SE387122B - Forfarande for framstellning av pyrano(3,4-b)indol- eller tiopyrano(3,4-b)indolderivat med terapeutisk verkan - Google Patents
Forfarande for framstellning av pyrano(3,4-b)indol- eller tiopyrano(3,4-b)indolderivat med terapeutisk verkanInfo
- Publication number
- SE387122B SE387122B SE7207142A SE714272A SE387122B SE 387122 B SE387122 B SE 387122B SE 7207142 A SE7207142 A SE 7207142A SE 714272 A SE714272 A SE 714272A SE 387122 B SE387122 B SE 387122B
- Authority
- SE
- Sweden
- Prior art keywords
- tiopyrano
- pyrano
- indole
- procedure
- preparation
- Prior art date
Links
- DULBEIKUQPJAST-UHFFFAOYSA-N pyrano[3,4-b]indole Chemical compound O1C=CC2=C3C=CC=CC3=NC2=C1 DULBEIKUQPJAST-UHFFFAOYSA-N 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L29/00—Semiconductor devices specially adapted for rectifying, amplifying, oscillating or switching and having potential barriers; Capacitors or resistors having potential barriers, e.g. a PN-junction depletion layer or carrier concentration layer; Details of semiconductor bodies or of electrodes thereof ; Multistep manufacturing processes therefor
- H01L29/66—Types of semiconductor device ; Multistep manufacturing processes therefor
- H01L29/68—Types of semiconductor device ; Multistep manufacturing processes therefor controllable by only the electric current supplied, or only the electric potential applied, to an electrode which does not carry the current to be rectified, amplified or switched
- H01L29/70—Bipolar devices
- H01L29/72—Transistor-type devices, i.e. able to continuously respond to applied control signals
- H01L29/73—Bipolar junction transistors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Power Engineering (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Engineering & Computer Science (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Computer Hardware Design (AREA)
- Ceramic Engineering (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US00148895A US3843681A (en) | 1971-06-01 | 1971-06-01 | 1-carboxamido pyrano(thiopyrano)(3,4-6)indole derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
SE387122B true SE387122B (sv) | 1976-08-30 |
Family
ID=22527916
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7207142A SE387122B (sv) | 1971-06-01 | 1972-05-31 | Forfarande for framstellning av pyrano(3,4-b)indol- eller tiopyrano(3,4-b)indolderivat med terapeutisk verkan |
Country Status (23)
Country | Link |
---|---|
US (1) | US3843681A (cs) |
JP (1) | JPS5638594B1 (cs) |
AR (1) | AR198787A1 (cs) |
AU (1) | AU463079B2 (cs) |
BE (1) | BE784284A (cs) |
CA (1) | CA1006875A (cs) |
CH (1) | CH580101A5 (cs) |
CS (1) | CS178409B2 (cs) |
DE (1) | DE2226340A1 (cs) |
DK (1) | DK155328C (cs) |
ES (1) | ES403343A1 (cs) |
FI (1) | FI54125C (cs) |
FR (1) | FR2140154B1 (cs) |
GB (1) | GB1391005A (cs) |
HK (1) | HK13078A (cs) |
HU (1) | HU169432B (cs) |
IL (1) | IL39466A (cs) |
MY (1) | MY7800237A (cs) |
NL (1) | NL173405C (cs) |
PH (2) | PH10625A (cs) |
SE (1) | SE387122B (cs) |
SU (1) | SU463262A3 (cs) |
ZA (1) | ZA723344B (cs) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3974179A (en) * | 1971-06-01 | 1976-08-10 | American Home Products Corporation | 1,3,4,9-Tetrahydropyrano[3,4-b]indole-1-acetamides and derivatives |
US4118394A (en) * | 1976-10-18 | 1978-10-03 | Ayerst, Mckenna & Harrison Limited | Pyrano- and thiopyranoindole derivatives |
US4179503A (en) * | 1978-05-08 | 1979-12-18 | American Home Products Corp. | 1-Hydroxyalkanamine pyrano[3,4-b]indole derivatives |
US4309348A (en) * | 1979-05-14 | 1982-01-05 | American Home Products Corporation | Tricyclic indole derivatives |
US4319029A (en) * | 1979-08-06 | 1982-03-09 | American Home Products Corporation | Hydroxyalkanamide tetrahydrocarbazoles |
US4235903A (en) * | 1979-08-06 | 1980-11-25 | American Home Products Corporation | 1-Hydroxyalkanamine tetrahydrocarbazoles and cyclopent[b]indoles, compositions and method of use |
JPS58179164A (ja) * | 1982-04-10 | 1983-10-20 | Toshiharu Nakai | 金属表面処理等に用いられるscr整流器の定格直流電圧選定方法並びに定格直流電圧切替方法 |
