SE0202613D0 - Förfarande och prob för identifiering av ämnen som modifierar bakteriers virulens, som sådana identifierade ämnen samt deras användning - Google Patents
Förfarande och prob för identifiering av ämnen som modifierar bakteriers virulens, som sådana identifierade ämnen samt deras användningInfo
- Publication number
- SE0202613D0 SE0202613D0 SE0202613A SE0202613A SE0202613D0 SE 0202613 D0 SE0202613 D0 SE 0202613D0 SE 0202613 A SE0202613 A SE 0202613A SE 0202613 A SE0202613 A SE 0202613A SE 0202613 D0 SE0202613 D0 SE 0202613D0
- Authority
- SE
- Sweden
- Prior art keywords
- substances
- bacteria
- virulence
- probes
- modify
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/14—Thiadiazoles; Hydrogenated thiadiazoles condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/64—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/72—Hydrazones
- C07C251/86—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/40—Y being a hydrogen or a carbon atom
- C07C323/42—Y being a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/88—Nicotinoylhydrazones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/24—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0202613A SE0202613D0 (sv) | 2002-09-04 | 2002-09-04 | Förfarande och prob för identifiering av ämnen som modifierar bakteriers virulens, som sådana identifierade ämnen samt deras användning |
AU2003256215A AU2003256215A1 (en) | 2002-09-04 | 2003-09-04 | Method and probe for identifying bacterial virulence modifying agents, agents thus identified, and their use |
EP03794402A EP1543148A1 (en) | 2002-09-04 | 2003-09-04 | Method and probe for identifying bacterial virulence modifying agents, agents thus identified, and their use |
PCT/SE2003/001381 WO2004022775A1 (en) | 2002-09-04 | 2003-09-04 | Method and probe for identifying bacterial virulence modifying agents, agents thus identified, and their use |
US10/526,461 US7351861B2 (en) | 2002-09-04 | 2003-09-04 | Method and probe for identifying bacterial virulence modifying agents, agents thus identified, and their use |
EP10161123A EP2210597A3 (en) | 2002-09-04 | 2003-09-04 | Bacterial virulence modifying agents |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0202613A SE0202613D0 (sv) | 2002-09-04 | 2002-09-04 | Förfarande och prob för identifiering av ämnen som modifierar bakteriers virulens, som sådana identifierade ämnen samt deras användning |
Publications (1)
Publication Number | Publication Date |
---|---|
SE0202613D0 true SE0202613D0 (sv) | 2002-09-04 |
Family
ID=20288889
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE0202613A SE0202613D0 (sv) | 2002-09-04 | 2002-09-04 | Förfarande och prob för identifiering av ämnen som modifierar bakteriers virulens, som sådana identifierade ämnen samt deras användning |
Country Status (5)
Country | Link |
---|---|
US (1) | US7351861B2 (sv) |
EP (2) | EP1543148A1 (sv) |
AU (1) | AU2003256215A1 (sv) |
SE (1) | SE0202613D0 (sv) |
WO (1) | WO2004022775A1 (sv) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0202613D0 (sv) * | 2002-09-04 | 2002-09-04 | Innate Pharmaceuticals Ab | Förfarande och prob för identifiering av ämnen som modifierar bakteriers virulens, som sådana identifierade ämnen samt deras användning |
WO2006083266A1 (en) * | 2004-05-07 | 2006-08-10 | Janssen Pharmaceutica, N.V. | Inhibitors of bacterial type iii protein secretion systems |
US20050282824A1 (en) * | 2004-05-07 | 2005-12-22 | Xiaobing Li | Substituted pyrimidines as inhibitors of bacterial type III protein secretion systems |
JP2008540487A (ja) * | 2005-05-11 | 2008-11-20 | ノボ ノルディスク アクティーゼルスカブ | 肥満症の治療に有用な新規ハロアルキルスルホン置換化合物 |
WO2006132583A1 (en) * | 2005-06-07 | 2006-12-14 | Innate Pharmaceuticals Ab | Method and means for preventing and inhibiting respiratory disease, atherosclerosis and osteoporosis caused by chlamydia pneumoniae infection |
