AT330346B - Verfahren zur herstellung von 7-acylamido -3- cephem-4-carbonsauren - Google Patents

Verfahren zur herstellung von 7-acylamido -3- cephem-4-carbonsauren

Info

Publication number
AT330346B
AT330346B AT1095672A AT1095672A AT330346B AT 330346 B AT330346 B AT 330346B AT 1095672 A AT1095672 A AT 1095672A AT 1095672 A AT1095672 A AT 1095672A AT 330346 B AT330346 B AT 330346B
Authority
AT
Austria
Prior art keywords
acylamido
cephem
production
carbonic acids
carbonic
Prior art date
Application number
AT1095672A
Other languages
English (en)
Other versions
ATA1095672A (de
Inventor
Toshiyasu Ishimaru
Yutaka Kodama
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP220272A external-priority patent/JPS5414114B2/ja
Priority claimed from JP220172A external-priority patent/JPS5317598B2/ja
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of ATA1095672A publication Critical patent/ATA1095672A/de
Application granted granted Critical
Publication of AT330346B publication Critical patent/AT330346B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/227-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
AT1095672A 1971-12-28 1972-12-21 Verfahren zur herstellung von 7-acylamido -3- cephem-4-carbonsauren AT330346B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP220272A JPS5414114B2 (de) 1971-12-28 1971-12-28
JP220172A JPS5317598B2 (de) 1971-12-28 1971-12-28

Publications (2)

Publication Number Publication Date
ATA1095672A ATA1095672A (de) 1975-09-15
AT330346B true AT330346B (de) 1976-06-25

Family

ID=26335536

Family Applications (1)

Application Number Title Priority Date Filing Date
AT1095672A AT330346B (de) 1971-12-28 1972-12-21 Verfahren zur herstellung von 7-acylamido -3- cephem-4-carbonsauren

Country Status (16)

Country Link
US (1) US3864340A (de)
AR (1) AR207429A1 (de)
AT (1) AT330346B (de)
BE (1) BE793191A (de)
BR (1) BR7209167D0 (de)
CA (1) CA998387A (de)
CH (1) CH566342A5 (de)
DE (1) DE2263861C3 (de)
FR (1) FR2165993B1 (de)
GB (1) GB1379790A (de)
IE (1) IE37195B1 (de)
IL (1) IL40913A (de)
NL (1) NL164038C (de)
NO (1) NO145918C (de)
PH (1) PH10311A (de)
SE (1) SE415978B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1450043A (en) * 1972-09-08 1976-09-22 Beecham Group Ltd Penicillins
JPS5725557B2 (de) * 1972-11-17 1982-05-29
JPS5653557B2 (de) * 1973-10-15 1981-12-19
US3988326A (en) * 1974-02-22 1976-10-26 Meiji Seika Kaisha, Ltd. Process for N-acylation of 7 amino cephem compounds
DE2512284A1 (de) * 1974-03-28 1975-10-09 Fujisawa Pharmaceutical Co Cephalosporansaeurederivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
GB1457238A (en) * 1974-05-28 1976-12-01 Sangyo Kagaku Kenkyu Kyokai Cephalosporin derivatives
US3954745A (en) * 1974-09-12 1976-05-04 Eli Lilly And Company Process for preparing cefazolin
US4033956A (en) * 1975-07-22 1977-07-05 Richardson-Merrell Inc. 7[α-Amino-ω-(2,3-methylenedioxy-phenyl)acylamido]cephalosporanic acid derivatives
US4020060A (en) * 1975-07-22 1977-04-26 Richardson-Merrell Inc. 7-[α-Amino-ω-(3,4-methylenedioxyphenyl)acylamido]cephalosporanic acid derivatives
YU37171B (en) * 1975-12-05 1984-08-31 Krka Novo Mesto Process for preparing 7-(d-2-amino-2-phenylacetamido)-3-methyl-3-cephem-4-carboxylic acid
JPS52142089A (en) * 1976-05-19 1977-11-26 Meiji Seika Kaisha Ltd Preparation of cephalosporanic acid derivatives
IT1193478B (it) * 1979-06-14 1988-07-08 Ausonia Farma Srl Procedimento per la preparazione del 7-(l-amino-l-fenilacetamido)-3-metil-3-cefem-4-carbossilato di pivaloilossimetile
IT1126544B (it) * 1979-12-07 1986-05-21 Dobfar Spa Procedimento per la preparazione di derivati dell'acido 7-amino-desacetossi cefalosporanico
YU44832B (en) * 1981-08-03 1991-04-30 Pliva Pharm & Chem Works Process for preparing semisynthetic cephalosporins
GB8714180D0 (en) * 1987-06-17 1987-07-22 Rifar Srl Anhydrous crystalline cefadroxil
GB9115203D0 (en) * 1991-07-15 1991-08-28 Biochemie Gmbh Improvements in or relating to beta lactam production
US5908929A (en) * 1996-12-05 1999-06-01 Vitara Chemicals Limited Process for the manufacture of the antibiotic 7-(D-α-amino-α-phenylacetamido)-3-methyl-3-cephem-4-carboxylic acid (cephalexin) and pharmaceutically acceptable salts thereof
US6475522B1 (en) * 2000-08-30 2002-11-05 Hammond Group, Inc. Synthetic polymer compositions containing antibiotics as antidegradants

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3503967A (en) * 1968-08-26 1970-03-31 Bristol Myers Co Process for the preparation of 7 - (alpha-(4 - pyridylthio)acetamido)cephalosporanic acid
US3769281A (en) * 1970-07-09 1973-10-30 Lilly Co Eli Deblocking process for cephalosporin antibiotics

Also Published As

Publication number Publication date
DE2263861A1 (de) 1973-07-05
NO145918B (no) 1982-03-15
BE793191A (fr) 1973-06-22
IE37195B1 (en) 1977-05-25
AR207429A1 (es) 1976-10-08
FR2165993B1 (de) 1976-12-03
DE2263861B2 (de) 1980-03-06
NL164038C (nl) 1980-11-17
NL7217650A (de) 1973-07-02
FR2165993A1 (de) 1973-08-10
NO145918C (no) 1982-06-23
ATA1095672A (de) 1975-09-15
PH10311A (en) 1976-11-25
NL164038B (nl) 1980-06-16
IL40913A (en) 1975-07-28
IE37195L (en) 1973-06-28
IL40913A0 (en) 1973-01-30
GB1379790A (en) 1975-01-08
US3864340A (en) 1975-02-04
CA998387A (en) 1976-10-12
BR7209167D0 (pt) 1973-09-20
CH566342A5 (de) 1975-09-15
DE2263861C3 (de) 1980-10-23
SE415978B (sv) 1980-11-17

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Legal Events

Date Code Title Description
ELA Expired due to lapse of time