SE403910B - Mellanprodukter for framstellning av hormonalt verksamma 19-nor-steroider och 9beta,10alfa-steroider - Google Patents

Mellanprodukter for framstellning av hormonalt verksamma 19-nor-steroider och 9beta,10alfa-steroider

Info

Publication number
SE403910B
SE403910B SE7212975A SE1297572A SE403910B SE 403910 B SE403910 B SE 403910B SE 7212975 A SE7212975 A SE 7212975A SE 1297572 A SE1297572 A SE 1297572A SE 403910 B SE403910 B SE 403910B
Authority
SE
Sweden
Prior art keywords
steroids
10alfa
9beta
production
intermediate products
Prior art date
Application number
SE7212975A
Other languages
English (en)
Inventor
Z G Hajos
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US765023A external-priority patent/US3897460A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SE403910B publication Critical patent/SE403910B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/12—Saturated polycyclic compounds
    • C07C61/125—Saturated polycyclic compounds having a carboxyl group bound to a condensed ring system
    • C07C61/13—Saturated polycyclic compounds having a carboxyl group bound to a condensed ring system having two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/18—Saturated compounds containing keto groups
    • C07C62/26—Saturated compounds containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30—Unsaturated compounds
    • C07C62/38—Unsaturated compounds containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7212975A 1968-10-04 1972-02-16 Mellanprodukter for framstellning av hormonalt verksamma 19-nor-steroider och 9beta,10alfa-steroider SE403910B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US765023A US3897460A (en) 1968-10-04 1968-10-04 3{62 -Tertiarybutoxy-decahydro-benz{8 E{9 indenes
US84554669A 1969-07-28 1969-07-28

Publications (1)

Publication Number Publication Date
SE403910B true SE403910B (sv) 1978-09-11

Family

ID=27117546

Family Applications (5)

Application Number Title Priority Date Filing Date
SE7212973A SE385292B (sv) 1968-10-04 1969-10-03 Nya indanonderivat till anvendning som mellanprodukter vid syntes av 19-nor-steroider och 9beta,10alfa-steroider
SE7212972A SE381876B (sv) 1968-10-04 1969-10-03 Forfarande for framstellning av 19-nor-steroider
SE7212974A SE385293B (sv) 1968-10-04 1969-10-03 Nya tricykliska foreningar till anvendning vid syntes av 19-nor-steroider och 9beta,10alfa-steroider
SE6913639A SE375304B (sv) 1968-10-04 1969-10-03
SE7212975A SE403910B (sv) 1968-10-04 1972-02-16 Mellanprodukter for framstellning av hormonalt verksamma 19-nor-steroider och 9beta,10alfa-steroider

Family Applications Before (4)

Application Number Title Priority Date Filing Date
SE7212973A SE385292B (sv) 1968-10-04 1969-10-03 Nya indanonderivat till anvendning som mellanprodukter vid syntes av 19-nor-steroider och 9beta,10alfa-steroider
SE7212972A SE381876B (sv) 1968-10-04 1969-10-03 Forfarande for framstellning av 19-nor-steroider
SE7212974A SE385293B (sv) 1968-10-04 1969-10-03 Nya tricykliska foreningar till anvendning vid syntes av 19-nor-steroider och 9beta,10alfa-steroider
SE6913639A SE375304B (sv) 1968-10-04 1969-10-03

Country Status (12)

Country Link
JP (1) JPS5636177B1 (sv)
AT (2) AT300209B (sv)
BE (1) BE739791A (sv)
CA (1) CA977351A (sv)
CH (4) CH576997A5 (sv)
DE (1) DE1950012C2 (sv)
DK (1) DK140588B (sv)
ES (2) ES372175A1 (sv)
FR (1) FR2019929A1 (sv)
GB (5) GB1265515A (sv)
NL (1) NL168225C (sv)
SE (5) SE385292B (sv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2165320C2 (de) * 1971-12-24 1982-09-16 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von Bicycloalkan-thio-Derivaten
DE2449031C2 (de) * 1974-10-11 1983-08-04 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 13β-Alkyl-4-gonen-3,17-dionen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1364556A (fr) * 1962-03-06 1964-06-26 Roussel Uclaf Nouveau procédé de synthèse de stéroïdes et de composés apparentés et produits utilisés dans ce procédé

