SE411213B - Sett att framstella i 21-stellning monoalkylerade steroider ur pregnanserien - Google Patents

Sett att framstella i 21-stellning monoalkylerade steroider ur pregnanserien

Info

Publication number
SE411213B
SE411213B SE7300347A SE7300347A SE411213B SE 411213 B SE411213 B SE 411213B SE 7300347 A SE7300347 A SE 7300347A SE 7300347 A SE7300347 A SE 7300347A SE 411213 B SE411213 B SE 411213B
Authority
SE
Sweden
Prior art keywords
monoalkylated
steroids
manufacture
way
pregnancy
Prior art date
Application number
SE7300347A
Other languages
English (en)
Swedish (sv)
Inventor
G F Woods
J Cairns
G Mcgarry
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of SE411213B publication Critical patent/SE411213B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16
    • C07J7/0055—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7300347A 1972-01-12 1973-01-11 Sett att framstella i 21-stellning monoalkylerade steroider ur pregnanserien SE411213B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB153472A GB1416427A (en) 1972-01-12 1972-01-12 Alkylated pregnanes and process for obtaining same

Publications (1)

Publication Number Publication Date
SE411213B true SE411213B (sv) 1979-12-10

Family

ID=9723658

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7300347A SE411213B (sv) 1972-01-12 1973-01-11 Sett att framstella i 21-stellning monoalkylerade steroider ur pregnanserien

Country Status (17)

Country Link
US (1) US3862194A (fr)
JP (1) JPS5614678B2 (fr)
AT (1) AT367068B (fr)
BE (1) BE793958A (fr)
CA (1) CA1022158A (fr)
CH (1) CH615934A5 (fr)
DE (1) DE2301317C2 (fr)
DK (1) DK139031B (fr)
FI (1) FI52587C (fr)
FR (1) FR2168006B1 (fr)
GB (1) GB1416427A (fr)
HU (1) HU167205B (fr)
IE (1) IE37048B1 (fr)
IL (1) IL41160A (fr)
NL (2) NL179287C (fr)
PH (1) PH9719A (fr)
SE (1) SE411213B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947478A (en) * 1972-01-12 1976-03-30 Akzona Incorporated Alkylated 3,20-diketo-Δ4 -steroids of the pregnane series
GB1436324A (en) * 1972-05-12 1976-05-19 Glaxo Lab Ltd Anaesthetic 3alpha-hydroxy pregnanes
US4031075A (en) * 1973-07-11 1977-06-21 Akzona Incorporated Alkylated pregnanes and process for obtaining same
GB1478968A (en) * 1973-07-11 1977-07-06 Akzo Nv Alkylated pregnanes
JPS5264666A (en) * 1975-11-25 1977-05-28 Sharp Kk Bothhside circuit substrate
DE3064460D1 (en) * 1979-01-24 1983-09-08 Akzo Nv Novel alkylated pregnanes, processes for their preparation and pharmaceutical compositions containing same
JPS58194A (ja) * 1981-06-25 1983-01-05 北陸電気工業株式会社 Ｃｕ粉末導電塗料を用いた印刷抵抗回路基板の製造方法
US4686214A (en) * 1985-10-30 1987-08-11 Alcon Laboratories, Inc. Anti-inflammatory compounds for ophthalmic use
AU7556291A (en) * 1990-03-27 1991-10-21 Schering Corporation Process for 9alpha-hydroxy steroid dehydration
AU1331097A (en) * 1995-12-20 1997-07-14 Schering Corporation Process for preparation of 9,11beta-epoxide steroids
US6040468A (en) * 1996-10-25 2000-03-21 Alcon Laboratories, Inc. Method of preparing 16α, 17α-dialkylated steroids
JP2000502370A (ja) * 1996-10-25 2000-02-29 アルコン ラボラトリーズ，インコーポレイテッド ２１―アルキル化プレグナ−１，４，１６―トリエン―３，２０―ジオンを調製する方法
CN1336824A (zh) * 1997-06-04 2002-02-20 阿克佐诺贝尔公司 抗炎甾类化合物在治疗慢性感染性肠道疾病中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3064017A (en) * 1962-11-13 Preparation viii
US3047594A (en) * 1960-05-11 1962-07-31 Pfizer & Co C Preparation of 21-methyl steroids and intermediates
US3114750A (en) * 1960-11-07 1963-12-17 British Drug Houses Ltd 3-enol ethers of 6-formyl-3-oxo-delta4-steroids and process for their preparation
US3166551A (en) * 1962-01-02 1965-01-19 British Drug Houses Ltd Process for the preparation of 3-oxo-delta4-6-methyl steroids
DE1167829B (de) * 1962-08-03 1964-04-16 Schering Ag Verfahren zur Herstellung von 21-Methyl-í¸-pregnen-11ª‰, 17ª‡-diol-3, 20-dion
US3594407A (en) * 1969-04-03 1971-07-20 American Home Prod 13,17-dialkyl-19-norpregn-4-ene,3,20-diones

Also Published As

Publication number Publication date
IL41160A0 (en) 1973-02-28
ATA28373A (de) 1981-10-15
IE37048B1 (en) 1977-04-27
CA1022158A (en) 1977-12-06
FR2168006B1 (fr) 1976-09-03
IE37048L (en) 1973-07-12
FI52587B (fr) 1977-06-30
NL179287B (nl) 1986-03-17
GB1416427A (en) 1975-12-03
NL930031I1 (nl) 1993-07-01
JPS504060A (fr) 1975-01-16
IL41160A (en) 1977-04-29
CH615934A5 (fr) 1980-02-29
NL7300313A (fr) 1973-07-16
DE2301317C2 (de) 1983-11-03
FI52587C (fi) 1977-10-10
NL179287C (nl) 1986-08-18
BE793958A (fr) 1973-07-12
PH9719A (en) 1976-02-27
DK139031C (fr) 1979-05-14
DK139031B (da) 1978-12-04
HU167205B (fr) 1975-09-27
US3862194A (en) 1975-01-21
FR2168006A1 (fr) 1973-08-24
JPS5614678B2 (fr) 1981-04-06
DE2301317A1 (de) 1973-07-26
AT367068B (de) 1982-05-25

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Legal Events

Date Code Title Description
SPCF Application for supplementary protection certificate filed

Free format text: 7300347

SPCG Supplementary protection certificate granted

Free format text: 7300347, EXPIRES: 19990925