SE415978B - Forfarande for framstellning av 7-acylamido-3-cefem-4-karbonsyror - Google Patents

Forfarande for framstellning av 7-acylamido-3-cefem-4-karbonsyror

Info

Publication number
SE415978B
SE415978B SE7217020A SE1702072A SE415978B SE 415978 B SE415978 B SE 415978B SE 7217020 A SE7217020 A SE 7217020A SE 1702072 A SE1702072 A SE 1702072A SE 415978 B SE415978 B SE 415978B
Authority
SE
Sweden
Prior art keywords
cefem
acylamido
preparing
procedure
carbon acids
Prior art date
Application number
SE7217020A
Other languages
English (en)
Swedish (sv)
Inventor
T Ishimaru
Y Kodama
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP220272A external-priority patent/JPS5414114B2/ja
Priority claimed from JP220172A external-priority patent/JPS5317598B2/ja
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of SE415978B publication Critical patent/SE415978B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
SE7217020A 1971-12-28 1972-12-27 Forfarande for framstellning av 7-acylamido-3-cefem-4-karbonsyror SE415978B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP220272A JPS5414114B2 (de) 1971-12-28 1971-12-28
JP220172A JPS5317598B2 (de) 1971-12-28 1971-12-28

Publications (1)

Publication Number Publication Date
SE415978B true SE415978B (sv) 1980-11-17

Family

ID=26335536

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7217020A SE415978B (sv) 1971-12-28 1972-12-27 Forfarande for framstellning av 7-acylamido-3-cefem-4-karbonsyror

Country Status (16)

Country Link
US (1) US3864340A (de)
AR (1) AR207429A1 (de)
AT (1) AT330346B (de)
BE (1) BE793191A (de)
BR (1) BR7209167D0 (de)
CA (1) CA998387A (de)
CH (1) CH566342A5 (de)
DE (1) DE2263861C3 (de)
FR (1) FR2165993B1 (de)
GB (1) GB1379790A (de)
IE (1) IE37195B1 (de)
IL (1) IL40913A (de)
NL (1) NL164038C (de)
NO (1) NO145918C (de)
PH (1) PH10311A (de)
SE (1) SE415978B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1450043A (en) * 1972-09-08 1976-09-22 Beecham Group Ltd Penicillins
JPS5725557B2 (de) * 1972-11-17 1982-05-29
JPS5653557B2 (de) * 1973-10-15 1981-12-19
US3988326A (en) * 1974-02-22 1976-10-26 Meiji Seika Kaisha, Ltd. Process for N-acylation of 7 amino cephem compounds
DE2512284A1 (de) * 1974-03-28 1975-10-09 Fujisawa Pharmaceutical Co Cephalosporansaeurederivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
GB1457238A (en) * 1974-05-28 1976-12-01 Sangyo Kagaku Kenkyu Kyokai Cephalosporin derivatives
US3954745A (en) * 1974-09-12 1976-05-04 Eli Lilly And Company Process for preparing cefazolin
US4020060A (en) * 1975-07-22 1977-04-26 Richardson-Merrell Inc. 7-[α-Amino-ω-(3,4-methylenedioxyphenyl)acylamido]cephalosporanic acid derivatives
US4033956A (en) * 1975-07-22 1977-07-05 Richardson-Merrell Inc. 7[α-Amino-ω-(2,3-methylenedioxy-phenyl)acylamido]cephalosporanic acid derivatives
YU37171B (en) * 1975-12-05 1984-08-31 Krka Novo Mesto Process for preparing 7-(d-2-amino-2-phenylacetamido)-3-methyl-3-cephem-4-carboxylic acid
JPS52142089A (en) * 1976-05-19 1977-11-26 Meiji Seika Kaisha Ltd Preparation of cephalosporanic acid derivatives
IT1193478B (it) * 1979-06-14 1988-07-08 Ausonia Farma Srl Procedimento per la preparazione del 7-(l-amino-l-fenilacetamido)-3-metil-3-cefem-4-carbossilato di pivaloilossimetile
IT1126544B (it) * 1979-12-07 1986-05-21 Dobfar Spa Procedimento per la preparazione di derivati dell'acido 7-amino-desacetossi cefalosporanico
YU44832B (en) * 1981-08-03 1991-04-30 Pliva Pharm & Chem Works Process for preparing semisynthetic cephalosporins
GB8714180D0 (en) * 1987-06-17 1987-07-22 Rifar Srl Anhydrous crystalline cefadroxil
GB9115203D0 (en) * 1991-07-15 1991-08-28 Biochemie Gmbh Improvements in or relating to beta lactam production
US5908929A (en) * 1996-12-05 1999-06-01 Vitara Chemicals Limited Process for the manufacture of the antibiotic 7-(D-α-amino-α-phenylacetamido)-3-methyl-3-cephem-4-carboxylic acid (cephalexin) and pharmaceutically acceptable salts thereof
US6475522B1 (en) 2000-08-30 2002-11-05 Hammond Group, Inc. Synthetic polymer compositions containing antibiotics as antidegradants

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3503967A (en) * 1968-08-26 1970-03-31 Bristol Myers Co Process for the preparation of 7 - (alpha-(4 - pyridylthio)acetamido)cephalosporanic acid
US3769281A (en) * 1970-07-09 1973-10-30 Lilly Co Eli Deblocking process for cephalosporin antibiotics

Also Published As

Publication number Publication date
CA998387A (en) 1976-10-12
PH10311A (en) 1976-11-25
DE2263861A1 (de) 1973-07-05
IE37195B1 (en) 1977-05-25
NL7217650A (de) 1973-07-02
BR7209167D0 (pt) 1973-09-20
IL40913A (en) 1975-07-28
DE2263861B2 (de) 1980-03-06
NL164038B (nl) 1980-06-16
FR2165993A1 (de) 1973-08-10
BE793191A (fr) 1973-06-22
CH566342A5 (de) 1975-09-15
NO145918C (no) 1982-06-23
US3864340A (en) 1975-02-04
ATA1095672A (de) 1975-09-15
NO145918B (no) 1982-03-15
FR2165993B1 (de) 1976-12-03
AR207429A1 (es) 1976-10-08
NL164038C (nl) 1980-11-17
DE2263861C3 (de) 1980-10-23
GB1379790A (en) 1975-01-08
IE37195L (en) 1973-06-28
AT330346B (de) 1976-06-25
IL40913A0 (en) 1973-01-30

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