SE406010B - Forfarande och medel for bestemning av beta-laktamasaktivitet - Google Patents
Forfarande och medel for bestemning av beta-laktamasaktivitetInfo
- Publication number
- SE406010B SE406010B SE7212963A SE1296372A SE406010B SE 406010 B SE406010 B SE 406010B SE 7212963 A SE7212963 A SE 7212963A SE 1296372 A SE1296372 A SE 1296372A SE 406010 B SE406010 B SE 406010B
- Authority
- SE
- Sweden
- Prior art keywords
- solution
- process according
- water
- formula
- isomer
- Prior art date
Links
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- 239000006071 cream Substances 0.000 description 1
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- 235000018417 cysteine Nutrition 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 125000002228 disulfide group Chemical group 0.000 description 1
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- 210000000969 egg white Anatomy 0.000 description 1
- 125000006575 electron-withdrawing group Chemical group 0.000 description 1
- 238000001962 electrophoresis Methods 0.000 description 1
- DNJIEGIFACGWOD-UHFFFAOYSA-N ethyl mercaptane Natural products CCS DNJIEGIFACGWOD-UHFFFAOYSA-N 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
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- 238000009472 formulation Methods 0.000 description 1
- 238000007429 general method Methods 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 229960003180 glutathione Drugs 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 238000005470 impregnation Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000004922 lacquer Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 description 1
- 230000002906 microbiologic effect Effects 0.000 description 1
- 229910000403 monosodium phosphate Inorganic materials 0.000 description 1
- 235000019799 monosodium phosphate Nutrition 0.000 description 1
- NSNPSJGHTQIXDO-UHFFFAOYSA-N naphthalene-1-carbonyl chloride Chemical compound C1=CC=C2C(C(=O)Cl)=CC=CC2=C1 NSNPSJGHTQIXDO-UHFFFAOYSA-N 0.000 description 1
- 239000011368 organic material Substances 0.000 description 1
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- 238000010979 pH adjustment Methods 0.000 description 1
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- 230000007170 pathology Effects 0.000 description 1
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N phenylbenzene Natural products C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- UHZYTMXLRWXGPK-UHFFFAOYSA-N phosphorus pentachloride Chemical compound ClP(Cl)(Cl)(Cl)Cl UHZYTMXLRWXGPK-UHFFFAOYSA-N 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000010453 quartz Substances 0.000 description 1
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- 238000007142 ring opening reaction Methods 0.000 description 1
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- 210000002966 serum Anatomy 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 150000003385 sodium Chemical class 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- 235000009518 sodium iodide Nutrition 0.000 description 1
- AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 description 1
- 229940001474 sodium thiosulfate Drugs 0.000 description 1
- 235000019345 sodium thiosulphate Nutrition 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/978—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- G01N2333/986—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides (3.5.2), e.g. beta-lactamase (penicillinase, 3.5.2.6), creatinine amidohydrolase (creatininase, EC 3.5.2.10), N-methylhydantoinase (3.5.2.6)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2415/00—Assays, e.g. immunoassays or enzyme assays, involving penicillins or cephalosporins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/805—Test papers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Cephalosporin Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4679871A GB1408391A (en) | 1971-10-07 | 1971-10-07 | Cephalosporin compounds as reagents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE406010B true SE406010B (sv) | 1979-01-15 |
Family
ID=10442642
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7212963A SE406010B (sv) | 1971-10-07 | 1972-10-06 | Forfarande och medel for bestemning av beta-laktamasaktivitet |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3830700A (da) |
| JP (1) | JPS5618197B2 (da) |
| BE (1) | BE789817A (da) |
| CH (1) | CH609458A5 (da) |
| DE (1) | DE2249165C2 (da) |
| DK (1) | DK143657C (da) |
| FR (1) | FR2155655A5 (da) |
| GB (1) | GB1408391A (da) |
| IE (1) | IE36744B1 (da) |
| NL (1) | NL182896C (da) |
| SE (1) | SE406010B (da) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4144393A (en) * | 1973-12-21 | 1979-03-13 | Glaxo Laboratories Limited | 3-Acetoxymethyl cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyiminoarylacetamido group |
