SA96160591B1 - SILICONE COMPOSITIONS - Google Patents

Abstract

Abstract: The invention relates to a flavoring, scented, coolant or antimicrobial composition comprising an aminoalkylsilicone with an aminosiloxane content of about 0.1% to 2% on a repeat unit basis. The formulation provides improved survival, antimicrobial effect and/or efficacy on the surface. 19

Description

Y silicone Silicone fittings Full description! 0 BACKGROUND: silicone-containing compositions The present invention relates to silicone-containing compositions and their use in various household products such as personal care products, household cleaners, etc. In particular; The invention relates to silicone-containing lipophilic compositions with silicone-containing lipophilic compositions based on flavoring, scenting, coolant or antimicrobial agents as lipophilic and which exhibit persistence; Effect and/or effectiveness of improvers on surfaces treated with Baha eg ; tooth surfaces; false teeth; Skin; the poet; the laundry; utensils; material processing etc. In addition to this, the invention relates to silicone-containing bleaching compositions which in addition to this contain silicone-containing bleaching compositions 0 sensitive to bleach such as fragrances and flavors; etc.”, which show improved stability. General description of the invention The lipophilic formulations are like flavor formulations; Perfume 83 and disinfectant commonly used either directly or in a variety of household products, including cosmetic formulations; intestinal and dental prostheses; laundry detergent and hard surface cleaning products; utensils; ovary; Etc.. The problem is 1

Cede A common problem with lipophilic formulations is to improve the presence and survival of the lipophilic component (!

CE surface. It is desirable in many - if not most - household applications to reinforce the liposome on the surface in order to; For example; Providing an increased flavor or fragrance effect or an increased antimicrobial activity. Modern dental and dental preparations and dentures are hygienic; For example; Typically, Y. Jol se as well as cantitartar and/or antiplaque contain anti-plaque agents by antimicrobial plaque and flavourings. The antimicrobial action may affect plaque formation either by reducing the number of bacteria in the mouth/dental dentures or by killing these bacteria trapped in the mouth/dentals or by killing these bacteria trapped in the membrane to prevent additional growth and metabolism. Flavorings may reduce bad breath by acting as a deodorant. may vo

Yay v also as a breathalyzer. It remains on the surface of the teeth or artificial teeth, where plaque is formed La pad industrial; A traditional drawback of dental preparations is that they only last for a relatively short period of time during which they are antimicrobial in the preparations. Jal go brushing teeth or rinsing the mouth; Be available for effect 0 The problem is complicated by the infrequent use of dental cleaning products; Mostly they are used once; Maybe twice daily. Accordingly, a long period of time between brushings is ideal. Plaque for most people provides the conditions for plaque formation on the surface. pe in many other personal and domestic applications; It is desirable to provide staying power; laundry detergent will benefit; For example; In order to increase the retention of fragrance on the fabrics in order to provide an increased fragrance effect on the fabric after washing or during use. Plus Antimicrobial Stay is also beneficial from the point of view of reducing unpleasant odors associated with sweat and other dirt. In pure fragrances and scented cosmetics. Led persistence will also be Tix Fragrance persistence on the other hand will be useful in cough/cold products. ak Syd is an agent which has persistence; effect and/or lipophilic effect thereof; There is a need to develop lipophilic formulations. Antimicrobial surface enhancer. Fragrances; Flavorings; etc. » in formulations that contain Ra, and the use of lipophilic compounds also has a number of problems, especially the loss of the characteristic or intensity of the fragrance or the laying may bleach 0 ; It may also be bleaching the flavor as a result of a cross-reaction with the bleach. The effect of the bleaching agent; harmful. It is therefore desirable to improve the stability and efficacy of bleaching formulations containing sensitive ingredients. © Known in dental cleaning formulations; On the pretext of coating the teeth with silicones, the inclusion of silicones in a mouthwash containing GB-A-689,679 prevents tooth decay and stains. For example, “reveal” to prevent sticking; or remove tar; Stains; organopolysiloxane on organic polysiloxane and food residue from teeth. May include lotion mouth antiseptic compounds; Such as thymol, tartar, tartar vo: and flavoring and fragrant agents.

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¢ US Patent No. 78605814 discloses dental preparations that include; In combination with a higher aliphatic acyl amide or an amino carboxylic acid aes compound as the active substance and a silicone compound 81116006. The patent notes that silicone compounds have been proposed to prevent adhesion or to facilitate the removal of tar” stains; Tartir 8:188; etc. of the teeth. It is reported that the silicone compound acts as an adjunct to the active ingredient in improving the antimicrobial and acid-inhibiting activity. Dimethyl polysiloxanes are reported to be particularly effective. Flavoring oils and/or menthol may be added. J sie. US Patent No. 174171 discloses quaternary ammonium salts of siloxane polymers 60 for use as cationic surfactants. Bactericidal and anti-cavity agents. Accordingly, the present invention provides a flavor combination; antimicrobial ph perfume or other surface-based lipophilic substance; Enhanced effect and/or efficacy. The invention also provides a gape composition comprising an inorganic persalt bleaching agent | and a lipophilic compound, Jie lipophilic, a flavoring and/or fragrance with improved stability. 0: According to one of the inventions; Flavor combination available; fragrance de antimicrobial or other substance 0 : lipophilic containing aminoalkylsilicone having an aminoalkylsiloxane content of about 1 to 77 on a repeat unit basis. ; Y. The invention also relates to the use of an aminoalkylsilicone with a selected lipophile of flavoring agents; physiological clip perfumery; antimicrobial and mixtures thereof to provide survival (panda) on the surface; selecting aminoalkylsilicone from aminoalkylsilicones having an aminoalkylsiloxane content of approximately 70.1 to 77 on a tactase unit basis. Depending on an additional aspect of the invention; a bleaching composition is available Includes inorganic persalt bleaching agent lipophile selected flavoring agents fragrances physiological coolants antimicrobial and in yay blends

