SE500044C2 - Peptidförening, antiserum framställt med användning av denna förening samt användning av föreningen - Google Patents
Peptidförening, antiserum framställt med användning av denna förening samt användning av föreningenInfo
- Publication number
- SE500044C2 SE500044C2 SE8500712A SE8500712A SE500044C2 SE 500044 C2 SE500044 C2 SE 500044C2 SE 8500712 A SE8500712 A SE 8500712A SE 8500712 A SE8500712 A SE 8500712A SE 500044 C2 SE500044 C2 SE 500044C2
- Authority
- SE
- Sweden
- Prior art keywords
- protein
- amyloid
- compound
- peptide compound
- amino acid
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims abstract description 26
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 26
- 125000000539 amino acid group Chemical group 0.000 claims abstract description 12
- 102000054727 Serum Amyloid A Human genes 0.000 claims abstract 12
- 108700028909 Serum Amyloid A Proteins 0.000 claims abstract 6
- 101710190759 Serum amyloid A protein Proteins 0.000 claims abstract 6
- 210000004369 blood Anatomy 0.000 claims description 4
- 239000008280 blood Substances 0.000 claims description 4
- 238000001514 detection method Methods 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 abstract description 3
- 150000001413 amino acids Chemical group 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 description 2
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 239000004475 Arginine Substances 0.000 description 1
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 description 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 description 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 description 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 description 1
- 235000004279 alanine Nutrition 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 1
- 235000009582 asparagine Nutrition 0.000 description 1
- 229960001230 asparagine Drugs 0.000 description 1
- 235000003704 aspartic acid Nutrition 0.000 description 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 235000013922 glutamic acid Nutrition 0.000 description 1
- 239000004220 glutamic acid Substances 0.000 description 1
- 125000000291 glutamic acid group Chemical group N[C@@H](CCC(O)=O)C(=O)* 0.000 description 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- 238000002649 immunization Methods 0.000 description 1
- 238000003119 immunoblot Methods 0.000 description 1
- 230000002055 immunohistochemical effect Effects 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 229960000310 isoleucine Drugs 0.000 description 1
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 description 1
- 125000000741 isoleucyl group Chemical group [H]N([H])C(C(C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=O)O* 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 125000003607 serino group Chemical group [H]N([H])[C@]([H])(C(=O)[*])C(O[H])([H])[H] 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Rheumatology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Rehabilitation Therapy (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8500712A SE500044C2 (sv) | 1985-02-15 | 1985-02-15 | Peptidförening, antiserum framställt med användning av denna förening samt användning av föreningen |
| AT86101063T ATE74367T1 (de) | 1985-02-15 | 1986-01-27 | Peptidverbindung und durch diese verbindung hergestelltes antiserum. |
| EP86101063A EP0191349B1 (de) | 1985-02-15 | 1986-01-27 | Peptidverbindung und durch diese Verbindung hergestelltes Antiserum |
| DE8686101063T DE3684625D1 (de) | 1985-02-15 | 1986-01-27 | Peptidverbindung und durch diese verbindung hergestelltes antiserum. |
| US06/826,551 US4755380A (en) | 1985-02-15 | 1986-02-06 | Peptide from amyloid A and antiserum therefor |
| JP61029162A JPS61191697A (ja) | 1985-02-15 | 1986-02-14 | ペプチド化合物およびこの化合物を使用して製造された抗血清 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8500712A SE500044C2 (sv) | 1985-02-15 | 1985-02-15 | Peptidförening, antiserum framställt med användning av denna förening samt användning av föreningen |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE8500712D0 SE8500712D0 (sv) | 1985-02-15 |
| SE8500712L SE8500712L (sv) | 1986-08-16 |
| SE500044C2 true SE500044C2 (sv) | 1994-03-28 |
Family
ID=20359128
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8500712A SE500044C2 (sv) | 1985-02-15 | 1985-02-15 | Peptidförening, antiserum framställt med användning av denna förening samt användning av föreningen |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4755380A (de) |
| EP (1) | EP0191349B1 (de) |
| JP (1) | JPS61191697A (de) |
| AT (1) | ATE74367T1 (de) |
| DE (1) | DE3684625D1 (de) |
| SE (1) | SE500044C2 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE454299B (sv) * | 1986-10-08 | 1988-04-18 | Westermark P | Sats innehallande polypeptid som finns i pankreasoamyloid och/eller antikroppar riktade mot polypeptiden |
| GB8709871D0 (en) * | 1987-04-27 | 1987-06-03 | Turner R C | Peptides |
| GB8720115D0 (en) * | 1987-08-26 | 1987-09-30 | Cooper G J S | Treatment of diabetes mellitus |
| US5134062A (en) * | 1988-03-22 | 1992-07-28 | Cornell Research Foundation, Inc. | Diagnosis of neuronal disorders and screening potential therapeutic agents therefor |
| AU711163B2 (en) * | 1995-07-21 | 1999-10-07 | Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin, The | Method for the quantitative measurement of human acute phase serum amyloid a protein; recombinant protein; specific antibody |
| WO1997006184A1 (fr) * | 1995-08-08 | 1997-02-20 | Eiken Kagaku Kabushiki Kaisha | Anticorps reconnaissant l'amyloide a serique |
| AU770994B2 (en) | 1999-08-25 | 2004-03-11 | Accuplex, L.L.C. | Diagnostic assays of secreted biological fluids for detection of infection and inflammatory conditions |
| WO2001031006A2 (en) * | 1999-10-22 | 2001-05-03 | The Board Of Regents Of The University Of Nebraska | Serum amyloid a isoform from colostrum |
| AU2002364507A1 (en) * | 2001-11-21 | 2003-06-10 | Board Of Regents Of The University Of Nebraska | Mammary-associated serum amyloid a3 promoter sequences and uses for same |
| US7368546B2 (en) * | 2003-01-21 | 2008-05-06 | The Board Of Regents Of The University Of Nebraska | Human SAA3 nucleic acid molecule, protein, and methods of use for same |
| ATE458201T1 (de) * | 2003-12-23 | 2010-03-15 | Hoffmann La Roche | Methode zur beurteilung von rheumatoider arthritis durch bestimmung von anti-ccp und interleukin 6 |
| BR112012007162A2 (pt) * | 2009-09-30 | 2016-03-29 | Battelle Memorial Institute | poliol de reticulação multifuncional, e, método para produzir um poliol de reticulação multifuncional |
| CN108299551A (zh) * | 2018-02-09 | 2018-07-20 | 北京市华信行生物科技有限公司 | 血清淀粉样蛋白a1突变体及其制备方法和应用 |
-
1985
- 1985-02-15 SE SE8500712A patent/SE500044C2/sv unknown
-
1986
- 1986-01-27 AT AT86101063T patent/ATE74367T1/de not_active IP Right Cessation
- 1986-01-27 DE DE8686101063T patent/DE3684625D1/de not_active Expired - Fee Related
- 1986-01-27 EP EP86101063A patent/EP0191349B1/de not_active Expired - Lifetime
- 1986-02-06 US US06/826,551 patent/US4755380A/en not_active Expired - Fee Related
- 1986-02-14 JP JP61029162A patent/JPS61191697A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPS61191697A (ja) | 1986-08-26 |
| EP0191349A3 (en) | 1988-04-20 |
| DE3684625D1 (de) | 1992-05-07 |
| ATE74367T1 (de) | 1992-04-15 |
| US4755380A (en) | 1988-07-05 |
| EP0191349B1 (de) | 1992-04-01 |
| SE8500712D0 (sv) | 1985-02-15 |
| SE8500712L (sv) | 1986-08-16 |
| EP0191349A2 (de) | 1986-08-20 |
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