IL39466A - Pyrano(3,4-b)-and thiopyrano(3,4-b)indole derivatives and their preparation - Google Patents
Pyrano(3,4-b)-and thiopyrano(3,4-b)indole derivatives and their preparationInfo
- Publication number
- IL39466A IL39466A IL39466A IL3946672A IL39466A IL 39466 A IL39466 A IL 39466A IL 39466 A IL39466 A IL 39466A IL 3946672 A IL3946672 A IL 3946672A IL 39466 A IL39466 A IL 39466A
- Authority
- IL
- Israel
- Prior art keywords
- thiopyrano
- pyrano
- preparation
- indole derivatives
- indole
- Prior art date
Links
- VLZVXVNGVZTXEI-UHFFFAOYSA-N thiopyrano[3,4-b]indole Chemical class S1C=CC2=C3C=CC=CC3=NC2=C1 VLZVXVNGVZTXEI-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- H—ELECTRICITY
- H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
- H10D—INORGANIC ELECTRIC SEMICONDUCTOR DEVICES
- H10D10/00—Bipolar junction transistors [BJT]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US00148895A US3843681A (en) | 1971-06-01 | 1971-06-01 | 1-carboxamido pyrano(thiopyrano)(3,4-6)indole derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
IL39466A0 IL39466A0 (en) | 1972-07-26 |
IL39466A true IL39466A (en) | 1975-05-22 |
Family
ID=22527916
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL39466A IL39466A (en) | 1971-06-01 | 1972-05-17 | Pyrano(3,4-b)-and thiopyrano(3,4-b)indole derivatives and their preparation |
Country Status (23)
Country | Link |
---|---|
US (1) | US3843681A (cs) |
JP (1) | JPS5638594B1 (cs) |
AR (1) | AR198787A1 (cs) |
AU (1) | AU463079B2 (cs) |
BE (1) | BE784284A (cs) |
CA (1) | CA1006875A (cs) |
CH (1) | CH580101A5 (cs) |
CS (1) | CS178409B2 (cs) |
DE (1) | DE2226340A1 (cs) |
DK (1) | DK155328C (cs) |
ES (1) | ES403343A1 (cs) |
FI (1) | FI54125C (cs) |
FR (1) | FR2140154B1 (cs) |
GB (1) | GB1391005A (cs) |
HK (1) | HK13078A (cs) |
HU (1) | HU169432B (cs) |
IL (1) | IL39466A (cs) |
MY (1) | MY7800237A (cs) |
NL (1) | NL173405C (cs) |
PH (2) | PH10625A (cs) |
SE (1) | SE387122B (cs) |
SU (1) | SU463262A3 (cs) |
ZA (1) | ZA723344B (cs) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3974179A (en) * | 1971-06-01 | 1976-08-10 | American Home Products Corporation | 1,3,4,9-Tetrahydropyrano[3,4-b]indole-1-acetamides and derivatives |
US4118394A (en) * | 1976-10-18 | 1978-10-03 | Ayerst, Mckenna & Harrison Limited | Pyrano- and thiopyranoindole derivatives |
US4179503A (en) * | 1978-05-08 | 1979-12-18 | American Home Products Corp. | 1-Hydroxyalkanamine pyrano[3,4-b]indole derivatives |
US4309348A (en) * | 1979-05-14 | 1982-01-05 | American Home Products Corporation | Tricyclic indole derivatives |
US4319029A (en) * | 1979-08-06 | 1982-03-09 | American Home Products Corporation | Hydroxyalkanamide tetrahydrocarbazoles |
US4235903A (en) * | 1979-08-06 | 1980-11-25 | American Home Products Corporation | 1-Hydroxyalkanamine tetrahydrocarbazoles and cyclopent[b]indoles, compositions and method of use |
JPS58179164A (ja) * | 1982-04-10 | 1983-10-20 | Toshiharu Nakai | 金属表面処理等に用いられるscr整流器の定格直流電圧選定方法並びに定格直流電圧切替方法 |
US4971960A (en) * | 1986-03-11 | 1990-11-20 | American Home Products Corporation | Substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids |
US4775690A (en) * | 1987-01-13 | 1988-10-04 | American Home Products Corporation | Substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids |
US4826994A (en) * | 1986-03-11 | 1989-05-02 | American Home Products Corporation | Production of substituted 1,3,4,9-tetrahydropyrano(3,4-B)indole-1-acetic acids |
US4670462A (en) * | 1986-03-11 | 1987-06-02 | American Home Products Corporation | Substituted 1,3,4,9-tetrahydropyrano(3,4-B)indole-1-acetic acids |
US4663345A (en) * | 1986-04-17 | 1987-05-05 | American Home Products Corporation | Etodolac for treatment of gout |
US4686213A (en) * | 1986-08-15 | 1987-08-11 | American Home Products Corporation | Substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids |
US4748252A (en) * | 1986-08-15 | 1988-05-31 | American Home Products Corporation | Substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids |
US4810699A (en) * | 1987-02-20 | 1989-03-07 | American Home Products Corporation | Substituted 1,3,4,9-tetrahydropyrano[3,4,-b]indole-1-acetic acids, pharmaceutical compositions containing them, and methods for treating inflammatory conditions and for analgesic purposes using them |
US4897493A (en) * | 1987-08-27 | 1990-01-30 | American Home Products Corporation | Production of substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids |
US4824961A (en) * | 1987-08-27 | 1989-04-25 | American Home Products Corporation | Production of substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids |
US4822781A (en) * | 1987-10-08 | 1989-04-18 | American Home Products | Substituted-8-alkenyl-1,3,4,9-tetrahydropyrano-[3,4-b]indole-1-acetic acids |
US4822893A (en) * | 1988-02-08 | 1989-04-18 | American Home Products | Production of substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids |
US4873257A (en) * | 1988-04-21 | 1989-10-10 | American Home Products Corporation | Susbtituted fused tetrahydrocarbazole acetic acid derivatives |
ATE193648T1 (de) * | 1992-03-13 | 2000-06-15 | Sepracor Inc | Antipyretische und analgetische verfahren und zusammensetzungen, die optisch reines r-etodolac enthalten |
IT1288123B1 (it) * | 1996-09-04 | 1998-09-10 | Nicox Sa | Uso di nitroderivati per l'incontinenza urinaria |
KR20010021625A (ko) | 1997-07-09 | 2001-03-15 | 추후보정 | 개선된 남성발기 기능장애 치료방법 및 그 조성물 |
US6103765A (en) | 1997-07-09 | 2000-08-15 | Androsolutions, Inc. | Methods for treating male erectile dysfunction |
JP2002520282A (ja) | 1998-07-09 | 2002-07-09 | フランシス エイ. ナーデラ, | 慢性リンパ性白血病の処置のための方法および組成物 |
US6066741A (en) * | 1998-09-08 | 2000-05-23 | A.M.S.A. Anonima Materie Sintetiche & Affini S.P.A. | Process for the preparation of etodolac |
IT1308633B1 (it) | 1999-03-02 | 2002-01-09 | Nicox Sa | Nitrossiderivati. |
US7105560B1 (en) * | 1999-07-23 | 2006-09-12 | The Regents Of The University Of California | Use of etodolac in the treatment of multiple myeloma |
US7129262B2 (en) * | 1999-07-23 | 2006-10-31 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
US7151100B1 (en) | 1999-07-23 | 2006-12-19 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
US7361680B2 (en) * | 1999-07-23 | 2008-04-22 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
US6545034B1 (en) | 1999-07-23 | 2003-04-08 | The Regents Of The University Of California | Use of etodolac for the treatment of chronic lymphocytic leukemia |
IT1318674B1 (it) * | 2000-08-08 | 2003-08-27 | Nicox Sa | Faramaci per l'incontinenza. |
IT1318673B1 (it) * | 2000-08-08 | 2003-08-27 | Nicox Sa | Farmaci per le disfunzioni sessuali. |
US20040152672A1 (en) * | 2000-08-09 | 2004-08-05 | Carson Dennis A. | Indole compounds useful for the treatment of cancer |
AU2001283224B2 (en) * | 2000-08-09 | 2007-06-28 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
US6544556B1 (en) | 2000-09-11 | 2003-04-08 | Andrx Corporation | Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor |
US7601846B2 (en) * | 2001-06-26 | 2009-10-13 | The Regents Of The University Of California | Compounds having activity as inhibitors of apoptosis |
US20030232794A1 (en) * | 2001-06-26 | 2003-12-18 | Cottam Howard B. | Use of STAT-6 inhibitors as therapeutic agents |
EP2316469A1 (en) | 2002-02-22 | 2011-05-04 | Shire LLC | Delivery system and methods for protecting and administering dextroamphetamine |
ITMI20020773A1 (it) * | 2002-04-11 | 2003-10-13 | Nicox Sa | Farmaci per il trattamento dell'artrite |
TW200400963A (en) | 2002-05-21 | 2004-01-16 | Wyeth Corp | R-enantiomers of pyranoindole derivatives and the use thereof for the treatment of hepatitis C virus infection or disease |
