SE387122B - Forfarande for framstellning av pyrano(3,4-b)indol- eller tiopyrano(3,4-b)indolderivat med terapeutisk verkan - Google Patents

Forfarande for framstellning av pyrano(3,4-b)indol- eller tiopyrano(3,4-b)indolderivat med terapeutisk verkan

Info

Publication number
SE387122B
SE387122B SE7207142A SE714272A SE387122B SE 387122 B SE387122 B SE 387122B SE 7207142 A SE7207142 A SE 7207142A SE 714272 A SE714272 A SE 714272A SE 387122 B SE387122 B SE 387122B
Authority
SE
Sweden
Prior art keywords
tiopyrano
pyrano
indole
procedure
preparation
Prior art date
Application number
SE7207142A
Other languages
English (en)
Swedish (sv)
Inventor
C A Demerson
L G Humber
T A Dobson
I L Jirkovsky
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22527916&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE387122(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by American Home Prod filed Critical American Home Prod
Publication of SE387122B publication Critical patent/SE387122B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10D—INORGANIC ELECTRIC SEMICONDUCTOR DEVICES
    • H10D10/00—Bipolar junction transistors [BJT]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
SE7207142A 1971-06-01 1972-05-31 Forfarande for framstellning av pyrano(3,4-b)indol- eller tiopyrano(3,4-b)indolderivat med terapeutisk verkan SE387122B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00148895A US3843681A (en) 1971-06-01 1971-06-01 1-carboxamido pyrano(thiopyrano)(3,4-6)indole derivatives

Publications (1)

Publication Number Publication Date
SE387122B true SE387122B (sv) 1976-08-30

Family

ID=22527916

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7207142A SE387122B (sv) 1971-06-01 1972-05-31 Forfarande for framstellning av pyrano(3,4-b)indol- eller tiopyrano(3,4-b)indolderivat med terapeutisk verkan

Country Status (23)