0° aminoalkylsilicone s has an aminoalkylsiloxane content of about 1 to yy on a repeat unit basis. The invention relates to the use of an aminoalkylsilicone with an inorganic persalt bleaching agent and a selected lipophile from a variety of flavoring agents; perfumes; Spa Physiological; antimicrobial and blends thereof to provide enhanced lipophilic stability; He selects an aminoalkylsilicone from aminoalkylsilicones with an aminoalkylsiloxane content of about 1 to ?# on the basis of exact frequency. All percentages and percentages herein are by weight of the total formulation; Unless stated otherwise. Thereby, the composition of the invention includes an aminoalkylsilicone plaque anti-plaque agent and a lipophile-0 selected from the flavoring agents; perfumes; physiological coolants; Antimicrobial z and mixtures thereof. Other formulations of the invention take the form of bleaching and/or detergent formulations which comprise an aminoalkylsilicone plaque anti-plaque agent and a lipophilic substance (Jipophile) in general; La aminoalkylsilicone is a hydrophobic, noncyclic aminoalkylsilicone that has a formula that includes two base units: m (1) and m (0) (.510) where m + 8 is 1 or 1 or “8 is 1 or ? or osmY is yellow 00 7; and (7) #draw510m(0(0),02 where – + 5 is 1 or 7 or ¥ and and 5 are integers; where RI and 82 are each separately selected from an alkyl GSH and an alkenyl from about 1 to 200 about 0 carbon atoms optionally substituted with a fluoro, cyano, or /© hydroxy group chydroxy, calkoxy, and cacetoxy, for example.”, where RI and 2H each separately are selected from methyl emethyl ethyl phenyl phenyl trifluoro-propyl propyl and ccyanopropyl where R is R a R Rs XJ SE lL where 183 is the divalent alkylene of about Yom) preferably about ?- vo © carbon atom optionally substituted or optionally intersected by ©0 atoms; 84 RES RS which may be the same or different and selected from GH an alkyl of about Yom) preferably about -1 Yay

1 a 0 is most preferably about a 1-; carbon atom optionally substituted or crossed by N and/or 0 atoms; Xs is a monovalent anion, Jie monovalent anion, halide, chydroxide, and ctosylate and includes the aforementioned aminoalkylsilicone of about .77-8 preferably of about .57-77 of unit (1) On a repeating unit basis In a preferred embodiment; seedlings of aminoalkylsilicones on .amodimethicones Amodimethicones are polydimethylsiloxane polymers containing .aminoalkyl groups Aminoalkyl groups may be present either dangling or at one or more ends of the .polydimethylsiloxane chain | preferably aminoalkylsilicones in which the aminoalkyl R ' part is mutated from «(CH,);N(CH,CH,OH), «(CH,);NHCH,CH,NH, “(CH,);NH, 00 Ra “(CHp)3N(CH3)o(C3H37) X05” (CHp)NH5 and especially the (CH)3NH, (CH,);NHCH) ,CH,NH, 5 Aminoalkylsilicones with an average molecular weight of about 0006 and more are also preferred; preferably from about 0800 © to about 100001 preferably more than about 05 to approx. Aminoalkylsilicone compounds form Appropriate for use here and well known 0 Methods for preparing caminoalkylsilicones are given for example; in US Patent No. 14 examples of amodimethicones include LOST's Magnasoft Fluid These polymers include Je polymers aminoalkyl groups 448 Mostly to build polydimethylsiloxane. The typical construction for Magnasoft aminoalkyl de seas-containing units is: z / -0Si(Me)C3H{NHCH,CH,NH,. Y. © ; Aminoalkylsilicone is generally found at a level of about 0.501 to about 0765 preferably from about 70.1 to about 6 preferably from about 70.8 to about 21.9 by weight. 0 The composition of the invention Und preferably includes the lipophilic cine compound in general; The lipophilic compounds suitable for use herein are oil-like substances which are soluble or soluble in aminoalkylsilicone preferably at a level of at least about 1 preferably over 0 at least about 70 by weight at 0 LOY Preferred lipophilic compounds are selected from flavoring agents; perfumes; Jal go has physiological cooling and antimicrobial compounds. aminoalkylsilicone is working on i! ‎Y4Y z

to enhance the presence of the lipophilic compound on its lade surface; In doing so it provides a trace of flavor; Enhanced perfume or refrigerant' and/or persistence and/or antimicrobial effect. 0 Lipophilic flvorants suitable for use herein include one or more of the selected ingredients wintergreen oil oregano oil 0 bay leaf oil cbay leaf oil peppermint oil (Cy) spearmint oil clove oil sage oil 8886 sassafras oil lemon oil demon oil orange oil corange oil star anise oil canise oil benzaldehyde benzaldehyde myrrh pine oil obitter almond 0il camphor oil ccedar leaf oil marjoram oil amarjoram oil citronella oil ccitronella lavender oil ddavendar oil castor oil amustard oil peach oil pine needle oil pine needle oil rosemary oil thyme oil thyme oil cinnamon leaf oil ccinnamon leaf oil and mixtures thereof. lipophilic perfumes are suitable for use here on one or more known perfume ingredients including natural products Jie essential oils; resins; pure perfumes; 10, etc.. and jhe industrial components such as hydrocarbons, chydrocarbons, alcohols, aldehydes, ketones, ethers, cethers, acids, acids, esters, cesters: acetals, ketals nitriles, etc.” includes saturated and unsaturated compounds; Examples of aromatics suitable for use here include: | / geranyl acetate, linalyl acetate, citronellyl acetate, dihydromyrcenyl acetate, terpinyl 0 ' acetate, tricyclo decenyl acetate, tricyclodecenyl propioniate, 2-phenylethyl acetate, benzyl acetate, benzyl salicylate, benzyl benzoate, sytrallyl acetate, amyl salicylate, methyl dihydrojasmonate, phenoxyethyl isobutyrate, neryl acetate, trichloromethyl-phenylcarbinyl acetate, p -tertiary butyl-cyclohexyl acetate, isononyl acetate, cedryl acetate, vetiveryl acetate, benzylalcohol, 2-phenyl ethanol, linalool, tetra hydro Yo : linalool, citronellol, dimethylbenzylcarbinol, dihydromyrecenol, tetrahydromyrcenol, terpineol, eugenol, geraniol, vetiverol, 3-isocamphyl- Yay

