SE0004217L - Förfarande för framställning av mikropartiklar - Google Patents
Förfarande för framställning av mikropartiklarInfo
- Publication number
- SE0004217L SE0004217L SE0004217A SE0004217A SE0004217L SE 0004217 L SE0004217 L SE 0004217L SE 0004217 A SE0004217 A SE 0004217A SE 0004217 A SE0004217 A SE 0004217A SE 0004217 L SE0004217 L SE 0004217L
- Authority
- SE
- Sweden
- Prior art keywords
- microparticles
- solution
- mixing
- active substance
- starch
- Prior art date
Links
- 239000011859 microparticle Substances 0.000 title abstract 6
- 238000002360 preparation method Methods 0.000 title abstract 3
- 229920002472 Starch Polymers 0.000 abstract 4
- 239000000243 solution Substances 0.000 abstract 4
- 235000019698 starch Nutrition 0.000 abstract 4
- 239000008107 starch Substances 0.000 abstract 4
- 239000002202 Polyethylene glycol Substances 0.000 abstract 3
- 239000007864 aqueous solution Substances 0.000 abstract 3
- 229920002988 biodegradable polymer Polymers 0.000 abstract 3
- 239000004621 biodegradable polymer Substances 0.000 abstract 3
- 229920001223 polyethylene glycol Polymers 0.000 abstract 3
- 239000013543 active substance Substances 0.000 abstract 2
- 229940088623 biologically active substance Drugs 0.000 abstract 2
- 239000003960 organic solvent Substances 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 229920000249 biocompatible polymer Polymers 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 239000008384 inner phase Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008385 outer phase Substances 0.000 abstract 1
- 239000012071 phase Substances 0.000 abstract 1
- 238000007711 solidification Methods 0.000 abstract 1
- 230000008023 solidification Effects 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
- Y10T428/2985—Solid-walled microcapsule from synthetic polymer
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0004217A SE518007C2 (sv) | 2000-11-16 | 2000-11-16 | Förfarande för framställning av mikropartiklar |
| US09/970,796 US6616949B2 (en) | 2000-11-16 | 2001-10-05 | Process for producing microparticles |
| EP01972894A EP1333815A1 (en) | 2000-11-16 | 2001-10-05 | Process for producing microparticles |
| CA002429103A CA2429103A1 (en) | 2000-11-16 | 2001-10-05 | Process for producing microparticles |
| PCT/SE2001/002167 WO2002039986A1 (en) | 2000-11-16 | 2001-10-05 | Process for producing microparticles |
| AU2001292528A AU2001292528A1 (en) | 2000-11-16 | 2001-10-05 | Process for producing microparticles |
| JP2002542361A JP2004513706A (ja) | 2000-11-16 | 2001-10-05 | 微粒子の製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0004217A SE518007C2 (sv) | 2000-11-16 | 2000-11-16 | Förfarande för framställning av mikropartiklar |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE0004217D0 SE0004217D0 (sv) | 2000-11-16 |
| SE0004217L true SE0004217L (sv) | 2002-05-17 |
| SE518007C2 SE518007C2 (sv) | 2002-08-13 |
Family
ID=20281863
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE0004217A SE518007C2 (sv) | 2000-11-16 | 2000-11-16 | Förfarande för framställning av mikropartiklar |
Country Status (2)
| Country | Link |
|---|---|
| US (1) | US6616949B2 (xx) |
| SE (1) | SE518007C2 (xx) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE518008C2 (sv) * | 2000-11-16 | 2002-08-13 | Bioglan Ab | Parenteralt administrerbara mikropartiklar och förfarande för framställning av desamma |
| US20050142205A1 (en) * | 2003-07-18 | 2005-06-30 | Julia Rashba-Step | Methods for encapsulating small spherical particles prepared by controlled phase separation |
| US8075919B2 (en) * | 2003-07-18 | 2011-12-13 | Baxter International Inc. | Methods for fabrication, uses and compositions of small spherical particles prepared by controlled phase separation |
| JP2007508240A (ja) * | 2003-07-22 | 2007-04-05 | バクスター・インターナショナル・インコーポレイテッド | 低分子量有機分子の小球状粒子ならびにその調製方法および使用方法 |
| ES2313350T3 (es) * | 2004-05-12 | 2009-03-01 | Baxter International Inc. | Microesferas de acido nucleico, produccion y suministro de las mismas. |
| AU2005244840C1 (en) * | 2004-05-12 | 2012-05-10 | Baxter Healthcare S.A. | Microspheres comprising protein and showing injectability at high concentrations of said agent |
| WO2005112885A2 (en) * | 2004-05-12 | 2005-12-01 | Baxter International Inc. | Oligonucleotide-containing microspheres, their use for the manufacture of a medicament for treating diabetes type 1 |
| US8728525B2 (en) | 2004-05-12 | 2014-05-20 | Baxter International Inc. | Protein microspheres retaining pharmacokinetic and pharmacodynamic properties |