Country Link
US (1) US3843681A (cs)
JP (1) JPS5638594B1 (cs)
AR (1) AR198787A1 (cs)
AU (1) AU463079B2 (cs)
BE (1) BE784284A (cs)
CA (1) CA1006875A (cs)
CH (1) CH580101A5 (cs)
CS (1) CS178409B2 (cs)
DE (1) DE2226340A1 (cs)
DK (1) DK155328C (cs)
ES (1) ES403343A1 (cs)
FI (1) FI54125C (cs)
FR (1) FR2140154B1 (cs)
GB (1) GB1391005A (cs)
HK (1) HK13078A (cs)
HU (1) HU169432B (cs)
IL (1) IL39466A (cs)
MY (1) MY7800237A (cs)
NL (1) NL173405C (cs)
PH (2) PH10625A (cs)
SE (1) SE387122B (cs)
SU (1) SU463262A3 (cs)
ZA (1) ZA723344B (cs)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3974179A (en) * 1971-06-01 1976-08-10 American Home Products Corporation 1,3,4,9-Tetrahydropyrano[3,4-b]indole-1-acetamides and derivatives
US4118394A (en) * 1976-10-18 1978-10-03 Ayerst, Mckenna & Harrison Limited Pyrano- and thiopyranoindole derivatives
US4179503A (en) * 1978-05-08 1979-12-18 American Home Products Corp. 1-Hydroxyalkanamine pyrano[3,4-b]indole derivatives
US4309348A (en) * 1979-05-14 1982-01-05 American Home Products Corporation Tricyclic indole derivatives
US4319029A (en) * 1979-08-06 1982-03-09 American Home Products Corporation Hydroxyalkanamide tetrahydrocarbazoles
US4235903A (en) * 1979-08-06 1980-11-25 American Home Products Corporation 1-Hydroxyalkanamine tetrahydrocarbazoles and cyclopent[b]indoles, compositions and method of use
JPS58179164A (ja) * 1982-04-10 1983-10-20 Toshiharu Nakai 金属表面処理等に用いられるｓｃｒ整流器の定格直流電圧選定方法並びに定格直流電圧切替方法
US4971960A (en) * 1986-03-11 1990-11-20 American Home Products Corporation Substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids
US4775690A (en) * 1987-01-13 1988-10-04 American Home Products Corporation Substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids
US4826994A (en) * 1986-03-11 1989-05-02 American Home Products Corporation Production of substituted 1,3,4,9-tetrahydropyrano(3,4-B)indole-1-acetic acids
US4670462A (en) * 1986-03-11 1987-06-02 American Home Products Corporation Substituted 1,3,4,9-tetrahydropyrano(3,4-B)indole-1-acetic acids
US4663345A (en) * 1986-04-17 1987-05-05 American Home Products Corporation Etodolac for treatment of gout
US4686213A (en) * 1986-08-15 1987-08-11 American Home Products Corporation Substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids
US4748252A (en) * 1986-08-15 1988-05-31 American Home Products Corporation Substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids
US4810699A (en) * 1987-02-20 1989-03-07 American Home Products Corporation Substituted 1,3,4,9-tetrahydropyrano[3,4,-b]indole-1-acetic acids, pharmaceutical compositions containing them, and methods for treating inflammatory conditions and for analgesic purposes using them
US4897493A (en) * 1987-08-27 1990-01-30 American Home Products Corporation Production of substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids
US4824961A (en) * 1987-08-27 1989-04-25 American Home Products Corporation Production of substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids
US4822781A (en) * 1987-10-08 1989-04-18 American Home Products Substituted-8-alkenyl-1,3,4,9-tetrahydropyrano-[3,4-b]indole-1-acetic acids
US4822893A (en) * 1988-02-08 1989-04-18 American Home Products Production of substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids
US4873257A (en) * 1988-04-21 1989-10-10 American Home Products Corporation Susbtituted fused tetrahydrocarbazole acetic acid derivatives
ATE193648T1 (de) * 1992-03-13 2000-06-15 Sepracor Inc Antipyretische und analgetische verfahren und zusammensetzungen, die optisch reines r-etodolac enthalten
IT1288123B1 (it) * 1996-09-04 1998-09-10 Nicox Sa Uso di nitroderivati per l'incontinenza urinaria
KR20010021625A (ko) 1997-07-09 2001-03-15 추후보정 개선된 남성발기 기능장애 치료방법 및 그 조성물
US6103765A (en) 1997-07-09 2000-08-15 Androsolutions, Inc. Methods for treating male erectile dysfunction
JP2002520282A (ja) 1998-07-09 2002-07-09 フランシス エイ． ナーデラ， 慢性リンパ性白血病の処置のための方法および組成物
US6066741A (en) * 1998-09-08 2000-05-23 A.M.S.A. Anonima Materie Sintetiche & Affini S.P.A. Process for the preparation of etodolac
IT1308633B1 (it) 1999-03-02 2002-01-09 Nicox Sa Nitrossiderivati.
US7105560B1 (en) * 1999-07-23 2006-09-12 The Regents Of The University Of California Use of etodolac in the treatment of multiple myeloma
US7129262B2 (en) * 1999-07-23 2006-10-31 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US7151100B1 (en) 1999-07-23 2006-12-19 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US7361680B2 (en) * 1999-07-23 2008-04-22 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US6545034B1 (en) 1999-07-23 2003-04-08 The Regents Of The University Of California Use of etodolac for the treatment of chronic lymphocytic leukemia
IT1318674B1 (it) * 2000-08-08 2003-08-27 Nicox Sa Faramaci per l'incontinenza.
IT1318673B1 (it) * 2000-08-08 2003-08-27 Nicox Sa Farmaci per le disfunzioni sessuali.
US20040152672A1 (en) * 2000-08-09 2004-08-05 Carson Dennis A. Indole compounds useful for the treatment of cancer
AU2001283224B2 (en) * 2000-08-09 2007-06-28 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US6544556B1 (en) 2000-09-11 2003-04-08 Andrx Corporation Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor
US7601846B2 (en) * 2001-06-26 2009-10-13 The Regents Of The University Of California Compounds having activity as inhibitors of apoptosis
US20030232794A1 (en) * 2001-06-26 2003-12-18 Cottam Howard B. Use of STAT-6 inhibitors as therapeutic agents
EP2316469A1 (en) 2002-02-22 2011-05-04 Shire LLC Delivery system and methods for protecting and administering dextroamphetamine
ITMI20020773A1 (it) * 2002-04-11 2003-10-13 Nicox Sa Farmaci per il trattamento dell'artrite
TW200400963A (en) 2002-05-21 2004-01-16 Wyeth Corp R-enantiomers of pyranoindole derivatives and the use thereof for the treatment of hepatitis C virus infection or disease
TW200400818A (en) 2002-05-21 2004-01-16 Wyeth Corp Method for the use of pyranoindole derivatives to treat infection with hepatitis C virus
US7211599B2 (en) * 2002-09-19 2007-05-01 The Regents Of The University Of California Use of etodolac to treat hyperplasia
DE10252667A1 (de) * 2002-11-11 2004-05-27 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
WO2005033113A2 (en) * 2003-10-02 2005-04-14 Cephalon, Inc Indole derivatives
DE10360792A1 (de) * 2003-12-23 2005-07-28 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
EP1786772A1 (en) * 2004-09-10 2007-05-23 Wyeth a Corporation of the State of Delaware Process for the scalable synthesis of 1, 3, 4, 9-tetrahydropyranoý3, 4-b¨-indole derivatives
EP1683521A1 (en) * 2005-01-21 2006-07-26 Centre National De La Recherche Scientifique (Cnrs) Peptide deformylase inhibitors, their use, and pharmaceutical compositions containing the same
ES2418153T3 (es) 2006-03-08 2013-08-12 Cortria Corporation Terapia de combinación con inhibidores no selectivos de COX para prevenir lesiones gástricas relacionadas con COX
CN102164891B (zh) * 2008-07-23 2014-09-03 艾尼纳制药公司 可用于治疗自身免疫性疾病和炎性疾病的经取代的1,2,3,4-四氢环戊并[b]吲哚-3-基乙酸衍生物

Also Published As

Publication number Publication date
NL173405C (nl) 1984-01-16
CS178409B2 (cs) 1977-09-15
CH580101A5 (cs) 1976-09-30
AU4255472A (en) 1973-11-29
IL39466A (en) 1975-05-22
DE2226340C2 (cs) 1987-07-16
FR2140154B1 (cs) 1976-04-16
IL39466A0 (en) 1972-07-26
DE2226340A1 (de) 1973-03-15
AR198787A1 (es) 1974-07-24
FI54125C (fi) 1978-10-10
FI54125B (fi) 1978-06-30
DK155328C (da) 1989-09-18
FR2140154A1 (cs) 1973-01-12
SU463262A3 (ru) 1975-03-05
MY7800237A (en) 1978-12-31
DK155328B (da) 1989-03-28
US3843681A (en) 1974-10-22
CA1006875A (en) 1977-03-15
HU169432B (cs) 1976-11-28
ES403343A1 (es) 1975-04-16
AU463079B2 (en) 1975-07-17
BE784284A (fr) 1972-12-01
JPS5638594B1 (cs) 1981-09-08
HK13078A (en) 1978-03-17
ZA723344B (en) 1973-12-19
NL7207408A (cs) 1972-12-05
PH11673A (en) 1978-05-19
PH10625A (en) 1977-07-21
GB1391005A (en) 1975-04-16

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