SE330589B - - Google Patents

Info

Publication number
SE330589B
SE330589B SE381063A SE381063A SE330589B SE 330589 B SE330589 B SE 330589B SE 381063 A SE381063 A SE 381063A SE 381063 A SE381063 A SE 381063A SE 330589 B SE330589 B SE 330589B
Authority
SE
Sweden
Prior art keywords
coprogen
penicillium
desferricoprogen
iron
isolated
Prior art date
Application number
SE381063A
Inventor
E Gaeumann
E Vischer
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH418862A external-priority patent/CH437639A/en
Priority claimed from CH1354762A external-priority patent/CH466503A/en
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of SE330589B publication Critical patent/SE330589B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07GCOMPOUNDS OF UNKNOWN CONSTITUTION
    • C07G11/00Antibiotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02Iron compounds
    • C07F15/025Iron compounds without a metal-carbon linkage
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/02Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Coprogen and desferricoprogen are manufactured by growing Penicillium citrinum M 3614, Penicillium camemberti M 98, Penicillium urticae 4277, Penicillium notatum 1613 or Penicillium chrysogenum 4360 under aerobic conditions in an aqueous nutrient solution containing a carbon source and a nitrogen source and one or more inorganic salts. Coprogen and/or desferricoprogen are isolated from the culture filtrate and desferricoprogen may be converted to coprogen by addition of an iron salt, e.g. ferric chloride, or desferricoprogen may be obtained from coprogen by removing iron with an iron complex-forming substance, e.g. 8-hydroxyquinoline. The nutrient medium preferably contains less than 10-7 mol./litre of iron. The coprogen may be isolated by adsorption or by solvent extraction. Examples are given.
SE381063A 1962-04-05 1963-04-05 SE330589B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH418862A CH437639A (en) 1962-04-05 1962-04-05 Process for the production of coprogen and desferricoprogen
CH1354762A CH466503A (en) 1962-11-19 1962-11-19 Process for the production of coprogen and desferricoprogen

Publications (1)

Publication Number Publication Date
SE330589B true SE330589B (en) 1970-11-23

Family

ID=25694876

Family Applications (1)

Application Number Title Priority Date Filing Date
SE381063A SE330589B (en) 1962-04-05 1963-04-05

Country Status (4)

Country Link
DK (1) DK104508C (en)
FR (1) FR1355923A (en)
GB (1) GB1029999A (en)
SE (1) SE330589B (en)

Also Published As

Publication number Publication date
FR1355923A (en) 1964-03-20
DK104508C (en) 1966-05-31
GB1029999A (en) 1966-05-18

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