-20 | 1975-10-14 | Solomon Aronovich Giller | Method for preparing N{HD 1{B -(2{40 -furanidyl)-and N{HD 1{B -2(2{40 -pyranidyl) uracils |
-
1976
- 1976-10-12 IL IL50671A patent/IL50671A/xx unknown
-
1977
- 1977-10-05 FI FI772933A patent/FI63570C/fi not_active IP Right Cessation
- 1977-10-05 JP JP12044777A patent/JPS5346960A/ja active Pending
- 1977-10-05 NZ NZ185348A patent/NZ185348A/xx unknown
- 1977-10-05 JP JP12044677A patent/JPS5346987A/ja active Pending
- 1977-10-05 ES ES463072A patent/ES463072A1/es not_active Expired
- 1977-10-06 DE DE19772744956 patent/DE2744956A1/de not_active Withdrawn
- 1977-10-06 GB GB41580/77A patent/GB1554393A/en not_active Expired
- 1977-10-07 ZA ZA00776011A patent/ZA776011B/xx unknown
- 1977-10-10 BE BE181577A patent/BE859529A/xx not_active IP Right Cessation
- 1977-10-10 DK DK449477A patent/DK143230C/da not_active IP Right Cessation
- 1977-10-10 SE SE7711381A patent/SE7711381L/xx not_active Application Discontinuation
- 1977-10-10 YU YU02431/77A patent/YU243177A/xx unknown
- 1977-10-11 NO NO773463A patent/NO146911C/no unknown
- 1977-10-11 RO RO7791810A patent/RO72832A/ro unknown
- 1977-10-11 NL NL7711171A patent/NL7711171A/xx not_active Application Discontinuation
- 1977-10-11 CH CH1239577A patent/CH637127A5/de not_active IP Right Cessation
- 1977-10-11 US US05/841,023 patent/US4174446A/en not_active Expired - Lifetime
- 1977-10-11 AT AT0725277A patent/AT363101B/de not_active IP Right Cessation
- 1977-10-12 FR FR7730685A patent/FR2367762A1/fr active Granted
- 1977-10-12 AU AU29618/77A patent/AU508758B2/en not_active Expired
-
1979
- 1979-04-30 US US06/034,422 patent/US4212814A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FI63570B (fi) | 1983-03-31 |
| FI772933A (fi) | 1978-04-13 |
| GB1554393A (en) | 1979-10-17 |
| AT363101B (de) | 1981-07-10 |
| NO146911B (no) | 1982-09-20 |
| YU243177A (en) | 1983-01-21 |
| DE2744956A1 (de) | 1978-04-13 |
| JPS5346987A (en) | 1978-04-27 |
| ES463072A1 (es) | 1978-11-16 |
| CH637127A5 (de) | 1983-07-15 |
| NZ185348A (en) | 1980-04-28 |
| FR2367762B1 (da) | 1982-03-05 |
| AU508758B2 (en) | 1980-04-03 |
| ATA725277A (de) | 1980-12-15 |
| BE859529A (fr) | 1978-04-10 |
| ZA776011B (en) | 1978-11-29 |
| RO72832A (ro) | 1982-09-09 |
| DK449477A (da) | 1978-04-13 |
| FI63570C (fi) | 1983-07-11 |
| JPS5346960A (en) | 1978-04-27 |
| FR2367762A1 (fr) | 1978-05-12 |
| NO146911C (no) | 1982-12-29 |
| AU2961877A (en) | 1979-04-26 |
| NL7711171A (nl) | 1978-04-14 |
| NO773463L (no) | 1978-04-13 |
| US4212814A (en) | 1980-07-15 |
| DK143230C (da) | 1981-11-30 |
| DK143230B (da) | 1981-07-27 |
| IL50671A (en) | 1980-03-31 |
| IL50671A0 (en) | 1976-12-31 |
| US4174446A (en) | 1979-11-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 7711381-9 |