SE7409535L - - Google Patents

Info

Publication number
SE7409535L
SE7409535L SE7409535A SE7409535A SE7409535L SE 7409535 L SE7409535 L SE 7409535L SE 7409535 A SE7409535 A SE 7409535A SE 7409535 A SE7409535 A SE 7409535A SE 7409535 L SE7409535 L SE 7409535L
Authority
SE
Sweden
Prior art keywords
amino
benzylamine
reaction
new process
proparation
Prior art date
Application number
SE7409535A
Other languages
Unknown language ( )
Other versions
SE418178B (en
Inventor
J Keck
G Kruger
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19732337334 external-priority patent/DE2337334A1/en
Priority claimed from DE19732337363 external-priority patent/DE2337363A1/en
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of SE7409535L publication Critical patent/SE7409535L/
Publication of SE418178B publication Critical patent/SE418178B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

2-amino-benzylamine The invention relates to a new process for the preparation of 2-amino-benzylamine derivatives having valuable pharmacological properties, in particular a secretolytic and/or antitussive activity. The process comprises the reaction of the corresponding 2-amino-benzyl alcohol with an appropriate amine, either the amino group being acylated or the reaction being performed in the presence of an organic acid. Examples of the proparation of certain 2-amino-benzylamine by means of the new process are given.
SE7409535A 1973-07-23 1974-07-22 NEW PROCEDURE FOR PREPARING 2-AMINO-BENZYLAMINES SE418178B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19732337334 DE2337334A1 (en) 1973-07-23 1973-07-23 Anti-tussive secretolytic 2-aminobenzylamines prepn. - by reaction of 2-acylaminobenzyl alcohols and amines
DE19732337363 DE2337363A1 (en) 1973-07-23 1973-07-23 Anti-tussive secretolytic 2-aminobenzylamines prepn. - by reaction of 2-acylaminobenzyl alcohols and amines

Publications (2)

Publication Number Publication Date
SE7409535L true SE7409535L (en) 1975-01-24
SE418178B SE418178B (en) 1981-05-11

Family

ID=25765536

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7409535A SE418178B (en) 1973-07-23 1974-07-22 NEW PROCEDURE FOR PREPARING 2-AMINO-BENZYLAMINES

Country Status (13)

Country Link
JP (1) JPS57303B2 (en)
AT (1) AT331779B (en)
CA (1) CA1052790A (en)
CH (2) CH605614A5 (en)
DK (1) DK137952C (en)
ES (1) ES427622A1 (en)
FI (1) FI61700C (en)
HU (1) HU168702B (en)
NL (1) NL7409043A (en)
NO (1) NO139085C (en)
PL (1) PL91508B1 (en)
SE (1) SE418178B (en)
YU (1) YU36917B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ2017775A3 (en) * 2017-12-04 2019-08-21 Vysoká Škola Báňská-Technická Univerzita Ostrava Device for reducing the abrasive effects of flowing bulk material

Also Published As

Publication number Publication date
HU168702B (en) 1976-06-28
YU36917B (en) 1984-08-31
YU170574A (en) 1982-06-18
JPS57303B2 (en) 1982-01-06
JPS5047946A (en) 1975-04-28
FI61700C (en) 1982-09-10
PL91508B1 (en) 1977-02-28
FI61700B (en) 1982-05-31
ATA510374A (en) 1975-12-15
DK137952C (en) 1978-11-06
ES427622A1 (en) 1976-08-01
NO139085C (en) 1979-01-03
DK394674A (en) 1975-03-10
NL7409043A (en) 1975-01-27
DK137952B (en) 1978-06-12
CH620668A5 (en) 1980-12-15
NO139085B (en) 1978-09-25
NO742674L (en) 1975-02-17
AT331779B (en) 1976-08-25
FI177374A (en) 1975-01-24
SE418178B (en) 1981-05-11
CA1052790A (en) 1979-04-17
CH605614A5 (en) 1978-09-29

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