Patents

Search tools Text Classification Chemistry Measure Numbers Full documents Title Abstract Claims All Any Exact Not Add AND condition These CPCs and their children These exact CPCs Add AND condition
Exact Exact Batch Similar Substructure Substructure (SMARTS) Full documents Claims only Add AND condition
Add AND condition
Application Numbers Publication Numbers Either Add AND condition

AZABYCLOHEXANES, ITS USE AND MANUFACTURE

Abstract

Optically active compounds of the formula: <IMAGE> are prepared by reduction of optically active corresponding compounds of the formula: <IMAGE> in which one R denotes an oxo or hydroxyl group, the other R denotes hydrogen or both Rs denote oxo groups or hydroxyl groups, with a hydride, at -70 to 125 DEG C and in an inert, aprotic solvent, or by resolution of the racemic compounds obtained from the reduction, using an optically active acid. In the formula I, the phenyl radical is unsubstituted or mono- or di-substituted by halogen, straight-chain C1-C6-alkyl, singly branched C1-C5-alkyl, C1-C6-alkoxy, trifluoromethyl, nitro, amino, acetamido and/or hydroxyl, X denotes hydrogen, straight-chain C1-C8-alkyl or a group CnH2nR1 where n = 1 to 3 and R1 = phenyl or p-fluorobenzoyl. The compounds are distinguished by an analgesic action; they can be used therapeutically as analgesics.

Classifications

C07C61/40 Unsaturated compounds containing halogen
View 7 more classifications

Landscapes

Show more

SE7710367L

Sweden

Other languages
Swedish
Inventor
W J Fanshawe
J W Epstein
L S Crawley
C M Hofmann
S R Safir

Worldwide applications
1977 GR AR AU NL DE YU CH BE DK AT PL HU FR SE DD JP 1978 AR 1980 AT DK DK 1982 CH SE YU

Application SE7710367A events