z cyclohexanol,2-methyl-3-(p-tertiary butylphenyl)-propanol,2-methyl-3-(p-isopropylphenyl)-propanol,3-(p-tertiary butylphenyl)-propanol, nerol, alpha-n - amylcinnamic aldehyde, alpha-hexyl-cinnamic aldehyde, 4-(4-hydroxy-4- methylpentyl)-3-cyclohexenecarbaldehyde, 4-(4-methyl-3-pentenyl)-3- : cyclohexenecarbaldehyde, 4-acetoxy-3- pentyl-tetrahydropyran, 2-n-heptyl- 0 z cyclopentanone, 3-methyl-2-pentyl-cyclopentanone, n-decanal, n-dodecanal, hydroxycitronellal, phenylacetaldehyde dimethyl acetal, phenylacetaldehyde diethyl - acetal, geranotrile, citronellonitrile, cedryl methyl ether, isolongifolanone, aubepine nitrile, aubepine, heliotropine, coumarin, vanillin, diphenyl oxide, esters ionones, methyl ionones, isomethyl jonones, irones, cis-3-hexenol, and esters x of which indane musks, tetralin musks, isochroman musks, macrocyclic ketones, macrolactone musks, ethylene brassylate, aromatic nitromusks, and mixtures thereof. Suitable for use here lipophilic antimicrobial lipophilic antimicrobial compounds Vo “phenol” phenol “4-hexylresorcinol” riclosan “menthol” cthymol contains thymol “butyl paraben benzoyl peroxide” benzoic acid benzoic acid ceucalyptol from it. alhals ¢ salicylamides “propyl paraben “methyl paraben 1 / | Suitable for use here physiological cooling agent It includes a physiological cooling agent. Lie and mixtures of cmenthane ethers s menthane esters “carboxamides 0 are suitable for use here with the formula: menthane ethers choose: X ORs 0 optionally substituted with a hydroxy aliphatic radical It is an aliphatic radical Ry where ! 0 carbon atoms” preferably even Yo da containing optionally hydroxy substituted

Yay

4 carbon; and where X is hydrogen or hydroxy chydroxy as available “commercially under the generic name “Takasago” from Takasago International Corporation. A particularly preferred cooling agent for use in the formulations of the present invention is [3]. -1-menthoxy propan-1,2-diol (MPD)] Takasage 0 MPD is a monoglycerin derivative of 1-menthol that has excellent cooling activity. The most beneficial carboxamides are described in US Patent No. carrey issued January 77, 19979 to Wason et al.; and US Patent No. c£YY TAA issued YA October 1988 to Rawsell et al. Generally the level of the lipophilic compound in the formulations of the invention ranges from about 0 to 10.010 to about 000 preferably from about 70.06 to about 758 preferably more than about 70.1 to Jes by weight. The compositions of the invention optionally include one or more surfactants which are specially preferred in the lipophilic formulations of the invention for the purpose of dissolving the lipophile and for providing improved efficacy. Suitable servactins include organic industrial detergents 1. Non-soap non-soap anionic nonionic cationic zwitterionic and amphoteric 06. Many of these appropriate factors are disclosed in US Patent No. 4,051,774; Issued YV Sept 15977 to Gieske et al. : | Examples of servactins suitable for use herein include alkyl sulfates y-m and alkyl ether sulfates oxidized with from z/ve of about ro to about 10 mole of ethylene oxide. per gram molecule; Anionic sulfonates include linear alkyl benzene sulfonates primary or secondary alkane sulfonates “alkyl ester sulfonates”; Cg-Cy 4 olefin sulfonates alkyl glycerol sulfonates sulfonated polycarboxylic acids cfatty acyl glycerol sulfonates and mixtures thereof; anionic carboxylates vo including primary and tertiary alkyl carboxylate Cg to ethoxy carboxylate Cg polyethoxy polycarboxylate surfactants with an average degree of ethoxylation from about zero to about 10; C5-C,; sarcosinates such as sodium cocoylsarcosinate Yay:

. 1 ] Hamposyl-95) sodium lauroyl sarcosinate from (W.

R.

Grace thickening products ethylene J propylene oxide with fatty acids 1800 efatty alcohols fatty amides OA) polyhydric alcohols “fatty amides” (sorbitan oleate <sorbitan monostearate alkyl phenols (e.g. polypropyleneoxide 5 (Tergitol 0) or polyoxybutylene e.g. ¢ (Pluronics) alkylpolysaccharides as listed in US Patent No. sweety amine oxides such as dimethyl lauryl amine oxide “dimethyl cocamine oxide : Tween 80 s Tween 40 is polysorbates ¢ (Aromox) cocoalkyldimethyl amine oxide s cationic surfactants ¢x— “sorbitan monooleate ¢ sorbitan stearates ¢ (Hercules) | such as “cetyl trimethyl ammonium bromide” cetyl pyridinium chloride 0 : di-isobutyl phenoxy ethoxy ethyl-dimethyl benzyl ammonium chloride A .coconut alkyl trimethyl ammonium nitrate 5 It is highly preferred here in terms of lipophilic solubility of the non-ionic surfactant.One of the non-ionic surfactants suitable for use here has The general formula is : R—(OCHCH,)z—(OCH,CH,)7—OH z Vo but z in which Ry is an alk(en)yl group or alk(en)yl phenyl group It has A to YY preferably 01 A to Ye a carbon atom in the alk(en)yl part and represents 8 and 2 weight averages within the range: 0 A = 5 Av hia on respectively. Alkyl groups with shorter chain length are generally avoided because of their effectiveness and because the unreacted fatty alcohol in these ©-servactenes is a source of unpleasant odor and sometimes skin irritation. We will understand that servactins of this type are usually mixtures of various degrees of sethoxylation/propoxylation and according to this nym Jia weight averages assigned to the number of .ethoxylate 5 propoxylate groups include non-ionic servactins of the above general type alkoxylates mixed in m: and “both are within the limits of about 1 to about Ae, and it is preferable that Gm be within limits of about 1.” to about 01, preferably more than about ? to about 01 preferably within the limits of z about JY about Te preferably more than about © to about 50. One of these materials is 0 Yay

. 11 PPG-5-ceteth-20 (available from Croda Inc. as nym Cua ((Procetyl AWS) have values 0 : Yo, respectively. Other suitable non-ionic servactins include polyoxygenated servactins; Wie Z octyl- and nonylphenol ethers La gad (ethoxylated alkylphenol ethers) contain (EO 11-4) Cg-Chy alcohols ethoxylated aliphatic monomers which 0 may be linear or branched and containing VTA preferably 10-1 BO and ethoxylated hydrogenated castor oils. Generally, the ratio of surfactant to aromatic AD or other oily substance will range from z | about 1: 00 to approximately 1:100; preferably from approximately 0:01 to approximately XY more preferably from approximately 0 ° to approximately .:1V Ve also includes bleaching compositions aud of The invention is one or more: bleaching agents optionally with sources of organic peroxyacid corganic peroxyacid precursors mice generating materials chelating agents etc. aah bleaching agent bleaching agent inorganic perineal salt form inorganic persalt and can be selected from any well known bleaching agents of Z 1 for use in household bleaching; detergents; denture cleaners; etc.. such as alkali metal and perborates < ammonium persulfates including “mono-and tetrahydrates” percarbones (optionally encapsulated as described in GB-A-1,466,799), perphosphates and metal; Alkaline earth metal peroxides s alkali metal Examples of suitable bleaching agents include potassium persulfates spotassium cammonium sodium and lithium: 1 sodium pyrophosphate peroxyhydrate «perborate mono- and tetrahydrates s lithium | 0 And magnesium, calcium and zinc peroxides «calcium 00?. Of this, however, it is preferable to use percarbonates 85 persulfates (alkali metal persulfates) and finish mixtures, preferably more percarbonates 5 perborates alkali metal. alkali metal | : vo The amount of bleaching agent in the bleaching formulations of the invention is generally from about © to about Z 0 0 preferably from about 01 to about J% 0 0 Yay

11 Which in effervescence generator bleaching formulations may also include a fouling agent preferred embodiments takes the form of a solid base material which in the presence of water emits carbon dioxide or oxygen 0 with furan. The fizzing agent can be selected from carbon dioxide generators that are effective under acidic pH conditions; neutral or alkaline; However, it is preferably a combination of a generative agent that is more or less effective under acidic or neutral pH conditions and a generic agent that is more or less effective under alkaline pH conditions. Furans that are effective under acidic or neutral pH conditions include a combination of at least one alkali metal carbonate or bicarbonate, sodium carbonate, or sodium bicarbonate. Sodium bicarbonate Jia : * potassium carbonate sodium sesquicarbonate asd go sesquicarbonate 0 or mixtures thereof potassium bicarbonate potassium carbonate tartaric in mixture with at least one non-toxic organic acid; Acceptable Physiology such as citric fumaric fumaric or adipic gluconic gluconic 0181616 salicylic 9116(116; adipic succinic succinic sodium or potassium phosphate acid) sodium Sodium fumarate: 10108:818 1 or “betaine hydrochloride hydrochloride (lis sodium or potassium acid phosphates) The furin-generating agents of which malic mixtures are mixed. Preferably from these acids is malic acid, such as persalts It is effective under alkaline pH conditions including peroxide salts ' ; alkali and alkaline earth metal peroxoborates

Lo «percarbonate »persulphates as well as perborates 0610018168 Persulfate v, example; Jp and mixtures thereof as previously described on perphosphates | mono- or tetrahydrate ¢ SLY) perborate alkali metal A mixture of alkali metal perborate as monopersulphate with an anhydrous, mono- or tetrahydrate which is a 1:1 mixture of 15 1 du Point de Nemours sold from Caroat® and potassium bisulfate. potassium sulphate cmonopersulphate persulfate vo 8,0 which has an active oxygen content of about potassium bisulphate