US4670462A (en) * | 1986-03-11 | 1987-06-02 | American Home Products Corporation | Substituted 1,3,4,9-tetrahydropyrano(3,4-B)indole-1-acetic acids |
US4971960A (en) * | 1986-03-11 | 1990-11-20 | American Home Products Corporation | Substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids |
US4826994A (en) * | 1986-03-11 | 1989-05-02 | American Home Products Corporation | Production of substituted 1,3,4,9-tetrahydropyrano(3,4-B)indole-1-acetic acids |
US4775690A (en) * | 1987-01-13 | 1988-10-04 | American Home Products Corporation | Substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids |
US4663345A (en) * | 1986-04-17 | 1987-05-05 | American Home Products Corporation | Etodolac for treatment of gout |
US4748252A (en) * | 1986-08-15 | 1988-05-31 | American Home Products Corporation | Substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids |
US4686213A (en) * | 1986-08-15 | 1987-08-11 | American Home Products Corporation | Substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids |
US4810699A (en) * | 1987-02-20 | 1989-03-07 | American Home Products Corporation | Substituted 1,3,4,9-tetrahydropyrano[3,4,-b]indole-1-acetic acids, pharmaceutical compositions containing them, and methods for treating inflammatory conditions and for analgesic purposes using them |
US4824961A (en) * | 1987-08-27 | 1989-04-25 | American Home Products Corporation | Production of substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids |
US4897493A (en) * | 1987-08-27 | 1990-01-30 | American Home Products Corporation | Production of substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids |
US4822781A (en) * | 1987-10-08 | 1989-04-18 | American Home Products | Substituted-8-alkenyl-1,3,4,9-tetrahydropyrano-[3,4-b]indole-1-acetic acids |
US4822893A (en) * | 1988-02-08 | 1989-04-18 | American Home Products | Production of substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids |
US4873257A (en) * | 1988-04-21 | 1989-10-10 | American Home Products Corporation | Susbtituted fused tetrahydrocarbazole acetic acid derivatives |
EP0727994B1 (en) * | 1992-03-13 | 2000-06-07 | Sepracor, Inc. | Antipyretic and analgesic methods and compositions containing optically pure r-etodolac |
IT1288123B1 (it) * | 1996-09-04 | 1998-09-10 | Nicox Sa | Uso di nitroderivati per l'incontinenza urinaria |
US6103765A (en) * | 1997-07-09 | 2000-08-15 | Androsolutions, Inc. | Methods for treating male erectile dysfunction |
JP2001509480A (ja) | 1997-07-09 | 2001-07-24 | アンドロソリューションズ,インク. | 男性勃起機能不全を治療するための改良された方法及び組成物 |
ES2255287T3 (es) | 1998-07-09 | 2006-06-16 | Cephalon, Inc. | Composiciones para el tratamiento de la leucemia linfocitica cronica. |
US6066741A (en) * | 1998-09-08 | 2000-05-23 | A.M.S.A. Anonima Materie Sintetiche & Affini S.P.A. | Process for the preparation of etodolac |
IT1308633B1 (it) | 1999-03-02 | 2002-01-09 | Nicox Sa | Nitrossiderivati. |
US7361680B2 (en) * | 1999-07-23 | 2008-04-22 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
US7151100B1 (en) | 1999-07-23 | 2006-12-19 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
US7105560B1 (en) | 1999-07-23 | 2006-09-12 | The Regents Of The University Of California | Use of etodolac in the treatment of multiple myeloma |
US7129262B2 (en) * | 1999-07-23 | 2006-10-31 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
US6545034B1 (en) | 1999-07-23 | 2003-04-08 | The Regents Of The University Of California | Use of etodolac for the treatment of chronic lymphocytic leukemia |
IT1318673B1 (it) * | 2000-08-08 | 2003-08-27 | Nicox Sa | Farmaci per le disfunzioni sessuali. |
IT1318674B1 (it) * | 2000-08-08 | 2003-08-27 | Nicox Sa | Faramaci per l'incontinenza. |
AU8322401A (en) * | 2000-08-09 | 2002-02-18 | Univ California | Indole compounds useful for the treatment of cancer |
US20040152672A1 (en) * | 2000-08-09 | 2004-08-05 | Carson Dennis A. | Indole compounds useful for the treatment of cancer |
US6544556B1 (en) | 2000-09-11 | 2003-04-08 | Andrx Corporation | Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor |
US20030232794A1 (en) * | 2001-06-26 | 2003-12-18 | Cottam Howard B. | Use of STAT-6 inhibitors as therapeutic agents |
