ES354475A1 - Improvements introduced in an antibiotic. (Machine-translation by Google Translate, not legally binding) - Google Patents

Improvements introduced in an antibiotic. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES354475A1
ES354475A1 ES354475A ES354475A ES354475A1 ES 354475 A1 ES354475 A1 ES 354475A1 ES 354475 A ES354475 A ES 354475A ES 354475 A ES354475 A ES 354475A ES 354475 A1 ES354475 A1 ES 354475A1
Authority
ES
Spain
Prior art keywords
atcc
antibiotic
broth
pyrollnitrin
translation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES354475A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES354475A1 publication Critical patent/ES354475A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

The antibiotic pyrollnitrin, also known as antibiotic A10338 (Specification 1,097,173), is prepared by cultivating a microorganism selected from Pseudomonas fluorescens ATCC 17810, ATCC 17416, ATCC 17417 or ATCC 17419 or Pseudomonas multivorans ATCC 17460, ATCC 17478, ATCC 17759 or ATCC 17760 in a culture medium containing assimilable sources of carbon, nitrogen and inorganic salts under submerged aerobic conditions until a substantial amount of the antibiotic is produced in the culture broth. The antibiotic may be recovered from the fermentation broth by diluting the broth with a water-miscible organic solvent such as methanol, filtering and extracting the clarified broth with a water-immiscible solvent such as chloroform. The antibiotic has antibacterial and antifungal properties and may be used in the treatment of mildew or anthracnose in plants. A pharmaceutical composition comprises pyrollnitrin and a carrier.
ES354475A 1967-08-10 1968-05-29 Improvements introduced in an antibiotic. (Machine-translation by Google Translate, not legally binding) Expired ES354475A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65960767A 1967-08-10 1967-08-10

Publications (1)

Publication Number Publication Date
ES354475A1 true ES354475A1 (en) 1970-02-16

Family

ID=24646050

Family Applications (1)

Application Number Title Priority Date Filing Date
ES354475A Expired ES354475A1 (en) 1967-08-10 1968-05-29 Improvements introduced in an antibiotic. (Machine-translation by Google Translate, not legally binding)

Country Status (8)

Country Link
BE (1) BE716547A (en)
CH (1) CH514673A (en)
DE (1) DE1767760A1 (en)
ES (1) ES354475A1 (en)
FR (1) FR1585053A (en)
GB (1) GB1225379A (en)
IL (1) IL30058A (en)
NL (1) NL6807679A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1314019A (en) * 1969-07-19 1973-04-18 Rolland Sa A Antibiotic substance and process for the extraction of such an antibiotic substance from a strain of pseudomonas
DE2860724D1 (en) * 1977-11-01 1981-08-27 Beecham Group Plc Pseudomonic acid c, pharmaceutically acceptable salts or esters thereof, processes for their preparation and pharmaceutical or veterinary compositions containing them
CA1115699A (en) * 1978-05-20 1982-01-05 Alan D. Curzons Lithium pseudomonate and its preparation
GB0814830D0 (en) 2008-08-13 2008-09-17 Univ Cardiff Antimicrobial agent and method for the production thereof

Also Published As

Publication number Publication date
BE716547A (en) 1968-12-16
FR1585053A (en) 1970-01-09
NL6807679A (en) 1969-02-12
IL30058A (en) 1972-09-28
GB1225379A (en) 1971-03-17
DE1767760A1 (en) 1971-07-01
IL30058A0 (en) 1968-07-25
CH514673A (en) 1971-10-31

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