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VY | + in preferred formulations suitable for use as denture cleaners; The solid base material comprises a pair of (B) carbonate/varic acid optionally in combination with an oxygen effervescent generator: 1 perborate/persulphate. The combination of generators is valuable in order to achieve good dissolution properties and pH conditions to achieve optimal cleaning. and antimicrobial activity. 0 The constituents of (B) carbonate generally include from about dye to about 7716 preferably from about 8 to 700 of the total composition; The acid constituents generally comprise from about 70 to about 0 preferably from about 01 to about +77 of the total composition. The bleaching compositions of the invention may be supplemented by other ingredients known to these preparations. A particularly preferred additive is a corganic peroxyacid precursor 0 which can generally be defined as a compound having at least 0.10 mL of 1,1 N sodium thiosulfate in a test peracid preparation the next. A test solution was prepared by dissolving the following substances in 1,000 milliliters of distilled water: (Na,P,0,.10H,0) sodium pyrophosphate 8 g (NaBO,.H,0,.3H,0) sodium perborate It has available oxygen 961.4 g, + sodium dodecylbenzene sulphonate 8 g to this solution at 220 liad an amount of activator such that each atom of 0 available oxygen has one gram molecular equivalent of the activator. : | The resulting mixture is stirred vigorously by adding the activator and kept at 10°C. After five minutes of CE, a portion of 100 milliliters of the solution is withdrawn and dripped with a pipette directly into a mixture of You g crushed ice and 11 milliliters of glacial acetic acid. Then add potassium iodide (8+ —) | M and immediately crush the liberated iodine with (+ 111050101816 N) sodium with starch as an indicator until the first disappearance of the blue color. The amount of sodium thiosulphate solution used in milliliters is the volumetric standard for the bleach activator. Organic peracid precursors are typically compounds containing one or more acyl groups [cacy] that are subject to epihydrolysis. perhydrolysis .685) Preferred activators of the N-acyl or O-acyl compound type containing a vo-acyl R-CO moiety where R is a hydrocarbon or a preferred substituent hydrocarbon group Yay | z

A: 0 carbon atom. Examples of peroxide sources include Ye to about 1 to have of about : suitable: : is RCO where (RCONR|R; of the formula acyl . organoamides are acyl organic amides (1) and with [ acyl radical B18 is a carboxylic acyl radical Carboxylic acyl radical: As described in US Patent No. organic radical is an organic radical 0 Examples of compounds within this group These include: .21171 EA ¢N-acetylphthalimide 5 N,N-diacetylaniline (0 ¢N,N'-diacetyl-5,5-dimethylhydantoin as ¢N-acylhydantoins (b) N,N,N' ,N'-tetra acetyl ethylene diamine as “polyacylated alkylenediamines (—s) is described as the corresponding LS (TAHD) hexamethylenediamine and derivative (TAED) 1,063-4-907,358; GB-A-907,357 GB-A-907,356 in : as ctetraacetylglycoluril as cacylated glycolurils D-contained glycolchlorylates. GB-A-1,247,429 5 GB-A-1,246,339 «GB-A-1,246,338 is described in

N-methyl-N-benzoyl-menthane sulphonamide similar to “acylated sulphonamides (Y) CMSA is described as N-phenyl-N-acetyl menthane- sulphonamide Vo .GB-A-3,1 83,266 (GB-A- 836,988 in is age aL Scarboxylic esters (Y) Compounds of this type le itd .GB-A-1,147,871 5 GB-A-963,135 1 ; -nitrobenzaldehyde diacetate “fructose pentaacetate” sorbitol hexaacetate Y. Examples: acetyl slicylic acid y “acetyl aceto hydroxamic acid” isopropeneyl acetate with substituted phenol J sid or phenol from other phenol esters are Esters of chloroacetylphenol JA. calpha-chlorinated lower aliphatic carboxylic acid as described in US Patent No. cchloroacetylsalicylic acid

AR y 15 Yo of acyl moiety is the acyl moiety Ac Cua Ac L has the general formula carboxylic esters (4)

CC, alkyl or alkenyl Cg-Cpp The alkyl or alkyl fraction includes organic carboxylic acid Yay yo

Cg-Cop alkyl substituent Cg-Cog branched or linear; Optionally substituted or the alkyl part conjugate acid the conjugate acid leaving group and 1 is a leaving group 10 which has 01658 in the range from 4 to 16 for example oxybenzene sulfonate 0 preferred compounds of this type 0Xybenzoate or Oxybenzoate oxybenzenesulfonate are those where: 0 : : + branched or linear containing of an alkyl group is the alkyl group Ry R;-CO Ac (a) preferably more than 7 to 4 carbon atoms and where that OY series to 1 to 10; Longer linear carbonyl carbon is preferred extending from and includes the alkyl carboxyl carbon optionally substituted Ry carbon atoms; 01 preferably 0 to VA z containing from © to or 00113 (Br « Cl by (carbonyl moiety to the carbonyl moiety alpha Wl (preferably 1) Examples of this class of substance include: LOC,H; sodium 3.5,5-trimethylhexanoyloxybenzene sulfonate, sodium 3,5,5- trimethylhexanoyloxybenzoate, sodium 2-ethylhexanoyl oxybenzenesulfonate, sodium nonanoyl oxybenzene sulfonate and sodium octanoyl oxybenzene sulfonate, 1 Vo Ry where Ry(AO), XA (b) ah has the formula \ i + preferably from Yo to 1 or a branch containing from (sha alkyl or alkylaryl group ; optionally substituted by Ry is calkyl moiety carbon atom in the 11th alkyl moiety to Y. Or oxyethylene cul is oxy AO is “OCH; or “<OCH;3” Br “Cl “CO -NR; R «CO-CO «CO dmo Ag alkylene B©-,© y is alkyl alkyl is 0-0 alkyl Ry is GAA to 1 contains from alkarylene or arylene calkenylene Yo walkylene or alkenylene moiety compounds include carbon in the alkylene or alkenylene part carbonic acid derivatives of this type bleach activator derivatives