US7601846B2 (en) * | 2001-06-26 | 2009-10-13 | The Regents Of The University Of California | Compounds having activity as inhibitors of apoptosis |
EP2266590A3 (en) | 2002-02-22 | 2011-04-20 | Shire LLC | Active agent delivery sytems and methods for protecting and administering active agents |
ITMI20020773A1 (it) * | 2002-04-11 | 2003-10-13 | Nicox Sa | Farmaci per il trattamento dell'artrite |
TW200400963A (en) | 2002-05-21 | 2004-01-16 | Wyeth Corp | R-enantiomers of pyranoindole derivatives and the use thereof for the treatment of hepatitis C virus infection or disease |
TW200400818A (en) | 2002-05-21 | 2004-01-16 | Wyeth Corp | Method for the use of pyranoindole derivatives to treat infection with hepatitis C virus |
WO2004026116A2 (en) * | 2002-09-19 | 2004-04-01 | The Regents Of The University Of California | Use of etodoclac to treat hyperplasia |
DE10252667A1 (de) * | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
TW200524940A (en) * | 2003-10-02 | 2005-08-01 | Salmedix Inc | Indole derivatives |
WO2006031770A1 (en) * | 2004-09-10 | 2006-03-23 | Wyeth | Process for the scalable synthesis of 1, 3, 4, 9-tetrahydropyrano[3, 4-b]-indole derivatives |
EP1683521A1 (en) * | 2005-01-21 | 2006-07-26 | Centre National De La Recherche Scientifique (Cnrs) | Peptide deformylase inhibitors, their use, and pharmaceutical compositions containing the same |
JP2009529057A (ja) | 2006-03-08 | 2009-08-13 | コートリア・コーポレーシヨン | Cox−関連胃損傷を予防するための非−選択的cox阻害剤との組み合わせ療法 |
CN104311472B9 (zh) * | 2008-07-23 | 2020-03-17 | 艾尼纳制药公司 | 经取代的1,2,3,4-四氢环戊并[b]吲哚-3-基乙酸衍生物 |
-
1971
- 1971-06-01 US US00148895A patent/US3843681A/en not_active Expired - Lifetime
-
1972
- 1972-05-16 ZA ZA723344A patent/ZA723344B/xx unknown
- 1972-05-17 IL IL39466A patent/IL39466A/xx unknown
- 1972-05-22 AU AU42554/72A patent/AU463079B2/en not_active Ceased
- 1972-05-24 PH PH13564A patent/PH10625A/en unknown
- 1972-05-30 DE DE2226340A patent/DE2226340A1/de active Granted
- 1972-05-30 FI FI1511/72A patent/FI54125C/fi active
- 1972-05-31 CS CS3759A patent/CS178409B2/cs unknown
- 1972-05-31 DK DK271972A patent/DK155328C/da not_active IP Right Cessation
- 1972-05-31 CA CA143,820A patent/CA1006875A/en not_active Expired
- 1972-05-31 SU SU1792255A patent/SU463262A3/ru active
- 1972-05-31 SE SE7207142A patent/SE387122B/xx unknown
- 1972-05-31 ES ES403343A patent/ES403343A1/es not_active Expired
- 1972-05-31 AR AR242297A patent/AR198787A1/es active
- 1972-06-01 NL NLAANVRAGE7207408,A patent/NL173405C/xx not_active IP Right Cessation
- 1972-06-01 CH CH813372A patent/CH580101A5/xx not_active IP Right Cessation
- 1972-06-01 FR FR7219699A patent/FR2140154B1/fr not_active Expired
- 1972-06-01 HU HUAE361A patent/HU169432B/hu unknown
- 1972-06-01 BE BE784284A patent/BE784284A/xx not_active IP Right Cessation
- 1972-06-01 GB GB2560572A patent/GB1391005A/en not_active Expired
- 1972-06-01 JP JP5474472A patent/JPS5638594B1/ja active Pending
-
1975
- 1975-03-24 PH PH16956A patent/PH11673A/en unknown
-
1978
- 1978-03-09 HK HK130/78A patent/HK13078A/xx unknown
- 1978-12-30 MY MY237/78A patent/MY7800237A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
FR2140154A1 (cs) | 1973-01-12 |
AU463079B2 (en) | 1975-07-17 |
IL39466A0 (en) | 1972-07-26 |
DK155328B (da) | 1989-03-28 |
AU4255472A (en) | 1973-11-29 |
CS178409B2 (cs) | 1977-09-15 |
HK13078A (en) | 1978-03-17 |
NL173405C (nl) | 1984-01-16 |
AR198787A1 (es) | 1974-07-24 |
GB1391005A (en) | 1975-04-16 |
BE784284A (fr) | 1972-12-01 |
SU463262A3 (ru) | 1975-03-05 |
ZA723344B (en) | 1973-12-19 |
US3843681A (en) | 1974-10-22 |
MY7800237A (en) | 1978-12-31 |
FR2140154B1 (cs) | 1976-04-16 |
PH10625A (en) | 1977-07-21 |
CH580101A5 (cs) | 1976-09-30 |
FI54125B (fi) | 1978-06-30 |
HU169432B (cs) | 1976-11-28 |
FI54125C (fi) | 1978-10-10 |
JPS5638594B1 (cs) | 1981-09-08 |
CA1006875A (en) | 1977-03-15 |
DE2226340C2 (cs) | 1987-07-16 |
ES403343A1 (es) | 1975-04-16 |
DK155328C (da) | 1989-09-18 |
PH11673A (en) | 1978-05-19 |
IL39466A (en) | 1975-05-22 |
DE2226340A1 (de) | 1973-03-15 |
NL7207408A (cs) | 1972-12-05 |
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