| US7315758B2 (en) * | 2004-06-03 | 2008-01-01 | Lynntech, Inc. | Transdermal delivery of therapeutic agent |
| US20060228734A1 (en) * | 2005-03-18 | 2006-10-12 | Applera Corporation | Fluid processing device with captured reagent beads |
| AU2007281737B2 (en) | 2006-08-04 | 2013-09-19 | Baxter Healthcare S.A. | Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes |
| JP5744513B2 (ja) * | 2007-04-17 | 2015-07-08 | バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated | 肺送達のための核酸微小粒子 |
| KR100871988B1 (ko) | 2007-06-25 | 2008-12-05 | 한국과학기술원 | 수용성 용매 없이 수용성 거대분자 약물이 봉입된 생분해성미립구 담체의 제조방법 및 생분해성 미립구 담체 |
| US8323615B2 (en) | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing multi-phasic dispersions |
| US8367427B2 (en) | 2008-08-20 | 2013-02-05 | Baxter International Inc. | Methods of processing compositions containing microparticles |
| US8323685B2 (en) | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing compositions containing microparticles |
| MX342259B (es) | 2010-10-29 | 2016-09-22 | Buckman Laboratories Int Inc | Fabricacion de papel y productos hechos por medio de la misma con microparticulas polimericas reticuladas ionicas. |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE744162A (fr) | 1969-01-16 | 1970-06-15 | Fuji Photo Film Co Ltd | Procede d'encapsulage |
| US3881991A (en) | 1969-01-24 | 1975-05-06 | Hayashibara Co | Process for producing amylose powders having a mean degree of polymerization between 20{14 30 |
| DE2010115A1 (de) | 1970-03-04 | 1971-09-16 | Farbenfabriken Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung von Mikrogranulaten |
| US4389330A (en) | 1980-10-06 | 1983-06-21 | Stolle Research And Development Corporation | Microencapsulation process |
| US4713249A (en) | 1981-11-12 | 1987-12-15 | Schroeder Ulf | Crystallized carbohydrate matrix for biologically active substances, a process of preparing said matrix, and the use thereof |
| SE459005B (sv) | 1985-07-12 | 1989-05-29 | Aake Rikard Lindahl | Saett att framstaella sfaeriska polymerpartiklar |
| GB2209937B (en) | 1987-09-21 | 1991-07-03 | Depiopharm S A | Water insoluble polypeptides |
| JP2670680B2 (ja) | 1988-02-24 | 1997-10-29 | 株式会社ビーエムジー | 生理活性物質含有ポリ乳酸系微小球およびその製造法 |
| US5019400A (en) | 1989-05-01 | 1991-05-28 | Enzytech, Inc. | Very low temperature casting of controlled release microspheres |
| WO1990013361A1 (en) | 1989-05-04 | 1990-11-15 | Southern Research Institute | Improved encapsulation process and products therefrom |
| DK168790D0 (xx) | 1990-07-13 | 1990-07-13 | Novo Nordisk As | |
| ATE154241T1 (de) | 1991-10-01 | 1997-06-15 | Takeda Chemical Industries Ltd | Mikropartikeln-zusammenfassung zur verlängerten freigabe und herstellung derselbe |
| WO1993015722A1 (en) | 1992-02-07 | 1993-08-19 | Syntex (Usa) Inc. | Controlled delivery of pharmaceuticals from preformed porous microparticles |
| WO1993021008A1 (en) | 1992-04-20 | 1993-10-28 | Redding Bruce K Jr | Method and apparatus for the modification of starch and other polymers |
| AU670168B2 (en) | 1992-12-02 | 1996-07-04 | Alkermes Controlled Therapeutics, Inc. | Controlled release growth hormone containing microspheres |
| US5578709A (en) | 1993-03-09 | 1996-11-26 | Middlesex Sciences, Inc. | Macromolecular microparticles and methods of production |
| US5981719A (en) | 1993-03-09 | 1999-11-09 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
| DE4434877A1 (de) | 1994-09-29 | 1996-04-04 | Fresenius Ag | Verfahren zur Herstellung von Stärkeabbauprodukten |
| KR100201352B1 (ko) | 1995-03-16 | 1999-06-15 | 성재갑 | 단일주사 백신 제형 |
| SE505146C2 (sv) | 1995-10-19 | 1997-06-30 | Biogram Ab | Partiklar för fördröjd frisättning |
| US5959102A (en) | 1997-06-30 | 1999-09-28 | Rutgers University | Starch purification by thermally tolerant broad pH range proteolytic enzymes |
| SE512663C2 (sv) | 1997-10-23 | 2000-04-17 | Biogram Ab | Inkapslingsförfarande för aktiv substans i en bionedbrytbar polymer |
| JPH11302156A (ja) * | 1998-04-16 | 1999-11-02 | Tanabe Seiyaku Co Ltd | ポリペプチドの微粒子化方法 |
-
2000
- 2000-11-16 SE SE0004217A patent/SE518007C2/sv not_active IP Right Cessation
-
2001
- 2001-10-05 US US09/970,796 patent/US6616949B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| SE0004217D0 (sv) | 2000-11-16 |
| SE518007C2 (sv) | 2002-08-13 |
| US20020086060A1 (en) | 2002-07-04 |
| US6616949B2 (en) | 2003-09-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |