SE395892B - Forfarande for framstellning av piperidyl-bensimidazoliner med terapeutisk verkan - Google Patents

Forfarande for framstellning av piperidyl-bensimidazoliner med terapeutisk verkan

Info

Publication number
SE395892B
SE395892B SE7210999A SE1099972A SE395892B SE 395892 B SE395892 B SE 395892B SE 7210999 A SE7210999 A SE 7210999A SE 1099972 A SE1099972 A SE 1099972A SE 395892 B SE395892 B SE 395892B
Authority
SE
Sweden
Prior art keywords
bensimidazolines
piperidyl
procedure
preparation
therapeutic effect
Prior art date
Application number
SE7210999A
Other languages
English (en)
Swedish (sv)
Inventor
I Maruyama
M Nakao
K Sasajima
I Yanagihara
S Inaba
H Yamamoto
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Publication of SE395892B publication Critical patent/SE395892B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/52Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE7210999A 1971-08-26 1972-08-24 Forfarande for framstellning av piperidyl-bensimidazoliner med terapeutisk verkan SE395892B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6564171A JPS5511671B2 (xx) 1971-08-26 1971-08-26

Publications (1)

Publication Number Publication Date
SE395892B true SE395892B (sv) 1977-08-29

Family

ID=13292836

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7210999A SE395892B (sv) 1971-08-26 1972-08-24 Forfarande for framstellning av piperidyl-bensimidazoliner med terapeutisk verkan
SE7505022A SE399263B (sv) 1971-08-26 1975-04-29 Analogiforfarande for framstellning av triazaspirodekaner med terapeutisk verkan

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE7505022A SE399263B (sv) 1971-08-26 1975-04-29 Analogiforfarande for framstellning av triazaspirodekaner med terapeutisk verkan

Country Status (11)

Country Link
US (1) US3840529A (xx)
JP (1) JPS5511671B2 (xx)
AU (1) AU451875B2 (xx)
BE (1) BE788050A (xx)
CA (1) CA986105A (xx)
CH (1) CH551413A (xx)
DE (1) DE2264668A1 (xx)
FR (1) FR2150880B1 (xx)
GB (1) GB1363195A (xx)
NL (1) NL7211619A (xx)
SE (2) SE395892B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4080328A (en) * 1971-07-13 1978-03-21 Sumitomo Chemical Company, Limited N-substituted heterocyclic derivatives and preparation thereof
CA1012540A (en) * 1972-06-17 1977-06-21 Sumitomo Chemical Company 2-propanol derivatives and preparation thereof
US3894030A (en) * 1973-01-04 1975-07-08 Janssen Pharmaceutica Nv 1-{8 1-(2-Hydroxy-3-aryloxypropyl)-4-piperidyl{9 -2-benzimidazolinones and related compounds
AT344695B (de) * 1974-02-28 1978-08-10 Sumitomo Chemical Co Verfahren zur herstellung neuer phenoxypropylaminderivate und ihrer salze
US3989707A (en) * 1974-06-21 1976-11-02 Janssen Pharmaceutica N.V. Benzimidazolinone derivatives
US3996362A (en) * 1975-05-28 1976-12-07 E. R. Squibb & Sons, Inc. 2-[[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-(piperidinyl or 1,2,3,6-tetrahydro-1-pyridinyl)]alkyl]-1H-benz[de]isoquinoline-1,3(2H)-diones
JPS6026783B2 (ja) * 1975-06-03 1985-06-25 ウェルファイド株式会社 新規な有機化合物の製造法
US3996363A (en) * 1975-06-13 1976-12-07 E. R. Squibb & Sons, Inc. 2-[(4-Oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)alkyl]-1H-benz[de]isoquinolin-1,3(2H)-diones
JPS58148719U (ja) * 1982-03-26 1983-10-06 赤井電機株式会社 磁気ヘツド
US5032312A (en) * 1989-04-20 1991-07-16 Hoffmann-La Roche Inc. 3E-cyclohexylalkoxy derivatives

Also Published As

Publication number Publication date
SE399263B (sv) 1978-02-06
BE788050A (fr) 1972-12-18
JPS4832878A (xx) 1973-05-02
JPS5511671B2 (xx) 1980-03-26
AU451875B2 (en) 1974-08-22
AU4594572A (en) 1974-02-28
DE2241566B2 (de) 1975-09-25
SE7505022L (xx) 1975-04-29
FR2150880B1 (xx) 1975-10-17
CA986105A (en) 1976-03-23
CH551413A (fr) 1974-07-15
NL7211619A (xx) 1973-02-28
DE2264668A1 (de) 1975-03-20
FR2150880A1 (xx) 1973-04-13
DE2241566A1 (de) 1973-04-19
GB1363195A (en) 1974-08-14
US3840529A (en) 1974-10-08

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