GB2429283B8 (en) * | 2006-08-01 | 2013-04-10 | Univ Hertfordshire Higher Education Corp | Preservative efficacy testing |
ATE486283T1 (de) * | 2006-08-14 | 2010-11-15 | Biocontrol Systems Inc | Verfahren zur erkennung von listerien |
WO2009145829A1 (en) | 2008-04-01 | 2009-12-03 | University Of Massachusetts | Type iii secretion inhibitors, analogs and uses thereof |
CN105566147B (zh) | 2015-12-07 | 2018-03-09 | 北京信德润兴科技有限公司 | 一种化合物及其制备方法和用途及相应的靶向给药系统和化疗药物 |
WO2018232298A1 (en) * | 2017-06-16 | 2018-12-20 | The Research Foundation For The State University Of New York | Anti-fungals compounds targeting the synthesis of fungal sphingolipids |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU173047B (hu) * | 1975-03-20 | 1979-02-28 | Chinoin Gyogyszer Es Vegyeszet | Sposob poluchenija novykh salicilanilidov |
FR2336931A1 (fr) * | 1975-12-30 | 1977-07-29 | Dick Pierre | Compositions anthelminthiques a base de benzimidazoles |
SU1226807A1 (ru) | 1984-10-10 | 1992-05-07 | Ивановский сельскохозяйственный институт | Способ получени 2-ацетокси-4 @ -хлор-3,5-дийодбензанилида |
SU1685935A1 (ru) | 1989-12-21 | 1991-10-23 | Институт медицинской паразитологии и тропической медицины им.Е.И.Марциновского | 2-[(Бензо-2,1,3-тиадиазол-4-сульфонил)амино] бензойные кислоты в качестве промежуточных продуктов в синтезе N-(4-хлорфенил)- или N-(3,4-дихлорфенил)-2-[(бензо-2,1,3-тиадиазол-4-сульфонил)амино]-5-хлорбензамида, обладающих антигельминтной активностью |
SU1715357A1 (ru) * | 1990-04-09 | 1992-02-28 | Ивановский сельскохозяйственный институт | Способ лечени фасциолеза и мониезиоза овец |
US6180604B1 (en) | 1996-08-21 | 2001-01-30 | Micrologix Biotech Inc. | Compositions and methods for treating infections using analogues of indolicidin |
WO1999011262A1 (en) * | 1997-09-02 | 1999-03-11 | Roche Diagnostics Gmbh | Mpl-receptor ligands, process for their preparation, medicaments containing them and their use for the treatment and prevention of thrombocytopaenia and anaemia |
US6136542A (en) * | 1998-05-13 | 2000-10-24 | Institut Pasteur | Method for screening for inhibitors and activators of type III secretion machinery in gram-negative bacteria |
US6136541A (en) * | 1999-02-22 | 2000-10-24 | Vialogy Corporation | Method and apparatus for analyzing hybridized biochip patterns using resonance interactions employing quantum expressor functions |
GB2365426A (en) * | 2000-08-01 | 2002-02-20 | Pantherix Ltd | Bactericidal benzamide derivatives |
US6846933B1 (en) * | 2000-10-30 | 2005-01-25 | The Board Of Trustees Of Wellesley College | Antimycobacterial compounds and method for making the same |
US20040110963A1 (en) | 2001-01-22 | 2004-06-10 | Kaspar Burri | Novel hydrazones |
SE0202613D0 (sv) * | 2002-09-04 | 2002-09-04 | Innate Pharmaceuticals Ab | Förfarande och prob för identifiering av ämnen som modifierar bakteriers virulens, som sådana identifierade ämnen samt deras användning |
-
2002
- 2002-09-04 SE SE0202613A patent/SE0202613D0/sv unknown
-
2003
- 2003-09-04 EP EP03794402A patent/EP1543148A1/en not_active Withdrawn
- 2003-09-04 AU AU2003256215A patent/AU2003256215A1/en not_active Abandoned
- 2003-09-04 WO PCT/SE2003/001381 patent/WO2004022775A1/en not_active Application Discontinuation
- 2003-09-04 EP EP10161123A patent/EP2210597A3/en not_active Withdrawn
- 2003-09-04 US US10/526,461 patent/US7351861B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US7351861B2 (en) | 2008-04-01 |
WO2004022775A8 (en) | 2005-05-12 |
EP1543148A1 (en) | 2005-06-22 |
EP2210597A2 (en) | 2010-07-28 |
EP2210597A3 (en) | 2011-01-12 |
US20060134724A1 (en) | 2006-06-22 |
AU2003256215A1 (en) | 2004-03-29 |
WO2004022775A1 (en) | 2004-03-18 |
AU2003256215A8 (en) | 2004-03-29 |
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