Also Published As

Publication number Publication date
JPS5636177B1 (sv) 1981-08-22
BE739791A (sv) 1970-04-03
SE385292B (sv) 1976-06-21
DK140588C (sv) 1980-03-17
FR2019929A1 (sv) 1970-07-10
DE1950012A1 (de) 1970-04-09
DE1950012C2 (de) 1982-05-19
ES372175A1 (es) 1972-02-16
CA977351A (en) 1975-11-04
SE385293B (sv) 1976-06-21
GB1265512A (sv) 1972-03-01
GB1265516A (sv) 1972-03-01
CH582123A5 (sv) 1976-11-30
NL6914990A (sv) 1970-04-07
DK140588B (da) 1979-10-08
AT300209B (de) 1972-07-25
NL168225C (nl) 1982-03-16
CH576997A5 (sv) 1976-06-30
CH565130A5 (sv) 1975-08-15
CH572943A5 (sv) 1976-02-27
ES400149A1 (es) 1975-03-16
AT311569B (de) 1973-11-26
SE375304B (sv) 1975-04-14
SE381876B (sv) 1975-12-22
GB1265514A (sv) 1972-03-01
GB1265513A (sv) 1972-03-01
NL168225B (nl) 1981-10-16
GB1265515A (sv) 1972-03-01

Similar Documents

Publication Publication Date Title
IL31447A0 (en) Anti-inflammatory steroids of the pregnane series
FI46376C (sv) Förfarande för framställning av steroid-(17alfa,16alfa-d)-oxazolidiner och steroid-(17alfa,16alfa-d)-oxazolidinoxaziner
IL33026A0 (en) Process for the production of 2-acyloxy-thionobenzamides,and new 2-acyloxy-thionobenzamides
SE403910B (sv) Mellanprodukter for framstellning av hormonalt verksamma 19-nor-steroider och 9beta,10alfa-steroider
CA955245A (en) Steroids and process for their manufacture
IL34976A0 (en) New 21,21-dichloro steroids of the pregnane series
FI48347C (sv) Förfarande för framställning av 17beta-alkanoyloxi-17alfa-propadienyl- steroider.
CA918636A (en) Steroids of the pregnane series
DK120540B (da) Fremgangsmåde til fremstilling af 17α-alkynyl-17β-acyloxysteroider af androstan- eller estranrækken.
IL34053A0 (en) New 21-halogensteroids of the pregnane series
CA947275A (en) 18-methylene-steroids of the pregnane series and process for their manufacture
IL32219A0 (en) 9beta,10alpha-steroids of the pregnane series
SE386903B (sv) Forfarande for framstellning av beta-11-klorsubstituerade steroider tillhorande pregnanserien
FI47094C (sv) Förfarande för framställning av steroid-spirocyklobutanoner.
CA792233A (en) Steroid derivatives of the pregnane or allopregnane series
CA780848A (en) Process and 5-oxygenated inter-mediates for the manufacture of 19-norsteroids of the androstane series
CA779285A (en) 1,2.alpha.-METHYLENE STEROIDS OF THE PREGNANE SERIES AND PROCESS FOR THEIR MANUFACTURE
IL33017A0 (en) 6,9,21-trihalogenosteroids of the pregnane series
CA785753A (en) Carbalkoxyhydrazones of the androstane series
CA781457A (en) 7.alpha.,17,17-TRIMETHYL-3-ENE STEROIDS OF THE ANDROSTANE AND 19-NORANDROSTANE SERIES AND PROCESS FOR THEIR PREPARATION
CA787417A (en) 19-alkyl steroids and process for the manufacture thereof
NL154185B (nl) Werkwijze ter bereiding van vuurvaste sinterprodukten, alsmede met deze produkten vervaardigde voorwerpen.
ZA693904B (en) Aldehydes of the pregnane series and process for their manufacture
CA774788A (en) Double dress construction and method for its manufacture
IL23951A (en) 9beta,10alpha-steroids of the androstane and pregnane series and processes for the manufacture thereof