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Of the formula ¢R3(A0),OCOL succinic acid derivatives of the formula glycollic acid derivatives «li ie (R;OCO(CH,),COL of the formula (R;OCH,COL) hydroxypropionic acid derivatives of the formula (R;OCH,CH,COL) oxalic acid derivatives of the formula «R;0COCOL ° and fumaric acid derivatives 031616 of the formula <(R3OCOCH=CHCOL) acyl aminocaproic acid derivatives of formula (R3CONR(CH,)4COL) op «acyl glycine derivatives of formula (R3CONR{CH,COL) and amino-6-oxocaproic acid derivatives of formula RNR, ) CO(CH,,COL) above; preferably © is from zero to R35 00 ! ) and when 10 is nonzero, the group LAS is as specified above cacyl-cynaurates (©) as tribenzoylcyanurates or criacetyl- as described in US Patent Specification No. TYTYAAY 0 (1) anhydrides ai wae optionally substituted anhydrides of phthalic acid benzoic on the exemplary m-chlorobenzoic anhydride “benzoic anhydride .phthalic anhydride 4 (VY) N-source compounds N-acylated precursor compounds of the lactam class as sa generally described in “GB-A-855735 especially caprolactams; valerolactams and caprolactams 7 such as benzoyl caprolactam “benzoyl valerolactam” and substituted benzoyl analogs, including chloro derivatives, the amino camino alkyl aryl and the alkoxy of the above. above; Prefer organic peracid sources 0160075015 Organic peracid of type 1 C) E (I) and L. If found; The level of peroxyacid bleach precursor ve by weight of the total formulation is preferably from about 70:1 to about 01 preferably more than about 70.9 to about 70 and is generally added in the form of aggregates bleach precursor. agglomerate ْ Yay z

Therefore, the aggregate of the ovarian source preferred for use here generally includes a binder or agglomerating agent at a level of about 70 to about fe, preferably from about 0 to about 771 of its weight. Suitable laxative agents include “polyvinylpyrrolidone (oxyethylene) oleander of Sa 000001 to 200039604 m polyethyleneglycols of about 0001 to about 0001 molar weight of Carbowax of 00800 to 10000”; Non-ionic surfactants 10710016 Sodium carboxymethyl cellulose “fatty acids” gelatin cfatty alcohols phosphatases “clays Jala” polyphosphates 5 phosphates polymeric polycarboxylates y aluminosilicates of the above; Jabs strongly cpolyethyleneglycols 0 especially having a molecular weight of about 0001 to about 200010 0001 day to about .00001 Judd is preferred in terms of solubility and pH properties of a bleach source aggregate that includes from about 701 to about VO preferably from about 71// to about 68 of its weight source of peracid bleach; And from about Hye about 7780 preferably from about 15 to about 0 150 preferably more than about 101 to about 750 pairs of (bi) carbonate aes and from about braiding to About 771 piproxoborate 06100001818 and from about 06100001818 and from about 0.01 to about 746 preferably from about 01 to about 771 agglomerating agent. It is preferable to have granules; the source of the final ovary average particle size from about *00 to about 0001 preferably from about 0 0 to about 0001 μm”; this is beneficial in terms of optimizing dissolution performance and taste aspects. More than about 70 about 110 by weight of the formulation The bleaching composition of the invention may be in the form of paste, tablet, granular or powder The formulations in tablet form may be single or multi-layered tablets The anal formulations of the invention may be supplemented with components Others familiar to these formulations; Yo especially surfactants as generally described above, chelating agents, enzymes, coenzymes, dyes, sweeteners, tablet binders and fillers, foaming agents, dimethylpolysiloxanes, Jie, foam stabilizing agents. As a Yay fatty acid ester sugar |

YA d cfatty acid sugar esters preservatives; lubricants such as talc; cmagnesium stearate; amorphous pyrogenic silicates; fine, smooth; etc.. Jal so includes a binder and disc gasket suitable for use here “polyvinylpyrrolidone poly (oxyethylene) 0 has a molecular weight of about 00001 to polyethyleneglycoles © vv ov has a molecular weight of about 0001 to about 61,008,568©; Carbowax has a molecular weight of 5050860 to: 0 nonionic surfactants “fatty acids” sodium carboxymethyl cellulose gelatin fatty alcohols “calcium carbonate “sodium carbonate “polymeric polycarboxylates” clays Jwala | “magnesium hydroxide carbonate” magnesium oxide “calcium hydroxide 0” “sodiumsulfate” protein “cellulose esters” cellulose ethers “proteins” alginic acid esters “polyvinyl alcohol” materials Vegetable fatty acids with a pseudo-colloidal nature.From the above, opolyethyleneglycols are highly preferred especially with a molecular weight of about 0001 to about 0000 preferably from about 10001 to about 1 Foon Vo chelating agents Agents useful in the sacl wall on the hal and stabilizing: the ovary by keeping cmetal ions such as calcium magnesium 8060 and heavy metal cations in solution. sodium acid pyrophosphate aminopolycarboxylates < tetrasodium pyrophosphate nitrilotriacetic acid / ethylenediamine tetracetic acidy 0 and ethylenediamine-N,N*disuccinic acid 3 (EDDS) and terminated salts and polyphosphonates and aminopolyphosphonates “ethylenediamine tetramethylenephosphonic acid <hydroxyethanediphosphonic acid diethylenetriaminepentamethylenephosphonic acid” and 5 salts thereof. The chelating agents chosen are not critical except that they must be compatible with the other ingredients in the denture cleaner vo when in a dry state and in an aqueous solution. The grappling agent includes; By distinguishing between 1.1 and 7710 of the formula weight, preferably between 0.0 Fog, with this it is preferable to include Yay gamma

To about 0.11 to about 1 preferably from about 11 to about phosphonic acid chelates about 8.09 of the weight of the formula. Alkalase proteases are suitable for use here in enzymes represented by enzymes fungal and bacterial lipases camylases calkalases esterases cglucanases glucanases cmutanases dextranases dextranases and peroxidases lactases pectinases cellulases esterases 351495170 etc. Suitable enzymes are discussed in US Patent No. 08 ALMAFA also describes the following examples and reviews preferred embodiments within the scope of the present invention. industrial according to the invention. Lod ratios are the total disk weight. Tablets are made by compressing a mixture of granular ingredients in a press of the type . kPa 2 Js male and female to make a disc when pressed huh 3 Y Y \ ee ————————————”————————————————— ———————————— \¢ - Yo A VY Malic Acid - 86 - a - A ~ Citric Acid : 1 01 01 A Ye Sodium Carbonate 7 ¥ - - ° Sulphamic Acid ° A l 7 - PEG 20,000 - - - and 1 PVP 40,000

Y¢ YY Yo 4 Yy Sodium Bicarbonate / Yo 31 11 1 1 Sodium Perborate monohydrate : "3 - 1 1 Potassium Monopersulphate - 1 1 1 - Pyrogenic Silica - - - - Y Talc 7 - 1 - - EDTA - 1 - = 1 ()EDTMP

Y \ Y 1 Y (°)Flavor Flavor 1 Y «0 yo 1 (9Magnasoft Fluid 01 17-00 A 4 Bleach Precursor Agglomerate Bleach Source ol)

Bleach Precursor Agglomerate

Y,o ° 3 - Y () TAED - - - L "005 Basun Y Y Y Y Sulphamic Acid

Y oo oY oY we Sodium Bicarbonate y,o "ra Y,¢ 7 ¥,e PEG 6000

Yay

.,0 * A - Dye Ethylenediaminetetramethylenephosphonic acid (1): L-Tetraacetylethylene diamine (Y)

Sodium 3,5,5-trimethylhexanoyloxybenzene sulfonate (¥)

OSI by Magnasoft Fluid (£) Peppermint base flavor (0) 0 mm. YO to © above; The total disc weight is ¥ g; Diameter 1 in the examples 018908 denture cleaning tablets exhibit anti-plaque activity and improved anti-bacterial activity with excellent adhesion and other physical properties and performance during use. To ?ahd and a representative antimicrobial according to the invention. The proportions are g B05 for the following perfume formulations; Flavor; Lad ve percent of total formula weight. 9 A : 1

Ye £,0 ooo Yo PPG-5-ceteth-20 Ra 6ml - PEG-40 Hydrogenated Castor Oil

PEG-40 hydrogenated castor oil - - - L : Trideceth-12 906 - 6 - 0 L . Y, 0 A Y y* flavor(*) _ — v. - (1) she — - m" oY ad trimethylbutane 0

Trimethyl butanamide / 4,0 + - - Triclosan \, ov m m | (#)Magnasoft Liquid ' <—————% es water > to -_ es Mainly used to smell trendy. Cla gia Perfume is a complex mixture of (1) Perfume compositions reveal flavor ; Refrigerant and/or antimicrobial Examples 1 through 95 exist. the effectiveness of the Ss improvers on the surface; effect

Yay

Claims (1)

