SE7503356L - - Google Patents
Info
- Publication number
- SE7503356L SE7503356L SE7503356A SE7503356A SE7503356L SE 7503356 L SE7503356 L SE 7503356L SE 7503356 A SE7503356 A SE 7503356A SE 7503356 A SE7503356 A SE 7503356A SE 7503356 L SE7503356 L SE 7503356L
- Authority
- SE
- Sweden
- Prior art keywords
- halo
- ethers
- alpha
- methyl
- produced
- Prior art date
Links
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000003246 corticosteroid Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
- C07J7/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16
- C07J7/0055—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT6163774 | 1974-03-27 | ||
| PT6163674 | 1974-03-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7503356L true SE7503356L (xx) | 1975-09-29 |
| SE418294B SE418294B (sv) | 1981-05-18 |
Family
ID=26653426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7503356A SE418294B (sv) | 1974-03-27 | 1975-03-24 | Sett att framstella en 16alfa- eller 16beta-9alfa-klor eller -fluorsteroidester |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4024131A (xx) |
| JP (2) | JPS6043358B2 (xx) |
| AU (1) | AU500060B2 (xx) |
| CA (1) | CA1065848A (xx) |
| DE (1) | DE2512915A1 (xx) |
| HK (2) | HK64779A (xx) |
| NL (1) | NL184321C (xx) |
| PH (1) | PH13537A (xx) |
| SE (1) | SE418294B (xx) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4201778A (en) * | 1977-11-08 | 1980-05-06 | Schering Corporation | 6-Acyloxy-1,4,6-pregnatrienes, their use as anti-inflammatory agents, methods for their manufacture, and 6-oxo-1,4-pregnadiene intermediates |
| DE3069074D1 (en) * | 1979-11-16 | 1984-10-04 | Sterosynt Ltd | 6-alpha-9-alpha-difluoro-16-beta-methyl-prednisolone-17,21 diesters and pharmaceutical compositions containing them |
| PT71309A (en) * | 1980-05-27 | 1980-06-01 | Hovione Sociedade Quimica Lda | Process of selective |
| IL66432A0 (en) * | 1981-08-04 | 1982-12-31 | Plurichemie Anstalt | Process for the preparation of steroidal esters |
| PT78973A (en) * | 1984-07-25 | 1984-08-01 | Joao Emerico Villax | New preparation process of the 9alpha-fluoro 17,21-acylates or hidroxilades in 17 and 21 chloro-corticosteroid |
| JPS62111184U (xx) * | 1985-12-29 | 1987-07-15 | ||
| JPH07116215B2 (ja) * | 1989-04-19 | 1995-12-13 | エスエス製薬株式会社 | 新規なステロイド化合物 |
| ES2305029T3 (es) * | 2000-12-22 | 2008-11-01 | Nippon Shinyaku Co., Ltd. | Agente preventivo/terapeutico para enfermedades inflamatorias del tracto respiratorio. |
| CN104558082B (zh) * | 2013-10-16 | 2018-01-23 | 天津金耀集团有限公司 | 一种倍氯米松双丙酸酯的合成方法 |
| CN104558083B (zh) * | 2013-10-16 | 2018-08-31 | 天津金耀集团有限公司 | 一种倍氯米松双丙酸酯无有机溶剂的合成方法 |
| CN111944002A (zh) * | 2020-07-29 | 2020-11-17 | 河南利华制药有限公司 | 一种倍氯米松二丙酸酯中间体及制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1047518A (en) * | 1963-06-11 | 1966-11-02 | Glaxo Lab Ltd | 17ª-monoesters of 11,17,21-trihydroxy steroid compounds |
| GB1070751A (en) * | 1964-01-28 | 1967-06-01 | Glaxo Lab Ltd | 17-esters of 17-hydroxy-21-desoxy-steroids |
| NL6612191A (xx) * | 1965-08-30 | 1967-03-01 | ||
| US3639434A (en) * | 1967-02-02 | 1972-02-01 | Boots Pure Drug Co Ltd | 17-acyloxysteroids and their manufacture |
| CH510655A (de) * | 1967-11-17 | 1971-07-31 | Ciba Geigy Ag | Verfahren zur Herstellung neuer Halogenpregnadiene |
| GB1227992A (xx) * | 1968-01-23 | 1971-04-15 | Koninklijke Gist Spiritus | |
| GB1281689A (en) * | 1968-10-14 | 1972-07-12 | Glaxo Lab Ltd | Steroid 21-phosphates |
| BE785812A (fr) * | 1971-07-05 | 1973-01-04 | Glaxo Lab Ltd | Nouveaux composes steroides |
-
1975
- 1975-03-24 SE SE7503356A patent/SE418294B/xx not_active IP Right Cessation
- 1975-03-24 DE DE19752512915 patent/DE2512915A1/de active Granted
- 1975-03-25 US US05/561,948 patent/US4024131A/en not_active Expired - Lifetime
- 1975-03-25 PH PH16967A patent/PH13537A/en unknown
- 1975-03-26 JP JP50036524A patent/JPS6043358B2/ja not_active Expired
- 1975-03-26 CA CA223,091A patent/CA1065848A/en not_active Expired
- 1975-03-27 AU AU79603/75A patent/AU500060B2/en not_active Expired
- 1975-03-27 NL NLAANVRAGE7503788,A patent/NL184321C/xx not_active IP Right Cessation
-
1979
- 1979-09-13 HK HK647/79A patent/HK64779A/xx unknown
- 1979-09-13 HK HK646/79A patent/HK64679A/xx unknown
-
1983
- 1983-04-21 JP JP58069325A patent/JPS58189200A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6241680B2 (xx) | 1987-09-03 |
| JPS58189200A (ja) | 1983-11-04 |
| JPS6043358B2 (ja) | 1985-09-27 |
| DE2512915C2 (xx) | 1987-09-10 |
| PH13537A (en) | 1980-06-19 |
| AU7960375A (en) | 1976-09-30 |
| AU500060B2 (en) | 1979-05-10 |
| CA1065848A (en) | 1979-11-06 |
| NL184321C (nl) | 1989-06-16 |
| DE2512915A1 (de) | 1975-10-09 |
| HK64779A (en) | 1979-09-21 |
| US4024131A (en) | 1977-05-17 |
| SE418294B (sv) | 1981-05-18 |
| NL184321B (nl) | 1989-01-16 |
| NL7503788A (nl) | 1975-09-30 |
| JPS50157353A (xx) | 1975-12-19 |
| HK64679A (en) | 1979-09-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAL | Patent in force |
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| NUG | Patent has lapsed |
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