| US4049806A (en) * | 1975-08-15 | 1977-09-20 | Syntex (U.S.A.) Inc. | Cephalosporin type antibacterials |
| US3983113A (en) * | 1975-08-15 | 1976-09-28 | Syntex (U.S.A.) Inc. | Cephalosporin type antibacterials |
| US4112087A (en) * | 1976-11-04 | 1978-09-05 | Syntex (U.S.A.) Inc. | Cephalosporin type antibacterials having a substituted propenyl group in the 3-position |
| US4234683A (en) * | 1978-11-24 | 1980-11-18 | Mcmillan William A | Beta-lactamase diagnostic product and method |
| DE2916433A1 (de) * | 1979-04-24 | 1980-11-13 | Hoechst Ag | Chromophore cephalosporine und verfahren zu ihrer herstellung |
| ZA806977B (en) * | 1979-11-19 | 1981-10-28 | Fujisawa Pharmaceutical Co | 7-acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof |
| DE3006889A1 (de) * | 1980-02-23 | 1981-09-10 | Hoechst Ag, 6000 Frankfurt | Chromogene cephalosporine und verfahren zu ihrer herstellung |
| IL59723A (en) * | 1980-03-27 | 1983-05-15 | Teva Pharma | Determination of antibacterial agents |
| DE3019451A1 (de) * | 1980-05-21 | 1981-11-26 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und reagens zur bestimmung von (beta) -lactamasen |
| JPS58500150A (ja) * | 1981-03-03 | 1983-02-03 | ナシヨナル リサ−チ デイベロツプメント コ−ポレイシヨン | β−ラクタマ−ゼ類同定法およびキツト |
| US4713328A (en) * | 1981-09-30 | 1987-12-15 | Yolken Robert H | Microbial Enzyme assays |
| GB2128737B (en) * | 1982-10-07 | 1986-02-05 | Beecham Group Plc | Antibiotic susceptibility test material |
| US4520022A (en) * | 1983-01-28 | 1985-05-28 | Bristol-Myers Company | Substituted vinyl cephalosporins |
| ZM884A1 (en) * | 1983-01-28 | 1984-10-22 | Bristol Myers Co | Substituted vinyl cephalosporins |
| US4558123A (en) * | 1983-07-22 | 1985-12-10 | Eli Lilly And Company | 3-Exomethylene cephalosporins |
| US4568637A (en) * | 1983-08-10 | 1986-02-04 | Whittaker M.A. Bioproducts, Inc. | Method of determining antibiotics in biological liquids |
| FR2570702B1 (fr) * | 1984-09-27 | 1987-01-09 | Sanofi Sa | Derives des cephalosporines, procedes d'obtention et leur application a titre d'antibiotiques |
| US4764462A (en) * | 1985-08-23 | 1988-08-16 | Georgetown University | Detectably labeled cephalosporin assay for beta-lactamase |
| US5338843A (en) * | 1992-01-30 | 1994-08-16 | Becton, Dickinson And Company | Fluorogenic and chromogenic β-lactamase substrates |
| JP4475868B2 (ja) | 2000-09-22 | 2010-06-09 | 全薬工業株式会社 | セフェム化合物及びそれを含有するｅｓｂｌ検出試薬 |
| JP2004166694A (ja) * | 2002-10-29 | 2004-06-17 | Showa Yakuhin Kako Kk | β−ラクタマーゼ検出試薬組成物、検出キット及び検出方法 |
| ES2324031T3 (es) * | 2002-10-29 | 2009-07-29 | Showa Yakuhin Kako Co., Ltd | Composicion de reactivos para discriminar beta-lactamasas, kit y metodo asociados. |
| FR2881755B1 (fr) * | 2005-02-10 | 2012-11-30 | Biomerieux Sa | Milieux pour la detection specifique de micro-organismes resistants |
| US10782291B2 (en) * | 2006-12-19 | 2020-09-22 | Becton Dickinson And Company | Chromogenic medium for the detection and identification of Vancomycin resistant enterococci and method therefor |
| CA2702257C (en) | 2007-10-09 | 2016-07-12 | Sopharmia, Inc. | Broad spectrum beta-lactamase inhibitors |
| ES2700575T3 (es) | 2013-03-12 | 2019-02-18 | Gladius Pharmaceuticals Corp | 3-Estiril-cefalosporinas derivadas |
| CN106083894B (zh) * | 2016-06-14 | 2018-11-13 | 大连理工大学 | 头孢硝噻吩的合成方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3769277A (en) * | 1970-01-23 | 1973-10-30 | Glaxo Lab Ltd | Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group |
-
0
- BE BE789817D patent/BE789817A/xx not_active IP Right Cessation
-
1971
- 1971-10-07 GB GB4679871A patent/GB1408391A/en not_active Expired
-
1972
- 1972-10-03 US US00294649A patent/US3830700A/en not_active Expired - Lifetime
- 1972-10-06 SE SE7212963A patent/SE406010B/sv unknown
- 1972-10-06 JP JP10233272A patent/JPS5618197B2/ja not_active Expired
- 1972-10-06 CH CH1463172A patent/CH609458A5/xx not_active IP Right Cessation
- 1972-10-06 DK DK494072A patent/DK143657C/da not_active IP Right Cessation
- 1972-10-06 NL NLAANVRAGE7213595,A patent/NL182896C/xx not_active IP Right Cessation
- 1972-10-06 FR FR7235572A patent/FR2155655A5/fr not_active Expired
- 1972-10-06 IE IE1359/72A patent/IE36744B1/xx unknown
- 1972-10-06 DE DE2249165A patent/DE2249165C2/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5618197B2 (da) | 1981-04-27 |
| DK143657C (da) | 1982-03-01 |
| DK143657B (da) | 1981-09-21 |
| US3830700A (en) | 1974-08-20 |
| IE36744L (en) | 1973-04-07 |
| IE36744B1 (en) | 1977-02-16 |
| JPS4850787A (da) | 1973-07-17 |
| GB1408391A (en) | 1975-10-01 |
| BE789817A (fr) | 1973-04-06 |
| CH609458A5 (da) | 1979-02-28 |
| DE2249165C2 (de) | 1983-11-17 |
| FR2155655A5 (da) | 1973-05-18 |
| NL182896C (nl) | 1988-06-01 |
| NL182896B (nl) | 1988-01-04 |
| DE2249165A1 (de) | 1973-04-26 |
| NL7213595A (da) | 1973-04-10 |
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