1 Protection alice Comprises: cleaning composition 1-1 taminoalkyl silicone Y tinorganic persalt bleaching agent inorganic persalt bleaching agent y $ lipophile selected from the group consisting of flavoring agents; Perfumed, An gf gaudy ° anti-microbial and a mixture thereof. ,. Claim 1 Where dL Scleaning composition -Y 0 aminoalkyl silicone Y has an aminoalkyl siloxane content of approximately 960.1 to approximately repeating unit basis on a 7 v 01 repeat unit basis *- The cleaning composition as in claim 1 where lipophile Y is a flavoring agent. 1 4- The cleaning composition as in the oF protection element, where the flavoring agent 1 is chosen from the group consisting of ewintergreen oil oregano oil coregano oil v bay leaf oil dbay leaf oil Peppermint oil 080060711171 ¢ spearmint oil clove oil sage oil Cay oil corange oil orange oil demon oil lemon oil esassafras 011 sassafras 1° anise canise oil benzaldehyde bitter almond oil zeith | smarjoram oil cedar leaf oil 3 leaf oil ccamphor camphor 7: mustard oil castor oil ddavendar oil lavender oil ccitronella oil citronella A rosemary oil pine needle oil pine needle oil peach q Leis and mixtures “cinnamon leaf oil thyme oil thyme oil 1 0 #- cleaning composition composition 1601108 as In claim 1a, where aminoalkyl silicone Y is an aminoalkyl silicone hydrophobic noncyclic noncyelic v having a formula comprising two basic units: me JY osSn ar 1 os Sint m where RDER)SiOUmny2 (1) ¢ SY or 1 is zero or ° YY RY, RDO aby: (7). Alkyl and alkenyl A from about 1 to about 10 carbon atoms optionally substituted with a 4-fluoro or cyano-hydroxy group (calkoxy and acetoxi) : is: R and is acetoxy Ve R R? Rs Xx J rps 1 1 carbon atom 1-71 of about 01721601 alkylene valence SU where 183 is alkylene 1: Aldine ry optionally or optionally intersected by atoms 0; 84 RS and 26 which may be vt identical or different and be selected from the 11 alkyls of about Your carbon atom substituted: vo or optionally intersected by N and or X50 atoms being monovalent anion 1 010001781601 and also Lexie containing aminoalkyl silicone from about 0.1 to 7 about 967 of unit (1) on a repeat unit basis. 1 01 cleaning composition p0168010 as in protection element 0 where aminoalkyl silicone has a molecular weight of at least about Coes 0 > 7- cleaning composition as in ileal jae 0 where: : 00001 to about ©0000 having a molecular weight of about 1 aminoalkyl silicone Y | +- the cleaning composition as of claim 1; Cua The | ; Co contains from about 960.01 to about 9675 by weight cleaning composition Y .aminoalkyl silicone ¥ 1 4- The cleaning composition as in claim 1 where the Y composition includes cleaning cleaning composition ranges from about 960.11 to about 965 by weight .aminoalkyl silicone v -01 y cleaning composition as in claim 1 where the hydrophilic substance: is a perfume composition. As in Protection Vo, where the perfume composition includes one or more perfume ingredients selected from the group consisting of: YY geranyl acetate, linalyl acetate, citronellyl acetate, dihydromyrcenyl acetate, terpinyl 0 acetate, tricyclo decenyl acetate, tricyclodecenyl propioniate, 2-phenylethyl ¢ acetate, benzyl acetate, benzyl salicylate, benzyl benzoate, sytrallyl acetate, ° amyl salicylate, methyl di hydrojasmonate, phenoxyethyl isobutyrate, neryl 1 acetate, trichloromethyl-phenylcarbinyl acetate, p-tertiary butyl-cyclohexyl 7 acetate, isononyl acetate, cedryl acetate, vetiveryl acetate, benzyl alcohol, 2- A phenylethanol, linalool, tetrahydrolinalool, citronellol, dimethylbenzylcarbinol, 9 E :, dihydromyrecenol, tetrahydromyrcenol, terpineol, eugenol, geraniol, vetiverol, 01 3-isocamphyl-cyclohexanol, 2-methyl-3-(p-tertiary butylphenyl)-propanol, 2- 1 methyl-3-(p-isopropylphenyl)-propanol, 3 -(p-tertiary butylphenyl)-propanol, VY nerol, alpha-n-amylcinnamic aldehyde, alpha-hexyl-cinnamic aldehyde, 4-(4- Vy hydroxy-4-methylpentyl)-3-cyclohexenecarbaldehyde, 4-(4-methyl) -3-pentenyl)- Ve 3-cyclohexenecarbaldehyde, 4-acetoxy-3-pentyl-tetrahydropyran, 2-n-heptyl- Vo «cyclopentanone, 3-methyl-2-pentyl-cyclopentanone, n-decanal, n-dodecanal vy hydroxycitronellal , phenylacetaldehyde dimethyl acetal, phenylacetaldehyde VY diethyl acetal, geranonitrile, citronellonitrile, cedryl methyl ether, VA isolongifolanone, aubepine nitrile, aubepine, heliotropine, coumarin, vanillin, Va diphenyl oxide, ionones, methyl ionones, isomethyl ionones, irones, cis -3- 7 : hexenol 71 : “isochroman musks ctetralin musks “indane musks from that; esters and esters YY “macrolactone musks” macrocyclic Ketones 3 j——S Ala YY ketones and mixtures thereof. aromatic nitromusks “ethylene brassylate Yt choose the Cus agent as in the protective element cleaning composition 1-17 from group inorganic persalt bleaching agent 1 and mixtures thereof. percarbonates «perborates »alkali metal persulphates consisting of v Y¢ wherein Agent 1 as protective ingredient cleaning composition 4,€ 5-1 > 1 0 P contains about inorganic persalt bleaching agent Y .cleaning composition To about 9670 by weight of the cleaning composition v Cua ¢) as the protective agent The cleaning composition includes 1-4 0 of the inorganic persalt bleaching agent Y . cleaning composition From the weight of the cleaning composition 9080 to about 01 Js x wherein addition 1 as in the protection element cleaning composition -1#1 .effervescence generator includes a Y fizzing generator wherein it includes Generator V0 as in protection cleaning composition Cleaning composition -1” 1 : of bicarbonate Cus acid var; {(bi) carbonate effervescence generator furan Y group consisting of: r “sodium sesquicarbonate “sodium carbonate” sodium bicarbonate ¢ and mixtures thereof; Whereas, potassium bicarbonate “potassium carbonate °” malic acid “citric acid “fumaric acid “tartaric acid” is chosen from the group consisting of 1 adipic acid “slicylic acid” succinic acid “maleic acid 40 v” sodium acid phosphates sodium fumarate “sulphamic acid” or A or mixtures thereof. cbetaine hydrochloride 9 wherein the components of V1 as the protective ingredient cleaning composition 1-17-1 d/e comprise of approx. * To about 96,765 by weight of the cleaning composition, bicarbonate Y: by weight of %o The acid components include from about * to about cleaning composition v .cleaning composition $ For cleaning dentures by applying to dentures a composition method Method—YA 1 inorganic caminoalkyl silicone inorganic bleaching agent comprising Y selected from the group consisting of lipophile and lipophilic persalt bleaching agent v flavoring agents; physiological coolants; Antimicrobial and mixtures thereof. ¢ has a content of aminoalkyl silicone cia (VA) as in protection element † method = Y4 1 iteration. sang based on %Y from about 960.1 to about aminoalkyl siloxane Y