TW200400818A (en) | 2002-05-21 | 2004-01-16 | Wyeth Corp | Method for the use of pyranoindole derivatives to treat infection with hepatitis C virus |
US7211599B2 (en) * | 2002-09-19 | 2007-05-01 | The Regents Of The University Of California | Use of etodolac to treat hyperplasia |
DE10252667A1 (de) * | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
WO2005033113A2 (en) * | 2003-10-02 | 2005-04-14 | Cephalon, Inc | Indole derivatives |
DE10360792A1 (de) * | 2003-12-23 | 2005-07-28 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
EP1786772A1 (en) * | 2004-09-10 | 2007-05-23 | Wyeth a Corporation of the State of Delaware | Process for the scalable synthesis of 1, 3, 4, 9-tetrahydropyranoý3, 4-b¨-indole derivatives |
EP1683521A1 (en) * | 2005-01-21 | 2006-07-26 | Centre National De La Recherche Scientifique (Cnrs) | Peptide deformylase inhibitors, their use, and pharmaceutical compositions containing the same |
ES2418153T3 (es) | 2006-03-08 | 2013-08-12 | Cortria Corporation | Terapia de combinación con inhibidores no selectivos de COX para prevenir lesiones gástricas relacionadas con COX |
CN102164891B (zh) * | 2008-07-23 | 2014-09-03 | 艾尼纳制药公司 | 可用于治疗自身免疫性疾病和炎性疾病的经取代的1,2,3,4-四氢环戊并[b]吲哚-3-基乙酸衍生物 |
-
1971
- 1971-06-01 US US00148895A patent/US3843681A/en not_active Expired - Lifetime
-
1972
- 1972-05-16 ZA ZA723344A patent/ZA723344B/xx unknown
- 1972-05-17 IL IL39466A patent/IL39466A/xx unknown
- 1972-05-22 AU AU42554/72A patent/AU463079B2/en not_active Ceased
- 1972-05-24 PH PH13564A patent/PH10625A/en unknown
- 1972-05-30 DE DE2226340A patent/DE2226340A1/de active Granted
- 1972-05-30 FI FI1511/72A patent/FI54125C/fi active
- 1972-05-31 ES ES403343A patent/ES403343A1/es not_active Expired
- 1972-05-31 SU SU1792255A patent/SU463262A3/ru active
- 1972-05-31 AR AR242297A patent/AR198787A1/es active
- 1972-05-31 SE SE7207142A patent/SE387122B/xx unknown
- 1972-05-31 DK DK271972A patent/DK155328C/da not_active IP Right Cessation
- 1972-05-31 CS CS3759A patent/CS178409B2/cs unknown
- 1972-05-31 CA CA143,820A patent/CA1006875A/en not_active Expired
- 1972-06-01 JP JP5474472A patent/JPS5638594B1/ja active Pending
- 1972-06-01 NL NLAANVRAGE7207408,A patent/NL173405C/xx not_active IP Right Cessation
- 1972-06-01 CH CH813372A patent/CH580101A5/xx not_active IP Right Cessation
- 1972-06-01 GB GB2560572A patent/GB1391005A/en not_active Expired
- 1972-06-01 FR FR7219699A patent/FR2140154B1/fr not_active Expired
- 1972-06-01 BE BE784284A patent/BE784284A/xx not_active IP Right Cessation
- 1972-06-01 HU HUAE361A patent/HU169432B/hu unknown
-
1975
- 1975-03-24 PH PH16956A patent/PH11673A/en unknown
-
1978
- 1978-03-09 HK HK130/78A patent/HK13078A/xx unknown
- 1978-12-30 MY MY237/78A patent/MY7800237A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
NL173405C (nl) | 1984-01-16 |
CS178409B2 (cs) | 1977-09-15 |
SE387122B (sv) | 1976-08-30 |
CH580101A5 (cs) | 1976-09-30 |
AU4255472A (en) | 1973-11-29 |
DE2226340C2 (cs) | 1987-07-16 |
FR2140154B1 (cs) | 1976-04-16 |
IL39466A0 (en) | 1972-07-26 |
DE2226340A1 (de) | 1973-03-15 |
AR198787A1 (es) | 1974-07-24 |
FI54125C (fi) | 1978-10-10 |
FI54125B (fi) | 1978-06-30 |
DK155328C (da) | 1989-09-18 |
FR2140154A1 (cs) | 1973-01-12 |
SU463262A3 (ru) | 1975-03-05 |
MY7800237A (en) | 1978-12-31 |
DK155328B (da) | 1989-03-28 |
US3843681A (en) | 1974-10-22 |
CA1006875A (en) | 1977-03-15 |
HU169432B (cs) | 1976-11-28 |
ES403343A1 (es) | 1975-04-16 |
AU463079B2 (en) | 1975-07-17 |
BE784284A (fr) | 1972-12-01 |
JPS5638594B1 (cs) | 1981-09-08 |
HK13078A (en) | 1978-03-17 |
ZA723344B (en) | 1973-12-19 |
NL7207408A (cs) | 1972-12-05 |
PH11673A (en) | 1978-05-19 |
PH10625A (en) | 1977-07-21 |
GB1391005A (en) | 1975-04-16 |
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